What are the main uses of tetrabutylammonium fluoride trihydrate (Tetra-N-Butylammonium Fluoride 3H2O)?
Tetrabutylammonium fluoride trihydrate has a wide range of uses. In the field of organic synthesis, it is often used as a fluorination reagent. This reagent can introduce fluorine atoms into organic molecules. The unique properties of fluorine atoms can significantly change the physical and chemical properties of organic compounds, which is of great significance in pharmaceutical chemistry, materials science, etc.
In organic reactions, it can assist many reactions. For example, nucleophilic substitution reactions, which can react with substrates such as halogenated hydrocarbons to form fluorinated organic products due to the nucleophilicity of fluorine ions. In the total synthesis of some complex natural products, tetrabutylammonium fluoride trihydrate also plays a key role in assisting chemists in the construction of target molecules.
In the field of materials science, it may participate in the preparation of fluorinated materials. Fluorinated materials often have excellent properties, such as corrosion resistance, low surface energy, etc. By using this compound, the composition and structure of the material can be precisely adjusted to meet the needs of different application scenarios.
In the deprotection reaction, tetrabutylammonium fluoride trihydrate also shows unique performance. Some silicone protective groups can be selectively removed without affecting other functional groups in the molecule, which facilitates the advancement of organic synthesis steps.
Overall, tetrabutylammonium fluoride trihydrate is an important chemical reagent in many fields such as organic synthesis and materials science, enabling chemists to explore and create a variety of organic compounds and new materials.
What are the storage conditions for Tetra-N-Butylammonium Fluoride 3H2O?
The storage of tetrabutylammonium fluoride trihydrate should not be careless. This is determined by the characteristics of the substance.
This substance should be placed in a cool place, away from direct sunlight. Cover the heat of the sun, which can make the properties of the substance change, causing it to lose its original effect. If it is overheated or decomposed, it will endanger the safety of storage.
And it needs to be stored in a dry environment. Because it is afraid of moisture, if water vapor invades, it is easy to cause deliquescence and damage its purity and quality. The storage place should be equipped with moisture-proof equipment, and it is better to have a desiccant or the like to keep the environment dry.
Furthermore, sealed storage is essential. Its nature is lively, in contact with the air for a long time, or with its components, such as oxygen, etc., resulting in deterioration of quality. Therefore, it must be contained in a sealed device to prevent it from being transferred to the outside air.
And it should be kept away from fire and heat sources. This substance may be flammable, and in case of open flames and hot topics, it is dangerous to burn and endanger the safety of the surrounding area.
When stored, it should also be separated from oxidizing agents, acids and other foreign substances. Because of its chemical properties, if it coexists with them, it may cause violent chemical reactions, causing explosions, leaks and other disasters.
All these are the key to the storage of tetrabutylammonium fluoride trihydrate, which must be strictly followed to ensure its quality and safety.
What are the precautions in the use of tetrabutylammonium fluoride trihydrate (Tetra-N-Butylammonium Fluoride 3H2O)?
When using tetrabutylammonium fluoride trihydrate (Tetra - N - Butylammonium Fluoride 3H 2O O), many matters need to be paid attention to.
First, this is a strong alkaline compound and is corrosive. When taking it, be careful to avoid contact with the skin and do not let it into the eyes. If you accidentally touch it, rinse it with plenty of water quickly. If you feel unwell, seek medical attention urgently.
Second, this substance is quite sensitive to air and moisture. Therefore, when storing, it should be placed in a dry, cool and sealed place to prevent moisture and deterioration. After opening the package, it should be used as soon as possible. If it is not used up, it should be properly sealed and stored.
Third, when used in chemical reactions, the dosage should be precisely controlled according to the needs of the specific reaction. Due to the amount of dosage, it has a significant impact on the reaction process and product generation.
Fourth, because fluoride ions have unique chemical activities, it is necessary to pay attention to the compatibility of other substances that react with them when using. Some substances are mixed with it, or cause violent reactions, or reduce the reaction efficiency.
Fifth, during use, the ventilation of the experimental environment is essential. Ensure air circulation in the experimental site to prevent volatile gas from causing damage to the human body.
In general, when using tetrabutylammonium fluoride trihydrate, it is necessary to be careful and follow relevant specifications and procedures, so as to ensure the safety and smoothness of the experiment.
What are the physical and chemical properties of Tetra-N-Butylammonium Fluoride 3H2O?
Tetrabutylammonium fluoride trihydrate is a commonly used reagent in organic chemistry. Its physical properties are white crystalline at room temperature, deliquescent, and easily soluble in polar solvents such as water, ethanol, and acetone. Looking at its appearance, it often shows the appearance of white crystals, resembling fine snow, delicate and pure. Its melting point is about 80-90 ° C. This characteristic makes it possible to control the phase transition under specific temperature conditions, which is of great significance in chemical experiments and industrial preparation processes.
As for its chemical properties, fluorine ions in tetrabutylammonium fluoride trihydrate are nucleophilic and can act as offensive reagents in many nucleophilic substitution reactions. For example, when encountering halogenated hydrocarbons, fluorine ions can replace halogen atoms by means of nucleophilic force, thereby forming a new carbon-fluorine bond. This reaction is widely used in the synthesis of fluorine-containing organic compounds. And because its ammonium positive ion part has a certain phase transfer catalytic performance, it can promote the efficient progress of the reaction in the two-phase system, so that the reaction that was difficult to occur due to interphase mass transfer obstacles can be carried out smoothly. And because of its moderate alkalinity, it can also play a role in some occasions where a moderately alkaline environment is required to promote the reaction process. However, compared with strong bases, its reaction conditions are milder, which can effectively avoid the risk of overreaction and ensure the purity and yield of the reaction product.
What is the market price range for Tetra-N-Butylammonium Fluoride 3H2O?
The price range of Tetra-N-Butylammonium Fluoride 3H2O (Tetra-N-Butylammonium Fluoride 3H2O) in the market often varies due to many reasons.
If the quantity is not large in ordinary shops, the price per gram may be between tens of dollars and hundreds of dollars. This is because its preparation method is slightly difficult, the raw materials used are also specific, and special regulations need to be followed during storage and transshipment, so the price is not low.
However, if it is a large purchase and negotiates with various suppliers, the price per gram may be slightly reduced. If the purchase quantity is in kilograms, the price per gram may fall to about twenty or thirty dollars.
Furthermore, the prices of different suppliers in the market are also different. Reputable merchants, because of their high quality and proper after-sales service, may have slightly higher prices; while new suppliers are competing for market share, the price may be slightly lower.
And the supply and demand situation of the market is also the main reason. If there are many people in demand at any time, and there are few suppliers, the price will rise; on the contrary, if the supply exceeds the demand, the price may fall. Therefore, the market price of tetrabutyl fluoride triammonium hydrate is about 20 to 30 yuan per gram, depending on the quantity, quality, supply and demand.