M Nitrobenzotrifluoride
Fluoride
m-NITROBENZOTRIFLUORIDE
Chemical Formula C7H4F3NO2
Molar Mass 191.11 g/mol
Appearance Colorless to yellow - liquid
Boiling Point 203 - 204 °C
Melting Point -34 °C
Density 1.377 g/cm³ at 25 °C
Vapor Pressure 0.13 kPa at 25 °C
Water Solubility Insoluble
Flash Point 88 °C
Odor Pungent
FAQ

What are the main uses of m-NITROBENZOTRIFLUORIDE?

M-nitrotrifluorotoluene has a wide range of main uses. In the chemical industry, it is often used as a key intermediate in organic synthesis. It can be used to derive many important compounds, such as synthetic medicines, pesticides and dyes.

In pharmaceutical manufacturing, it can be converted into pharmaceutical ingredients with unique curative effects through specific chemical reactions. For example, a specific chemical structure can be constructed through complex processes, which can be used to develop new drugs against specific diseases and benefit human health.

In the field of pesticide creation, it can be used as a starting material to synthesize highly efficient and low-toxic pesticide products. These pesticides can effectively control various crop diseases and pests, improve crop yield and quality, and are of great significance to agricultural development.

In the dye industry, dyes prepared from m-nitrotrifluorotoluene are brightly colored and have good light resistance and washable fastness. They are widely used in textile, printing and dyeing industries, giving fabrics rich and diverse colors.

In addition, in the field of materials science, the polymer materials involved in the synthesis have special physical and chemical properties, such as excellent heat resistance, corrosion resistance, etc., and are also important in high-end fields such as aerospace and electronics. From this perspective, m-nitrotrifluorotoluene plays an indispensable role in many industries and is of great significance in promoting the progress of various industries.

What are the physical properties of m-NITROBENZOTRIFLUORIDE?

M-nitrotrifluorotoluene is one of the organic compounds. Its physical properties are quite worthy of investigation.

Looking at its properties, it is mostly a colorless to light yellow liquid under normal conditions, and this color state is easy to intuitively distinguish. Its odor is unique, irritating, and can be smelled. This characteristic is also one of its physical properties.

As for the melting point, the melting point is about -29 ° C, and the boiling point is between 230-232 ° C. Such melting point data are of great significance in practical application and storage. The low melting point makes it a liquid at room temperature; the higher boiling point indicates that more heat needs to be provided to vaporize it. < Br >
Its density is about 1.474g/cm ³, which is higher than that of water. This property plays a significant role in operations such as liquid-liquid separation. In the stratification phenomenon, m-nitrotrifluorotoluene will be in the lower layer.

In terms of solubility, the substance is insoluble in water, which is determined by its molecular structure. However, it is soluble in many organic solvents, such as ethanol, ether, etc. This solubility provides an important basis for the selection of suitable solvents in organic synthesis reactions.

In addition, the volatility of m-nitrotrifluorotoluene is relatively low, which can reduce the loss and harm caused by volatilization during storage and use. Its vapor pressure is also low, which is related to volatility, further indicating that the substance has a small proportion in the gas phase at room temperature and pressure.

Is m-NITROBENZOTRIFLUORIDE chemically stable?

M-NITROBENZOTRIFLUORIDE is m-nitrotrifluorotoluene, and its chemical properties are quite stable. In this compound, trifluoromethyl (-CF 🥰) has strong electron absorption, which reduces the electron cloud density of the benzene ring, making it difficult for electrophilic substitution reactions to occur. Nitro (-NO 🥰) is also a strong electron-absorbing group, and the synergistic effect of the two strengthens the molecular stability.

From a structural point of view, the electron cloud distribution of the benzene ring conjugated system changes due to the presence of electron-absorbing groups, which weakens the activity of the benzene ring. Under normal conditions, m-nitrotrifluorotoluene is not easy to react with common reagents such as weak acids, weak bases and most oxidants and reducing agents. < Br >
In the field of organic synthesis, due to its stability, it is often used as a reaction intermediate and participates in the construction of more complex molecular structures. For example, after a specific reduction reaction, nitro groups can be converted into amino groups, while trifluoromethyl groups remain stable, laying the foundation for subsequent synthesis.

In terms of storage, due to its stable chemical properties, it can be properly stored at room temperature and pressure without special harsh conditions as long as it avoids high temperature, open flame, strong oxidants, and strong reducing agents.

In short, m-nitrotrifluorotoluene is chemically stable, which makes it widely used in many fields of organic chemistry and has important value in organic synthesis, materials science, etc.

What is the preparation method of m-NITROBENZOTRIFLUORIDE?

The method of preparing m-nitrotoluene is achieved by nitrification with trifluorotoluene as the starting material. This reaction usually uses mixed acid (a mixture of sulfuric acid and nitric acid) as the nitrifying agent.

In a suitable reaction vessel, first place trifluorotoluene, and then slowly add the mixed acid under low temperature and stirring conditions. Sulfuric acid plays a dual role here, one is to enhance the nitrification activity of nitric acid, and the other is to act as a dehydrating agent to promote the reaction in the direction of generating m-nitrotrifluorotoluene. Nitric acid is a key reagent for nitrification and can provide nitro (-NO 2).

The reaction formula is roughly as follows: CF < C > H+ HNO < Br > (catalyzed by H < SO <) → CF < C < H > NO < O + H < Br > During the reaction, temperature control is crucial. If the temperature is too high, side reactions such as polynitrification are prone to occur, resulting in a decrease in product purity; if the temperature is too low, the reaction rate will be slow and take a long time. Generally speaking, the reaction temperature should be maintained at 0-10 ° C.

After the reaction is completed, the product needs to go through a post-treatment process to obtain a pure product. A common post-treatment step is to pour the reaction mixture into ice water to separate the product from the mixed acid. After extraction with an organic solvent, the commonly used organic solvents are dichloromethane, ether, etc. The extract is dried with a desiccant such as anhydrous sodium sulfate to remove the moisture. Finally, by distillation and other means, the organic solvent is removed and the fraction in a specific boiling point range is collected to obtain m-nitrotrifluorotoluene.

There are also other preparation methods, such as using m-nitrobenzoic acid as a raw material and preparing it by trifluoromethylation. However, compared with the nitration method using trifluorotoluene as the starting material, this method is more complicated and costly, so the nitration method is used in industry to prepare m-nitrotrifluorotoluene.

What are the precautions in storage and transportation of m-NITROBENZOTRIFLUORIDE?

M-nitrotrifluorotoluene is a chemical substance. When storing and transporting, many matters need to be paid attention to.

When storing, the first location should be selected. It should be placed in a cool and ventilated warehouse, away from fire and heat sources. It is easy to cause danger due to hot topics or open flames. The temperature of the warehouse should not be too high to control it within a suitable range to prevent its chemical properties from changing. And it should be stored separately from oxidizing agents, reducing agents, alkalis, etc., and must not be mixed. Otherwise, it is easy to cause chemical reactions and cause accidents.

Furthermore, the packaging should be strict. Make sure that the container is well sealed to avoid leakage. If the package is damaged, m-nitrotrifluorotoluene escapes, which not only damages the material, but also endangers the environment and people. The storage area should also be equipped with suitable materials to contain the leakage for emergency response.

As for transportation, the transportation vehicle must meet safety standards. Drivers and escorts must be professionally trained and familiar with its nature and emergency handling methods. During transportation, they should be protected from exposure to the sun, rain and high temperature. When the road is bumpy, it is also necessary to ensure that the package is stable and will not be damaged by collision.

When loading and unloading, the operation should be gentle, and the package should not be loaded and unloaded brutally to avoid damage. During transportation, the relevant documents must be complete, and the route must be followed, avoiding densely populated areas and important places, so as to ensure the safety of storage and transportation.