Chemical Formula | C7H6F3N |
Molecular Weight | 161.13 |
Appearance | Colorless to light yellow liquid |
Boiling Point | Around 187 - 188 °C |
Density | 1.244 g/cm³ |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
Flash Point | Around 76 °C |
Vapor Pressure | Low vapor pressure at room temperature |
Odor | Characteristic amine - like odor |
What are the main uses of m-aminebenzotrifluoride?
M-aminotrifluorotoluene is a crucial raw material in the field of organic synthesis and is widely used in many industries.
First, in the field of pharmaceutical synthesis, this substance has extraordinary effects. The preparation of many drugs is based on m-aminotrifluorotoluene. Due to its special chemical structure, it can endow drugs with specific physiological and pharmacological properties. For example, in the development and production of some antidepressants and antibacterial drugs, m-aminotrifluorotoluene participates in key reaction steps, helping to build the core skeleton of the drug, which in turn determines the efficacy and activity of the drug.
Second, in the field of pesticide manufacturing, m-aminotrifluorotoluene is also indispensable. The creation of many efficient pesticides relies on its unique chemical properties. It can be used as an intermediate to generate pesticide products with high insecticidal, bactericidal or weeding properties through a series of chemical reactions. Such pesticides often have the advantages of low toxicity, high efficiency and environmental friendliness, which can effectively protect the growth of crops and improve agricultural production efficiency.
Furthermore, in the dye industry, m-aminotrifluorotoluene also plays an important role. It can be used as a key raw material for the synthesis of new dyes. With the color stability and dyeing properties brought by its chemical structure, dyes with bright colors, good light resistance and washable properties can be produced, which are widely used in textile, printing and dyeing industries to meet people's needs for the beauty and durability of textiles.
In addition, in the field of materials science, m-amino trifluorotoluene can be introduced into the structure of polymer materials through appropriate chemical reactions, thereby improving the properties of materials, such as improving the corrosion resistance and thermal stability of materials, and expanding the application range of materials in special environments. In short, m-amino trifluorotoluene plays an irreplaceable role in many fields due to its unique chemical properties, promoting the development and progress of various industries.
What are the physical properties of m-aminebenzotrifluoride?
M-amino trifluorotoluene is an important compound in organic chemistry. It has unique physical properties and is widely used in many fields.
In terms of appearance, m-amino trifluorotoluene is usually colorless to light yellow liquid, and it is clear and transparent. This appearance characteristic is easy to observe and distinguish in practical operation and application.
Its boiling point is about 187-188 ° C. As an important physical constant of substances, boiling point is of great significance for separation, purification and application under specific temperature conditions. Near this boiling point temperature, m-amino trifluorotoluene will change from liquid to gaseous state, and it can be separated or purified by distillation and other means.
The melting point of m-amino trifluorotoluene is about -34 ° C. Melting point characteristics determine its physical state at different temperatures. Below the melting point, it solidifies into a solid state; above the melting point, it is a liquid state. This needs to be taken into account during storage and transportation to ensure that it is in a suitable state.
The compound has a density of about 1.294 g/mL. Density can be used to determine its position in the mixed system and how it is separated from other substances. For example, in operations such as liquid-liquid extraction, effective separation can be achieved according to density differences.
m-Aminotoluene is insoluble in water, but soluble in organic solvents such as ethanol and ether. This solubility makes it possible to build a reaction environment with the help of suitable organic solvents in organic synthesis and related reactions, and it is also easy to separate from the aqueous phase system, improving the reaction efficiency and product purity.
In addition, m-aminotrifluorotoluene is volatile and will gradually evaporate in an open environment. This requires attention to sealing during storage and use to avoid losses due to volatilization and environmental impact. At the same time, its volatility will also affect the air quality in the workplace, and protective measures such as ventilation need to be taken to ensure the health and safety of operators.
What are the chemical properties of m-aminebenzotrifluoride?
M-aminotrifluorotoluene is an important compound in the field of organic synthesis. It has the following chemical properties:
First, it is basic. The amino group (\ (- NH_ {2}\)) gives this compound a certain alkalinity. Due to the presence of lone pair electrons on nitrogen atoms, it can combine with protons (\ (H ^{+}\)), and can undergo protonation reactions in acidic media to generate corresponding salts. This property allows m-aminotrifluorotoluene to react with acids, which can be used to prepare various derivatives, and also plays an important role in some acid-base catalyzed reactions.
Second, nucleophilicity. The lone pair electrons of amino groups also make the compound exhibit nucleophilicity. It can attack electrophilic reagents, resulting in nucleophilic substitution reactions. For example, it can react with halogenated hydrocarbons, nitrogen atoms attack the carbon atoms of halogenated hydrocarbons, and the halogen atoms leave to form new\ (C-N\) bonds. This is a common method for constructing the structure of nitrogen-containing organic compounds.
Third, the reactivity of aromatic rings. The benzene ring in the molecule of m-aminotrifluorotoluene, because the amino group is the donator group and the trifluoromethyl group is the electron-withdrawing group, its electron cloud density distribution is affected by the two. The donator conjugation effect of the amino group makes the electron cloud density of the benzene ring o-site and the para-site relatively increase, so it is more likely to undergo electrophilic substitution reactions in the o-site and the para-site, such as However, the strong electron-absorbing induction effect of trifluoromethyl will weaken the reactivity of the benzene ring to a certain extent, and the overall reactivity needs to be considered comprehensively.
Fourth, stability. The presence of trifluoromethyl enhances the stability of the molecule. Due to the high bond energy of\ (C-F\), m-amino trifluorotoluene has a certain resistance to external factors such as heat and oxidation. In some synthesis processes that require more severe reaction conditions, it can maintain its own structural stability, which is conducive to the smooth progress of the reaction.
In summary, the characteristics of m-amino trifluorotoluene and trifluoromethyl present unique chemical properties and are widely used in many fields of organic synthesis.
What is m-aminebenzotrifluoride production method?
M-aminotrifluorotoluene, the preparation method, often using m-nitrotrifluorotoluene as the starting material, is obtained by reduction reaction. Due to the suitable properties of m-nitrotrifluorotoluene, it is a common starting material in the reaction path.
The reduction method mostly uses catalytic hydrogenation. This technique uses precious metals or other suitable catalysts to interact with m-nitrotrifluorotoluene under specific temperature and pressure conditions. Hydrogen is activated on the surface of the catalyst, and the nitro group gradually obtains hydrogen. After going through an intermediate state, it is finally converted into an amino group, resulting in m-aminotrifluorotoluene. In this process, the choice of catalyst is the key. Precious metals such as palladium and platinum have high catalytic activity and good selectivity, which can make the reaction efficient and directional. Temperature and pressure also need to be precisely controlled. If the temperature is too low, the reaction rate will be slow; if the temperature is too low, the reaction rate will be slow; if the temperature is too high, it may cause a cluster of side reactions. The same is true for pressure, and a suitable range needs to be found to ensure a smooth reaction.
In addition to catalytic hydrogenation, there are also people who use chemical reducing agents for reduction. For example, iron powder, zinc powder and other metals react with m-nitrotrifluorotoluene in an acidic medium. The metal provides electrons to reduce the nitro group. However, this method is more cumbersome than catalytic hydrogenation, resulting in more waste, which is slightly inferior to environmental protection and economic considerations.
In short, the catalytic hydrogenation method is a commonly used method for the preparation of m-amino trifluorotoluene due to its advantages of high efficiency and environmental protection. The chemical reduction method also has its applications in specific situations.
What m-aminebenzotrifluoride need to pay attention to when storing and transporting
M-Amino trifluorotoluene is also a chemical substance. When storing and transporting, pay attention to many matters.
The first to bear the brunt, the storage place should be cool and dry. This is because if the substance is in a humid and warm environment, it may deteriorate and damage its chemical properties. If placed in an open and humid place, it may interact with water vapor, causing chemical reactions, resulting in no quality.
Second, avoid open flames and hot topics. Because of its flammability, in case of open flames and hot topics, it is easy to cause fires, and even explode, endangering the safety of the surrounding area. Just like dry firewood in case of fire, it will explode instantly, so the place of storage and transportation is strictly prohibited from fireworks, and heat sources should also be kept away.
Furthermore, the storage container must be well sealed. If the seal is not good, the substance may evaporate outside, which will not only damage the material, but also pollute the environment, and the volatile gas or toxicity will endanger human health. Just like treasures are hidden in a box, if the box is not tight, the treasures are easy to lose and cause damage.
When transporting, the packaging should be firm and stable. To prevent the container from being damaged and the material leaking due to bumps and collisions on the way. The packaging material must also be adapted to the characteristics of the substance and not react chemically with it. If the load is still far away, the carrier must be firmly secured to keep the item intact.
In addition, the handling process must be handled with care. Avoid violent vibration and falling to prevent package damage. If you hold a fragile device and take care of it carefully, it can be complete.
And storage and transportation places should be equipped with corresponding fire and leakage emergency treatment equipment. Once something happens, it can be responded to in time to reduce the damage. If there is a risk of fire or leakage, there is no way to deal with it, and the disaster will spread and the harm will be exacerbated.