5 Cyano 2 Fluorobenzotrifluoride Alpha Alpha Alpha 4 Tetrafluoro M Tolunitrile
Fluoride

5-Cyano-2-Fluorobenzotrifluoride~Alpha,Alpha,Alpha,4-Tetrafluoro-M-Tolunitrile

Duxiu Chemical

Specifications

HS Code

748805

Chemical Formula C8H2F5N
Molecular Weight 209.1 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 147 - 148 °C
Density 1.424 g/cm³
Solubility Soluble in organic solvents
Flash Point 44 °C
Refractive Index 1.399
Chemical Formula C8H2F5N
Molecular Weight 209.1 g/mol
Appearance Liquid (usually)
Solubility In Water Low (due to fluorine - containing and cyano groups)
Solubility In Organic Solvents Good solubility in common organic solvents like dichloromethane
Packing & Storage
Packing 500g of 5 - Cyano - 2 - Fluorobenzotrifluoride in a sealed, labeled chemical - grade container.
Storage 5 - Cyano - 2 - Fluorobenzotrifluoride/Alpha,Alpha,Alpha,4 - Tetrafluoro - M - Tolunitrile should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly closed container to prevent leakage and exposure to air or moisture, which could potentially cause decomposition or reaction.
Shipping 5 - Cyano - 2 - Fluorobenzotrifluoride~Alpha,Alpha,Alpha,4 - Tetrafluoro - M - Tolunitrile is shipped in sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring safe transit to destination.
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5-Cyano-2-Fluorobenzotrifluoride~Alpha,Alpha,Alpha,4-Tetrafluoro-M-Tolunitrile
General Information
Historical Development
5-Cyano-2-fluoro-trifluorotoluene and α, α, α, 4-tetrafluoro-m-toluonitrile, these two things are gradually emerging in the field of chemistry. At the beginning, the research was not deep, and the understanding was still shallow. However, as time went by, the wise men worked hard to explore its properties and study its reactions. In the past, the synthesis method was not good, the yield was not high, and the quality was not enough. However, scholars did not give up their research. After trial and error, a new path was gradually opened. Improve the synthesis technique and optimize the reaction environment, so that the yield rises and the quality is better. As a result, these two are gradually reused in the fields of medicine and materials, and they add a new chapter to the history of chemistry, and the future is more and more bright.
Product Overview
Today there is a product called "5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-toluene nitrile". This material is unique and is important for chemical research. Its shape may be crystalline powder, with pure color and uniform quality.
In the reaction, it is often used as a key reagent, which can cause unique chemical changes. Its structure is exquisite, containing cyanide groups, fluorine groups and other groups, which interact to give it special activity.
Because of its large number of fluorine atoms, it has good stability and can maintain its properties in special environments. In the field of organic synthesis, it is often used by craftsmen to prepare novel compounds and contribute to the progress of chemistry. Research assistants explore the unknown chemical world and open up new paths.
Physical & Chemical Properties
Today there is a substance called "5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-methyl benzonitrile". The physical and chemical properties of this substance are quite critical. Its physical properties are related to the shape, color, smell, etc. Looking at its shape, it may be crystalline or liquid, and may change under different conditions. Above the color, it may be transparent and colorless, or slightly colored. The smell may have a special taste, or light or strong.
In terms of its chemical properties, it shows different performances in various reactions. Its cyano, fluoro and other functional groups give unique activities. In case of specific reagents, either an addition reaction or a substitution. Between redox reactions, there are also corresponding changes. Studying the physical and chemical properties of this substance can provide a solid foundation for its application expansion, synthesis improvement, etc., to help the development of various fields of chemical industry.
Technical Specifications & Labeling
There is a product today called "5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-methyl benzonitrile". To clarify its technical specifications and identification (product parameters), it is necessary to study its production in detail.
The production of this product is carefully selected from the first heavy raw materials. The product must be suitable for its properties before it can be of good quality. The measurements in between are fixed, and there is no difference at all.
As for the method of making it, it must be followed by the rules. Temperature and time are all important. After the product is formed, check its shape and test its quality, and each has its own standards. The color is correct, the taste is pure, and the quality is stable. The
logo should not be ignored. Write its name, composition and parameters in detail to make it clear at a glance. This is the main point of technical specifications and labels, which is related to the use and transmission of this thing.
Preparation Method
There are currently methods for preparing 5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-methylbenzonitrile, which are described in detail as follows. The raw materials are selected, and when appropriate reagents are taken, they are compatible according to specific proportions. The production process starts with a certain reaction and goes through several reaction steps. In the first step, under specific conditions, the raw materials interact to form an intermediate product. Then, this intermediate product is further reacted under other conditions and converted into another intermediate state. In this way, step by step, each step needs to precisely control the conditions, such as temperature, pressure, reaction time, etc. And during the reaction process, an activation mechanism is set to promote the efficient progress of the reaction. The product of 5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-methylbenzonitrile was finally obtained through multi-step fine operation. Its quality and yield depend on strict control of each link.
Chemical Reactions & Modifications
The synthesis of Guanfu 5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-toluenitrile is related to chemical reaction and modification, which is the focus of our research. The mechanism of the reaction is just like what ancient books say, and it needs to be explored.
The reaction of this compound is like the ancient method of alchemy, and the temperature and composition must be accurate. At the beginning, the reactants are combined in sequence, like soldiers in formation, each in its place. However, when reacting, it often encounters variables, just like the situation changes. Or because the conditions are not suitable, the product is impure; or because the reaction is not complete, the effect is not as expected.
If you want to change its nature, you should like a good doctor to distinguish the syndrome and find the crux of it. Or adjust the temperature to suit it; or change the reagent and find another way. In this way, you can hope to obtain pure things, increase their performance, achieve a good state, and add bricks to chemical research. For example, the ancients studied science and kept improving, so as to obtain the truth.
Synonyms & Product Names
In the field of chemical industry, new products have emerged one after another. Today, there is a thing called 5 - Cyano - 2 - Fluorobenzotrifluoride Alpha Alpha - 4 - Tetrafluoro - M - Tolunitrile. This substance is also very useful in the chemical industry.
Looking for its synonymous name, I have also heard of it. In the way of chemical industry, there are many things, which is common. The names of synonyms are different because of differences in processes or due to differences in regions. Although the synonyms of this product are not widely spread, they are also known to those who study fine chemicals.
As for the name of the product, it is also important in the industry. The name of the product, so it is easy to know and pass on. The trade name of this substance either highlights its characteristics or shows its effectiveness, in order to attract the eyes of the audience and help it spread in the world.
For those who study chemical industry, delving into synonyms and trade names, it can be seen that this product is in the context of the industry, knowing its origin and changes, and it is of great benefit to research and development and application.
Safety & Operational Standards
5-Cyano-2-fluorotrifluorotoluene and α, α, α, 4-tetrafluoro-m-toluonitrile are both important chemicals. Regarding their safety and operating standards, it is the most important and needs to be treated with caution.
Prepare these two substances in a well-ventilated place to prevent the accumulation of harmful gases. Operators must wear professional protective equipment, such as protective clothing, protective gloves and gas masks, to avoid direct contact with the skin and respiratory tract.
When taking raw materials, the measurement must be accurate, and the operation should be stable and slow to prevent splashing. During the reaction process, temperature, pressure and other conditions need to be strictly controlled, and the operation should be carried out according to the established procedures, and should not be changed without authorization.
After the reaction is completed, the separation and purification of the product should also follow the specifications. All utensils used should be washed, dried, and stored properly.
For storage, the two things should be placed in a cool, dry and well-ventilated place, away from fire and heat sources, and away from direct sunlight. At the same time, they should be stored separately from oxidants, acids, etc. to prevent dangerous reactions.
If you accidentally come into contact during operation, you should immediately rinse with a large amount of water and seek medical treatment if necessary. In the event of a leak, quickly evacuate unrelated personnel, turn on ventilation equipment, use suitable materials to absorb and collect the leak, and properly dispose of it. Do not discard it at will.
Strictly adhere to safety and operating standards to ensure smooth production, personnel safety and the environment.
Application Area
Today there is a product called "5-cyano-2-fluorotrifluorotoluene α,α,α, 4-tetrafluoro-m-methylbenzonitrile". This product is quite useful in various application fields. In the field of medicine, it may be the key raw material for the synthesis of specific drugs. With its unique chemical structure, it can help the precise construction of molecules to treat difficult diseases. In material science, special materials can be added to increase its stability and corrosion resistance, and it can be used in equipment required in special environments. And in fine chemicals, it is also an important cornerstone for the preparation of high-end chemicals, and can be derived from a variety of fine products, which can be widely used in industry and people's livelihood. This compound has potential in many application fields, and we need to explore it in depth to make the best use of it for the benefit of the world.
Research & Development
In the field of chemical industry, new substances have emerged. The research and creation of 5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-toluenitrile is related to the hearts of our chemical researchers.
This substance is unique in nature and widely used. When we study it, we must first study its theory, destruct its structure, and understand the rules of its transformation. In the laboratory, observe its response, measure its number, record it in detail and analyze it carefully. I hope to explore its best craftsmanship and seek high-yield and pure products.
On the way to research, although the thorns are full, why are we afraid? Every small progress, are happy. Thinking of the ancient research, perseverance, and eventually become a great cause. We should also carry on its ambition, committed to research and creation. Looking forward to the future, this product will shine in industry and business, contributing to the prosperity of the chemical industry, to promote the progress of the industry, and to recognize the ability of my researchers.
Toxicity Research
Study on the toxicity of 5-cyano-2-fluoro-trifluorotoluene α, α, α, 4-tetrafluoro-m-toluonitrile
The toxicity of 5-cyano-2-fluoro-trifluorotoluene α, α, 4-tetrafluoro-m-toluonitrile is being investigated. This chemical is being widely used in industry, but its impact on organisms is unknown, so it needs to be investigated in depth.
It was studied by various experimental methods to observe its effects on different organisms. First, small animals were used as samples to observe the changes in their physiology and behavior. With the help of cell experiments, we can study the effect of this substance on cells and observe its impact on cell growth and metabolism.
After research, 5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-toluenitrile has certain toxicity. In animals, it can cause physiological disorders and abnormal behavior; at the cellular level, it can interfere with the normal physiological process of cells. This result warns our generation that when applying this substance, we should be cautious and take proper protective measures to reduce its harm to organisms and the environment, and also provide a foundation for future related research and application.
Future Prospects
In today's world, science and technology are changing with each passing day, and the research of chemical substances is also changing with each passing day. Today, there are 5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-toluonitrile, which has endless future prospects in the eyes of my chemical researchers.
Its unique nature may open up new paths for the production of new drugs. On the road of medicine, I hope it can break the difficulties of difficult diseases and remove diseases for the common people. Or in the field of materials, it has emerged, making materials have extraordinary properties, such as strong and light, tough and corrosion-resistant, used in equipment and aerospace, to help the progress of the industry.
Although it is now or only just beginning to appear, I believe that with time and unremitting research, I will be able to shine brightly and show my outstanding demeanor on the scientific stage of the future, contributing to the well-being of mankind and achieving extraordinary achievements.
Historical Development
The industry of chemical industry is changing with each passing day, and new products are emerging one after another. Today, there is a compound of 5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-toluenitrile. Its beginning is like the beginning of a star.
In the past, all the sages were searching for the way of chemical industry. At the beginning of the research of this compound, there were many obstacles, the raw materials were difficult to find, and the techniques were not refined. However, all the sages were unswerving, and the changes over the years accumulated the experience of experimentation. Or the formula was increased or decreased, or the process was easier, and finally the method of preparation was obtained.
It was formed by its own method, and this product gradually became the most important in the industry. In the fields of medicine and materials, it has emerged and has a wide range of uses, promoting the chemical industry forward, like a boat on water, setting sail and forging ahead, contributing to the development of the industry, creating a prosperous scene.
Product Overview
Today there is a product called "5-cyano-2-fluoro-trifluorotoluene α,α,α, 4-tetrafluoro-m-toluonitrile". This chemical product has unique properties. The position of 5-cyano and 2-fluoro gives specific activities; the structure of trifluorotoluene increases its stability and special properties 。α,α,α, 4-tetrafluoro-m-toluonitrile part, also adds unique properties.
This substance is used in the field of chemical research, or has catalytic ability, which helps many reactions to proceed efficiently; or is the key to material synthesis, used to prepare materials with special properties. Although it has not been seen in ancient books, its potential value cannot be underestimated from the perspective of today's chemistry. It may lead to changes in the chemical industry, materials, and other industries, opening up new paths for scientific research and industrial development.
Physical & Chemical Properties
Today there is a thing called "5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-toluene nitrile". Its physical and chemical properties are quite important.
The color of this thing may be pure, without variegated dyes. Its state, at room temperature, or in a liquid state, flows freely, like the flow of a clear spring. Its taste may have a special smell, but it is not pungent and intolerable.
In terms of its chemistry, it has a certain activity. In a specific environment, it can react with various substances. The cyano, fluoro and other groups it contains give it unique chemical properties. The presence of cyanide groups may cause them to exhibit a special reaction path in some reactions; the characteristics of fluorine groups increase or decrease their chemical stability.
In the field of scientific research, exploring the physical and chemical properties of this substance can lay the foundation for many applications, such as material synthesis, drug development, etc., or it can play an important role.
Technical Specifications & Labeling
Today there is a product called "5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-toluene nitrile". Its process specifications and identification (product parameters) are the key.
To make this product, it is necessary to follow the precise process regulations. From the selection of raw materials, it must be high standard, and there are few impurities. The temperature, pressure and time of the reaction must be strictly controlled. The utensils used in the process should also be clean and sophisticated to avoid other changes.
On the label, the product parameters must be detailed. The proportion, purity geometry and properties of each element contained should be clearly marked. This is not only the proof of quality, but also the user knows the details and makes good use of it according to its nature. In this way, this product is refined to meet the needs of all parties.
Preparation Method
Preparation and formulation of 5-cyano-2-fluorotrifluorotoluene -α,α,α, 4-tetrafluoro-m-toluenitrile (raw materials and production process, reaction steps, catalytic mechanism)
To prepare 5-cyano-2-fluorotrifluorotoluene -α,α,α, 4-tetrafluoro-m-toluenitrile, the first need to carefully select raw materials. Take fluoride, nitrile compounds as base materials, the purity of the product quality, must be carefully selected.
In the production process, the reaction step is the key. First put the raw materials into the reactor in a specific ratio, and control the temperature in a suitable range, such as a certain temperature range (determined according to the reaction characteristics), to ensure the orderly reaction. In the process, the addition of catalysts is indispensable. High-efficiency catalysts are selected to accelerate the reaction rate and improve the yield by means of their catalytic mechanism.
During the reaction, closely monitor and fine-tune the parameters according to the reaction process. After the reaction is completed, after subsequent processes such as purification, high-purity 5-cyano-2-fluorotrifluorotoluene -α,α,α, 4-tetrafluoro-m-toluenitrile is obtained. In this way, only excellent products can be obtained.
Chemical Reactions & Modifications
Taste the industry of chemical industry, the way of research is to "chemical feedback and modification". Today, there are 5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-toluonitrile, which is quite meaningful in our research.
The process of chemical feedback is like a microscopic change. Elements such as dancers interact, collide and blend according to specific laws, resulting in this unique structure. However, this feedback is not achieved overnight. Temperature, pressure, and catalyst are all key. A millimeter difference can lead to very different results.
As for modification, it is a wonderful way to optimize its properties. By means of chemistry, adjust the arrangement of its molecules, change the characteristics of its bonds, and make its performance outstanding. It can increase its stability or change its solubility, which is of great benefit in practical applications. After repeated investigation, we strive to find the best way to make this chemical in the field of industry and scientific research, and play the best effect, so as to become our ambition of research.
Synonyms & Product Names
5-Cyano-2-fluorotrifluorotoluene 、α,α,α, 4-tetrafluoro-m-methylbenzonitrile, both of which are important chemicals. In my chemical research, such compounds are often explored.
5-cyano-2-fluorotrifluorotoluene, also known as [enumerate possible aliases], is widely used in the field of organic synthesis and can be used as a key intermediate to help synthesize a variety of high value-added products. α, α, α, 4-tetrafluoro-m-methyl benzonitrile, also known as [enumerate possible aliases], has unique roles in materials science, drug development and other fields.
Although the names of the two are different, there may be similarities in chemical properties and reactivity. Studying its isomers and trade names can further investigate its characteristics and applications. After unremitting research, I hope to have more breakthroughs and discoveries in related fields.
Safety & Operational Standards
Safety and Handling Specifications for 5-Cyano-2-fluorotrifluorotoluene and α, α, α, 4-tetrafluoro-m-toluenitrile
Fu 5-cyano-2-fluoro-trifluorotoluene and α, α, 4-tetrafluoro-m-toluenitrile are all substances involved in chemical research. Safety and handling practices are of paramount importance during its experiments and applications.
First word safety. Both may have certain chemical activity and potential hazards. When storing, it should be stored in a cool, dry and well ventilated place away from fire and heat sources. It should be stored separately from oxidizing agents, reducing agents, acids, alkalis, etc., and should not be mixed to prevent dangerous chemical reactions. When taking it, the experimenter must wear appropriate protective equipment, such as laboratory clothes, gloves, and protective glasses to prevent the substance from contacting the skin and eyes and causing damage. In case of accidental contact, rinse with plenty of water immediately, and seek medical treatment as appropriate.
Times and operating specifications. In the experimental operation room, ensure that the ventilation equipment is working normally to eliminate possible harmful gases. The operation process needs to be strictly standardized and carried out according to the established experimental procedures. When measuring the substance, be sure to use an accurate measuring tool to ensure accurate dosage. During the reaction process, pay close attention to the reaction conditions, such as temperature, pressure, reaction time, etc., and precisely control it to prevent the reaction from getting out of control. If the heating operation is involved, a suitable heating method should be selected, and someone should be on duty. After the experiment is completed, the remaining substances should be properly disposed of according to regulations and should not be discarded at will to avoid polluting the environment.
In short, in the research and application of 5-cyano-2-fluorotrifluorotoluene and α, α, α, 4-tetrafluoro-m-toluenitrile, strict adherence to safety and operating standards can ensure the smooth operation of the experiment, the safety of personnel, and the cleanliness of the environment.
Application Area
5-Cyano-2-fluorotrifluorotoluene and α, α, α, 4-tetrafluoro-m-toluonitrile are widely used in various chemical fields. In the process of pharmaceutical creation, it can be a key intermediate, help the research and development of new drugs, fight various diseases, and benefit people's livelihood. In the way of material preparation, it can give material-specific properties, such as enhancing its stability and weather resistance, making the material suitable for a variety of harsh scenarios.
At present, the industrial evolution is continuous, and the demand for it is increasing. However, the synthesis method needs to be refined, improve yield, reduce energy consumption, and weaken pollution, in order to achieve the purpose of green sustainability. And exploring new application fields and expanding their functional boundaries is also a top priority. Our chemical researchers should study diligently to make these two things bloom in the application field and promote the industry to a new course.
Research & Development
I have been dedicated to the research of 5-cyano-2-fluorotrifluorotoluene and α, α, α, 4-tetrafluoro-m-toluonitrile for a long time. The two have different chemical properties, but they are of great value for industrial use and reaction mechanism exploration.
At the beginning, its structure was carefully investigated to explain the reason for its chemical properties. After repeated experiments, it was observed that its reaction under different conditions, recorded changes, and analyzed its laws. Then think about improvement methods to improve its yield and optimize quality.
When researching, we also think about its future development. These two products may be used in the synthesis of new materials or emerge in the field of medicine. Therefore, we should continue to study and explore relentlessly, hoping to make new discoveries and contribute to the development of the chemical field, so that it can better serve the world.
Toxicity Research
The study of poisons is related to the health of people's livelihood and cannot be ignored. Today, there is 5-cyano-2-fluorotrifluorotoluene α, α, α, 4-tetrafluoro-m-toluonitrile. The study of its toxicity is of paramount importance.
Examine this substance in detail, in the experiment, observe its response to various substances, and observe the signs of its entry into the body. Or you can borrow the genus of white rats and feed them an appropriate amount to observe changes in their behavior and physiology. If you see malaise, loss of diet, or even damage to organs, it can be a sign of toxicity.
Furthermore, consider its volatilization. In the air, if a person smells it, does it cause dizziness and poor breathing? And it dissolves into water, how do aquatic things be affected by it? This is the priority of toxicity research. Only by exploring in detail and understanding the depth of its toxicity can we determine a protective policy to protect everyone from it.
Future Prospects
Looking at this "5-cyano-2-fluorotrifluorotoluene α,α,α, 4-tetrafluoro-m-methylbenzonitrile" now, although it is in a small state, its future prospects are limitless. This compound has a unique structure, or it can shine in the field of medicine, finding a new way to cure various diseases; or it can be used in materials science to create materials with extraordinary properties. Those of us who are scientific researchers should explore its mysteries and tap its potential with diligence and diligence. With time, it will surely be able to shine brightly on the scientific stage of the future, contribute to the well-being of mankind, achieve an unparalleled career, draw a beautiful blueprint, lead the trend of science and technology, and move towards a bright future.
Frequently Asked Questions
What are the main uses of 5-Cyano-2-fluorotrifluorotoluene (5-Cyano-2-Fluorobenzotrifluoride) and α, α, α, 4-tetrafluoro-m-toluonitrile (Alpha, Alpha, Alpha, 4-Tetrafluoro-M-Tolunitrile)?
5-Cyano-2-fluorotrifluorotoluene (5-Cyano-2-Fluorobenzotrifluoride) and α, α, α, 4-tetrafluoro-m-toluonitrile (Alpha, Alpha, Alpha, 4-Tetrafluoro-M-Tolunitrile) are fluorinated organic compounds, which are widely used in organic synthesis, pharmaceutical chemistry, materials science and other fields.
In the field of organic synthesis, both are key synthetic intermediates. The cyano group, fluorine atom and trifluoromethyl group of 5-cyano-2-fluoro-trifluorotoluene are unique and active, and can participate in many classical reactions, such as nucleophilic substitution reaction, the cyano group can be replaced with nucleophilic reagents, and different functional groups are introduced to expand the molecular structure ;α,α,α, The tetrafluoromethyl group of 4-tetrafluoro-m-toluenitrile and the cyanyl group can also be converted into carboxyl groups through various reactions, such as hydrolysis reaction, or converted into amino groups through reduction reaction, etc., to synthesize complex organic compounds, providing various paths for the creation of new compounds.
In the field of pharmaceutical chemistry, due to its fluorine-containing properties, it can significantly affect the physical and chemical properties of drug The introduction of fluorine atoms can enhance the fat solubility of molecules, which is conducive to the passage of drugs through biofilms and improve bioavailability; it can also enhance the stability of molecules, resist the degradation of metabolic enzymes, and prolong the action time of drugs in the body. These two can be used as structural fragments of lead compounds. After structural modification and optimization, new specific drugs can be developed, such as anti-cancer, antiviral, and antibacterial drugs.
In terms of materials science, the special properties of fluorinated compounds can be used to prepare high-performance materials. 5-cyano-2-fluorotrifluorotoluene and α, α, α, 4-tetrafluoro-m-toluonitrile can be used as raw materials to participate in the polymerization reaction to prepare fluoropolymers. This type of polymer has excellent weather resistance, chemical corrosion resistance, and low surface energy, and can be used to make special coatings, high-performance plastics, optical materials, etc. It is widely used in aerospace, electronics, automotive, and other industries.
What are the physical properties of 5-Cyano-2-fluorotrifluorotoluene (5-Cyano-2-Fluorobenzotrifluoride) and α, α, α, 4-tetrafluoro-m-toluonitrile (Alpha, Alpha, Alpha, 4-Tetrafluoro-M-Tolunitrile)
5-Cyano-2-fluorotrifluorotoluene (5-Cyano-2-Fluorobenzotrifluoride) and α, α, α, 4-tetrafluoro-m-toluenitrile (Alpha, Alpha, Alpha, 4-Tetrafluoro-M-Tolunitrile) are fluorinated organic compounds with important applications in the chemical industry. Their physical properties are as follows:
** 1. ** Appearance and characteristics **: At room temperature, it is mostly colorless to light yellow transparent liquid, visually clear and pure, without obvious impurities and precipitation, and often shows such characteristics in chemical production observation.
2. ** Odor **: emits an irritating odor, and smells a special chemical smell. This smell can be used as a preliminary basis for identification in operation and use scenarios to remind personnel to take good protection.
3. ** Boiling point **: The boiling point is in a specific temperature range, about 140-145 ° C. The boiling point determines its behavior in processes such as heating separation. Under suitable temperature conditions, gas-liquid conversion can be realized.
4. ** Melting point **: The melting point is relatively low, about - 20 ° C, which means that it exists stably in a liquid state at room temperature, and it is possible to solidify in a low temperature environment. The storage and transportation temperature requirements are different.
5. ** Solubility **: It is difficult to dissolve in water. Due to the influence of fluorine atoms and cyanyl groups in the molecular structure, the polarity difference with water is large, but it is easily soluble in common organic solvents such as ethanol, ether, dichloromethane, etc. It is of great significance in the construction of organic synthesis reaction systems.
6. ** Density **: The density is greater than that of water, about 1.45 - 1.50 g/cm ³. In stratification experiments or mixed systems, it will be in the lower layer. This characteristic can be used in the separation and purification process.
** 、α,α,α, 4-tetrafluoro-m-toluene nitrile **
1. ** Appearance and properties **: Usually colorless to slightly yellow liquid, similar in appearance to 5-cyano-2-fluorotrifluorotoluene, transparent, this state is presented in production and experimental observations.
2. ** Odor **: Also has an irritating odor, similar to the odor of 5-cyano-2-fluorotrifluorotoluene. Protective measures should be taken during operation and contact to avoid inhalation.
3. ** Boiling point **: The boiling point is about 150 - 155 ° C, slightly higher than 5-cyano-2-fluorotrifluorotoluene. The separation of the two can be achieved based on the difference in boiling point in the separation process such as distillation.
4. ** Melting point **: The melting point is about -30 ° C, which is lower than 5-cyano-2-fluorotrifluorotoluene. It has better low temperature stability and stronger tolerance to low temperature storage and transportation.
5. ** Solubility **: It has very little solubility in water and belongs to hydrophobic substances. It has good solubility in organic solvents such as acetone and ethyl acetate, providing a solubility basis for organic reactions.
6. ** Density **: The density is about 1.35 to 1.40 g/cm ³, which is larger than water but less than 5-cyano-2-fluorotrifluorotoluene. It shows different positions in the stratification of the mixed system and is a reference for separation and identification.
What are the chemical properties of 5-Cyano-2-fluorotrifluorotoluene (5-Cyano-2-Fluorobenzotrifluoride) and α, α, α, 4-tetrafluoro-m-toluonitrile (Alpha, Alpha, Alpha, 4-Tetrafluoro-M-Tolunitrile)
5-Cyano-2-fluorotrifluorotoluene (5-Cyano-2-Fluorobenzotrifluoride) and α, α, α, 4-tetrafluoro-m-toluenitrile (Alpha, Alpha, Alpha, 4-Tetrafluoro-M-Tolunitrile) are fluorine-containing organic compounds, and their chemical properties are interesting. Let me explain in detail for you.
5-cyano-2-fluorotrifluorotoluene, the cyano group (-CN) in the molecule gives it a certain reactivity. Cyanyl groups can participate in a variety of reactions, such as hydrolysis reactions. Under appropriate conditions, cyanyl groups can be converted into carboxyl groups (-COOH), thereby generating corresponding carboxylic acid derivatives. This reaction is often used in organic synthesis to construct compounds containing carboxyl groups, laying the foundation for further functional group conversion. The introduction of fluorine atoms not only enhances the stability of the molecule, but also affects the electron cloud distribution of the molecule due to its high electronegativity, which decreases the electron cloud density of the carbon atoms connected to it, thereby affecting the nucleophilic substitution reaction activity of the compound. Trifluoromethyl (-CF) has strong electron-withdrawing properties, which can significantly change the physical and chemical properties of molecules, such as improving the lipid solubility of compounds, affecting their solubility in different solvents, and can be used as a stable functional group in some reactions, affecting the selectivity of the reaction.
α,α,α, 4-tetrafluoro-m-toluonitrile, which also contains a cyano group, has the general reaction characteristics of cyano groups. The existence of four fluorine atoms greatly changes the electronic structure and spatial configuration of the molecule. The strong electron-withdrawing effect of fluorine atoms reduces the electron cloud density on the benzene ring, making it relatively difficult for electrophilic substitution reactions to occur. On the contrary, nucleophilic substitution reactions may be easier to proceed. Due to the steric hindrance of multiple fluorine atoms, the spatial structure of molecules is relatively special, which affects the stereochemistry of the reactions they participate in. In addition, fluorine atoms at the α position can undergo elimination reactions under appropriate conditions due to their special positions, providing a unique reaction path for organic synthesis.
Both exhibit different chemical properties from traditional organic compounds due to the existence of fluorine atoms, and have important application potential in organic synthesis, pharmaceutical chemistry and other fields. They can be used to design and synthesize new compounds with special properties.
What is the method for producing 5-Cyano-2-fluorotrifluorotoluene (5-Cyano-2-Fluorobenzotrifluoride) and α, α, α, 4-tetrafluoro-m-toluenitrile (Alpha, Alpha, Alpha, 4-Tetrafluoro-M-Tolunitrile)?
5-Cyano-2-fluorotrifluorotoluene (5-Cyano-2-Fluorobenzotrifluoride) and α, α, α, 4-tetrafluoro-m-toluenitrile (Alpha, Alpha, Alpha, 4-Tetrafluoro-M-Tolunitrile) are both organic compounds, and their preparation methods are different due to differences in processes, raw materials, etc. The following is a brief description of common production methods:
First, 5-cyano-2-fluorotrifluorotoluene, often with 2-fluoro-5-nitrotrifluorotoluene as the starting material. This raw material is heated and stirred with cuprous cyanide in a suitable organic solvent, such as N, N-dimethylformamide (DMF). The cyano group in cuprous cyanide will replace the nitro group to obtain the target product. This reaction requires strict control of temperature and reaction time. If the temperature is too high or the time is too long, side reactions are prone to occur. In addition, 2-fluoro-5-nitrotrifluorotoluene can also be reduced to 2-fluoro-5-aminotrifluorotoluene first, and then prepared by diazotization, cyano substitution and other steps, but this route step is slightly complicated.
Let's talk about α, α, α, 4-tetrafluoro-m-toluenitrile, usually m-xylene as the starting material. M-xylene is first side-chain chlorinated with chlorine under the action of light or initiator to obtain trichloro-m-xylene. Then ,α,α,α - trichloro-m-xylene and anhydrous hydrogen fluoride under the action of catalysts such as antimony pentachloride, the fluorination reaction occurs, so that the chlorine atom is replaced by the fluorine atom to form α,α,α - trifluoro-m-toluene. Finally ,α,α,α - trifluoro-m-toluene, ammonia and oxygen in the presence of a catalyst, through the ammonia oxidation reaction, the methyl group is converted into a cyanyl group to obtain α, α, α, 4-tetrafluoro-m-toluenitrile. In this process, the reaction conditions at each step need to be carefully controlled. The amount of chlorine and light intensity during chlorination, the amount of hydrofluoric acid and the activity of the catalyst during fluorination, the ratio of ammonia to oxygen and the reaction temperature during ammonia oxidation all have important effects on the yield and purity of the product.
What is the market price range for 5-Cyano-2-fluorotoluene (5-Cyano-2-Fluorobenzotrifluoride) and α, α, α, 4-tetrafluoro-m-toluenitrile (Alpha, Alpha, Alpha, 4-Tetrafluoro-M-Tolunitrile)?
The price of 5-cyano-2-fluorotrifluorotoluene (5-Cyano-2-Fluorobenzotrifluoride) and α, α, α, 4-tetrafluoro-m-toluonitrile (Alpha, Alpha, Alpha, 4-Tetrafluoro-M-Tolunitrile) in the market is also a question.
The market price of such compounds often varies with time, place, quality, quantity and supply and demand, and it is difficult to determine. Looking at the traces of past transactions, the price of such compounds fluctuates frequently.
5-Cyano-2-fluoro-trifluorotoluene, if the amount is small, or tens to hundreds of yuan per gram, buy in bulk, the gram price may be slightly reduced. The method of covering its production needs to be fine, the raw materials and processes are related to the cost, so the price is this much.
α,α,α, 4-tetrafluoro-m-toluenitrile is also the same, and the retail price per gram may be tens to hundreds of yuan. If the purchase quantity is large, the manufacturer may reduce the price per gram by a few yuan to tens of yuan in order to promote the transaction.
And the market situation is changing rapidly, and the price of chemical raw materials also changes with the price of basic materials such as crude oil, policy regulation, and environmental protection requirements. In order to know the real-time price, when consulting chemical raw material suppliers and trading platforms, you can know the current price range.