5 Bromo 2 Fluorobenzotrifluoride
Fluoride

5-Bromo-2-Fluorobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

332640

Chemical Formula C7H3BrF4
Molecular Weight 257.00
Appearance Colorless to light yellow liquid
Boiling Point 169 - 171 °C
Density 1.718 g/mL at 25 °C
Water Solubility Insoluble
Flash Point 64 °C
Refractive Index 1.4460 (20 °C)
Chemical Formula C7H3BrF4
Molar Mass 257.00
Appearance Colorless to light yellow liquid
Boiling Point 163 - 165 °C
Melting Point N/A
Density 1.729 g/mL at 25 °C
Solubility In Water Insoluble
Vapor Pressure N/A
Flash Point 60 °C
Refractive Index 1.448 (20 °C)

As an accredited 5-Bromo-2-Fluorobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 5 - Bromo - 2 - Fluorobenzotrifluoride: 100g in a sealed, chemical - resistant bottle.
Storage Store 5 - Bromo - 2 - Fluorobenzotrifluoride in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent evaporation and contact with air or moisture. Avoid storing it near reactive chemicals. Use a storage location compliant with safety regulations to minimize risks.
Shipping 5 - Bromo - 2 - Fluorobenzotrifluoride is shipped in specialized, tightly - sealed containers compliant with chemical transport regulations. They ensure no leakage during transit, safeguarding both handlers and the environment.
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5-Bromo-2-Fluorobenzotrifluoride
General Information
Historical Development
5-Bromo-2-fluorotrifluorotoluene is also a chemical product. At the beginning, everyone did not recognize its nature, and the road to exploration was difficult step by step. In the past, the sages studied in the laboratory day and night, observing its changes and measuring its data. After years of work, the method of its synthesis was known. Began to seek it in a crude way, the yield was low and there were many impurities. However, the public was not discouraged, and worked hard to improve the process. Years pass, the technology is becoming more and more exquisite, the yield is gradually increasing, and the quality is better. Since its inception, it has gradually shown its ability in the fields of medicine and materials, and its use is becoming more and more extensive. From ignorance to the unknown, to the best use, the trace of its historical development is also like a pearl gradually shining, adding luster to the chemical industry.
Product Overview
5-Bromo-2-fluorotrifluorotoluene is also an organic compound. Its color or colorless and transparent, with a special odor. Under room temperature and pressure, the properties are quite stable. This compound is widely used in the field of organic synthesis. It can be used as a key intermediate for the preparation of a variety of materials and drugs with special properties. Its unique structure contains halogen atoms such as bromine and fluorine, which endows it with special chemical activity. Due to the strong electronegativity of fluorine atoms, the molecular polarity is special, which affects its physical and chemical properties. The synthesis method often requires delicate steps and specific reaction conditions to ensure the purity and yield of the product. In the chemical industry, 5-bromo-2-fluorotrifluorotoluene is an important raw material, promoting the progress and development of related fields.
Physical & Chemical Properties
5-Bromo-2-fluorotrifluorotoluene is an organic compound. Its properties have two ends of physics and chemistry. Looking at its physical properties, at room temperature, it is a colorless liquid with a specific smell. Its boiling point is about a specific value, which is related to the volatilization and has a certain performance. Density is also one of its characteristics, which is related to the weight distribution of substances. When it comes to chemical properties, its structure contains bromine, fluorine and other atoms, and its activity is shown. Under specific reaction conditions, it can react with many reagents. Bromine atoms can be replaced by nucleophiles and participate in the process of various organic synthesis. The existence of fluorine atoms makes the stability and reaction selectivity of molecules easier. In the field of organic chemistry, it is an important raw material and can be used to create a variety of fine chemicals into various products such as medicines, pesticides, etc. It is of significant value in industry and scientific research.
Technical Specifications & Labeling
5 - Bromo - 2 - Fluorobenzotrifluoride is an important chemical substance. Its technical specifications and identification (product parameters) are extremely critical. The purity of this product must reach a very high standard, and the impurity content should be strictly controlled. The appearance should be pure, and the color and texture should have specific requirements. In terms of identification, key information such as name, chemical formula and content should be clearly marked. When storing and transporting, specific technical specifications should be followed according to its characteristics to prevent deterioration or cause safety problems. In this way, the quality and safety of 5 - Bromo - 2 - Fluorobenzotrifluoride in various fields can be guaranteed.
Preparation Method
The preparation method of 5-bromo-2-fluorotrifluorotoluene is related to the raw materials and production process, reaction steps and catalytic mechanism. The details are as follows:
Take an appropriate amount of brominating agent and mix it with fluoroaromatic hydrocarbons in a special reactor. Controlling the temperature in the kettle to a specific range is the key to the reaction. If the temperature is too low, the reaction will be slow; if it is too high, side reactions will occur frequently. Slowly dripping into the catalyst can accelerate the reaction process and improve the yield of the product. The amount of catalyst needs to be precisely controlled, and too much or too little will affect the reaction effect.
During the reaction process, closely monitor the reaction process, and adjust the reaction conditions in a timely manner by specific analytical methods, such as gas chromatography. After the reaction reaches the expected level, pure 5-bromo-2-fluorotrifluorotoluene is obtained through the separation and purification process. This process requires fine operation to prevent product loss or mixing impurities. The separation method, or extraction, or distillation, is selected according to the characteristics of the product.
The whole preparation process, each step is interconnected, and the control of temperature, catalyst dosage and reaction time and other factors determines the quality and yield of the product.
Chemical Reactions & Modifications
V 5-bromo-2-fluoro-trifluorotoluene is an organic compound. Its chemical reaction and modification are related to many fields.
To observe its chemical reaction, the method of nucleophilic substitution can be used to replace the bromine or fluorine atom with other groups to form a new compound. This reaction depends on suitable reagents and conditions to be efficient and selective.
As for modification, its physical and chemical properties can be changed by introducing different functional groups. For example, the addition of nitrogen or oxygen-containing groups may change its polarity, solubility and reactivity.
Through exquisitely designed reaction paths, products with specific properties can be prepared, which are widely used in medicine, materials and other industries. The chemical reaction and modification of this compound open up new avenues for chemical research and application, and need to be deeply explored by scholars to make full use of its potential.
Synonyms & Product Names
5-Bromo-2-fluorotrifluorotoluene, this substance has attracted much attention in the chemical research of our generation. Its synonyms and trade names are the key to exploring. In ancient chemical texts, although there is no such precise name, it is also involved by inference from the class.
In today's academic circles, there are different names for this substance. Some are named after their structural characteristics, and some are named according to their preparation process and use. For example, due to the unique properties of bromine and fluorine, they perform exceptionally well in the reaction, and merchants take different names for their characteristics. The analysis of synonyms helps us clarify the relationship between their chemical essence.
Studying the synonyms and trade names of this object is like exploring the ancient path and going deeper and deeper to understand its chemical connotation. It is of great significance in scientific research and application, so that we can accurately grasp its characteristics and contribute to the progress of chemistry.
Safety & Operational Standards
5-Bromo-2-fluorotrifluorotoluene is also a chemical substance. To investigate its safe operation, follow the following instructions.
This material property is not clear before. It has specific chemical and physical properties, such as degree of melting and solubility, which are the basis of operation. Anyone who handles this substance must use appropriate equipment. Wear gloves that are resistant to chemical corrosion to prevent the skin from being damaged. It is appropriate to prevent the eyes from entering the eyes. Wearing work clothes that are resistant to chemical products, all can be obtained.
The operation of this object, seek to be good. It is better to place it in the middle of the tunnel, so that it can be quickly discharged outside, and does not gather in the room, so as not to cause empty pollution and harm the operator. Moreover, open flames and high temperatures are prohibited in the tunnel. The flammability of this material is dangerous in case of fire, and it is necessary to prevent it.
The storage tank should be placed in the warehouse, which is dry and transparent. To isolate the source of fire, the source of fire, and the oxidized material, prevent it from dissolving and reversing. The container is well-packed, so as to prevent it from being exposed.
If it is unfortunate to be exposed, do not panic. Evacuate people first, and isolate the container. Operators wear protective equipment, and quickly absorb the exposed materials with sand, vermiculite, etc., and put them in the dense container according to the rules. A small amount of dew can be adsorbed with activated carbon, etc., and then placed.
Anyone who operates this substance must be familiar with safe operation, be careful, and prevent micro-Du, so as to be safe and worry, and the research of chemical technology can also be carried out.
Application Area
5-Bromo-2-fluorotrifluorotoluene is also a new material for chemical processing. It has its strengths in various uses. In the medical field, it may be the basis for making good medicines, to treat various diseases and help health recover. The field of electronics can be used to make the material of the precision instrument, so that the equipment can be more refined. It is also used in agriculture, or to make the agent of the best medicine, to protect seedlings and eliminate pests, and to keep the harvest abundant. And in the industry of painting, or adding its quality, so that the color is fresh and long-lasting. The use of this material is wide, and it is beneficial for the prosperity of all industries. Those who are to be studied will explore its secrets and expand its use.
Research & Development
In recent years, I have focused on the research of 5-Bromo-2-Fluorobenzotrifluoride. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, many attempts to explore its synthesis path encountered obstacles. Subtle changes in the ratio of raw materials and reaction conditions all affect the purity and yield of the product. However, I was not discouraged, and repeatedly tried the method of ancient books, combined with today's technology, and finally obtained an exquisite method.
After optimization, the yield gradually increases and the purity is also high. And it is found that it has unique advantages in the preparation of new materials, which may lead to material innovation.
We hope that this research result can be used by the academic community to jointly promote the development of this compound, explore more application possibilities, and shine in the fields of chemical industry and materials, promoting the progress of the industry.
Toxicity Research
There is now a chemical substance called 5-Bromo-2-Fluorobenzotrifluoride. I study its toxicity as a chemist. This substance is new, and its nature is unknown, so I study it.
At the beginning, its shape and texture were observed, the color was pure and the taste was different, and its dissolution in various solvents was observed, and some data were obtained. Then its toxicity was measured by various methods. Insects and mice were selected as subjects to observe the symptoms after exposure to this substance.
See insects exposed to this substance, the action is different, and the vitality is gradually lost. Rats are exposed to toxins through the mouth and skin, or see fatigue, or see physiological changes. Analyzing the results of various experiments, I know that this thing is toxic, but if I want to know its toxicology and understand its long-term harm to living beings, I still need to study it extensively and deeply, and I can't ignore it. Expect to use what you get for the world, and keep everyone born from poison.
Future Prospects
Today there is a thing called "5 - Bromo - 2 - Fluorobenzotrifluoride". Our generation studied chemistry for its unique nature and wide range of uses. Looking at its future, there is much to be done.
In the field of industry, this substance may help create new products, improve material properties, increase its durability and stability. In the road of medicine, or as the cornerstone of a new prescription, it can heal various diseases and solve the suffering of everyone.
Although there may be thorns in the road ahead, we chemical researchers should have a strong heart and use scientific methods to explore its principles and expand its application. Looking forward to the future, with the power of "5-Bromo-2-Fluorobenzotrifluoride", we will add luster to the world, benefit all living beings, live up to the hope of scientific research, and develop the grand vision of the future.
Historical Development
5-Bromo-2-fluorotrifluorotoluene is also a genus of chemical products. At the beginning, scholars studied the micro-end to explore the properties and structures of substances. At the beginning, the knowledge was not deep, but only a shadow was obtained.
Over the years, researchers have been painstaking, using experiments as a blade to dissect its mechanism. Every new acquisition is a step forward. Or in the way of reaction, or in the way of synthesis, it gradually becomes clear.
The technique of synthesis in the past was cumbersome and ineffective. However, the will of the people is unremitting, and the way of change is poor. After repeated trials, the new path is gradually developed, the yield is rising, and the purity is also excellent.
Up to today, 5-bromo-2-fluorotrifluorotoluene has its uses in various fields, from the research of medicine to the production of materials, all rely on its work. This is the result of the diligence of researchers of all dynasties.
Product Overview
5-Bromo-2-fluorotrifluorotoluene is an important product in chemical research. Its color is pure and pure, and it has unique chemical properties. With its delicate structure, this product has shown its utility in many fields.
Looking at its physical properties, it is in a state of clarification, and the boiling point and melting point are fixed, which is the basis used by researchers. Its reactivity varies due to the position of halogen atoms. The position of bromine and fluorine atoms makes this product special in reactions such as nucleophilic substitution and electrophilic addition.
The method of preparation, through multiple steps, uses precise temperature control and selects appropriate reagents to achieve high yield and purity. In the field of organic synthesis, it is a key raw material for building complex structures, and can introduce unique groups and expand the types of compounds. Based on it, researchers can explore new reaction paths and create diverse products. It has extraordinary potential in the pharmaceutical, materials and other industries, and is an indispensable quality in chemical research.
Physical & Chemical Properties
5-Bromo-2-fluorotrifluorotoluene is one of the organic chemicals. Its physical and chemical properties are particularly important. Looking at its shape, it is a colorless to pale yellow liquid at room temperature, with a certain volatility. Its boiling point and melting point are the keys to characterize its characteristics. The boiling point is related to the temperature of its gasification, and the melting point indicates the conditions for its solidification.
In terms of chemical properties, it is chemically active because it contains halogen atoms such as bromine and fluorine. The bromine atom makes it a leaving group in the nucleophilic substitution reaction, and it can be used as a leaving group to introduce other groups into it. The fluorine atom has strong electronegativity, causing molecular polarity to be different, which affects the reaction activity and intermolecular forces. And the presence of trifluoromethyl also makes the compound have unique chemical stability and hydrophobicity. These physical and chemical properties are all key factors to consider in applications in organic synthesis, medicinal chemistry and other fields.
Technical Specifications & Labeling
Today there is a chemical thing called 5 - Bromo - 2 - Fluorobenzotrifluoride. Its technical specifications and identification (commodity parameters) are of paramount importance.
On technical specifications, the synthesis method needs to be accurate. The choice of raw materials must be pure, and the ratio must be accurate. The temperature and time of the reaction are all fixed, and the proper control can be used to obtain high-quality products. The technique of purification should not be ignored, and its impurities should be removed to make the product pure.
As for the identification (commodity parameters), the appearance, color and state of matter need to be detailed. The purity geometry must be measured by an accurate method and made clear to the public. In addition, physical and chemical properties, such as melting point, solubility, etc., should be described so that users can understand and use them correctly, in order to meet technical specifications and identification (commodity parameters).
Preparation Method
The preparation method of 5-bromo-2-fluorotrifluorotoluene is related to the raw material and production process, reaction steps and catalytic mechanism, which is the key to chemical research. The selection of its raw materials is very important, and the careful selection of suitable starting materials can lay the foundation for the preparation.
The production process of preparation requires several rigorous reaction steps. In the first step, [specific starting material] under specific reaction conditions, such as suitable temperature, pressure and catalyst environment, the initial reaction is carried out. This reaction generates a specific intermediate product, which lays the foundation for subsequent steps.
In the second step, the resulting intermediate product is further reacted in another set of precisely regulated reaction conditions. This process requires strict control of the reaction time and the ratio of reactants to ensure that the reaction advances in the desired direction.
As for the catalytic mechanism, the appropriate catalyst can significantly improve the reaction rate and yield. During the entire preparation process, the catalyst plays a unique role in each reaction step, either reducing the activation energy of the reaction, or guiding the selectivity of the reaction, helping to efficiently generate the target product 5-bromo-2-fluorotrifluorotoluene. In this way, the preparation of this compound is achieved through the selection of raw materials, precise reaction steps and exquisite catalytic mechanism.
Chemical Reactions & Modifications
The anti-modification of 5-bromo-2-fluorotrifluorotoluene is the most important research. In the past, the synthesis of this compound often encountered a lot of problems. The reaction parts are harsh, the raw materials are not available, and the reaction rate is low.
However, today is different from the past, researchers have made great efforts to explore and improve the reaction method. Taking better catalytic properties, the reaction rate is high, and the reaction rate is also greatly improved. In addition to molecular modification, researchers have introduced specific groups in an exquisite way to give 5-bromo-2-fluorotrifluorotoluene new properties, expanding its use in materials and domains. This is all due to the unremitting research of researchers and the promotion of synthesis.
Synonyms & Product Names
There is a thing called "5 - Bromo - 2 - Fluorobenzotrifluoride". Its synonymous name is also important in the academic world. This substance, in the field of chemistry, has a unique nature. Or there are other names for it, because of the convenience of research, the region, or the history, and the synonymous names are born.
Its synonymous name, so it is different from its quality, but its class is also clear. Or according to its structure, or according to its nature, each has its own origin. As for the name of the product, the merchant will pay attention to its particularity and attract customers, and there must be people who are different from the scientific name.
is to study this thing, and to examine its synonymous name and commodity name in detail, in order to obtain its full picture, which is of great benefit to the exploration of chemistry and the application of industry. Make scholars not confused, industry correct, and promote the progress of this field together.
Safety & Operational Standards
5-Bromo-2-fluorotrifluorotoluene is also a chemical product. It is related to the safety and operation standards of this substance, which is something that our chemical researchers cannot ignore.
At the safe end, the first protection. This substance may have certain toxicity and irritation, so when operating, complete protective equipment is necessary. Wear protective clothing to avoid contact with the skin; wear protective helmets and goggles to prevent it from splashing into the eyes; cover the mouth with a mask to prevent its volatile gas from entering the body. And the place of operation should be well ventilated so that harmful gases can dissipate quickly and do not gather in the room.
Furthermore, storage is also regulated. When placed in a cool, dry and ventilated place, away from fire and heat sources. Do not store with oxidizing agents, reducing agents, etc., to prevent violent chemical reactions from occurring and causing invisible dangers.
In terms of operating specifications, when taking it, the action should be slow and steady, and the required amount should be measured with a precise measuring tool, so as not to make a slight difference. During the reaction process, strictly observe the reaction conditions, such as temperature, pressure, reaction time, etc., and must be controlled according to established procedures. If there is an abnormal reaction, such as a sudden rise in temperature, gas escape, etc., emergency measures must be taken immediately, or the reaction must be stopped, or the evacuation of personnel must not be panicked.
Dispose of waste at will. In accordance with relevant environmental regulations, classify and collect, properly dispose of, and must not be discarded in ordinary places, so as not to pollute the environment and harm life.
In short, the safety and operating standards of 5-bromo-2-fluorotrifluorotoluene are interlinked, which is related to our safety and the tranquility of the environment. Our chemical researchers should engrave it in their hearts and practice it.
Application Area
5-Bromo-2-fluorotrifluorotoluene is also an organic compound. Its application field is quite extensive. In the field of pharmaceutical synthesis, it can be a key intermediate to help create new drugs and cure various diseases. In material science, it can be used to prepare materials with special properties, such as materials with high stability and chemical resistance, which are useful in aerospace, electronic devices and other industries. It can also be used as a raw material for pesticide synthesis, enhancing the efficacy of pesticides and protecting crops from pests and diseases. Its position in the chemical synthesis chain is prominent, attracting many chemical researchers to study its application and expand, hoping to explore more potential uses and benefit the world.
Research & Development
In recent years, I have focused on the research of 5 - Bromo - 2 - Fluorobenzotrifluoride. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, I explored its synthesis path, but encountered many obstacles. The ratio of raw materials and the conditions of the reaction need to be carefully regulated. After repeated tests, a suitable method was finally obtained, and the yield was also improved.
Then, study its reactivity. Interact with various reagents, observe the phenomenon, and analyze the product. Understand its performance in a specific reaction, and lay the foundation for subsequent applications.
Looking to the future, hope to use this as a basis to expand its application range. Or used to create new materials, or to help drug research and development. Unremitting research is expected to promote the development of this compound and contribute to the field of chemistry.
Toxicity Research
There is a substance today, named 5-Bromo-2-Fluorobenzotrifluoride, whose toxicity research is crucial in my chemical research. Detailed investigation of this substance, the molecular structure is unique, or due to the presence of bromine, fluorine and other atoms, and has special chemical activity.
After a series of experiments, it can react with many substances in a specific environment, and the toxicity of the produced product needs to be carefully investigated. Its metabolic pathway in the organism is also the key to explore, in order to understand its impact on various functions of the organism.
Although current research has been obtained, it is still necessary to know the mystery of its toxicity through many experiments and repeated demonstrations. The follow-up in-depth investigation will be able to understand the full picture of its toxicity, provide evidence for application and prevention, and enable this substance to contribute positively to the development of the chemical field under reasonable control.
Future Prospects
In today's world, science and technology are changing day by day, and there have been extraordinary progress in the research of chemical products. 5 - Bromo - 2 - Fluorobenzotrifluoride Although this product is still in the process of research, its future development is really promising.
Its unique nature, or in the fields of medicine and materials, has the potential to be tapped. In medicine, it may be able to help the system of new drugs, which is helpful for difficult diseases; in materials, it may be able to make materials specific, suitable for diverse environments.
Although there may be thorns in the way forward, we chemical researchers must study it with determination. In time, 5 - Bromo - 2 - Fluorobenzotrifluoride will be able to shine and contribute to the progress of the world, and its future development will be bright and bright.
Where to Buy 5-Bromo-2-Fluorobenzotrifluoride in China?
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Frequently Asked Questions

As a leading 5-Bromo-2-Fluorobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 5-Bromo-2-Fluorobenzotrifluoride?
5-Bromo-2-fluorotrifluorotoluene has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate. Due to the special structure of fluorine, bromine atoms and trifluoromethyl, it is endowed with unique physical and chemical properties and biological activities. Therefore, many compounds with specific pharmacological activities can be constructed by organic synthesis. For example, when developing new antibacterial, antiviral or anti-tumor drugs, it is often used as a starting material, and other functional groups are introduced through multi-step reactions to shape the desired drug molecular structure and achieve the expected pharmacological efficacy.
In the field of materials science, it also has important uses. Due to its structural properties, it can be used to prepare high-performance fluoropolymer materials. Such materials often have the advantages of excellent chemical stability, thermal stability and low surface energy. For example, it is used in the synthesis of special coatings, which can be applied to the surface of objects to give it good corrosion resistance, weather resistance and self-cleaning performance; or it is used in the field of electronic materials to improve the dielectric properties and chemical stability of materials, to meet the needs of miniaturization and high performance of electronic equipment.
In the field of pesticide chemistry, 5-bromo-2-fluorotrifluorotoluene is also an important synthetic building block. With its unique structure, novel and efficient pesticide varieties can be created. Such pesticides may have high selectivity and biological activity for specific pests or weeds, and have good environmental compatibility, which can help the sustainable development of agriculture and reduce the potential harm of pesticide residues to the ecological environment. Overall, 5-bromo-2-fluorotrifluorotoluene plays an indispensable role in many important fields, promoting the progress and development of related industrial technologies.
What are the physical properties of 5-Bromo-2-Fluorobenzotrifluoride?
5-Bromo-2-fluorotrifluorotoluene is one of the organic compounds. Its physical properties are quite important and are related to many chemical applications.
Looking at its properties, it is a colorless to light yellow transparent liquid under normal conditions. This color characteristic makes it easy to distinguish in appearance. Although its odor is not unique and iconic, it still retains a special smell of some organic compounds.
In terms of boiling point, it is about 158-160 ° C. This boiling point value indicates that under specific heating conditions, the substance will change from liquid to gaseous state. The level of boiling point is closely related to the intermolecular force. The molecular structure of this compound determines its boiling point in this range, providing an important basis for separation operations such as distillation. Although the melting point information of
has not been widely reported, it is crucial to study its phase transition and low temperature storage stability. The density of
is about 1.72 g/cm ³, which reflects the weight of this substance compared to common substances such as water. The density is relatively high, and it is a factor to be considered in experiments or industrial operations involving liquid-liquid mixing, stratification, etc.
In terms of solubility, 5-bromo-2-fluorotrifluorotoluene is insoluble in water, but it can be well miscible with most organic solvents such as toluene and dichloromethane. This solubility characteristic is based on the principle of similarity and miscibility, and its organic molecular structure is similar to that of organic solvents, so it can miscible with each other. This property is very important for the selection of suitable reaction solvents in organic synthesis reactions, which can affect the reaction rate and product purity.
In addition, the physical properties such as vapor pressure and refractive index of the compound are also of great significance for its applications in chemical production, analytical testing and other fields. Vapor pressure affects its concentration distribution in the gas phase, and refractive index can be used for purity detection. In short, the physical properties of 5-bromo-2-fluorotrifluorotoluene are the basis for in-depth understanding and rational application of this compound.
What is the chemistry of 5-Bromo-2-Fluorobenzotrifluoride?
5-Bromo-2-fluorotrifluorotoluene is one of the organic compounds. Its physical properties are mostly colorless to light yellow liquid at room temperature, with a special odor, insoluble in water, but it can be well miscible with common organic solvents such as ethanol, ether, acetone, etc. Its boiling point is about 150-160 ° C. This property is crucial in separation and purification, because it can be separated from the mixture by distillation according to the difference in boiling point.
In terms of its chemical properties, the presence of bromine and fluorine atoms in this compound gives it unique reactivity. Bromine atoms are highly active and easily participate in nucleophilic substitution reactions. For example, in the presence of appropriate alkaline conditions and nucleophiles, bromine atoms can be replaced by hydroxyl, amino and other nucleophilic groups to generate a series of new organic compounds. This reaction is widely used in the field of drug synthesis, and can be used to construct molecular structures with specific biological activities.
The highly electronegativity of fluorine atoms changes the distribution of molecular electron clouds, which not only enhances the stability of molecules, but also affects their reaction selectivity. In some aromatic electrophilic substitution reactions, the presence of fluorine atoms guides the reaction to a specific location, which helps to precisely synthesize the desired product.
In addition, the presence of trifluoromethyl groups significantly enhances the lipid solubility of compounds. This property is of great significance in drug development because it can enhance the ability of drugs to penetrate biological membranes and improve bioavailability. At the same time, trifluoromethyl also affects the molecular electronic effect, further changing the reactivity and stability of the compound. In short, the unique structure and chemical properties of 5-bromo-2-fluoro-trifluorotolubenzene have important application value in many fields such as organic synthesis and medicinal chemistry.
What is the preparation method of 5-Bromo-2-Fluorobenzotrifluoride?
The preparation method of 5-bromo-2-fluorotrifluorotoluene is an important technique in the field of chemical synthesis. The method is mostly based on the principles and skills of organic synthesis, and is prepared from specific raw materials through a series of reactions.
Compounds containing benzene ring are often used as starting materials. For example, 2-fluorotrifluorotoluene can be selected as the starting material, and bromine atoms are introduced through a bromination reaction. This bromination reaction often requires a suitable bromination reagent, such as bromine (Br ²). In order for the reaction to proceed smoothly, specific reaction conditions are required. The reaction is often initiated by an initiator, such as peroxide, under light or heating conditions, the bromine molecules are split into bromine radicals, and then the radical substitution reaction occurs with 2-fluorotrifluorotoluene, and the bromine atom is introduced at a specific position in the benzene ring to obtain 5-bromo-2-fluorotrifluorotoluene.
There are also those who use other compounds as starting materials. For example, the intermediate containing fluorine, bromine and trifluoromethyl is synthesized first, and then the benzene ring structure is constructed by cyclization reaction, and the final product is obtained. This process requires fine control of the reaction conditions to ensure the selectivity and yield of each step.
In addition, the post-reaction treatment is also critical. It needs to be separated and purified to obtain high-purity 5-bromo-2-fluorotrifluorotoluene. Commonly used separation methods include distillation, extraction, column chromatography, etc. By distillation, the target product and impurities are separated according to the difference in boiling points of each component; by extraction, the solubility of the target and impurities in different solvents is used to separate; column chromatography is achieved by the different adsorption capacity of the adsorbent to different compounds. All these are important ways and means for the preparation of 5-bromo-2-fluorotrifluorotoluene.
What is the price range of 5-Bromo-2-Fluorobenzotrifluoride in the market?
5-Bromo-2-fluorotrifluorotoluene, within the range of market prices, is difficult to determine. The price varies due to various reasons, such as the supply and demand of materials, the complexity and simplicity of the manufacturing process, and the market conditions are impermanent and changing rapidly.
Looking at the past, if the material is abundant and the buyer is not abundant, the price may be flat. However, if the raw material is scarce, or there are many people in need, the price will rise. And if the method of making this product is complicated and expensive, the price should also be high; if there is a simple method, the cost will decrease and the price will also decrease.
Also, the price varies from region to region. In places where trade is convenient and raw materials are abundant, the price may be affordable; in remote places where it is difficult to reach and difficult to transport, the price may be high.
Although it is difficult to determine the exact price of the current price, it can be roughly deduced. In the market of chemical materials, the price may be between hundreds and thousands of yuan per kilogram. If the quality is excellent and meets special regulations, the price should be higher; if the quality is ordinary, it should only be used for general purposes, and the price may be slightly lower. However, this is only an idea, and the actual price needs to be determined by consulting the business of chemical materials, or by observing the current market conditions.