5 Amino 2 Nitrobenzotrifluoride
Fluoride
5-Amino-2-nitrobenzotrifluoride
Chemical Formula C7H5F3N2O2
Molecular Weight 206.12
Appearance Yellow to orange - red solid
Cas Number 393 - 11 - 3
Melting Point 74 - 78 °C
Boiling Point 273.7 °C at 760 mmHg
Density 1.509 g/cm³
Flash Point 119.3 °C
Solubility Insoluble in water, soluble in organic solvents like ethanol, ethyl acetate
Purity Typically available in high purity grades (e.g., 97%+)
FAQ

What are the main uses of 5-Amino-2-nitrobenzotrifluoride?

5-Amino-2-nitrotrifluorotoluene is a key intermediate in the field of organic synthesis. It has a wide range of uses and has important applications in medicine, pesticides and materials science.

In the field of medicine, it is often an important raw material for the synthesis of new drugs. Through clever chemical reactions, it can be converted into compounds with specific pharmacological activities. For example, it can participate in the construction of the core structure of some anti-tumor drugs. Through its unique chemical properties, it can help drugs achieve precise action on tumor cells, or interfere with the metabolic process of tumor cells, or affect their signal transduction pathways, thereby achieving the purpose of inhibiting tumor growth.

In the field of pesticides, 5-amino-2-nitrotrifluorotoluene also plays a key role. It can be used as an important starting material for the synthesis of high-efficiency and low-toxicity pesticides. Through rational molecular design and synthesis, pesticides that are highly targeted to specific pests or bacteria can be prepared. Its special chemical structure helps to improve the biological activity and stability of pesticides, enhance their killing effect on target organisms, and reduce the adverse effects on the environment and non-target organisms.

In the field of materials science, this compound can be used to prepare polymer materials with special properties. For example, introducing it into the structure of polymer can endow materials with excellent thermal stability, chemical stability and electrical properties. It can be applied to high-end fields such as electronic devices, aerospace, etc., to meet the strict requirements of special properties of materials in these fields.

In summary, 5-amino-2-nitrotrifluorotoluene has shown indispensable value in many important fields due to its unique chemical structure, promoting technological progress and innovation in various fields.

What are the physical properties of 5-Amino-2-nitrobenzotrifluoride?

5-Amino-2-nitrotrifluorotoluene is one of the organic compounds. Its physical properties are worth exploring.

Looking at its appearance, under room temperature and pressure, it often takes a light yellow to brown crystalline powder. This form is easy to identify and operate. Its melting point ranges from about 52 ° C to 56 ° C. The characteristics of the melting point are of great significance in the purification and identification of compounds. When the temperature rises to the melting point, the substance gradually melts from solid to liquid. This transition process is an important consideration in chemical production and laboratory operations.

On solubility, 5-amino-2-nitrotrifluorotoluene is slightly soluble in water. Due to the fact that water is a highly polar solvent, and the structure of the compound makes its polarity weak, according to the principle of "similar miscibility", it is difficult to dissolve in water. However, it is soluble in organic solvents such as ethanol, ether, and dichloromethane. The polarity of organic solvents such as ethanol is moderate, and the interaction with the compound allows it to disperse uniformly in it. In organic synthesis reactions, such solubility characteristics provide the basis for the selection of reaction media. Many reactions can only proceed smoothly under specific solvent environments. Proper solvent selection can fully participate in the reaction of 5-amino-2-nitrotrifluorotoluene.

In addition, its density is also an important physical property. Although the exact density value is slightly affected by environmental factors, it generally has a specific density range. This density characteristic has guiding value in container selection and space utilization during material storage and transportation. If the density is known, the capacity of storage equipment can be accurately planned to ensure the safe storage of materials, and the transportation space can be reasonably arranged to improve transportation efficiency.

What are 5-Amino-2-nitrobenzotrifluoride synthesis methods?

The synthesis method of 5-amino-2-nitrotrifluorotoluene, through the ages, many parties have had their own wonderful methods.

First, trifluorotoluene is used as the starting material. Under appropriate reaction conditions, shilling trifluorotoluene meets the nitrate, and through nitrification, the nitro group is cleverly connected to the benzene ring to obtain a nitro-containing trifluorotoluene derivative. Then, the derivative is reduced. This reduction method, or the technique of catalytic hydrogenation, in the presence of suitable catalysts, such as palladium carbon, is introduced with hydrogen to gradually convert the nitro group into an amino group, and then 5-amino-2-nitrotrifluorotoluene is obtained.

Second, there are also other fluorobenzene derivatives as starters. After a specific reaction step, nitro groups are introduced, and the substituents on the benzene ring are cleverly arranged. Then through subtle transformation, amino groups are added. In this process, the reaction conditions, such as temperature, pressure, reaction time, and the proportion of reactants, need to be finely regulated to make the reaction proceed smoothly and ensure the purity and yield of the product.

Third, the method of organic synthesis often evolves with the times. There may be new reagents and new reaction mechanisms. Today, chemists are also constantly exploring more efficient and green synthesis paths. Or through the development of new catalysts to make the reaction conditions milder, reduce energy consumption and waste generation; or adopt novel reaction strategies to shorten the reaction steps, improve the utilization rate of atoms, and make the synthesis process more economical and environmentally friendly. However, no matter what method, chemists need to repeatedly test and carefully optimize in order to achieve the ideal synthesis effect.

5-Amino-2-nitrobenzotrifluoride What are the precautions during storage and transportation?

5-Amino-2-nitrotrifluorotoluene is an organic compound. When storing and transporting, many things need to be paid attention to.

First, when storing, place it in a cool and ventilated warehouse. This compound is more sensitive to heat, and high temperature can easily cause it to decompose, causing danger. The temperature can be effectively controlled in a cool and ventilated place. The temperature of the warehouse should be maintained within a suitable range, and it must not be too high.

Second, be sure to keep away from fires and heat sources. Because of its certain chemical activity, open fires and hot topics are very likely to cause combustion or even explosion accidents, so fires and heat sources need to be kept at a safe distance.

Third, it should be stored separately from oxidants, acids, bases, etc., and should not be mixed. The chemical properties of 5-amino-2-nitrotrifluorotoluene determine that it may have violent chemical reactions when it comes into contact with these substances, resulting in adverse consequences.

Fourth, the container in which the substance is stored must be sealed. On the one hand, it can prevent it from evaporating into the air and polluting the environment. On the other hand, it can avoid reacting with components in the air and affecting its quality.

As for transportation, transportation vehicles should ensure good ventilation conditions. Because heat may be generated inside the vehicle during transportation, good ventilation can dissipate heat in time, reduce temperature and reduce danger.

Furthermore, when transporting, it is necessary to strictly follow the specified route, do not change the route at will, and avoid sensitive areas such as densely populated areas and traffic arteries to prevent accidents such as leaks during transportation and pose a threat to public safety.

In addition, transporters must be familiar with the properties of the compound and emergency treatment methods. In the event of an unexpected situation on the way, they can respond in a timely and appropriate manner to reduce the harm.

What is the market price of 5-Amino-2-nitrobenzotrifluoride?

5-Amino-2-nitrotrifluorotoluene, the price of this product in the market is very difficult to determine. The change in its price depends on multiple ends.

First, the price of raw materials is the main factor. To prepare this product, the price of the raw materials used fluctuates from time to time as the demand for the raw materials is obtained. If the production of raw materials changes, such as unfavorable weather and geographical disputes, causing the source to shrink, the price will rise, and the price of this product will also rise.

Second, the simplicity of the production process is related to the cost. If the method of making it requires exquisite equipment, expensive test drugs, and high energy consumption, the cost of this product will be high, and its price in the market will also be high.

Furthermore, the supply and demand of the market determine its price. If there are many seekers and there are few suppliers, the price will rise; if the supply exceeds the demand, the stock will be difficult to sell, and the price will tend to fall.

Also, the business plan is also the cause of the influence. Different businesses have different rules and sales strategies, and their pricing is also different.

Looking at past market conditions, the price of 5-amino-2-nitrotrifluorotoluene often fluctuates within a certain range. Either rise from time to time, or fall due to the market. To know the real-time price, it is advisable to consult the specialized business, the chemical industry, or visit the network of various industries to obtain the exact number.