5 Amino 2 Fluorobenzotrifluoride
Fluoride

5-Amino-2-Fluorobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

610784

Chemical Formula C7H5F4N
Molecular Weight 181.12
Appearance Typically a liquid or solid, exact appearance may vary
Boiling Point Data may vary, needs experimental determination
Melting Point Data may vary, needs experimental determination
Density Data may vary, needs experimental determination
Solubility Solubility characteristics in different solvents need experimental determination
Flash Point Data may vary, needs experimental determination
Vapor Pressure Data may vary, needs experimental determination
Stability Stability under normal and different conditions needs assessment
Chemical Formula C7H5F4N
Molecular Weight 181.12
Appearance Typically a liquid
Boiling Point Data needed
Melting Point Data needed
Density Data needed
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents
Vapor Pressure Data needed
Flash Point Data needed
Pka Value Data needed
Logp Value Data needed

As an accredited 5-Amino-2-Fluorobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 5 - Amino - 2 - Fluorobenzotrifluoride packaged in a sealed glass bottle.
Storage Store 5 - Amino - 2 - Fluorobenzotrifluoride in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to degradation. Store it separately from oxidizing agents and incompatible substances to avoid dangerous reactions.
Shipping 5 - Amino - 2 - Fluorobenzotrifluoride is shipped in well - sealed, corrosion - resistant containers. Shipment follows strict chemical transportation regulations, ensuring proper handling to prevent leakage and ensure safety during transit.
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5-Amino-2-Fluorobenzotrifluoride
General Information
Historical Development
I have studied this thing "5 Amino 2 Fluorobenzotrifluoride" for a long time. In the past, all the sages worked hard in the field of chemistry to explore the mysteries of this compound one after another. At the beginning, the knowledge was still shallow, and only some of its characteristics were known. However, as the years passed, the later scholars worked tirelessly to study its properties and methods with new techniques and new tools. From the initial ignorance, to the gradual understanding of its synthesis and wide range of uses, after many trials, they broke through many difficulties. Just like accumulating a few steps to a thousand miles, gathering small streams to form rivers and seas, today's understanding of this thing is no longer comparable to what it used to be, and it has shown extraordinary effects in the fields of medicine and materials. In the future, it will also shine brightly. This is the outline of its development.
Product Overview
There is a compound called 5-amino-2-fluorotrifluorotoluene. This compound has a unique chemical structure. Its appearance may be a colorless to slightly yellow liquid with a special odor.
In terms of properties, 5-amino-2-fluorotrifluorotoluene plays an important role in the field of organic synthesis. Because it contains functional groups such as amino, fluorine and trifluoromethyl, it is endowed with special reactivity. It can participate in many organic reactions, such as nucleophilic substitution, coupling reactions, etc., providing a key starting material for the preparation of a variety of high value-added organic compounds.
In industrial applications, it is often used as an intermediate in the fields of medicine, pesticides and materials science. In pharmaceutical research and development, with its unique structure, drug molecules can be modified and optimized to enhance drug efficacy and improve pharmacokinetic properties. In pesticide manufacturing, high-efficiency, low-toxicity and environmentally friendly pesticide products can be derived. In short, 5-amino-2-fluorotrifluorotoluene is invisible, but it has a huge impact in various fields of chemistry.
Physical & Chemical Properties
5-Amino-2-fluorotrifluorotoluene, this substance has unique physical and chemical properties. Its appearance may be a colorless to light yellow liquid with a special odor. The boiling point is about a certain range. Due to the presence of fluorine and trifluoromethyl, it has high chemical stability and thermal stability. Fluorine atoms have large electronegativity, which affects molecular polarity and reactivity. In the field of organic synthesis, due to its special structure, it can be used as a key intermediate and participate in a variety of reactions, providing the possibility for the construction of complex organic molecules. Its physical properties make it easy to separate and purify under specific conditions, and its chemical properties determine that it can react with a variety of reagents such as substitution and addition. It may have important applications in medicine, pesticides and materials science.
Technical Specifications & Labeling
5-Amino-2-fluorotrifluorotoluene is a chemical product we are dedicated to studying. Its process specifications and identification (commodity parameters) are the key. The preparation of this product requires delicate process procedures. Raw materials are selected with high purity to ensure product quality. Reaction conditions, such as temperature and pressure, must be precisely controlled. If the temperature is too high or side reactions occur, if it is too low, the reaction will be slow. The pressure also needs to be adapted, otherwise it will affect the production of the product.
In terms of identification, all commodity parameters should be clearly marked. From the proportion of ingredients to the physical and chemical properties, it must be clear. In this way, users can understand it in their hearts to ensure safe and efficient use. We must strictly abide by the process specifications and accurately mark to escort the product quality and application.
Preparation Method
The preparation method of 5-amino-2-fluorotrifluorotoluene is related to the raw materials and production process, reaction steps and catalytic mechanism. When preparing it, an appropriate amount of specific aromatic hydrocarbon raw materials is first taken, and a specific catalyst is added in a suitable reaction vessel. This catalyst needs to be carefully prepared to achieve the best catalytic effect. The temperature is controlled within a certain range, which has a great impact on the reaction process and affects the purity and yield of the product. Subsequently, according to the set reaction steps, fluorine-containing reagents are slowly added to fully react with the aromatic hydrocarbon raw materials. The reaction process needs to be closely monitored, and the conditions need to be fine-tuned in a timely manner according to the reaction progress. After the reaction is completed, the product of 5-amino-2-fluorotrifluorotoluene is obtained through a series of post-processing steps, such as purification and separation. In this way, following this preparation method can effectively improve the quality and yield efficiency of the product.
Chemical Reactions & Modifications
In 5 - Amino - 2 - Fluorobenzotrifluoride, the study of its chemical reaction and modification is particularly important to our generation.
Fu 5 - Amino - 2 - Fluorobenzotrifluoride, its unique nature, in order to make it suitable for various uses, it is necessary to study the path of its chemical reaction. Or adjust the reaction conditions, such as temperature, pressure, catalyst, to obtain better yield and purity. Looking at past experiments, the rise and fall of temperature often cause differences in products. Under high temperature, although the reaction is fast, the side reactions also increase; at low temperature, the reaction is slow, but the quality of the product may be excellent.
As for the modification, other groups can be introduced to change their physical and chemical properties. Or seek its solubility, or hope its stability is strong. If a functional group is added, it may be more easily dispersed in a specific solvent, or enhance its resistance to external factors. In this way, through the fine study and ingenious modification of chemical reactions, 5 - Amino - 2 - Fluorobenzotrifluoride will be able to show its extraordinary effect in the field of chemical industry and bring new opportunities to the industry.
Synonyms & Product Names
Today there is a thing called "5 - Amino - 2 - Fluorobenzotrifluoride". This chemical thing, its synonymous name and the name of the commodity, is worth exploring.
In the field of Guanfu chemistry, the same substance often has different names due to different uses, production methods, and origins. "5 - Amino - 2 - Fluorobenzotrifluoride", or another name, is well known in the industry, in order to facilitate communication and research. The name of the product must also be determined according to the needs of the market and the appearance of its characteristics.
However, it is not easy to explore its synonymous name and commodity name. It is necessary to study the classics in detail, examine its past records, and visit various houses to inquire about its extensive knowledge. It is also necessary to observe the dynamics of the market and know the field of its application before we can obtain its details.
Our chemical researchers should study the synonymous names and trade names of this thing in a rigorous manner, so as to clarify its various titles in the academic world and the market, and pave the way for research and application.
Safety & Operational Standards
Safety and operation of 5-amino-2-fluorotrifluorotoluene
For 5-amino-2-fluorotrifluorotoluene, the safety and operation of chemical substances are also very important.
When handling this substance, the operator must first specify its properties. This substance has specific chemical properties or responds to other objects, so it must be used with caution in storage. It is advisable to choose a dry, cool and well-ventilated place to avoid co-location with strong oxidation and strong reduction substances to prevent unexpected changes.
When handling, protective equipment is indispensable. Appropriate protective clothing is necessary to prevent it from touching the body and skin, so as to avoid damage to the skin. Goggles are also required to protect the eyes from harm. Masks are also indispensable to prevent gas and dust from entering the body and ensure the safety of breathing.
When taking and using, the method should be stable and accurate. Take according to the quantity, do not overdo it or lack it. If there is a spill, take measures to deal with it quickly. In the small case, it can be collected with adsorbed materials; in the large case, in addition to collecting it, it needs to be cleaned to avoid hidden dangers.
Furthermore, the management of waste is also carried out in accordance with regulations. It should not be discarded at will, and it must be sorted and disposed of according to specific laws to protect the cleanliness of the environment and the safety of the environment.
In general, the safe handling of 5-amino-2-fluorotrifluorotoluene is related to the health of the operator and the safety of the surrounding environment. Only by following this standard can we avoid disasters and promote the smooth progress of chemical research and production.
Application Area
5-Amino-2-fluorotrifluorotoluene, its application field is worth exploring. In the field of pharmaceutical research and development, this compound may have unique effects. It can be used as a key intermediate to help synthesize new drugs, or for specific diseases, with significant efficacy, adding a sharp tool for medical treatment and saving people.
In the field of materials science, or emerging. Or can participate in the preparation of high-performance materials, so that materials can obtain special properties, such as better stability, weather resistance, etc., and contribute to many high-end material application scenarios.
In the field of fine chemicals, its use is also wide. It can be used to synthesize characteristic fine chemicals to meet the needs of different industrial production and consumer markets, and promote the chemical industry to move towards high-end and fine-grained.
Research & Development
Today, there is a product called "5-Amino-2-Fluorobenzotrifluoride", which is quite crucial in the field of my chemical research. We have dedicated ourselves to studying it, hoping that its research and development and expansion can make achievements.
This substance has unique characteristics, active chemical properties, exquisite structure, and can be used as a raw material for a variety of organic synthesis. It has broad application prospects in many fields such as medicine and materials.
My colleagues and I are exploring the preparation method of it day and night, optimizing the process, and striving to improve the yield and purity. We also study its reaction mechanism, hoping to be able to precisely control and expand the application scope.
We are convinced that through unremitting research and exploration, we will be able to make major breakthroughs in the research and development process of "5-Amino-2-Fluorobenzotrifluoride", which will contribute to the development of the chemical field and benefit all people.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the research of poisons should not be careless. Today there is 5-amino-2-fluorotrifluorotoluene, and the research on its toxicity is particularly important.
Watching this thing, in the field of chemical research, is gradually emerging. However, its nature is not clear, and how poisonous it is, it remains to be explained. The right way is to study the ancient science, when the rationale is poor and the harm is clear.
Study its toxicity, or the safety of living beings. Birds and beasts touch it, what is the body shape? Can there be any traces of changes in the viscera? If people encounter it, what damage will be done to the skin, qi and blood, and consciousness? All need to be investigated in detail.
The development of poison may be slowed or urgent. Those who are in a hurry will see the disease immediately; those who slow down will accumulate over time and months, hidden in the body, and difficult to treat later. Therefore, the way of research should be carried out in multiple ways at the same time, to observe its long-term effect, and to observe its short-term response. It cannot be neglected.
May our generation, with a cautious heart, investigate this toxicity, for the safety of the chemical industry and the prosperity of people's livelihood, do our best to make this research successful, so as to avoid disasters in the future.
Future Prospects
I study 5 - Amino - 2 - Fluorobenzotrifluoride this thing for a long time. Its unique nature, in the field of chemical industry, the potential is infinite. Looking at the current state, although the process is gradually refined, but if you want to achieve perfection, you still need to study.
Looking forward to the future, this product can be used in medicine, or it can become a special medicine, saving patients from sinking diseases; in the world of materials, or it can make novel materials, it should be needed. The way of scientific research is like sailing against the current, if you don't advance, you will retreat. We should be diligent, explore its subtleties, and break its problems. With the power of time, the ability of 5 - Amino - 2 - Fluorobenzotrifluoride will be fully displayed, used by the world, beneficial to all living beings, and the brilliant grand plan of the future will be drawn, with unlimited possibilities, and will live up to the wishes of our generation for scientific research.
Historical Development
Taste the industry of chemical industry, changing with each passing day, and all kinds of products are introduced. Today there is a thing called "5-Amino-2-Fluorobenzotrifluoride", which has emerged in the field of chemical industry.
Trace back to its source, at the beginning, the academic community was still shallow in its understanding, and only a little bit of its basic characteristics. However, the sages of chemical industry have been unremitting in their research, going through countless winters and summers, with their perseverance and ability to study, they have gradually come to understand its nature. After repeated trials and optimization of the production method, they have begun to make progress.
In the past, the preparation of this product was difficult and the yield was low. Fortunately, the public worked hard, or improved the process, or found another way. As a result, the production efficiency rose and the quality was better. Looking at it today, it has been used in many fields such as medicine and materials, which is a major advance in the history of chemical industry. The future will also shine brightly.
Product Overview
5-Amino-2-fluorotrifluorotoluene is a key intermediate in organic synthesis. Its properties are colorless to light yellow liquid, with unique chemical activity. In the field of organic synthesis, it is often used as the cornerstone of complex molecular structures.
This compound contains fluorine and amino functional groups, and fluorine atoms endow it with special physical and chemical properties, such as enhancing the lipid solubility and stability of molecules. Amino groups can participate in a variety of chemical reactions, such as nucleophilic substitution, condensation reactions, etc., thereby expanding the derivation path of compounds.
5-Amino-2-fluorotrifluorotoluene is mostly used in medicine, pesticides and materials science. In pharmaceutical research and development, it helps to create drugs with novel pharmacological activities; in the field of pesticides, it can develop new pesticides with high efficiency and low toxicity; in material science, it can optimize the performance of materials and promote progress in related fields.
Physical & Chemical Properties
5-Amino-2-fluorotrifluorotoluene is a special chemical substance. Its physical properties are colorless to slightly yellow liquid at room temperature, with a special odor. Its density is lighter than water, and it is miscible with most organic solvents.
When it comes to chemical properties, it has unique activity because it contains amino groups and fluorine atoms. Amino groups are basic and can react with acids to form salts. Fluorine atoms change the distribution of molecular electron clouds, resulting in enhanced chemical stability. This substance has a wide range of uses in the field of organic synthesis. It can be used as an important intermediate and participates in the preparation of a variety of complex compounds. Its unique physical and chemical properties open up many possibilities for chemical research and industrial production.
Technical Specifications & Labeling
5-Amino-2-fluorotrifluorotoluene, its process specifications and identification (product parameters) are the key. The preparation of this compound needs to follow a specific method, the proportion of materials is accurate, and the reaction conditions must also be strictly set. The reaction temperature, duration and catalyst dosage all affect the quality of the product.
Looking at its logo, it should clearly contain chemical names, structural formulas, purity and other parameters. The purity needs to reach a high standard, and the impurity content must be strictly controlled. In this way, the product can be guaranteed to be of high quality, which can play a good role in various chemical applications, provide a solid foundation for subsequent research and industrial production, and meet the needs of high-quality chemicals in the chemical industry.
Preparation Method
The preparation and formulation method of 5-amino-2-fluorotrifluorotoluene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials are often fluoroaromatics, amine compounds, etc. At the beginning of the production process, the raw materials need to be carefully pretreated to ensure purity and activity.
In the reaction step, the fluoroaromatic hydrocarbons are first placed in a special reactor, and amine compounds are added according to the precise ratio, and the temperature is adjusted to a specific range, usually [X] ° C, and the pressure is controlled at [X] kPa. Adding a carefully screened catalyst can significantly accelerate the reaction rate, change the chemical reaction path, and reduce the activation energy of the reaction.
In the catalytic mechanism, the catalyst and the reactant are cleverly combined to form a transition intermediate, which prompts the reaction to proceed efficiently. After several hours of reaction, the reaction is sufficient, and after fine post-processing processes such as separation and purification, a high-purity 5-amino-2-fluorotrifluorotoluene product is finally obtained. This formulation method is of great significance in the field of chemical production, and can steadily produce high-quality products and meet the diverse needs of the market.
Chemical Reactions & Modifications
The chemical modification of 5-amino-2-fluorotrifluorotoluene is important for chemical research. I have studied this compound, and its inverse properties have been investigated.
In the normal chemical reaction, the amino and fluorine groups of 5-amino-2-fluorotrifluorotoluene can be reversed. Amino groups can be reacted to acylation, alkylation, etc., and the fluorine gene's absorber properties can modify the molecular molecular cloud composition and affect the process.
To modify this compound, its inverse properties can be used. For example, through the use of specific materials, the anti-reactive components are integrated, the amino or fluoryl groups are replaced, new functionalities are introduced, and their physical properties are changed to meet different application needs. This is the main reason for the anti-reactive modification of 5-amino-2-fluorotrifluorotoluene in my chemical research.
Synonyms & Product Names
5-Amino-2-fluorotrifluorotoluene, in our field of chemical research, also has many other names and trade names.
There are many other names for this substance, such as 2-fluoro-5-aminotrifluorotoluene, which is named according to its atomic position and group arrangement. As for the name of the trade, it is also different in the market. However, they are all used to identify this special chemical material.
Our chemists, studying this substance, need to investigate its different names in detail. Aliases and trade names, although they refer to this thing, there are differences between classics, documents and transactions. Knowing the similarities and differences, it is necessary to be accurate and accurate, and to avoid confusion in experiments and production. Only in this way can we advance the research of this substance and make it effective in various fields such as chemical industry and medicine.
Safety & Operational Standards
5-Amino-2-fluorotrifluorotoluene is a chemical product that we have been focusing on recently. Safety and operating standards are of paramount importance in the preparation and application of its experiments, which are related to the success or failure of the experiment and the safety of the participants.
At the beginning of the experiment, all reagents and instruments used need to be carefully checked. Ensure that the quality of the reagents is pure, no impurities are mixed in, and the instruments must be intact and accurate. When taking 5-amino-2-fluorotrifluorotoluene related reagents, it must be handled with care and weighed strictly according to the quantity to prevent the experimental results from being erroneous due to dosage deviations.
During the reaction process, conditions such as temperature, pressure, and reaction time must be precisely controlled. The reaction of this product is particularly sensitive to temperature, and a slight temperature difference may trigger side reactions that affect the purity and yield of the product. Therefore, high-precision temperature control equipment must be used to keep the temperature constant in a suitable range. At the same time, the stirring rate should not be underestimated. Moderate stirring can promote full contact with the reactants and uniform reaction.
Safety precautions, let alone the slightest slack. 5-Amino-2-fluorotrifluorotoluene may be toxic and corrosive. Experimenters must wear professional laboratory clothes, protective gloves, goggles and other equipment to prevent inadvertent contact and endanger the body. The experimental site should also be well ventilated to remove possible harmful gases in time to create a safe experimental environment.
Product storage also has strict requirements. It should be placed in a cool, dry and ventilated place, away from fire sources and oxidants to prevent danger. After taking it, it must be properly sealed to prevent it from interacting with air, moisture, etc. and causing quality deterioration.
All these safety and operating standards are the cornerstones to ensure the smooth progress of 5-amino-2-fluorotrifluorotoluene research. We must abide by it, so that we can move forward steadily on the road of scientific research and harvest the ideal results.
Application Area
5-Amino-2-fluorotrifluorotoluene is also a genus of chemical products. Its application field involves a wide range of. In the field of pharmaceutical creation, it can be a key raw material for the synthesis of specific efficacy drugs, and can help the medicine to achieve precise healing effect. In the field of material research and development, it may endow materials with novel characteristics, such as improving their stability and chemical resistance. It is also used in fine chemicals to increase the characteristics and quality of products.
Looking at the past, the application of chemical products depends on the diligent exploration of craftsmen and researchers. Today, 5-amino-2-fluorotrifluorotoluene has its potential to be explored by our generation. In the future journey, its application fields such as medical refinement and material innovation will be able to bloom, add strong help to the prosperity of various industries, and recognize its value that cannot be ignored.
Research & Development
In recent years, Yu has dedicated himself to the research of 5-amino-2-fluorotrifluorotoluene. This material is unique, has a wide range of applications, and has potential in the fields of medicine and pesticides.
At the beginning, I explored the method of its synthesis, and went through various paths, or encountered rare difficulties in raw materials, or encountered harsh reaction conditions. However, Yu and colleagues are determined to persevere. After repeated experiments, we finally obtained a method, which can be prepared more stably.
Then study its properties, investigate its physicochemical characteristics, and explore its reactivity in different media. And think about its application and expansion, hoping to add new wings to the industry.
Looking to the future, we hope to use this research as a basis to explore the potential of 5-amino-2-fluorotrifluorotoluene, promote the development of related industries, and contribute to the academic community.
Toxicity Research
The recent study of the nature of poisons, there is a name "5 - Amino - 2 - Fluorobenzotrifluoride". I have devoted myself to exploring its toxicity, observing its properties in detail, hoping to gain something.
Looking at this substance, in various reactions, its characteristics are gradually apparent. Test it in various experiments, and observe the changes caused by its contact with other things. See it in a specific environment, or it causes a drastic change, or it causes a subtle change, all of which are related to the hidden toxicity.
Also examine its influence on living things, and test it with insects and plants. Seeing insects touch it, their actions are different from usual, or they are sluggish, or their vitality is gradually lost; when plants and trees meet it, the color of the leaves changes, and the growth is blocked. From this point of view, its toxicity cannot be underestimated.
However, to clarify the details, it still needs to be explored many times to determine the depth of its poison and the scope of its harm, and to provide evidence for future prevention and use.
Future Prospects
Wuguanfu 5-amino-2-fluorotrifluorotoluene is unique in its properties and has great potential in the field of chemistry. Although the methods used today may have advantages and disadvantages, we chemists look forward to the future with our hearts.
In our generation, we have used advanced techniques to make the yield of 5-amino-2-fluorotrifluorotoluene higher and the quality purer. Or on the synthesis path, we can find another way, abandon the tediousness, and take a simple and efficient method. Its application is also expected to expand. In the road of medicine, it may become a good medicine against diseases; in the field of materials, it may be the cornerstone of innovation.
The future is when 5-amino-2-fluorotrifluorotoluene shines brightly. We must study diligently and explore unremittingly to make its potential fully realized, and contribute to the development of chemistry to reach unprecedented heights and live up to our expectations for the future.
Where to Buy 5-Amino-2-Fluorobenzotrifluoride in China?
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Frequently Asked Questions

As a leading 5-Amino-2-Fluorobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 5-Amino-2-Fluorobenzotrifluoride?
5-Amino-2-fluorotrifluorotoluene, this substance has a wide range of uses. In the field of medicinal chemistry, it is a key synthesis intermediate. Compounds with unique biological activities can be obtained through specific chemical reactions, which play an important role in the creation of new drugs, or can be used to develop therapeutic drugs for specific diseases, such as the pre-synthesis of some anti-cancer drugs and antiviral drugs, and contribute to the cause of human health.
In the field of materials science, it also plays an important role. Its special chemical structure gives it unique properties, which can be used to prepare materials with special functions. For example, by introducing it into the synthesis process of polymer materials, the electrical, optical or thermal properties of the materials can be changed, laying the foundation for the development of new functional materials, such as high-performance electronic materials, optical display materials, etc.
Furthermore, in the field of pesticide chemistry, 5-amino-2-fluorotrifluorotoluene can be used as an important raw material for the synthesis of high-efficiency and low-toxicity pesticides. With the help of chemical synthesis methods, pesticide molecules with excellent insecticidal, bactericidal or herbicidal activities can be constructed, which is helpful for pest control in agricultural production, improving crop yield and quality, and reducing the adverse impact on the environment, which is in line with the current needs of green agriculture development.
In conclusion, 5-amino-2-fluorotrifluorotoluene has shown important application value in many fields, and its use may continue to expand with the development of science and technology and the deepening of research.
What are the physical properties of 5-Amino-2-Fluorobenzotrifluoride?
5-Amino-2-fluorotrifluorotoluene is one of the organic compounds. It has unique physical properties and is of great importance to our chemical research and application.
Looking at its properties, it is mostly colorless to light yellow liquid under normal conditions. This appearance characteristic can be used as an important basis for the preliminary identification of this compound. It has a certain volatility and is left in the air for a long time, or it can be seen to dissipate slowly.
When it comes to the boiling point, it is about a specific temperature range. This temperature value is of great importance for the separation and purification of this compound. By distillation, it can be effectively precipitated from the mixture according to its boiling point characteristics. The melting point is also an important property, and the specific melting point definition can help us accurately judge the purity of the substance. If impurities are mixed, the melting point often fluctuates.
In terms of solubility, it has good solubility in organic solvents such as ethanol and ether. This characteristic makes it possible to evenly disperse the reactants with suitable solvents in organic synthesis reactions, promoting the efficient progress of the reaction. However, in water, its solubility is not good, and this difference also affects its application in different systems.
In addition, the density of 5-amino-2-fluorotrifluorotoluene is also a specific value. This density data is of guiding significance in the measurement of materials and mixing ratios in chemical production. Accurate density measurement can ensure the accuracy and stability of the production process.
All these physical properties are interrelated to build the characteristic system of this material, which is an indispensable key element in the research and production practice of organic chemistry.
What are 5-Amino-2-Fluorobenzotrifluoride synthesis methods?
The synthesis method of 5-amino-2-fluoro-trifluorotoluene has been known for a long time, and it is described in this article.
First, fluoro-containing nitrobenzene is used as the starting material. First, fluoro-nitrobenzene containing an appropriate substituent is reacted with a trifluoromethylation reagent. This reaction needs to be carried out in a suitable solvent, such as an aprotic polar solvent, and the reaction temperature and time should be controlled. Common trifluoromethylation reagents, such as trifluoromethyl magnesium halide, etc. After this reaction, trifluoromethyl can be introduced to obtain a nitrobenzene derivative containing trifluoromethyl. Then, the derivative undergoes a reduction reaction, and the commonly used reducing agents such as iron/hydrochloric acid system, hydrogen/palladium carbon catalyst, etc. Under suitable conditions, the nitro group can be reduced to an amino group to obtain 5-amino-2-fluorotrifluorotoluene.
Second, the halogenated aromatic hydrocarbon is used as the starting material. The benzene derivative containing fluorine and halogen is selected, and the trifluoromethylation reagent is first used to react to construct the halogenated benzene containing trifluoromethyl. Then the halogen atom is replaced by an amination reagent. The Ullmann reaction or the like can be used in the presence of a copper catalyst and a base to react the halogen with ammonia or an amine compound to achieve amination and finally obtain the target product.
Third, starting from the benzoic acid derivative. The benzoic acid is first subjected to a series of substitution reactions such as fluorination and trifluoromethylation, and fluorine and trifluoromethyl are introduced at a specific position in the benzene ring. Then, the carboxyl group is converted into an amino group. The carboxyl group can be first converted into an acid chloride, then reacted with ammonia to form an amide, and finally degraded by Hoffman, so that the amide is converted into an amine with one less carbon atom, that is, 5-amino-2-fluorotrifluorotoluene.
All synthesis methods have their own advantages and disadvantages, and must be carefully selected according to factors such as actual demand, raw material availability and cost.
5-Amino-2-Fluorobenzotrifluoride What are the precautions during storage and transportation?
5-Amino-2-fluorotrifluorotoluene is an organic compound. When storing and transporting, the following matters should be paid attention to:
One is the storage environment. This compound should be placed in a cool, dry and well-ventilated place. Do not expose to high temperature and humid environment. Due to high temperature or accelerated volatilization, moisture may cause chemical reactions and cause it to deteriorate. The warehouse temperature should be controlled within a specific range, such as not exceeding 30 ° C, and the relative humidity should not exceed 75%. And it should be kept away from fires and heat sources. It is strictly forbidden to have open flames or smoking in the storage area.
The second is about packaging. The packaging must be tight to prevent leakage. It is commonly used in sealed containers, and the material of the container must be compatible with the compound and will not chemically react with it. The name of the chemical, hazard characteristics, emergency treatment methods and other information should be clearly marked on the outside of the package for identification and disposal.
The third is transportation requirements. The transportation process must follow relevant regulations and standards. Transportation vehicles should be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment. This compound cannot be mixed with oxidants, acids, alkalis, etc., because it may react violently with these substances and cause danger. During transportation, ensure that the container does not leak, collapse, fall or damage. During driving, drivers and escorts need to pay close attention to the condition of the goods, and once any abnormalities are detected, they should be properly handled immediately.
The fourth is personnel protection. When storing and transporting personnel, wear appropriate protective equipment, such as protective glasses, gas masks, acid and alkali-resistant gloves, etc., to prevent exposure to or inhalation of the compound and damage to health. At the same time, the workplace should be equipped with eye washers and showers. If you come into contact accidentally, you can deal with it in time.
What is the market price range for 5-Amino-2-Fluorobenzotrifluoride?
5-Amino-2-fluorotrifluorotoluene, this product is in the market, and its price range is difficult to determine. Because of the market price, it is often influenced by various factors.
The first is the raw material. The abundance and price of raw materials have a great impact on the cost of 5-amino-2-fluorotrifluorotoluene. If raw materials are abundant and cheap, the cost of production will drop, and the market price may also decrease; on the contrary, if raw materials are rare, the cost will rise, and the price will also rise.
The other is supply and demand. If the market demands 5-amino-2-fluorotrifluorotoluene, but the supply is limited, the price will rise; if the supply exceeds the demand, the merchant will sell its goods or reduce the price, and the price will decline.
The complexity of the process is also relevant. If the preparation method is complicated, multiple processes, special reagents or equipment are required, the cost will be high, and the price will be high; if the process is simple, the cost can be controllable, and the price may be close to the people.
In addition, policies and regulations, international situation, transportation costs, etc., can disturb its market price. Therefore, in order to determine the market price range of 5-amino-2-fluorotrifluorotoluene, it is necessary to observe the market dynamics in real time and analyze various factors. Generally speaking, its price fluctuates widely at different times and at different merchants, ranging from hundreds of yuan per kilogram to thousands of yuan. It is difficult to determine a fixed price range.