What is the main application field of 4-Cyano-2-fluorobenzotrifluoride~ alpha, alpha, alpha, 3-Tetrafluoro-p-tolunitrile

4-Cyano-2-fluorotrifluorotoluene (4-Cyano-2-fluorobenzotrifluoride), also known as α, α, α, 3-tetrafluoro-p-toluonitrile （α,α,α, 3-Tetrafluoro-p-tolunitrile), is widely used and has important applications in many fields.

It plays an important role in the field of pharmaceutical synthesis. Fluorinated organic compounds can significantly affect the physiological activity, metabolic stability and fat solubility of drugs in drug molecules. The special structure of 4-cyano-2-fluorotrifluorotoluene makes it a key intermediate for the synthesis of a variety of new drugs. For example, it can be used to develop innovative drugs for specific disease targets. With its unique chemical structure, it can enhance the affinity and selectivity of drugs and targets, thereby enhancing the efficacy and opening up new paths for pharmaceutical research and development.

In the field of materials science, it also has extraordinary functions. With the advancement of science and technology, the demand for high-performance materials is increasing day by day. 4-cyano-2-fluorotrifluorotoluene can be used as a raw material to participate in the synthesis of special polymer materials, such as fluoropolymers with excellent chemical resistance and high temperature resistance. Such polymers are indispensable in high-end fields such as aerospace, electronics and appliances. They can be used in the manufacture of aero-engine components, protective coatings for electronic circuit boards, etc., which greatly improves the performance and service life of materials.

In addition, it also plays an important role in the field of pesticide chemistry. Fluorinated pesticides are known for their high efficiency, low toxicity and environmental friendliness. 4-Cyano-2-fluorotrifluorotoluene can be used as a key starting material for the synthesis of new fluorinated pesticides. After chemical modification and reaction, specific pesticides against different crop diseases and pests can be prepared, which helps to improve crop yield and quality while reducing adverse effects on the environment.

Overall, 4-cyano-2-fluorotrifluorotoluene has shown great application potential in many key fields such as medicine, materials science, and pesticide chemistry, promoting the sustainable development and innovation of related industries.

What are the physical properties of 4-Cyano-2-fluorobenzotrifluoride~ alpha, alpha, alpha, 3-Tetrafluoro-p-tolunitrile

4-Cyano-2-fluorotrifluorotoluene (4-Cyano-2-fluorobenzotrifluoride), also known as α, α, α, 3-tetrafluoro-p-toluonitrile （α,α,α, 3-Tetrafluoro-p-tolunitrile), this is an organic compound, which is very important in the field of chemical synthesis. Its physical properties are as follows:
1. ** Appearance properties **: Usually colorless to light yellow liquid, pure substance under specific conditions or colorless and transparent, under normal ambient light and visual conditions, clearly recognizable. This appearance feature provides an intuitive basis for identifying its state during chemical production, storage and use.
2. ** Melting boiling point **: Melting point is about - 20 ° C, boiling point is 158 - 160 ° C. Melting point indicates that the substance will change from liquid to solid in a low temperature environment, and the boiling point is displayed at a specific pressure, and it will vaporize when heated to the corresponding temperature. These data are crucial for processing at different temperatures. Operations such as distillation and separation require precise control of temperature according to the melting boiling point.
3. ** Density **: about 1.41 g/cm ³, which is denser than water, meaning that it will sink to the bottom when mixed with water. In processes involving the coexistence of this substance with water or other liquids of different densities, density information is of great significance for separation operations.
4. ** Solubility **: Insoluble in water, but soluble in common organic solvents, such as ether, acetone, chloroform, etc. This solubility characteristic determines its solvent selection range in organic synthesis reactions, contributing to the smooth progress of the reaction, as well as the separation and purification of the product.
5. ** Vapor pressure **: The vapor pressure is lower at room temperature, indicating that its volatility is relatively weak. This property affects the degree of volatilization loss during storage and use, as well as the potential impact on the air quality of the working environment. Lower vapor pressure means that under conventional storage and operating conditions, the amount of volatilization into the air is relatively small, which reduces the risk of harm to the environment and the health of operators to a certain extent.

What is the chemical synthesis method of 4-Cyano-2-fluorobenzotrifluoride~ alpha, alpha, alpha, 3-Tetrafluoro-p-tolunitrile

4-Cyano-2-fluorotrifluorotoluene (4-Cyano-2-fluorobenzotrifluoride), also known as α, α, α, 3-tetrafluoro-p-toluonitrile （α,α,α, 3-Tetrafluoro-p-tolunitrile), is chemically synthesized as follows:

The starting material can be selected from suitable fluoroaromatic hydrocarbons, such as p-fluorotoluene derivatives. First, the starting material is cyanylated. This reaction requires the selection of suitable cyanide reagents under specific reaction conditions, such as potassium cyanide (KCN) or sodium cyanide (NaCN), but due to the strong toxicity of these two, the actual operation needs to be cautious. In a suitable solvent, such as dimethyl sulfoxide (DMSO) or N, N-dimethylformamide (DMF), and a catalyst, such as a phase transfer catalyst, is added to promote the smooth progress of the cyanide substitution reaction.

Next, the trifluoromethylation step is carried out. Nucleophilic trifluoromethylation reagents can be used, such as sodium trifluoromethylsulfonate (CF 🥰 SO 🥰 Na), etc. Under the action of bases, such as potassium carbonate (K 🥰 CO 🥰) or potassium tert-butyl alcohol (t-BuOK), trifluoromethyl negative ions can be formed and react with the substrate to introduce trifluoromethyl into the appropriate position.

For the introduction of fluorine atoms, if the number of fluorine atoms in the starting material is insufficient, nucleophilic fluorination reagents, such as potassium fluoride (KF), can be used to introduce fluorine atoms into the molecular structure through nucleophilic substitution in the presence of phase transfer catalysts such as crown ethers. This process requires controlling the reaction temperature, time, and proportion of reactants to ensure that fluorine atoms are accurately replaced to the desired position.

During the entire synthesis process, it is necessary to strictly control the reaction conditions of each step, including temperature, pressure, reaction time, amount of reactants and catalysts, etc. At the same time, each step of the reaction product should be carefully separated and purified. Common methods include distillation, column chromatography, etc., to ensure the purity and yield of the final product, so as to successfully synthesize 4-cyano-2-fluorotrifluorotoluene.

What is the price range of 4-Cyano-2-fluorobenzotrifluoride~ alpha, alpha, alpha, 3-Tetrafluoro-p-tolunitrile in the market?

4-Cyano-2-fluorotrifluorotoluene (4-Cyano-2-fluorobenzotrifluoride), also known as α, α, α, 3-tetrafluoro-p-toluonitrile （α,α,α, 3-Tetrafluoro-p-tolunitrile), is a key intermediate in the field of organic synthesis, and has applications in medicine, pesticides, and materials science.

It is not easy to know the exact market price range. Because the market price is often influenced by many factors, such as raw material costs, ease of production process, market supply and demand, preparation scale, and regional differences in sales.

At one end of the cost of raw materials, if the supply of starting materials required to synthesize this compound is scarce or the price fluctuates violently, the price of the finished product will also fluctuate. If the production process is complicated and the equipment and technical requirements are strict, the production cost will rise, which will affect the selling price.

In terms of market supply and demand, if there is a surge in demand for it in fields such as pharmaceutical research and development, and the production supply is difficult to match for a while, the price may rise; on the contrary, if the market demand is weak and the supply is excessive, the price may fall.

Preparation scale also has an impact. In large-scale production, due to the scale effect, the unit cost may be reduced and the price may be more affordable; small-scale preparation is more expensive and the selling price will be higher.

As for the sales area, the price will vary depending on the level of economic development and logistics costs in different regions.

Therefore, it is difficult to determine the price range without carefully examining the specific market situation, manufacturers and transaction details. For details, you can consult chemical product suppliers, browse professional chemical product trading platforms, or consult industry veterans to obtain more accurate price information.

What are the manufacturers of 4-Cyano-2-fluorobenzotrifluoride~ alpha, alpha, alpha, 3-Tetrafluoro-p-tolunitrile?

4-Cyano-2-fluorotrifluorotoluene (4-Cyano-2-fluorobenzotrifluoride), also known as α, α, α, 3-tetrafluoro-p-toluenitrile （α,α,α, 3-Tetrafluoro-p-tolunitrile), the manufacturer of this product, there are many of the following.

In the chemical industry, some well-known large factories, such as [specific large factories 1], their exquisite technology, profound technology, in the preparation of fluorinated compounds is quite accomplished. The factory has advanced equipment and mature processes, precise control of the production of such fine chemicals, high product quality, and a good reputation in the industry.

Another [specific large factory 2] is also involved in the production of this compound. The factory focuses on R & D and innovation, continuously optimizes the production process, and strives to produce high-quality products in an efficient and environmentally friendly way. With its strict requirements for quality, the 4-cyano-2-fluorotrifluorotoluene produced also has a place in the market.

In addition to large factories, some small enterprises specializing in fine chemicals, such as [Specific Small Factory 1], although the scale is relatively small, they focus on the production of fine chemicals in specific fields. The production of 4-cyano-2-fluorotrifluorotoluene also has a unique process, and the products are highly targeted to meet the needs of specific customers.

Furthermore, [Specific Small Factory 2] and other enterprises, with flexible business strategies and keen insight into the market, can also adjust product specifications in the production of 4-cyano-2-fluorotrifluorotoluene in a timely manner to meet the needs of the changing market.

In summary, the manufacturers of 4-cyano-2-fluorotrifluorotoluene, with their own sizes and characteristics, jointly promote the supply and development of this product in the chemical market.