4 Chloro 3 Fluorobenzotrifluoride
Fluoride

4-Chloro-3-Fluorobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

905613

Chemical Formula C7H3ClF4
Molar Mass 196.547 g/mol
Appearance Colorless liquid
Boiling Point 145 - 147 °C
Density 1.388 g/mL at 25 °C
Vapor Pressure Data varies with temperature
Flash Point 41.1 °C
Solubility Insoluble in water, soluble in organic solvents
Odor Typical aromatic - halogenated odor
Chemical Formula C7H3ClF4
Molecular Weight 196.545
Appearance Colorless to light yellow liquid
Boiling Point 144 - 146 °C
Density 1.408 g/mL at 25 °C
Solubility Insoluble in water, soluble in organic solvents
Flash Point 37 °C
Refractive Index 1.4185 (20 °C)

As an accredited 4-Chloro-3-Fluorobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500 - gram bottle packaging for 4 - Chloro - 3 - Fluorobenzotrifluoride chemical.
Storage 4 - Chloro - 3 - Fluorobenzotrifluoride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials. Avoid storing near incompatible substances to prevent chemical reactions. Regularly check for leaks or container integrity.
Shipping 4 - Chloro - 3 - Fluorobenzotrifluoride is shipped in accordance with strict chemical regulations. It's typically in sealed, corrosion - resistant containers, transported by specialized carriers ensuring proper handling to prevent spills and maintain safety.
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4-Chloro-3-Fluorobenzotrifluoride
General Information
Historical Development
4-Chloro-3-fluoro-trifluorotoluene is also a chemical substance. Its initial discovery originated from the research and exploration of various scholars in chemistry. In the past, scholars gradually discovered the characteristics of this compound in the laboratory with precision and diligence.
At first, only its basic properties were known, and after years of research, its reaction mechanism and synthesis path were refined. Early synthesis methods were complex and inefficient, but scholars tried new methods unremitting. In recent years, the synthesis technology has become more mature, and the yield has also increased significantly. From ignorance to skillful control, the development process of this compound has been like a long river, witnessing the continuous progress of the chemical field, from shallow to deep, introducing new ideas, and expanding a wide range of fields for subsequent applications.
Product Overview
4-Chloro-3-fluorotrifluorotoluene is also an organic compound. It is a colorless to light yellow liquid with a special odor. This substance has a wide range of uses in the chemical industry and is often a key raw material for the synthesis of many fine chemicals.
Its chemical properties are active, and it can participate in a variety of chemical reactions due to the presence of halogen atoms such as chlorine and fluorine. In organic synthesis, complex organic molecular structures can be constructed through reactions such as substitution and addition.
The preparation method often takes specific aromatic compounds as the starting materials and is formed through a series of steps such as halogenation and fluorination. The reaction process requires precise control of conditions, such as temperature, pressure, catalyst, etc., to ensure product purity and yield.
In industrial production and laboratory research, it is necessary to pay attention to its safety. Due to its certain toxicity and corrosiveness, strict safety procedures must be followed during operation, and protective measures must be taken to prevent harm to the human body and the environment.
Physical & Chemical Properties
4-Chloro-3-fluorotrifluorotoluene is an organic compound. Its properties are at the end of physics and chemistry.
On its physics, it is at room temperature, or a colorless liquid with a special odor. Its boiling point and melting point are all characteristics. The number of boiling points is about [X] ° C, and the melting point is about [X] ° C, which is related to the change of its phase state. The density is also fixed, about [X] g/cm ³, which is related to the mixing of it with other substances.
As for the chemical properties, it contains chlorine, fluorine and other atoms, and the chemical activity is obvious in it. Under suitable conditions, it can react with bases, and chlorine atoms are easily replaced by hydroxyl groups to form corresponding alcohols. It can also meet with nucleophiles, and fluorine atoms may participate in them, causing structural changes. And because it contains trifluoromethyl, it has certain stability, but it may also react before strong oxidation agents. This is a brief description of the physical and chemical properties of 4-chloro-3-fluorotrifluorotoluene.
Technical Specifications & Labeling
4-Chloro-3-fluorotrifluorotoluene is also an important product in the chemical industry. Its technical regulations and labels (commodity parameters) are related to the quality and cannot be ignored.
Those who have technical regulations, the method of preparation is also. If you want to get pure products, you need to follow delicate recipes. Its reaction device must be clean and suitable; the matching of materials should be good at weighing. The control of temperature and humidity is also the key. If it exceeds the degree, the quality may change.
Those who are marked are clear about its nature. Looking at its color, it should be clear and transparent; smelling its gas, it should have a specific taste. Measuring its degree, specific gravity, and number of melting boils are all accurate. The content of impurities must be very small, just in line with the regulations of high-quality products.
Those who make this product strictly abide by the technical regulations and specify the logo in detail, so that they can produce good products to meet the needs of various industries and develop their functions in the field of chemical industry, benefiting the country and the people.
Preparation Method
The raw materials and production process, reaction steps and catalytic mechanism of 4-chloro-3-fluorotrifluorotoluene are the key.
The raw materials should be carefully selected to adapt to the formation of this compound. The production process needs to be carefully planned, and each step is related to the purity and yield of the product. The reaction steps should be advanced in an orderly manner, or through substitution and addition reactions, and the reaction conditions such as temperature, pressure, and catalyst dosage should be strictly controlled.
As for the catalytic mechanism, it is necessary to find a suitable catalyst to promote the efficient progress of the reaction. Or choose a metal catalyst to reduce the activation energy of the reaction and accelerate the reaction rate by means of its activity check point. During the reaction process, careful monitoring and timely adjustment are made to make the reaction smooth and achieve the best production effect, so as to produce 4-chloro-3-fluorotrifluorotoluene of good quality.
Chemical Reactions & Modifications
The chemical changes and performance improvement of Fu 4-chloro-3-fluoro-trifluorotoluene are of great concern to our chemical researchers. Its chemical reaction depends on many factors, such as temperature, solvent properties, catalyst effects, etc. When adjusting the appropriate temperature, the reaction speed can be accurate, or the yield can be improved. And different solvents can also make the reaction pathways different. There are those that promote the reaction, and those that are slow.
As for the change of properties, it can be caused by modifying the structure of its molecules. Or add groups, or change bonds to increase its stability, or change its solubility, or adjust its chemistry. All of this depends on fine calculations and clever thinking. After many tests, good results have been obtained, making 4-chloro-3-fluorotrifluorotoluene more widely used and more effective in various fields, so as to meet the needs of the world and promote the progress of chemistry.
Synonyms & Product Names
4-Chloro-3-fluorotrifluorotoluene is also a chemical substance. Its synonyms are quite important to scholars. This thing is in the industry, or has another name, in order to meet the practical convenience.
In the ancient books, looking for its synonyms, it can be seen that its names are applied in different situations. The names are different but the same, but due to industry traditions and regional differences, the names have also changed.
Test 4-chloro-3-fluorotrifluorotoluene, or there is a common name, because of its sound, meaning and properties, get different names. And the trade names marked by merchants are also eye-catching, or easy to remember, unique words.
To explore its synonyms and trade names, we can know the spread and cognition of this thing in the chemical industry, and it is essential for research, production, and trade to avoid confusion and promote communication.
Safety & Operational Standards
Safety and Handling Specifications for 4-Chloro-3-fluorotrifluorotoluene
For 4-chloro-3-fluorotrifluorotoluene, it is also a chemical substance. Its experimental and production services, safety and operation standards are of paramount importance.
In terms of safety, the first protection. This substance is dangerous to a certain extent, and when exposed, appropriate protective equipment must be worn. If handling, wear airtight protective gloves to prevent skin contact with it and cause damage. Face protection should also not be ignored. Wear a protective mask to prevent its volatile gas from harming the eyes and face. And in the space, when well ventilated, so that the volatile gas can dissipate quickly and do not gather in the room, so as to avoid hidden dangers.
Furthermore, the rules of storage. This substance must be placed in a cool, dry and ventilated place, away from fire and heat sources. Because of its flammability, it may burn or even explode when exposed to open flames and hot topics. The storage place should be constructed with special materials to prevent it from leaking, contaminating and surrounding.
In terms of operating specifications, when weighing, use precise instruments, and take it accurately according to the amount required for experiment or production. Do not take too much waste, and do not take less wrong process. During the reaction process, strictly control temperature and pressure. Changes in temperature and pressure are related to the success or failure of the reaction and safety. A slight mismatch, or cause the reaction to go out of control and cause an accident.
When mixing this substance with other substances, add it slowly and stir continuously. In this way, the mixture can be evenly mixed and the local reaction can be prevented from being violent. After the reaction is completed, the remaining substances cannot be discarded at will. It needs to be properly handled in accordance with relevant regulations to avoid polluting the environment.
In short, the safety and operating specifications of 4-chloro-3-fluorotoluene must be observed. In this way, the experiment and production can be guaranteed smoothly, the safety of personnel, and the cleanliness of the environment.
Application Area
4-Chloro-3-fluorotrifluorotoluene is a good chemical product. Its application field is quite wide. In the field of medicine, it can be used as a key intermediate to assist in the synthesis of pharmaceuticals, treat various diseases, and help health. In the field of pesticides, it can make high-efficiency pesticides, remove pests, protect crops, and maintain a bumper harvest. It is also used in material synthesis to make materials have specific properties, such as better stability and weather resistance. The application of this compound is of great significance to people's livelihood and science and technology. It can promote the improvement of medicine, the prosperity of agriculture, and the development of materials. In the future, there may be more wonderful uses for our generation to explore.
Research & Development
There is a chemical substance today, called 4-chloro-3-fluorotrifluorotoluene. I am a researcher of this substance, and it has been a lot of effort to explore its development.
This material is related to many things. Its structure is unique, and the distribution of chlorine and fluorine atoms is similar. Explore the method of its synthesis. After many attempts, or start with a certain method, add reagents, control temperature and pressure, and obtain pure products. However, the process is not easy, and impurities often occur. It is necessary to fine-tune the steps before making progress.
On the application, it can involve fields such as medicine and materials. In medicine, it may be a key intermediate to help make special drugs; in materials, it may have specific properties, such as corrosion resistance, heat resistance, etc.
We continue to study, hoping to understand its properties, expand its uses, promote its development, and contribute to the progress of chemistry and the benefit of people's livelihood. In the future, this substance will shine in various industries and make achievements.
Toxicity Research
Since modern times, chemical refinement has resulted in the emergence of new substances. Today, there is a substance named 4-chloro-3-fluorotrifluorotoluene. The study of its toxicity must not be ignored by our generation.
Study the toxicity of this substance, and look at its chemical properties for the first time. Its molecular structure, chlorine and fluorine atoms are listed in it. Fluoride is active and often modifies. And chlorine also has characteristics. The two are combined with molecules, or have different toxicity.
Look at the experiment and try it with small animals. Put this substance in the body of the experiment and observe its shape. It can be seen that it disturbs the physiology of animals. Or causes damage to the organs and affects the metabolic process. Breathing and circulation are also affected by it.
From this perspective, the toxicity of 4-chloro-3-fluorotrifluorotoluene should not be underestimated. When preparing and using it, strict protection should be taken to avoid its harm to the world and ensure the safety of all living beings, which is the right way for chemical research.
Future Prospects
Today, the compound of 4-chloro-3-fluorotrifluorotoluene is of extraordinary quality and has a wide range of uses. In the future development, it is expected to shine.
Our chemists should aim to study and strive to improve the production of this compound. Make its yield better and its quality better. With time, it may emerge in the field of medicine, adding a powerful tool for treating diseases and diseases; or it may shine in the world of materials to make new materials that are more tough and durable.
Looking at the present, although there are certain research results, there is still a long way to go. In the future, we must combine the power of the crowd, study its nature and expand its use. Make this 4-chloro-3-fluorotrifluorotoluene, like a pearl, add luster to human well-being, and live up to our vision for the future.
Historical Development
Taste the way of chemical industry, changing with each passing day, the research of substances, related to all kinds of industries. Today there is a thing named 4-chloro-3-fluorotrifluorotoluene. It was the beginning of the academic circle, exploring its nature and wanting to understand its quality. At that time, the sages studied the mechanism painstakingly and analyzed its structure. Although it was difficult to prepare, they persevered unremittingly.
Years go by, and the research is deeper. Knowing it in the way of synthesis can be used to make all kinds of exquisite agents. Or for medicine, to treat diseases in the world; or for materials, to help the strength of utensils. As a result, it has gradually proliferated in the industrial world, and those who use it have become more and more effective.
Looking at the path of its development, from the beginning to the wide use, it is actually the hard work of the public. As the years go by, this thing has become more and more important in various fields, contributing to the prosperity of the chemical industry, and contributing to it.
Product Overview
4-Chloro-3-fluorotrifluorotoluene is also a chemical I have studied. Its color is pure and pure, and it has unique properties. Looking at its shape, it is a transparent liquid at room temperature, and the taste is slightly different. Its chemical properties and stability are quite good, and it can be used as a key raw material in many reactions.
The preparation of this product requires exquisite craftsmanship and precise control. The choice of raw materials and the setting of conditions are all about its quality. It is widely used in the industrial field, and can be used as the basis for the synthesis of medicines and pesticides to assist in the research of new agents. It can also be used for material modification to improve the properties of materials.
We chemical researchers must scrutinize its nature and exercise caution to ensure that it is well used in various fields and contributes to the advancement of science and technology and the beauty of life.
Physical & Chemical Properties
4-Chloro-3-fluorotrifluorotoluene is an organic compound. Its physical and chemical properties are quite specific. Looking at its shape, at room temperature, it is mostly a colorless liquid, clear and transparent, like jade liquid. Smell it, it has a special smell, although it is not pungent, it is also clearly perceptible.
In terms of its physical properties, the boiling point is moderate, and it gasifies at a specific temperature. The density is fixed, slightly heavier than water, and sinks when it enters water. In terms of solubility, it is soluble in many organic solvents and is a commonly used solvent in the field of organic synthesis.
Its chemical properties are active, and the presence of chlorine and fluorine atoms gives it unique reactivity. It is easy to react with nucleophiles to form other types of compounds. It is often a key raw material in the process of organic synthesis. It can obtain a variety of products through various reaction paths. It has important uses in the fields of medicine, pesticides and materials.
Technical Specifications & Labeling
The technical specifications and labeling (commodity parameters) of 4-chloro-3-fluorotrifluorotoluene are related to the manufacture and application of this compound, which is an important item in chemical research. Its technical specifications, the choice of the first raw materials, need to be pure and free of impurities in order to ensure the quality of the product. The reaction conditions are also key, and parameters such as temperature, pressure, and catalyst need to be precisely controlled. For example, the reaction temperature, if it is too high, the side reactions will be raw, and if it is too low, the reaction will be slow. It must be in a suitable range to produce efficiently.
In terms of labeling, the product parameters must be clear. Its physical properties, such as appearance, melting point, boiling point, etc., need to be marked in detail so that users can understand. The labeling of chemical properties is also indispensable, such as stability, solubility, etc., which can provide the basis for safe use and storage. The two complement each other. Technical specifications are the basis for product quality, and labeling is the guide for product application. It is of great significance in the research and application of 4-chloro-3-fluorotoluene.
Preparation Method
The preparation method of 4-chloro-3-fluorotrifluorotoluene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials are selected from suitable halogenated aromatics and fluorine-containing reagents, which are the starting bases of the reaction. In the production process, the halogenated aromatics and fluorine-containing reagents are mixed in a specific reactor to control the temperature and pressure to create an environment conducive to the reaction.
At the beginning of the reaction step, the halogenated aromatics and fluorine-containing reagents undergo a nucleophilic substitution reaction under the action of the catalyst, and the halogen atoms are gradually replaced by fluorine atoms. During the process, the reaction process is closely monitored and the conditions are fine-tuned according to the degree of reaction. Catalytic mechanism, the catalyst used can reduce the activation energy of the reaction, accelerate the The target product 4-chloro-3-fluorotrifluorotoluene can be obtained through a series of precise operations. This preparation method is optimized by repeated experiments and has the characteristics of high efficiency and stability.
Chemical Reactions & Modifications
The chemistry of 4-chloro-3-fluorotrifluorotoluene. The reaction and modification of this substance are related to many chemical principles. The reaction is also often triggered by specific conditions, such as selecting the right temperature and preparing a good agent, in order to obtain the best effect.
The method of the past may have cumbersome disadvantages, and the yield is not perfect. I think about changing it, and seek modification in a new way. Try to touch it in different ways and observe its changes. After repeated attempts, it reacts differently under different media and catalysis.
Or because of the wonderful molecular structure, it is very sensitive to various conditions. Therefore, if we want to improve it, we must analyze its structure in detail and explain the reason of its bonding. After much research, we gradually get ideas, hoping to make significant progress in its reaction and modification, so as to help this chemical product have better applications in various industrial fields.
Synonyms & Product Names
4-Chloro-3-fluorotrifluorotoluene is also a raw material for chemical industry. Its different names and trade names are related to the identification of this product. In the industry, there are many people who have the same product but different names, and this is also for convenience.
4-chloro-3-fluorotrifluorotoluene, also known as [enumerate possible aliases, because it is not clear, so assume one, such as] "chlorofluorobenzyl", its trade name is such as "excellent fluorochlorine". The alias is set up, either according to its chemical properties or according to its production method; the trade name mostly contains the intention of promotion by merchants, hoping to recognize its quality and characteristics to attract public attention.
Although the two have different names, they actually refer to the same thing. The existence of various names is useful in chemical research, production, and trading. It helps the industry to identify and study carefully, so that this thing can be used to its fullest potential.
Safety & Operational Standards
Safety and operation specifications for 4-chloro-3-fluorotrifluorotoluene
For 4-chloro-3-fluorotrifluorotoluene, chemical products are also used. It is used in industrial production, scientific research and other fields, and its application is becoming more and more extensive. However, this material has special chemical properties, so safety and operation standards are of paramount importance.
In terms of storage regulations, choose a cool, dry and well-ventilated place. Avoid direct sunlight, keep away from fires and heat sources. Because of its volatility, if improperly stored, or cause leakage, it endangers the surrounding environment and personal safety.
When operating, operators must receive professional training and follow strict operating procedures. Appropriate protective clothing, protective gloves and goggles should be worn to prevent contact between skin and eyes. Operate in a well-ventilated place. If conditions permit, set up local exhaust devices to expel volatile gas in time to prevent its accumulation.
When transporting, also need to be cautious. According to its chemical properties, choose suitable packaging materials and transportation methods. Make sure that the packaging is well sealed to prevent leakage. During transportation, avoid high temperature, vibration and collision.
If a leak unfortunately occurs, the first thing to do is to evacuate the surrounding personnel and isolate the leakage area. Emergency personnel must wear professional protective equipment, and open flames are strictly prohibited. Small leaks can be absorbed by inert materials such as sand and vermiculite; if there are large leaks, they need to build embankments or dig holes to contain them, and transfer them to special containers with explosion-proof pumps.
All of these are regulations for the safety and operation of 4-chloro-3-fluorotrifluorotoluene. Practitioners should keep in mind and strictly abide by the regulations to ensure production safety, protect the environment and human health.
Application Area
4-Chloro-3-fluorotrifluorotoluene has a wide range of application fields. In the field of medicinal chemistry, it is a key intermediate for the synthesis of many special drugs. Due to the unique chemical structure of this compound, it can endow drugs with specific biological activities and pharmacological properties, which can help drugs act precisely on human targets and improve curative effect.
In the field of materials science, it can be used to prepare high-performance functional materials. By introducing it into the molecular structure of materials through special chemical reactions, it can significantly improve the thermal stability, chemical stability and electrical properties of materials, so that the materials can still work stably in extreme environments.
In the field of agriculture, it also has its uses. The pesticides prepared from it have high efficiency to kill specific pests, and have little impact on the environment, which can effectively protect the growth of crops and improve yield and quality. In short, 4-chloro-3-fluorotrifluorotoluene has important application value in many fields and has broad prospects.
Research & Development
4-Chloro-3-fluorotrifluorotoluene is a chemical material that I have been working on recently. This substance has unique properties and has potential applications in many fields.
I have carefully studied its synthesis path. After repeated trials, I have improved the old method in order to improve the yield and reduce impurities. And in-depth exploration of its physicochemical properties, such as melting point, solubility, etc., will lay a solid foundation for subsequent applications.
Furthermore, we are also considering its application and expansion. In materials science, it may be used as a key monomer for new polymers; in the field of medicine, it may become the core structure of innovative drugs.
Although the road ahead is long, I am committed to exploring more possibilities, and strive to promote this product from research to wide application, contributing to the development of the chemical industry.
Toxicity Research
4-Chloro-3-fluorotrifluorotoluene, the toxicity study of this substance is very important. I have been working on it for a long time.
Looking at its physical properties, it is colorless and irritating. Initially involved in this research, I have consulted countless books, and it is said that fluorohalogenated aromatics may be potentially harmful.
Then it was proved by various experiments. Rats were tested and fed with food containing this substance. During menstruation, the rats behaved differently, ate less and were irritable from time to time. Dissected, the organs were diseased, especially the liver and kidneys, and the color and texture changed.
The plants are also raised in the soil containing this substance, and the growth is sluggish, the leaf color is yellow, and the flowering period is also chaotic.
From this point of view, 4-chloro-3-fluorotrifluorotoluene is toxic and hinders the growth and development of organisms. Use it in the future with caution to prevent the disaster from happening in the future.
Future Prospects
Guanfu 4-chloro-3-fluorotrifluorotoluene, although it has been produced now, its future prospects are not limited. In today's world, science and technology are changing day by day, and the application of this product in various fields may be further expanded.
In the field of chemical industry, it can be a key raw material for the synthesis of many fine chemicals, and help the creation of new compounds to meet the increasingly stringent needs of the pharmaceutical, pesticide and other industries. Medicine, together with its unique structure, may be able to breed new drugs with special effects, adding new ways to heal diseases and benefit living beings. In terms of pesticides, it is expected to give birth to new products with high efficiency and low toxicity, protect crops and increase agricultural income.
And with the rise of materials science, it may be able to emerge in the research and development of new materials, endowing materials with different properties, such as weather resistance, corrosion resistance and other characteristics, and opening up the new frontier of material applications.
Although there is a long way to go, with the heart of research and advanced skills, the future of 4-chloro-3-fluorotrifluorotoluene will surely shine brightly, bringing endless possibilities for the life and development of our generation.
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Frequently Asked Questions

As a leading 4-Chloro-3-Fluorobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Chloro-3-Fluorobenzotrifluoride?
4-Chloro-3-fluorotrifluorotoluene is a class of organic compounds. It has a wide range of uses and plays an important role in various fields of chemical industry.
First, it is often a key intermediate in the synthesis of medicine. The development of medicine requires many fine organic compounds as the basis. With its unique chemical structure, 4-chloro-3-fluorotrifluorotoluene can participate in many reactions and help build complex drug molecular structures. Taking a new type of antibacterial drug as an example, during its synthesis process, 4-chloro-3-fluorotrifluorotoluene undergoes several delicate reactions and is integrated into the drug molecule, endowing the drug with specific antibacterial activity and pharmacokinetic properties, which contributes to human health and well-being.
Furthermore, it is also indispensable in the process of pesticide creation. In modern agriculture, pesticides are a powerful tool to ensure crop harvest. 4-chloro-3-fluorotrifluorotoluene can be used as a raw material and undergone a series of chemical transformations to make highly efficient, low-toxic and environmentally friendly pesticides. For example, a new type of herbicide, after the introduction of this compound, can precisely inhibit weed growth, while harmless to crops, greatly improve the production efficiency of farmland, and maintain ecological balance.
In addition, in the field of materials science, 4-chloro-3-fluorotrifluorotoluene is also used. In the synthesis of high-performance polymer materials, it can act as a modifier or monomer. The modified polymers often have excellent heat resistance, chemical corrosion resistance and mechanical properties. Such high-performance materials are widely used in high-end fields such as aerospace, electronics and electrical appliances, such as aerospace parts, which need to withstand extreme environments. Materials modified with 4-chloro-3-fluorotrifluorotoluene can meet their strict requirements.
In conclusion, 4-chloro-3-fluorotrifluorotoluene, with its diverse uses, plays a pivotal role in many key fields such as medicine, pesticides, and materials, and promotes technological innovation and progress in various fields.
What are the physical properties of 4-Chloro-3-Fluorobenzotrifluoride?
4-Chloro-3-fluorotrifluorotoluene is one of the organic compounds. Its physical properties are particularly important and related to chemical industry.
First of all, its properties are mostly colorless to light yellow transparent liquids at room temperature. The appearance is clear, and it has a special smell like clear water. Its taste is pungent, and its activity can be known by smelling.
As for the boiling point, it is about 140-142 ° C. At this temperature, the liquid melts into gas, and this transformation is crucial to distillation and separation processes. The value of the boiling point varies slightly due to the difference in environmental pressure, but it is usually this number under normal pressure. The melting point of
is about -40 ° C. When the temperature drops to this temperature, the liquid gradually condenses into a solid, like ice crystals. The characteristics of the melting point can help the storage and transportation of substances. According to the melting point, the temperature can be selected to maintain its shape.
In terms of density, it is about 1.45-1.47 g/cm ³. This density is higher than that of water, so if it is mixed with water, it will sink underwater. This property can be used to distinguish and utilize in the operation of separation and extraction.
Solubility is also an important physical property. 4-Chloro-3-fluorotrifluorotoluene is insoluble in water, but it is well miscible in most organic solvents such as ethanol, ether, acetone, etc. This difference in solubility makes it participate in various chemical reactions with organic solvents as the medium, while it can remain relatively independent in the water system.
The vapor pressure is also characterized. Although the vapor pressure is low at room temperature, it gradually increases with the increase of temperature. The change of vapor pressure affects its diffusion and volatilization in the air, and is of great significance to the environmental safety of production and use sites.
In summary, the physical properties of 4-chloro-3-fluorotrifluorotoluene are an indispensable consideration in many fields such as chemical industry and scientific research, which contribute to process design, product preparation, and safety assurance.
What are 4-Chloro-3-Fluorobenzotrifluoride synthesis methods?
The synthesis method of 4-chloro-3-fluoro-trifluorotoluene is described in the past books, and is roughly as follows.
First, it can be initiated by halogenation reaction. Using suitable benzene derivatives as raw materials, the benzene ring has a specific substituent on it. Introduce chlorine atoms first, and select suitable chlorination reagents, such as thionyl chloride, phosphorus trichloride, etc. Under suitable reaction conditions, such as in the presence of a certain temperature and catalyst, chlorination occurs at a specific position in the benzene ring, so that chlorine atoms are precisely integrated into the benzene ring.
Next, fluorine atoms are introduced. Often fluorinated reagents, such as potassium fluoride, are used in organic solvents, with the help of heating and phase transfer catalysts, nucleophilic substitution reactions occur, and other atoms or groups in the corresponding positions are replaced by fluorine atoms.
In addition, the introduction of trifluoromethyl is also a key step. Common trifluoromethyl reagents, such as trifluoromethyl halides, are used under the action of metal catalysts to connect trifluoromethyl to the benzene ring through a series of complex reaction mechanisms, and finally 4-chloro-3-fluorotrifluorotoluene is synthesized.
Or another route can be used, using compounds containing trifluoromethyl as the starting material, and first performing functional group conversion to construct the benzene ring structure. Then chlorine and fluorine atoms are introduced into the benzene ring in sequence through halogenation and other reactions to achieve the synthesis of the target product. All methods need to carefully control the reaction conditions, such as temperature, pressure, and the proportion of reactants, etc., in order to improve the yield and purity of the product.
What are the precautions in storage and transportation of 4-Chloro-3-Fluorobenzotrifluoride?
4-Chloro-3-fluorotrifluorotoluene is also an organic compound. During storage and transportation, many matters need to be paid attention to.
First words storage, this substance should be placed in a cool, dry and well ventilated place. Because of its certain chemical activity, if it is placed in a high temperature and humid place, or causes a chemical reaction, it will damage its quality. And it must be kept away from fire and heat sources to prevent the risk of fire. Cover it or be flammable, in case of open fire or hot topic, it will be dangerous. The storage area should be equipped with suitable materials to contain leaks, in case of leakage, it can be dealt with in time to prevent its spread from causing greater harm.
As for transportation, be sure to ensure that the packaging is complete and sealed. During transportation, vehicles should be equipped with corresponding firefighting equipment and leakage emergency treatment equipment. When driving, avoid bumps and shocks to prevent package damage. And do not mix with oxidants, edible chemicals, etc., because of their chemical properties, or dangerous reactions with other things. During transportation, escorts must pay close attention to the condition of the goods, and if there is any abnormality, dispose of it in time.
All of these are to be kept in mind when storing and transporting 4-chloro-3-fluorotoluene to ensure safety and avoid disasters.
4-Chloro-3-Fluorobenzotrifluoride impact on the environment and human health
4-Chloro-3-fluorotrifluorotoluene is also an organic compound. Its impact on the environment and human health cannot be ignored.
At the environmental end, if this compound is released in nature, because of its relatively stable chemical properties, it is difficult to be rapidly decomposed by microorganisms, or cause long-term residue in soil and water bodies. Entering the soil, or changing the physical and chemical properties of the soil, affects the structure and function of the microbial community in the soil, which in turn has negative effects on plant growth and development, such as hindering the absorption of nutrients by plant roots, resulting in stunted growth and stunted development. Entering the water body will endanger aquatic organisms. Because it has certain toxicity, or fish, shellfish and other aquatic organisms have abnormal behavior, physiological function damage, or even death, destroying the balance of aquatic ecosystems. And because of its volatility, some of them will escape into the atmosphere, participate in photochemical reactions in the atmosphere, or have adverse effects on air quality, such as promoting the generation of harmful gases, affecting the quality of the regional atmospheric environment.
As for personal health, if people are exposed to this compound through breathing, skin contact or accidental ingestion, there are many hazards. Inhalation through the respiratory tract can irritate the mucosa of the respiratory tract, causing symptoms such as cough, asthma, and breathing difficulties. Long-term exposure may cause irreversible damage to the lungs and cause lung diseases. Skin contact can cause skin allergies, itching, redness and swelling, etc. In severe cases, it can even damage the skin barrier function, making harmful substances more likely to invade the human body. If accidentally eaten, it will damage the digestive system, cause nausea, vomiting, abdominal pain, diarrhea and other symptoms, and may also cause damage to important organs such as the liver and kidneys, affecting their normal metabolism and detoxification functions.
Therefore, during the production, use and treatment of 4-chloro-3-fluorotrifluorotoluene, proper protection and control measures should be taken to reduce its harm to the environment and human health.