4-Carboxybenzotrifluoride

Duxiu Chemical

Specifications

HS Code	117809
Chemical Formula	C8H5F3O2
Molar Mass	190.12 g/mol
Appearance	Colorless to light yellow liquid
Boiling Point	228 - 230 °C
Melting Point	26 - 28 °C
Density	1.348 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in many organic solvents like ethanol, ether
Pka	3.66
Flash Point	101 °C
Refractive Index	1.457

As an accredited 4-Carboxybenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 4 - Carboxybenzotrifluoride packaged in a sealed, corrosion - resistant container.
Storage	4 - Carboxybenzotrifluoride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and incompatible substances like strong oxidizing agents. Store in tightly sealed containers to prevent moisture absorption and evaporation. Avoid storing near reactive chemicals to prevent potential chemical reactions.
Shipping	4 - Carboxybenzotrifluoride is shipped in accordance with strict chemical transport regulations. It's typically packed in specialized containers to prevent leakage and ensure safe transit, following all safety protocols for hazardous chemicals.

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General Information

Historical Development

4 - Carboxybenzotrifluoride is a special chemical substance. Looking back in the past, its research and development process is of great significance. At the beginning, scholars explored fluorinated compounds in depth, hoping to find unique properties. After long-term research, this compound has emerged.
At that time, scientific research conditions were limited, and experiments often encountered difficult obstacles. However, scholars adhered to their perseverance and tried it repeatedly. Many attempts failed to meet expectations due to impure raw materials or difficult to control reaction conditions. But with unremitting efforts, they gradually mastered the delicacy of its synthesis. From the initial rough attempt to the maturity of the process, the 4-Carboxybenzotrifluoride synthesis method was continuously optimized, paving the way for subsequent wide application and leaving a deep imprint on the development of the chemical field.

Product Overview

4-Carboxyl trifluorotoluene is also an organic compound. It has unique properties and a wide range of uses. The appearance of this substance may be colorless to slightly yellow liquid, with certain chemical activity.
In the chemical industry, 4-carboxyl trifluorotoluene is often an important synthetic raw material. Through delicate chemical reactions, many high-value derivatives can be prepared. With its carboxyl group and trifluoromethyl characteristics, it can participate in a variety of condensation and substitution reactions, and become a key intermediate required for medicine, pesticides and materials science.
In pharmaceutical research and development, it can help create special drugs, because trifluoromethyl can change the lipophilicity, metabolic stability and enhance the efficacy of compounds. In pesticide production, it can also use its unique structure to synthesize high-efficiency and low-toxicity pesticide products to protect crop growth. This compound is an indispensable material in the field of chemical industry and scientific research, with broad prospects. It will be further explored by our generation to develop its greater capabilities.

Physical & Chemical Properties

4 - Carboxybenzotrifluoride, it is also a matter of transformation. Its physical properties, often under normal conditions, are solid or liquid. Color or color, or light color. Its melting and boiling, due to the molecular action force, each has a fixed value. The value of melting, the molecular arrangement is low; the boiling is low, and the energy required to overcome the attractive force of the molecule.
Its chemical properties are active, and the presence of carboxyl groups makes it acidic, which can cause neutralization and the reaction of the raw phase. Because of trifluoromethyl, it is specialized, and in the synthesis, it can be an important element and a multi-reaction process, into various useful compounds. Therefore, the materiality of 4-Carboxybenzotrifluoride is important for chemical research and engineering.

Technical Specifications & Labeling

4-Carboxyltrifluorotoluene, the process specification and identification (product parameters) of this substance are extremely critical. The process specification needs to clarify the preparation process, from the selection of raw materials, when the pure product is obtained, to the control of reaction conditions, such as temperature, pressure, and catalyst dosage, must be accurately determined. During the reaction process, the stirring rate and reaction time also affect the quality of the product.
In terms of identification, the product parameters should be clearly displayed. Its purity must be identified with accurate data, and the impurity content must also be clearly listed. The description of the appearance, color and state should be accurate. And on the packaging, the warning label is indispensable. If it is corrosive, there should be a striking reminder to inform everyone to operate with caution and follow the specifications to ensure the safety and efficiency of the production and use of this product.

Preparation Method

The preparation method of 4-carboxyl trifluorotoluene is related to the raw materials and production process, reaction steps and catalytic mechanism, and is the key to chemical research. The selection of raw materials often starts with compounds containing specific groups, such as benzene rings and convertible groups. In the production process, precise temperature control, pressure and reaction time are required.
The initial reaction step involves the conversion of multiple groups. By using specific reagents and conditions, the molecular structure of the raw materials gradually converges to the target product. Such as nucleophilic substitution or addition reaction, fluorine-containing groups and carboxyl precursors are introduced. In terms of catalytic mechanism, or metal catalysts can be used to reduce the activation energy of the reaction and promote the efficient progress of the reaction. Metal ions coordinate with the reactants, change the distribution of electron clouds, and increase the activity of the reaction check point. After multiple steps of fine regulation of the reaction, 4-carboxytrifluorotoluene was finally obtained. This preparation method lays the foundation for the acquisition and application of this compound.

Chemical Reactions & Modifications

In today's study 4 - Carboxybenzotrifluoride, the modification of this substance is very important. In the modification of this substance, it is often necessary to explore its multi-function, its reverse route and the generated substance. In order to make its performance better, the modification method is indispensable.
can be used to intervene with specific catalysis, or to modify the degree of reversal and other components, hoping to introduce the subtle transformation of its chemical properties and achieve the purpose of modification. Modification, this substance may present a new appearance in terms of qualitative and solubility, and can be used in more domains and greater effectiveness. Unremitting research on the method of modification of this substance can promote the progress of this substance in various aspects such as engineering and scientific research.

Synonyms & Product Names

4-Carboxyl trifluorotoluene, the alias and trade name of this compound, is related to the importance of our chemical research. There are many aliases, or due to past research methods and characterization of properties. Trade names vary according to manufacturers, uses, and markets.
In the past, when chemistry was first developed, to explore this compound, researchers called it differently according to its characteristics and reactions. This is the source of the alias. In order to distinguish the product from the market, manufacturers will also create unique trade names.
If we explore its relevant literature, we see many titles. Or due to differences in regions and times, the title has changed. However, its essence refers to this 4-carboxyl trifluorotoluene. Understanding its aliases and trade names is of great benefit to our procurement, research, and communication, as well as to avoid misunderstandings due to differences in terms of titles and to promote chemical research.

Safety & Operational Standards

4 - Carboxybenzotrifluoride is a chemical substance. Regarding its safety and operating standards, it is necessary to explain in detail to ensure that everything goes smoothly, personnel are comfortable, and the environment is safe.
In the workshop where this substance is prepared, the first heavy space should be well ventilated. Sophisticated ventilation equipment must be set up to operate day and night, so that the indoor air is constant and the harmful air is difficult to gather. When preparing, the operator must wear protective gear. The protective clothing material must be able to resist the erosion of this chemical and not allow the skin to contact it. Goggles are also indispensable to prevent it from splashing into the eyes and causing damage to the eyes. In addition, the mask should also be selected with high filtration efficiency to prevent the inhalation of dust or volatile gas of this substance and ensure the safety of breathing.
In terms of operation specifications, use 4-Carboxybenzotrifluoride, when using precision measuring tools. Do not rely solely on speculation to prevent inaccurate dosage, reaction deviation, or danger. And when operating, the action should be slow and steady, do not spill this substance. If accidentally dumped, immediately clean it up according to regulations. First cover it with adsorbed substances to prevent it from spreading, then carefully collect it and dispose of it according to the method of harmful waste.
Storage of this substance is also subject to regulations. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Due to high temperature or open flame, it is easy to cause changes in this substance, or risk of combustion and explosion. In the storage place, a clear warning sign should be set up to indicate that it is a dangerous chemical, and non-related people should not enter.
If someone accidentally comes into contact with 4-Carboxybenzotrifluoride, first aid should be taken as soon as possible. If it touches the skin, rinse immediately with plenty of water, rinse gently with mild soap, and then rinse. If it enters the eye, rinse quickly with running water, and call for medical assistance. If it is inhaled by mistake, move quickly to a place with fresh air to promote smooth breathing. If breathing is abnormal, apply artificial respiration immediately and send it to the hospital urgently.
In short, the safety and operating standards of 4-Carboxybenzotrifluoride are of great significance, and the preparation, access and storage links must be strictly adhered to, and no slack can be made to ensure safety.

Application Area

4-Carboxyltrifluorotoluene has a wide range of application fields. In the field of medicine, it can be used as a key intermediate to help synthesize drugs with specific curative effects. With its unique chemical structure, it may enhance the affinity and efficacy of drugs to specific targets. In the field of materials science, it can be used to prepare polymer materials with special properties, such as improving the corrosion resistance and stability of materials, and giving materials more excellent quality. In fine chemicals, it can participate in the synthesis of high-value-added fine chemicals, such as special coatings, dyes, etc., with its chemical properties, giving products unique color, luster and durability. This compound has shown important value in many application fields and provides strong support for the development of related industries.

Research & Development

Today there are things that are said to be 4 - Carboxybenzotrifluoride, and we study them. This material is unique, and it is worth exploring in the field of chemical research.
Wu Cao first observed its structure, analyzed the shape of its atomic phase, and understood its essence. Then explore its response, try it in the midst of various transformations, observe its changes, and record its results.
After months of research, its properties have gradually become clear. It can be used to make special materials, and it can also be expected in the industry of medicine. Based on it, it may be able to make new agents and treat various diseases.
Thinking about the way to expand its production, looking for efficient ways to reduce its consumption and improve its production. I hope that it can be widely used in the future, adding brilliance to the chemical industry and being beneficial to people's livelihood. We will devote all our efforts to promoting the research and application of this material, so that it will be widely spread in the world, and the chemical industry will benefit everyone.

Toxicity Research

4 - Carboxybenzotrifluoride, it is also necessary to change things. Today, when it comes to the study of toxicity, observe its characteristics in detail, and hope to clarify the shadow of it on the matter.
To observe its shape, or to fix it, or to liquid it, but it does not change its shape, it is necessary to reduce its toxicity. First, consider the matter, and put it on the body of rats, rabbits, etc., to observe its physiology. Its food, activity, and weight, as well as.
It is also applied to plants, and its liquid is applied to seedlings, and its growth, germination, branches, flowers, etc. are all being observed.
From, we can know the toxicity of 4 - Carboxybenzotrifluoride. It may affect the health of the animal and its physiological order; it may also hinder its growth and nurture. Therefore, I am careful when I use it, and I must obey the rules to prevent it from harming the animal.

Future Prospects

4 - Carboxybenzotrifluoride, the things that are transformed are also. I study it, hoping that it will be developed in the future.
This material nature is special, and its use is not good. In the field of technology, or in the field of special effects, it can save the disease of life; in the world of materials, it can be made into a strange material, which is generally needed.
Today's science and technology are new, and research is unremitting. In the future, it may be possible to transform it, and expand its use in the world. Make it more and more difficult, so that the material can be used. Undeveloped, we can look forward to it. We must study physics, do our best to improve our ability, so that 4 - Carboxybenzotrifluoride can make it happen, and make it beneficial to the world. This is also my.

Where to Buy 4-Carboxybenzotrifluoride in China?

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Frequently Asked Questions

As a leading 4-Carboxybenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-carboxyltrifluorotoluene?

4-Carboxytriethylamine is mainly used in chemical engineering. This compound has important uses in a wide range of fields.
In the field of chemical engineering, 4-carboxytriethylamine can be used as a synthetic compound. Due to the use of carboxytriethylamine, it can be used for multiple reactions to assist in the construction of specific molecules. For example, in the synthesis of a certain chemical, 4-carboxytriethylamine can be used for the synthesis of biologically active chemical components, which can be used for specific interactions and pain effects.
In the field of materials science, it can be used for the modification of polymers. The activity of the carboxyl group can be reversed on the polymer, triethylamine is introduced, and the properties of the polymer are changed. For example, it increases the solubility of the polymer, improves its surface properties, etc. In this way, new materials with good properties can be obtained, which can be used for materials, adhesives, etc. In terms of materials, 4-carboxytriethylamine modified polymer materials can increase the adhesion of the polymer-based materials, and the weather resistance is also improved.
Furthermore, in the field of chemical analysis, 4-carboxytriethylamine can be used as a catalyst or a catalyst. Because of its acid resistance, it can determine the pH value of the solution, which is very important in some chemical reactions or analyses. As a result, it can be used to form specific molecules, improve its separation effect in liquid phase chromatography and other analytical methods, and help to more accurately determine the composition and content of the substance.
Therefore, 4-carboxytriethylamine plays an indispensable role in the field of technology, materials, chemical analysis, etc., and promotes the development of multiple technologies.

What are the physical properties of 4-carboxyltrifluorotoluene?

4-Carboxyltriethylenetetramine, which is an organic compound. Its physical properties are as follows:
Viewed, it is often in the state of white to light yellow crystalline powder, and has a soft luster in sunlight. Smell it, there is little odor, but it is close to the fine smell, or there is a very light odor, not pungent. Touch it, the powder is delicate, smooth to the touch, and has no rough feeling.
On solubility, in water, it is soluble, and when dissolved, there is no violent reaction, and the solution is clear. In common organic solvents, such as ethanol, it also has a certain solubility, and its solubility is lower than that of water. Its melting point is quite high, and when heated to a specific temperature, it begins to melt into a liquid state. During this process, there is no decomposition and discoloration, which shows that its thermal stability is still good.
As for the density, after weighing and measuring, it is similar to that of common organic solids. When placed in the palm of your hand, you can feel its texture is firm. And it has a certain degree of hygroscopicity. In a humid environment, it is easy to absorb water vapor from the air, resulting in a slightly moist surface.
Furthermore, its crystal structure is regular and orderly, and the molecular arrangement is orderly under the microscopic level. This structural property also has many effects on its physical properties, such as melting point and solubility.
The physical properties of this compound are of great significance in many fields, and are an indispensable reference for chemical production, scientific research experiments, etc.

Is the chemical property of 4-carboxyltrifluorotoluene stable?

The chemical properties of 4-carboxyl trifluoroacetyl aniline are quite stable. In this compound, the carboxyl group (-COOH) and the trifluoroacetyl group (CF 🥰 CO -) are co-linked to the structure of aniline.
The carboxyl group is acidic and can dissociate hydrogen ions under appropriate conditions. However, due to the strong electron-absorbing effect of the trifluoroacetyl group, the electron cloud density is biased towards this group, resulting in a decrease in the electron cloud density of the hydroxyl group in the carboxyl group, hydrogen atoms are more likely to leave, and the acidity is enhanced compared with the general carboxyl group. However, its acidic expression is also restricted by the environment, and the degree of dissociation varies in different solvent mediums. The existence of
trifluoroacetyl groups not only affects the acidity of the carboxyl group, but also endows the molecule with unique Trifluoromethyl (CF-) is a strong electron-absorbing group, which can enhance the molecular polarity and has a great impact on the solubility and stability of compounds. Its solubility in common organic solvents is good, and it is more compatible with the interaction between organic solvents due to the enhancement of polarity.
Furthermore, the structure of the benzene ring is a conjugated system with certain stability. The electron cloud is delocalized from the entire benzene ring, which reduces the energy of the molecule and stabilizes the structure. Although the substitution of carboxyl and trifluoroacetyl groups will disturb the distribution of the electron cloud of the benzene ring, the inherent stability of the benzene ring conjugated system can still be maintained.
In summary, 4-carboxyl trifluoroacetyl aniline, due to the interaction of carboxyl group, trifluoroacetyl group and benzene ring, the overall chemical properties are relatively stable, but under specific reaction conditions, each group can still exhibit corresponding chemical activity and participate in various chemical reactions, which is also the interest of organic chemistry research.

What are the preparation methods of 4-carboxyltrifluorotoluene?

4-Carboxyl-3-ethoxyacetophenone is an important intermediate commonly used in organic synthesis. Its preparation methods are various, and the following are common methods:
1. ** Fu-gram acylation reaction **: Using m-ethoxybenzoic acid as the starting material, it is first converted into acid chloride. This step can be done by reacting m-ethoxybenzoic acid with dichlorosulfoxide with chlorinated reagents such as sulfoxide to form m-ethoxybenzoyl chloride. Subsequently, in the presence of anhydrous aluminum trichloride and other Lewis acid catalysts, m-ethoxybenzoyl chloride undergoes Fu-gram acylation reaction with acetyl chloride. During the reaction, anhydrous aluminum trichloride interacts with acyl chloride to form a highly active electrophilic reagent, which then attacks the benzene ring and introduces an acetyl group at a specific position in the benzene ring to obtain 4-carboxyl-3-ethoxy acetophenone. Its reaction mechanism is clear, the conditions are easy to control, and it is widely used in the field of organic synthesis.
2. ** The halogenation reaction is combined with the nucleophilic substitution reaction **: The m-ethoxy benzene is first halogenated, and the halogenated reagent such as bromine or chlorine is used to introduce a halogen atom at a specific position in the benzene ring under suitable catalysts and reaction conditions to generate halogenated m-ethoxy benzene. Afterwards, through the nucleophilic substitution reaction, the enol negative ion of ethyl acetoacetate is used as the nucleophilic reagent to attack the carbon atom connected to the halogen atom of halogenated m-ethoxybenzene, and realize the construction of the carbon-carbon bond. Subsequent steps such as hydrolysis and decarboxylation can obtain the target product 4-carboxyl-3-ethoxyacetophenone. Although this method step is slightly complicated, it has good selectivity to the reaction check point and can effectively obtain the desired product.
3. ** Using phenolic compounds as the starting material **: Using m-ethoxyphenol as the starting material, the phenolic hydroxyl group is first protected to prevent it from participating in unnecessary reactions in subsequent reactions. The protective group can be selected from common methyl, benzyl, etc. Next, acetyl and carboxyl related structural fragments are introduced through acylation reactions or other carbon-carbon bond formation reactions similar to the above. Finally, the protective group of phenolic hydroxyl is removed to obtain 4-carboxyl-3-ethoxyacetophenone. This approach requires attention to the selection of protective groups and the optimization of deprotection conditions to ensure the smooth progress of the reaction and the purity of the product.

What is the price of 4-carboxyltrifluorotoluene in the market?

Since modern times, in the market, tetratrimethoxybenzene has been widely used. This is because tetratrimethoxybenzene has many important uses in many fields.
It can be used in the synthesis of raw materials, or has the effect of curing diseases; it can be used in the production of chemical products, or it can be used for its special properties. Add formulations for the purpose of improvement; in the field of chemical industry, it can also be used as a general chemical reaction, and the step of improvement.
However, it is not often used, and it is affected by many factors. First, the supply of raw materials is essential. If the amount of raw materials required for manufacturing is sufficient, the collection is convenient, and the price is low, the cost of tetramethyltrimethoxybenzene will also be reduced, and the market sales will naturally decrease. On the contrary, if raw materials are scarce, the cost will be greatly increased, and the sales price will also be higher.
Second, the demand of the market will also affect the main reason for the price. If a certain period of production, chemical products, chemical industries, etc., the demand for tetramethyltrimethoxybenzene will increase, and the supply will keep up, and its price will increase. On the contrary, if the demand is low, the supply will not be left, and the price will not fall.
Furthermore, the production technology of the industry cannot be ignored. If there is a new technology in the world, the efficiency of production can be greatly improved, the cost can be reduced, and it will be reflected on the market, which is easy.
In addition, tetratrimethoxybenzene is used in the market. It is affected by the ups and downs of raw material supply, market demand, and biotechnology.