4 Bromo 3 Fluorobenzotrifluoride
Fluoride

4-Bromo-3-Fluorobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

690063

Chemical Formula C7H3BrF4
Molar Mass 257.00
Appearance Colorless to light yellow liquid
Boiling Point 176 - 178 °C
Melting Point N/A
Density 1.719 g/mL at 25 °C
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Vapor Pressure N/A
Flash Point 62 °C
Refractive Index 1.454 - 1.456
Chemical Formula C7H3BrF4
Molecular Weight 243.00
Appearance Colorless to light yellow liquid
Boiling Point 183 - 184 °C
Density 1.732 g/cm³
Flash Point 71 °C
Solubility Insoluble in water, soluble in organic solvents
Refractive Index 1.464

As an accredited 4-Bromo-3-Fluorobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - Bromo - 3 - Fluorobenzotrifluoride packaged in a sealed, corrosion - resistant bottle.
Storage 4 - Bromo - 3 - Fluorobenzotrifluoride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to avoid potential reactions. Ensure the storage area has spill - containment measures in case of accidental release.
Shipping 4 - Bromo - 3 - Fluorobenzotrifluoride is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring secure transportation to prevent spills and environmental or safety risks.
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4-Bromo-3-Fluorobenzotrifluoride
General Information
Historical Development
4-Bromo-3-fluorotrifluorotoluene is an essential product of chemistry. The origin of its substance was occasionally discovered by beginners in the exploration of various compounds. At that time, the experimental method was still simple, and the research was also difficult.
With the passage of time, chemical technology has improved day by day. Many sages have studied the reaction conditions carefully, hoping for better output. Or adjust the temperature, or change the reagent, and study unremitting.
In recent times, science and technology have flourished and the instruments are sophisticated. The analysis of 4-bromo-3-fluorotrifluorotoluene has become more and more accurate. The way of synthesis has also become better, the yield has increased, and the quality has become better. In the fields of medicine and materials, it is of great use, contributing to the development of chemical industry and promising future.
Product Overview
4-Bromo-3-fluoro-trifluorotoluene is a unique chemical product. It may be a colorless liquid with a special gas. This product is widely used in the field of organic synthesis.
Looking at its structure, bromine, fluorine atoms and trifluoromethyl are combined on the benzene ring. Bromine atoms are active and can cause nucleophilic substitution reactions, allowing it to connect to other groups and expand its derivation path. The addition of fluorine atoms increases the stability and unique chemistry of molecules, which is beneficial in the creation of medicines and pesticides.
Trifluoromethyl has strong electronegativity, which changes the polarity and fat solubility of the molecule. When the drug is developed, it can help it cross the biofilm and increase the efficacy.
Synthesis of this product often requires exquisite methods to control the reaction conditions and obtain high-purity products. In the chemical industry, 4-bromo-3-fluorotrifluorotoluene is an important material, opening up a new path for scientific research and production, and assisting in chemical innovation.
Physical & Chemical Properties
4-Bromo-3-fluoro-trifluorotoluene is an organic compound. Its physical properties are colorless and transparent at room temperature, with a special odor. Its boiling point is quite high, about [X] ° C, due to the intermolecular force. The melting point is [X] ° C, reflecting the characteristics of its molecular arrangement.
On its chemical properties, the presence of halogen atoms makes the reaction active. The characteristics of bromine and fluorine make nucleophilic substitution prone. In alkali or in contact with nucleophilic reagents, bromine atoms or fluorine atoms can be substituted. In the reaction of aromatic hydrocarbons, due to the strong electron absorption of trifluoromethyl, the electron cloud density of the benzene ring changes, and the reaction check point and rate are also different. And because of its fluorine content, it has certain chemical stability and can maintain structural integrity in specific environments. The physical and chemical properties of this compound are also important in organic synthesis and other fields.
Technical Specifications & Labeling
4 - Bromo - 3 - Fluorobenzotrifluoride is an important chemical product. Its process specifications and identification (product parameters) are extremely critical. As far as process specifications are concerned, the temperature, pressure and ratio of reactants of the reaction need to be precisely controlled. If the temperature is too high or too low, the reaction can deviate from expectations, affecting the purity and yield of the product. The pressure also needs to be maintained in a specific range to ensure the smooth progress of the reaction.
In terms of product identification (parameters), purity should be the first indicator to measure its quality. High purity of 4 - Bromo - 3 - Fluorobenzotrifluoride can meet the needs of high-end applications. In addition, parameters such as appearance and density cannot be ignored. They need to be measured and labeled in strict accordance with established standards to ensure the stability of product quality and make it suitable for various practical needs in market applications.
Preparation Method
The method of preparing 4 - Bromo - 3 - Fluorobenzotrifluoride is related to the raw material and production process, reaction steps and catalytic mechanism.
The raw material should be selected to be pure and properly adapted. The production process must follow a rigorous process. First, a suitable agent is combined with the starting material according to a specific ratio. Under moderate temperature and pressure, the reaction is initiated. The reaction step is the activation of the starting material, which greatly increases its activity and makes it easy to react with others. Then, through the method of addition and substitution, it gradually becomes an intermediate product. Then adjust the conditions of the reaction to transform the intermediate product and approach the target product.
As for the catalytic mechanism, choose a high-efficiency catalyst, which can reduce the energy barrier of the reaction and speed up the reaction process. The catalyst and the reactants are in contact to form a viable intermediate, making the reaction easy. And in the whole reaction process, temperature control, pressure control, and time control are used to ensure that the reaction goes forward and obtain a high purity of 4-Bromo-3-Fluorobenzotrifluoride. In this way, the desired product can be prepared.
Chemical Reactions & Modifications
The chemical industry is changing with each passing day, and the research of compounds is related to various fields. Today there are 4 - Bromo - 3 - Fluorobenzotrifluoride this substance, which has attracted much attention in the field of chemistry.
Its chemical reaction is the key to chemical research. The initial reaction, or the survival rate is not up to expectations, and the yield is not high. The reason is that the poor reaction conditions, such as temperature, pressure, and the choice of catalyst, can affect the reaction process.
If you want to improve, you must study its mechanism. After repeated tests, if the temperature is adjusted to make molecular collisions more effective, the reaction rate may be increased; if the catalyst is optimized to enhance its activity, the yield is also expected to increase. The purity of raw materials and the control of reaction time are also key. Through this change, the reaction efficiency of 4-Bromo-3-Fluorobenzotrifluoride may be greatly improved, which will contribute to the development of related industries and make the chemical industry more smooth.
Synonyms & Product Names
Today there is a thing, the name 4 - Bromo 3 - Fluorobenzotrifluoride. The same name is also related to the business name of this thing. This thing is meaningful in the matter of our research and development.
The name of the husband is the same, so it is easy to make it known to others. The business name is related to the city's easy circulation, and the name of the thing is the same. 4 - Bromo 3 - The name of the same name of the Fluorobenzotrifluoride, or according to its nature or manufacture, all represent the characteristics of this thing. The business name is also related to its specificity, for the purpose of introducing and using it.
Those of us who study and research, the business name of the same name of this thing, is more elegant. Only by knowing the origin of its name and the origin of its nature can we make good use of it to promote the progress of transformation and gain the world.
Safety & Operational Standards
4 - Bromo - 3 - Fluorobenzotrifluoride is a chemical substance, and it is related to its safety and operation specifications. It is necessary to specify in detail.
Store this substance in a cool, dry and well-ventilated place. Avoid open fires and hot topics to prevent accidents. It should be stored in separate stores with oxidants and alkalis, etc., and must not be mixed to avoid the risk of chemical reactions. The storage container must be tightly sealed to prevent leakage.
As for the operation, make sure that the operator is professionally trained and familiar with the operation process. When operating, wear appropriate protective equipment, such as protective clothing, gloves, and a gas mask to protect your own safety. Emergency treatment equipment should be prepared on the operation site. If something happens, you can respond immediately.
If this material leaks, the first thing to do is to evacuate unrelated personnel to a safe place and set up warning signs. Emergency responders must wear professional protective equipment, and it is strictly forbidden to have open flames, static electricity, etc. at the leakage site. Small leaks can be absorbed by inert materials such as sand and vermiculite, and properly collected and disposed of. If there is a large amount of leakage, it is necessary to build a dike or dig a pit for containment, transfer it to a special collection container with an explosion-proof pump, and then properly dispose of it.
When handling this material, it is also necessary to be careful, pack and unload it lightly to prevent damage to packaging and containers. During transportation, ensure that the container does not leak, collapse, fall, or damage. Transportation vehicles should be equipped with corresponding types and quantities of fire-fighting equipment and leakage emergency treatment equipment.
In this way, strict adherence to safety and operating standards can ensure the safety of personnel and avoid environmental hazards when using 4-Bromo-3-Fluorobenzotrifluoride.
Application Area
Today, there is a compound called 4 - Bromo - 3 - Fluorobenzotrifluoride. This compound has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help the development of new drugs and fight difficult diseases. It is expected to bring good news to patients. In the field of materials science, it can optimize the properties of materials, enhance their stability and functionality, such as in the manufacture of high-performance electronic materials, and improve the performance of electronic devices. In agricultural chemistry, it can be used to create high-efficiency and low-toxicity pesticides, help crops resist pests and diseases, and ensure a bumper harvest of food. In short, 4 - Bromo - 3 - Fluorobenzotrifluoride has important value in many application fields, and is an indispensable chemical substance, which contributes greatly to the progress of various fields.
Research & Development
In modern times, chemistry has flourished, and it strives for excellence in the study of various compounds. Today, there are 4-Bromo-3-Fluorobenzotrifluoride this compound, and our generation has studied it in depth.
At the beginning, it was difficult to synthesize this compound. After several experiments, I tried various paths. Or change the conditions of the reaction, adjust the temperature and pressure, and observe its changes; or the ratio of easy reactants, observe its effectiveness.
When researching, also consider the characteristics of this substance. Study its physical properties, such as melting point and solubility, to understand its state in different environments. More explore its chemical activity, meet with various reagents, and see how it responds to it, hoping to expand its use.
As for development, if the synthesis method can be optimized, its cost can be reduced, and its yield can be increased, it can be widely used in various fields. Or for medicine, to help the production of new drugs; or for materials, to add luster to the research of high-tech materials. With time and unremitting research, it will definitely add to the development of chemistry and shine.
Toxicity Research
The distinction between tasting and smelling material properties is related to the safety of the people. Now View 4 - Bromo - 3 - Fluorobenzotrifluoride This thing, the investigation of its toxicity cannot be ignored.
The husband of this thing is a new chemical product, or involved in industrial use. However, the signs of toxicity, at the beginning of observation, its qi may be irritating, and entering the body may injure the lungs and disturb qi and blood. Tested by ancient methods, if it touches the skin, it may cause redness, swelling and itching; if taken by mistake, the viscera will violate the harmony, and even endanger life.
Although today's technology is new, the study of its toxicity still needs to be reviewed in detail. It is necessary to observe its changes in different environments, examine its integration with other things, explore the details, and understand the reason for its poisoning, so as to prevent problems before they occur, ensure the well-being of everyone, and make this thing useful, avoid its harm and promote its benefits.
Future Prospects
Today there is a thing named 4 - Bromo 3 - Fluorobenzotrifluoride. We study it, and we feel that it has great potential for the future. This thing has unique properties and can be used in various new ways.
Looking at the current trend, the field of chemistry is changing with each passing day. The properties of this substance are expected to lead to the birth of new materials. In electronic devices, it may improve performance, making it more delicate and efficient.
In pharmaceutical research and development, there are also potential opportunities. Or with its unique structure, new drugs can be created, opening up new paths for the healing of diseases.
Although the current understanding is still shallow, I firmly believe that with time, through in-depth research, we will be able to understand more of its mysteries. In the future, it may be like a shining star, shining in the sky of chemical applications, contributing to human well-being.
Historical Development
4 - Bromo - 3 - Fluorobenzotrifluoride is an important compound in organic chemistry. Tracing its historical development, organic synthesis technology was still in its infancy. At that time, chemists explored the synthesis of various fluorine-containing and bromine-containing aromatic compounds. For this compound, it could only be prepared by complicated and inefficient processes in the early days. However, with the passage of time, chemical theory and technology have made significant progress. New catalysts and new reaction paths continue to emerge, the efficiency of synthesizing 4 - Bromo - 3 - Fluorobenzotrifluoride has been greatly improved, and the purity has also made a qualitative leap. Today, it is widely used in medicine, materials and other fields, helping the industry to reach new heights. Its development process has witnessed continuous progress and innovation in the field of chemical synthesis.
Product Overview
4-Bromo-3-fluoro-trifluorotoluene is also an organic compound. It may be a colorless liquid with a special odor. This compound has a wide range of uses in the field of organic synthesis. In its molecular structure, the ingenious combination of bromine, fluorine atoms and trifluoromethyl gives it unique chemical properties.
Bromine atoms are active and can participate in various reactions such as nucleophilic substitution, providing an opportunity for the construction of new carbon-heteroatom bonds; fluorine atoms have strong electronegativity, which can change the polarity and lipid solubility of compounds. The introduction of trifluoromethyl also significantly affects the stability and reactivity of molecules.
In many fields such as pharmaceutical chemistry and materials science, 4-bromo-3-fluorotrifluorotoluene is a key intermediate, which helps to synthesize many new compounds with special properties. The prospect is broad, and it needs to be further explored and developed by researchers.
Physical & Chemical Properties
4 - Bromo - 3 - Fluorobenzotrifluoride is an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, it is mostly liquid, with clear color and different taste. Its boiling point and melting point are fixed, and the boiling point is within a certain range, which is determined by the force between molecules. The melting point also has a fixed value according to its molecular structure and interaction.
In terms of its chemical properties, it is active because it contains halogen atoms such as bromine and fluorine. Bromine atoms can participate in nucleophilic substitution reactions. Although fluorine atoms have strong electronegativity, which gives molecules a unique electron cloud distribution, they can also promote or participate in various reactions under specific conditions. In the field of organic synthesis, it is often a key raw material due to its unique physical and chemical properties, assisting in the synthesis of many complex compounds.
Technical Specifications & Labeling
Today there is a product, named 4 - Bromo - 3 - Fluorobenzotrifluoride. Its process specification and identification (product parameters) are crucial to the quality and use of this product.
The person who specifies the process is the method of making this product. From the selection of raw materials, it must be carefully selected, and impurities must be removed to ensure its purity. As for the method of synthesis, when the temperature and speed are controlled according to precise steps, it is not good. When reacting, or in a closed device, or in a catalyst, there are rules to get the best effect.
The logo (product parameters) cannot be ignored. Mark its ingredients to make clear its chemical structure; remember its purity to prove the excellence of quality; book its properties, such as color, taste, and state, at a glance. In this way, the user knows the details and can make good use of it. This process specification and identification (product parameters) are the root of this thing, and it is related to its success and destruction, which cannot be ignored.
Preparation Method
This 4 - Bromo - 3 - Fluorobenzotrifluoride product needs to be prepared in detail. The raw materials and the production process are fundamental, the reaction step is the key, and the catalytic mechanism should not be underestimated.
To make this product, prepare suitable raw materials first. Select high-purity starting materials to ensure the quality of the product. The production process needs to be carefully planned, and each step must be precisely controlled.
In the reaction steps, proceed in sequence. The reaction conditions of each step, such as temperature, pressure, reaction time, etc., must be accurate. If the temperature is too high or too low, the reaction deviation can be caused, which affects the yield and purity of the product.
The catalytic mechanism is also the focus. Selecting an efficient catalyst can promote the reaction rate and improve the production efficiency. The amount of catalyst, activity maintenance, etc. need to be carefully studied.
In this way, from the selection of raw materials, to the process design, to the control of the reaction steps, and the study of the catalytic mechanism, 4 - Bromo - 3 - Fluorobenzotrifluoride an excellent preparation method.
Chemical Reactions & Modifications
Today there is a product, named 4 - Bromo - 3 - Fluorobenzotrifluoride. In the field of chemistry, its reaction and modification are the focus of our research.
The reaction of chemistry, such as the symmetry of yin and yang, changes without reason. The reaction of this substance, or the combination with other substances, or its own decomposition, all depend on environmental conditions, such as temperature, pressure, and catalyst. The way to modify it is to make it have better properties, such as stability and activity changes.
We explore its reaction mechanism, such as twisting and stripping cocoons, and hope to understand why. After repeated tests, we observe its changes in different situations, hoping to optimize its reaction path, improve its yield, and improve its performance. Make this substance more useful in various fields of industry and scientific research, so as to benefit the world.
Synonyms & Product Names
4 - Bromo - 3 - Fluorobenzotrifluoride This substance, in the field of my chemical research, has many synonymous names and commodity names. Its synonymous names, or based on its chemical structure properties, derive different expressions from its atomic combination and chemical bonding.
The name of the commodity often varies according to the marketing and application scenarios of the merchant. Or because it performs well in a certain type of synthetic reaction, it is named after the word that highlights the characteristic; or because it is suitable for a specific industry, it is named after the needs and habits of the industry.
For our generation of chemical researchers, it is essential to be familiar with its synonymous names and commodity names. This allows us to accurately retrieve literature, communicate and discuss smoothly, and avoid many errors and inconveniences on the road to scientific research, so as to achieve a deeper level of chemical research, explore the mysteries of matter, and promote progress in the field of chemistry.
Safety & Operational Standards
4 - Bromo - 3 - Fluorobenzotrifluoride is an important chemical substance. Safety and operating standards are of paramount importance in experiments and production.
When handling this substance, the experimenter must first wear complete protective gear. Wear dense protective clothing to protect against possible spills; wear tough protective gloves to avoid direct contact; wear a clear protective mask to prevent aerosol damage to the eyes. And the operation should be in a well-ventilated place, or in a fume hood, so that the volatile gas can be dispersed in time to avoid accumulation and risk.
It should also be stored with caution. It should be placed in a cool, dry place away from fire sources, separate from oxidizing and reducing substances to prevent accidental reactions. The storage device must be well sealed and marked with a clear logo, clearly indicating the ingredients, hazards and other information.
When using the operation, the action should be stable and accurate. Measure with clean and suitable equipment to avoid spills. If there is any spill, clean it immediately according to the specific process. Cover it with an inert adsorption material, collect it carefully, and then treat the residue with appropriate reagents to ensure environmental safety.
If you accidentally come into contact with this object, it will be handled differently according to the different parts of the contact. If it comes into contact with the skin, rinse it with a lot of water quickly, then wash it with soap; if it enters the eyes, rinse it with flowing water urgently, and seek medical treatment; if you inhale, go to a fresh air quickly, and if you have breathing difficulties, give oxygen and seek medical first aid.
During the operation, the experimenter should strictly follow the procedures and must not change it. Every step must be accurate and always alert to potential hazards. Regularly check the protective equipment and operating environment to ensure safety. In this way, the safety of people and the environment can be guaranteed when using 4-Bromo-3-Fluorobenzotrifluoride.
Application Area
4-Bromo-3-fluorotrifluorotoluene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediary. Physicians make special drugs, often rely on this. Because of its special structure, it can precisely interact with molecules in the biological body, so it can participate in the construction of active ingredients of drugs and help heal diseases.
In the field of materials science, it also has its place. It can be used to create materials with special properties, such as those with excellent weather resistance and chemical resistance. Craftsman-made high-end equipment and protective materials are often used to improve quality. In chemical reactions, it shows unique activity, can guide the reaction in a specific direction, and open up many paths for the synthesis of new substances. Therefore, 4-bromo-3-fluorotrifluorotoluene plays an important role in many application fields such as medicine and materials.
Research & Development
Today there are chemical substances 4 - Bromo - 3 - Fluorobenzotrifluoride, and we have explored them as chemical researchers. This substance has unique characteristics and is of great research value in the field of scientific research.
We have carefully investigated its structure, analyzed its reaction mechanism, and strived to clarify its chemical properties and potential uses. After repeated experiments and analysis, we have gradually understood its activity in specific reactions, which can provide an opportunity for the synthesis of novel compounds.
Although the research path has encountered many difficulties, such as harsh reaction conditions and complicated product separation, we have worked tirelessly to improve the method and optimize the process. With the aim of in-depth investigation, we will promote the application and expansion of this substance in materials science, drug research and development, and achieve a leap from basic research to practical application, contributing to scientific research progress and social development.
Toxicity Research
In recent times, chemistry has been refined, and new things have emerged in large numbers. Today, there is a product named 4-Bromo-3-Fluorobenzotrifluoride. In my chemical research, the investigation of its toxicity is crucial.
Examine this product in detail, its molecular structure is unique, and bromine, fluorine and other atoms are listed among them. To know its toxicity, it is necessary to observe its interaction with biological systems. Or at the cellular level, observe its impact on cell proliferation and metabolism; or in animal experiments, explore its effect on the function of the body's organs.
In the past, the study of poisons was often misjudged due to incomplete cognition. Today, we should study this product with caution and meticulous methods. Multi-party testing and comprehensive evaluation are expected to clarify the true appearance of its toxicity, providing evidence for future applications, protection, and other things, so as to avoid repeating the same mistakes, so that this substance can be used to its advantage, and to protect all living beings from its poison.
Future Prospects
Wuguan 4 - Bromo - 3 - Fluorobenzotrifluoride This thing is unique and promising in the field of chemical industry. Although there is still unfinished business in the current research, the future development can be expected.
The quality of this thing may be used in the production of new materials, which has extraordinary uses. Scientific researchers study day and night, hoping to make the best of its potential. In the future, it may be seen in medicine, electronics and other industries, shining brightly.
Although there may be thorns in the road ahead, with the wisdom of today's people and unremitting efforts, it will be able to overcome all kinds of difficulties. 4 - Bromo - 3 - The future of Fluorobenzotrifluoride will be like the rising sun, shining brightly, opening up a new world for our generation and achieving extraordinary business.
Where to Buy 4-Bromo-3-Fluorobenzotrifluoride in China?
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Frequently Asked Questions

As a leading 4-Bromo-3-Fluorobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Bromo-3-Fluorobenzotrifluoride?
4-Bromo-3-fluorotrifluorotoluene is an important chemical substance in the field of organic synthesis. Its main uses involve a wide range of aspects.
First, in the field of pharmaceutical synthesis, this compound is often used as a key intermediate. Due to the special structure of fluorine, bromine and trifluoromethyl, it is endowed with unique chemical and physical properties. It can participate in a variety of organic reactions and help build complex drug molecular structures. Through specific reaction steps, it can be cleverly combined with other organic reagents to lay the foundation for the creation of drugs with specific pharmacological activities, such as the development of new antibacterial, antiviral or anti-tumor drugs.
Second, in the field of pesticides, 4-bromo-3-fluorotrifluorotoluene also has significant functions. Due to its structural properties, it can be used as a key starting material for the synthesis of high-efficiency pesticides. After a series of chemical reactions, pesticide varieties with high selectivity, strong lethality and environmental friendliness to pests can be prepared, providing powerful means for agricultural pest control and ensuring crop yield and quality.
Third, in the field of materials science, this compound has also emerged. It can be used to synthesize polymer materials with special properties, such as fluoropolymers. Due to the presence of fluorine atoms, which can improve the chemical stability, weather resistance and low surface energy of materials, it has potential applications in coatings, plastics and other fields, and can prepare protective coatings or special plastic products with excellent performance.
Fourth, in the research process of organic synthetic chemistry, 4-bromo-3-fluorotrifluorotoluene is often used to explore and develop novel organic reaction mechanisms and methods. Chemists use in-depth research on its participation in reactions to expand organic synthesis strategies and promote the continuous progress and development of organic chemistry.
From this perspective, 4-bromo-3-fluorotrifluorotoluene plays an indispensable role in many fields such as medicine, pesticides, materials, and organic synthetic chemistry, and is of great significance to the development of related industries.
What are the physical properties of 4-Bromo-3-Fluorobenzotrifluoride?
4-Bromo-3-fluorotrifluorotoluene, an organic compound, is widely used in the chemical industry and scientific research. Its physical properties are unique and detailed as follows:
1. ** Properties **: Under normal conditions, 4-bromo-3-fluorotrifluorotoluene is mostly colorless to light yellow transparent liquid, with a pure appearance and no visible impurities. Under light and room temperature conditions, this morphology is stable and easy to store and use.
2. ** Melting point and boiling point **: The melting point is about -25 ° C, and the boiling point is about 178-180 ° C. The melting point is low, causing it to be liquid at room temperature, while the boiling point indicates that it needs to be heated to nearly 180 ° C to vaporize, which is of great significance in the separation and purification process.
3. ** Density **: The density is about 1.71g/cm ³, which is heavier than water. If mixed with water, it will sink to the bottom. This property is crucial when it comes to liquid-liquid separation operations.
4. ** Solubility **: Slightly soluble in water, but can be miscible with most organic solvents such as ethanol, ether, acetone, etc. This solubility characteristic makes it possible to choose a suitable organic solvent as a reaction medium according to different reaction requirements in organic synthesis to facilitate the reaction.
5. ** Vapor Pressure and Volatility **: At a certain temperature, with a specific vapor pressure, although the volatility is relatively not strong, in a poorly ventilated environment, part of it will still evaporate into the air after long-term exposure. When using, pay attention to operating in a well-ventilated place to ensure safety.
6. ** Refractive Index **: The refractive index is about 1.454 - 1.456 (20 ° C). As a material characteristic constant, the refractive index can be used to identify the purity and concentration of substances, which is indispensable in quality control and analysis and testing.
Is 4-Bromo-3-Fluorobenzotrifluoride chemically stable?
4-Bromo-3-fluorotrifluorotoluene, its chemical properties are relatively stable. This compound contains halogen atoms such as bromine and fluorine, and has trifluoromethyl.
From the perspective of halogen atoms, bromine atoms are moderately active. Although they are not as prone to substitution reactions as some active halogenated hydrocarbons, under appropriate conditions, nucleophilic substitution can occur when encountering nucleophiles and suitable catalysts and reaction environments. For example, under the action of alkaline environments and specific phase transfer catalysts, hydroxyl and other nucleophilic testers can attack the check point of bromine atoms and achieve substitution. Due to the large electronegativity of fluorine atoms, it will have a significant impact on the electron cloud density of the benzene ring, causing the electron cloud of the benzene ring to shift towards the fluorine atom, which reduces the electrophilic substitution activity of the benzene ring.
Trifluoromethyl is a strong electron-absorbing group, which further reduces the electron cloud density of the benzene ring. This not only affects the substitution reaction activity on the benzene ring, but also enhances the overall stability of the molecule. Due to its strong electron-absorbing effect, the polarity of the molecule changes, which affects its solubility and other physical properties, and has better solubility in organic solvents.
Under normal conditions, 4-bromo-3-fluorotrifluorotoluene In general, in common organic reaction systems, without specific initiation conditions, this compound can maintain a relatively stable state and exhibit good chemical stability.
What are 4-Bromo-3-Fluorobenzotrifluoride synthesis methods?
There are many ways to synthesize 4-bromo-3-fluorotrifluorotoluene. One method is to use 3-fluoro-4-aminotrifluorotoluene as the starting material. First, it is placed in a low temperature environment with sodium nitrite and hydrobromic acid, and the diazotization reaction is carried out. This process needs to be carefully controlled to prevent side reactions. The diazonium salt is ready, so it interacts with cuprous bromide, and through Sandmeier reaction, 4-bromo-3-fluorotrifluorotoluene can be obtained.
Another method is to use 3-fluorotrifluorotoluene as the initial material. Make it and bromine in the presence of appropriate catalysts, such as iron powder or iron tribromide, electrophilic substitution reaction. Due to the localization effect of fluorine atoms, bromine atoms can be connected in ortho positions to obtain the target product. However, this reaction also needs to pay attention to the regulation of reaction conditions, such as temperature, reactant ratio, etc., to increase the purity and yield of the product.
Furthermore, bromine, fluorine and trifluoromethyl can be gradually introduced through multi-step reactions starting from aromatics containing appropriate substituents. Although this path is slightly complicated, it is also an effective method if the reaction conditions of each step are accurately determined. If an alkyl group is first introduced from aromatics and haloalkanes under a suitable catalyst, and then halogenated, fluorinated, and trifluoromethylated, 4-bromo-3-fluorotrifluorotoluene can be synthesized after ingenious design and careful operation. All these synthesis methods have their own advantages and disadvantages, and need to be carefully selected according to actual needs, such as the availability of raw materials, cost considerations, and product purity requirements.
What is the price range of 4-Bromo-3-Fluorobenzotrifluoride in the market?
The price of 4-bromo-3-fluorotrifluorotoluene in the market often varies for many reasons. Looking at the market conditions in the past, the price of this product may fluctuate between hundreds and thousands of yuan per kilogram.
The change in its price is primarily related to supply and demand. If there are many people who need it, but the quantity produced is small, the price will tend to rise; conversely, if the supply exceeds demand, the price may decline. Furthermore, the price of raw materials also has a great impact. If the price of raw materials required for the synthesis of this product increases, the production cost of this compound will also increase, and the price will increase; if the price of raw materials decreases, the price of the product may decrease.
Process and technology are also key. If there is a new and excellent synthesis method that can reduce costs and increase productivity, the price may change due to it. And the scale of production also affects the price. Large-scale production often reduces the unit cost due to economies of scale, and the price also follows.
The price varies from region to region. In different places, the price of the same product varies due to differences in logistics, taxation, and market competition. However, the exact price needs to be consulted with inter-market suppliers in detail, and the accurate price can only be determined according to the current market conditions, quantity and other factors.