4 Bormobenzotrifluoride
Fluoride
4-bormobenzotrifluoride
Chemical Formula C7H4BrF3
Molecular Weight 225.006
Appearance Colorless to light yellow liquid
Boiling Point 188 - 190 °C
Density 1.636 g/mL at 25 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point 75 °C
Refractive Index 1.475 - 1.477
FAQ

What are the main uses of 4-bromotrifluorotoluene?

The main users of 4-3 Sanjiang Jiayi Xin, their achievements are very good, and they are all helpful in all kinds of work.

In the Tao, its availability and efficiency. Different, the sex has cold, with 4-3 Sanjiang Jiayi Xin, it can make the quality and the effectiveness, or increase its effectiveness. In case of cold, with, together with the amount of this, it can promote the speed of the disease, remove the cold evil and calm the disease. In case of illness, Wu Qing, with its introduction, so that the disease can go straight into the disease, and bleed poison to relieve the disease.

In the matter of gold tools, it is also indispensable. Metallurgical gold, 4-Sanjiang Jiayesin can help melt the stone, making it easy to divide and improve the gold. For example, if you put this thing into the stone, it can make the stone melt faster, and the resulting metal has a high degree of fertility, and the soil can be used to make fine utensils. It is a sacrificial weapon, a weapon, or a daily use weapon. It is all improved because of the 4-Sanjiang Jiayesin.

Furthermore, the situation also benefits. The amount of 4-Sanjiang Jiayesin is applied to the field soil, which can fertilize the soil. It can improve the soil, make the soil sparse and transparent, and facilitate the extension of crop roots. And it can add nutrients in the soil, promote crop growth, make the seedlings grow, and the rice harvest can be harvested, and ensure the food supply of people's livelihood.

For printing and dyeing, 4-3 Sanjiang Jiayi Xin can be used to help dyeing. For cloth dyeing, adding this material can make the dye better adhere to the material, and the dyed color is long-lasting and not easy to fade. Dyeing workshops can use this to make exquisite materials for people's clothing and use.

Therefore, 4-3 Sanjiang Jiayi Xin plays an important role in many industries such as production, engineering, engineering, and agriculture, etc. It is also a good help for the production of materials and the prosperity of people's livelihood.

What are the physical properties of 4-bromotrifluorotoluene?

4-Bromotrifluorotoluene is a key raw material in organic synthesis. Its physical properties are as follows:

Under normal temperature and pressure, 4-bromotrifluorotoluene appears as a colorless to light yellow transparent liquid with a clear appearance and specific flow characteristics.

Smell its odor, which has a relatively unique and irritating odor, which can be used as one of the characteristics to distinguish the substance to a certain extent.

Measure its boiling point, which is about 155-157 ° C. At this temperature, the substance changes from liquid to gaseous state. This boiling point characteristic is of great significance in separation, purification and related reaction temperature control.

Measure its melting point, which is roughly -27 ° C. When the temperature drops below the melting point, the substance will solidify from liquid to solid. Knowing the melting point provides a basis for setting storage and transportation conditions.

Explore its density, which is about 1.72 g/cm ³, which is higher than the density of water. If mixed with water, it will sink to the bottom of the water. This density characteristic is important for operations such as phase separation involving the substance.

Check its solubility. 4-bromotrifluorotoluene is insoluble in water, but it can be miscible with most organic solvents such as ethanol, ether, acetone, etc. This difference in solubility provides an important reference for the selection of organic synthesis reaction systems and the separation and purification steps of products.

In addition, the physical properties of 4-bromotrifluorotoluene, such as vapor pressure and refractive index, also have their own specific values, which have a key impact on its application in chemical production, scientific research experiments, etc., and need to be accurately mastered and applied according to specific needs.

What are the chemical properties of 4-bromotrifluorotoluene?

4-Cyanotrifluorotoluene is a class of organic compounds. Its chemical properties are unique and have a variety of characteristics.

This substance contains a cyanide group (-CN) and a trifluoromethyl group (-CF). The cyanyl group has high activity and can participate in many reactions. If the cyanyl group can undergo hydrolysis reaction, under acidic or basic conditions, the cyanyl group is gradually converted into a carboxyl group (-COOH) to obtain a carboxyl group-containing compound. In organic synthesis, this reaction is often used to construct carboxyl-containing structures to prepare carboxylic acids, which are used in medicine, pesticides and other fields.

Trifluoromethyl has special properties because of its high electronegativity, which makes the molecule have a strong electron-absorbing effect. This effect affects the distribution of molecular electron clouds, resulting in a decrease in the density of carbon atom electron clouds linked to trifluoromethyl in 4-cyanotrifluorotoluene. In this way, some chemical bond activities in the compound change, and nucleophiles are more susceptible to attack. For example, in nucleophilic substitution reactions, the presence of trifluoromethyl makes the reaction activity different from that without the group, and may accelerate or change the reaction path.

4-cyanotrifluorotoluene can also be used as an important intermediate in the synthesis of many complex organic compounds. Its cyano groups and trifluoromethyl groups can be modified and transformed by different chemical reactions to construct organic molecules with diverse structures. In the field of materials science, polymers containing 4-cyanotrifluorotoluene structures may have special physical and chemical properties due to the presence of trifluoromethyl groups, such as chemical resistance and low surface energy.

In short, 4-cyanotrifluorotoluene is rich in chemical properties and has important application value in many fields such as organic synthesis, materials science, medical chemistry, etc. It is a compound that has attracted much attention in organic chemistry research and industrial production.

What are the production methods of 4-bromotrifluorotoluene?

4-Bromotrifluorotoluene is an important intermediate in organic synthesis, and its preparation methods are rich. In ancient books, there are several common methods as follows:

One is to use p-bromotoluene as the starting material, through the steps of side chain halogenation and fluorination. First, p-bromotoluene is placed in a specific reactor, an appropriate amount of initiator is added, bromine is introduced, and the side chain methyl is brominated under light or heating to obtain p-bromobenzyl bromide. Subsequently, this product is reacted with anhydrous hydrogen fluoride in an autoclave under the action of a catalyst, and after a fluorination reaction, 4-bromotrifluorotoluene is finally obtained. In this process, attention must be paid to the precise control of reaction temperature and pressure, as well as the ratio of raw materials to catalysts, in order to prevent side reactions from occurring and affecting the purity and yield of the product.

The second is to use 4-bromobenzoic acid as the starting material, first by esterification to obtain methyl 4-bromobenzoate, and then by reduction with a strong reducing agent to obtain 4-bromobenzyl alcohol, and then brominate the hydroxyl group, and finally by haloform reaction and fluoridation to obtain the target product. First, 4-bromobenzoic acid and methanol are heated and refluxed under the catalysis of concentrated sulfuric acid to complete the esterification reaction and generate methyl 4-bromobenzoate. Then, the ester is treated with a strong reducing agent such as lithium aluminum hydride to obtain 4-bromobenzyl alcohol. Subsequently, phosphorus tribromide and other reagents are used to replace the hydroxyl group with bromine atoms to obtain 4-bromobenzyl bromide. Finally, benzyl bromide is converted into the corresponding carboxyl group by haloform reaction, and then fluorinated to obtain 4-bromotrifluorotoluene. This route has a little more steps, but the reaction conditions in each step are relatively mild, which is conducive to operation and control.

The third is prepared by electrophilic substitution of aromatic hydrocarbons. Trifluorotoluene is used as a substrate, and bromine atoms are directly introduced under suitable catalyst and reaction conditions. Iron or iron salts are often used as catalysts, and bromine is used as a bromination reagent. At appropriate temperatures, trifluorotoluene and bromine undergo electrophilic substitution to generate 4-bromotrifluorotoluene. This method is simple, but the reaction conditions need to be precisely controlled to improve the selectivity of the target product. Because trifluoromethyl is a strong electron-absorbing group, it will affect the electron cloud density distribution on the benzene ring, and then affect the substitution position of bromine atoms.

What are the precautions for the storage and transportation of 4-bromotrifluorotoluene?

4-In the water of the Three Rivers, there are many things that need to be paid attention to. Its nature is strong, and it must be damaged and dry, and it must be connected to a good place. It must not be near the fire or the source of fire, to prevent it from being damaged due to its height and causing damage. And it is appropriate to separate other things, especially avoid mixing with acid and water, in order to avoid chemical reactions, or to cause danger.


It is difficult to separate, and the equipment must be well-packed and dense. Check the equipment first, and it can only be used if there is a risk of damage or leakage. It is hard to be solid, so as to avoid shaking and colliding on the way. The person who sent it must be exposed to the equipment, and be familiar with its nature. On the way, check it, if there is an image, make it urgent.

Also, whether it is stored or not, it is necessary to make it clear. To clarify the name of "4-3 Three Rivers Water", and to attach a warning of danger, so that those who need to know it and be careful. The text is also indispensable. The place where it is stored, the location, the itinerary, and the handover to the destination are all determined, so as to check and trace, to ensure that the whole process is controllable, the risk is minimized, and the safety of people and things is guaranteed.