4 Acetamidobenzenesulfonyl Fluoride
Fluoride

4-Acetamidobenzenesulfonyl Fluoride

Duxiu Chemical

Specifications

HS Code

990422

Name 4-Acetamidobenzenesulfonyl Fluoride
Chemical Formula C8H8FNO3S
Molar Mass 217.22 g/mol
Appearance White to off - white powder
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in many organic solvents like DMSO, DMF
Melting Point 153 - 155 °C
Purity Typically high - purity (e.g., 98%+ in commercial products)
Stability Stable under normal storage conditions, but may react with strong bases or acids
Odor Odorless or very faint odor
Chemical Formula C8H8FNO3S
Molecular Weight 217.22
Appearance White to off - white solid
Melting Point 153 - 156 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in common organic solvents like DMSO, DMF
Purity Typically high - purity (e.g., 98%+)
Stability Stable under normal conditions, but moisture - sensitive
Odor Odorless or very faint odor
Cas Number 33296 - 72 - 3
Storage Conditions Store in a cool, dry place away from moisture

As an accredited 4-Acetamidobenzenesulfonyl Fluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 4 - Acetamidobenzenesulfonyl Fluoride in a sealed, chemical - resistant container.
Storage 4 - Acetamidobenzenesulfonyl Fluoride should be stored in a cool, dry place, away from heat sources and direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and degradation. Store it separately from incompatible substances, such as strong acids and bases. Ideal storage temperature is typically around 2 - 8 °C for long - term stability, especially in a refrigerator if possible.
Shipping 4 - Acetamidobenzenesulfonyl Fluoride is shipped with strict adherence to chemical safety regulations. It's carefully packaged in appropriate containers to prevent leakage, and transported by carriers experienced in handling hazardous chemicals.
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4-Acetamidobenzenesulfonyl Fluoride
General Information
Historical Development
4-Acetaminobenzenesulfonyl fluoride has a history of its development. In the past, all the sages studied the way of chemistry and explored it hard. At first, they didn't know the name of 4-acetaminobenzenesulfonyl fluoride, but everyone studied the wonders of chemistry, and they all thought hard about the properties and methods of making it.
After that, with the passage of time, the research became deeper and deeper, and some wise people discovered this new thing in experiments. Beginning to know its properties, or have unique abilities, they explored it in detail. At that time, I only knew a little or two, but I had already quoted the notes of scholars.
Then, all the sages made unremitting efforts, or changed their methods of making it, or explored their uses. In the long years, the knowledge of 4-acetaminobenzenesulfonyl fluoride has become more and more complete, and it has been well known to the academic community since its inception. Its historical development is the result of the efforts of many scholars, and it is also a clear evidence of the process of chemical research.
Product Overview
4-Acetaminobenzenesulfonyl fluoride is a commonly used product in chemical research. It is a white crystalline powder with high purity. This product is of great significance in biochemical research. It is often used as a protease inhibitor, which can precisely inhibit the activity of specific proteases and block their catalytic reactions. It is very helpful in the field of protein research. And its stability is quite good, and it can be stored for a long time under conventional conditions without changing its properties. It is also necessary to be cautious when using it. Because of its certain toxicity, strict procedures must be followed during operation to ensure safety. With its unique properties, it opens many possibilities for biochemical exploration, and is an indispensable key reagent in the process of scientific research.
Physical & Chemical Properties
4 - Acetamidobenzenesulfonyl Fluoride, its physicalization is very good. Its shape is often solid, the color is more close to white, and the outer surface has a sense of color. The melting factor is the measurement of the quality of the substance. The melting value of this compound has a specific value, and at a certain degree, it will be solid. Its solubility is also special. It can be dissolved in some solutions, but it depends on the solubility in water. This physicalization property affects its performance in the reaction and operation of multiplication, and must be investigated by those who study it.
Technical Specifications & Labeling
Today there is a product called 4 - Acetamidobenzenesulfonyl Fluoride. Those who study this product should take the technical specifications and identification (product parameters) as the main thing.
Its technical specifications are related to the preparation method and purity. The preparation must be based on precise methods, so that no impurities exist and the quality is guaranteed to be pure. The standard of purity is to achieve the highest quality and meet the needs of practicality.
As for the identification (product parameters), the physical properties should be specified, such as color, state, and melting point. It is also necessary to list the chemical characteristics, so that the user can understand its nature and know its danger, so as to prevent misuse from causing disease. In this way, the technical specifications and identification (product parameters) of this product can be obtained, which is beneficial to scientific research and practicality.
Preparation Method
This 4-Acetamidobenzenesulfonyl Fluoride is made in this product, and the first raw material is selected. When p-acetaminobenzenesulfonyl chloride and anhydrous potassium fluoride are used as raw materials, the purity of the two needs to be carefully selected to ensure high quality.
Its production process, in the dry reactor, first set p-acetaminobenzenesulfonyl chloride, followed by low temperature and slow application of anhydrous potassium fluoride, the temperature control is in a moderate range, which is the key. During the mixing, it must be uniform and stable to ensure that the reactants are fully integrated.
In the reaction step, the two are initially cold and polymerized, and gradually rise with the temperature, and then there is a phenomenon of compound. It is necessary to closely observe the reaction situation. When the color in the kettle gradually changes and the smell is slightly different, the reaction is approaching completion.
Catalytic mechanism, appropriate introduction of phase transfer catalyst can promote the reaction to accelerate and increase the yield. After the reaction is completed, after cooling, filtering and purification steps, pure 4-Acetamidobenzenesulfonyl Fluoride can be obtained, and its quality can be used in various scientific research and production.
Chemical Reactions & Modifications
4-Acetaminobenzenesulfonyl fluoride is also a chemical substance. Its chemical reaction and modification are related to many wonders.
When this substance reacts, functional groups interact with each other, or nucleophilic substitution, or electron cloud rearrangement. For example, sulfonyl fluoride has strong activity, which is easy to merge with nucleophilic reagents, generate new chemical bonds, and cause structural changes.
And the modification method is designed to adjust its performance. Or change its solubility to suit different media; or increase its stability to prevent it from easily decomposing. Chemists study its reaction mechanism and explore the modification method, hoping to expand its use in the fields of medicine and materials, and contribute to the progress of chemistry.
Synonyms & Product Names
4 - Acetamidobenzenesulfonyl Fluoride, which is of great importance in the field of chemical research. There are many other names, such as acetamidobenzene - 4 - sulfonyl fluoride, and the trade name is commonly known as Pefabloc SC. Among the various names, although the names are different, they all refer to the same thing. This substance has unique properties and plays a key role in specific reactions and research applications. Many scholars have studied its characteristics and applications. Different names are easy to use in different literature and communication scenarios to meet diverse research and practice needs. However, its roots are all centered on 4 - Acetamidobenzenesulfonyl Fluoride, a core substance. Whether it is called its alias or trade name, it helps the scientific research process and promotes the development of chemical research.
Safety & Operational Standards
4-Acetaminobenzenesulfonyl fluoride, the genus of chemical products. Its safety and operating standards are of great importance and should not be careless.
Anyone who handles this thing must read its instructions carefully and be familiar with its properties. This product is poisonous to a certain extent, and it can be harmful to the body by touching it, smelling it or eating it. Therefore, when operating, protective gear must be worn, such as gloves, masks, goggles, etc., to prevent it from connecting with the body. And the operation must be well ventilated, so that the air is smooth and the poison is dissipated.
There are also regulations for storing this thing. It should be placed in a cool, dry and ventilated place, protected from fire and heat, and away from flammable and explosive things. The reservoir must be sealed to prevent it from leaking out.
If you accidentally touch it, flush it with a lot of water as soon as possible, and it is advisable to flush it for a long time, and then seek medical attention. If it enters the eye, buffer it with water faster, and seek medical attention urgently.
During operation, do not eat, drink, or smoke to prevent it from entering the body. After operation, clean your hands and face, and remove protective equipment.
These are the safety and operation regulations of 4-acetaminobenzenesulfonyl fluoride. If you follow them, it will be safe, and if you don't, it will be dangerous. Operators should be careful.
Application Area
4-Acetaminobenzenesulfonyl fluoride, its application field, is related to many fields of biochemical pharmacology. In protein research, it can produce serine protease activity, block enzymatic reactions, preserve protein activity and structure, so that the research is accurate. In medical research, to explore the pathogenesis of diseases, research new therapies and drugs, this product is also very useful. It can observe the role of enzymes in disease physiology and assist in the development of new drugs. Biochemical experiments are commonly used reagents, which can control specific enzyme activities and facilitate the analysis of biochemical processes. In biopharmaceuticals, prevent protein degradation and ensure product quality and activity. In short, 4-acetaminobenzenesulfonyl fluoride is widely used in biochemical and pharmaceutical research, which has greatly contributed to the progress of scientific research.
Research & Development
In recent times, the art of chemistry has become more and more refined, and various compounds have emerged in an endless stream. Today there are 4-Acetamidobenzenesulfonyl Fluoride, which our researchers have carefully studied.
At the beginning, it was very difficult to explore its structure and properties. Everyone worked in the laboratory day and night, and measured it with various instruments to understand the wonderful structure of its molecules and know the strangeness of its characteristics.
Then, think about its application and expansion. After repeated tests, it can be used in the field of biochemistry to make special drugs, block the activity of enzymes, and benefit patients. And explore its materials, or it can improve the texture and increase its performance.
We are determined to make unremitting efforts to develop the functions of 4-Acetamidobenzenesulfonyl Fluoride, promote the progress of scientific research, promote the development of society, and leave far-reaching achievements for future generations.
Toxicity Research
Taste the nature of things, it is related to the safety of use. Today's research 4 - Acetamidobenzenesulfonyl Fluoride The toxicity of this substance is really important.
4 - Acetamidobenzenesulfonyl Fluoride, or used for various experiments. However, when its toxicity is unknown, it should not be ignored. After various tests, observe its impact on living beings. Observe its entry into the body, or disturb the normal order of physiology, and damage the ability of the viscera. Although no aggressive form is seen, it is slightly harmful to the potential, and it must be prevented.
The study of toxicity requires caution. Examine its changes carefully, investigate its causes carefully, and understand the depth of its harm and the distance of its spread. In this way, we can know when this thing is in use, how to avoid harm and profit, and ensure the well-being of the people, so that it can be used to its fullest potential without harm to the world.
Future Prospects
In today's world, science and technology are advancing day by day, and new things are emerging frequently. In the field of chemistry, 4-Acetamidobenzenesulfonyl Fluoride has emerged. Its unique nature, in the process of scientific research, has infinite potential.
Although the application of this thing at present, or it is still in its infancy, the future prospects are really fascinating. It can be predicted that in the realm of medical research and development, it can eliminate diseases and diseases, and open up new paths; in the field of biochemical exploration, it can help solve the mysteries of life, and understand the unknown.
In the future, with time and careful study, it will be able to make its effectiveness fully apparent, and add bricks and tiles to human well-being, and develop endless brilliant prospects. This is something that can be hoped for in the future.
Historical Development
The historical development of 4-acetaminobenzenesulfonyl fluoride is related to the process of chemical research. At the beginning, when researchers were exploring various chemicals, they gradually paid attention to this. The method of its synthesis has undergone several improvements. In the past, the experimental conditions were limited, and the progress was rather slow. However, various scholars worked tirelessly to understand its characteristics. In the field of biochemical research, its use is becoming increasingly apparent. From the initial ignorance and trial, to the later generation's clarification of its effectiveness in inhibiting specific enzymes, it has been advancing step by step. Today, 4-acetaminobenzenesulfonyl fluoride plays an important role in many places such as scientific research and pharmaceutical preparation. This is the result of the efforts of researchers of all generations to achieve this historical development.
Product Overview
4-Acetaminobenzenesulfonyl fluoride, an organic compound. Its shape or powder, white and pure. In the field of biochemistry, it has a wide range of uses. Often used as a protease inhibitor, it can block the activity of proteases and help a lot in protein research.
This substance is stable in nature, and will change in case of water or strong acid and alkali. When using, when in accordance with the specifications, ensure its effectiveness and safety. When preparing, it requires delicate methods, control conditions, and seek its purity.
4-Acetaminobenzenesulfonyl fluoride, in biochemical research, is a useful material, promoting research, and has contributed greatly.
Physical & Chemical Properties
4-Acetamidobenzenesulfonyl Fluoride, that is, 4-acetamidobenzenesulfonyl fluoride, is unique in physical properties. Its shape may be crystalline, white and pure in color. The melting point has a certain number, which is related to the change of its state. The solubility is different from that of various solvents, and it is slightly soluble in water or slightly soluble in organic solvents or better in solubility. Its chemical activity is active, and it can interact with various reagents. Both the amide group and the sulfonyl fluoride group are the corresponding check point, or participate in various reactions such as nucleophilic substitution. Because of its unique physical and chemical properties, it is quite useful in biochemical research and other fields. It can prepare inhibitors to block the activity of specific enzymes, and help scientific research and explore the mystery of life.
Technical Specifications & Labeling
Today there is a product named 4 - Acetamidobenzenesulfonyl Fluoride. Its process specifications and identification (commodity parameters) are the key. In terms of its process specifications, when there is a precise production method, from the selection of raw materials to various reaction conditions, such as temperature, duration, ratio, etc., it needs to be strictly controlled to obtain high-quality products. In terms of identification, it is necessary to specify its composition, characteristics and uses, so that users can see at a glance. In terms of commodity parameters, Quality Standards, purity geometry, packaging specifications, etc., can not be missed. In this way, the quality and application of this product can be guaranteed, and the exact basis for all users can be provided to achieve its expected effect.
Preparation Method
The preparation of 4-acetaminobenzenesulfonyl fluoride is related to the raw materials and production process, reaction steps and catalytic mechanism. To make this product, first take an appropriate amount of acetaminophen as the base material and skillfully mix it with chlorosulfonic acid. In the claustrophobic reactor, control the appropriate temperature and humidity to make it respond quietly. Among them, the control of temperature is extremely important. If it is too high, the product will be easily divergent, and if it is too low, the reaction will be slow.
At the beginning of the reaction, the raw materials slowly blend, and the catalytic agent is added in time to promote the agility of its molecules and accelerate the reaction pace. As the reaction evolves, closely observe its signs and fine-tune the conditions according to changes. When the reaction is approaching the end, apply a delicate separation technique to remove its impurities and leave the pure product.
In this way, after careful raw material selection, precise process control, and rigorous reaction promotion, 4-acetaminobenzenesulfonyl fluoride has been exquisitely prepared, resulting in this excellent product.
Chemical Reactions & Modifications
4-Acetaminobenzenesulfonyl fluoride is an important chemical substance related to chemical reaction and modification. Its reaction can also interact with various reagents under suitable conditions. In case of nucleophilic reagents or nucleophilic substitution reactions, the activity of its sulfonyl fluoride group is also the reason.
As for modification, in order to optimize its performance, there are often things to do. Or by means of chemical modification, it can increase the group on its molecular structure. In this way, its solubility or stability can be changed. After modification, 4-acetaminobenzenesulfonyl fluoride can be better used in biochemical research and other fields, and it can play a more significant role in protein analysis and other aspects, and help the progress of chemistry and related disciplines.
Synonyms & Product Names
4-Acetaminobenzenesulfonyl fluoride, which is widely used in biochemical research. There are many other names, such as benzenesulfonyl fluoride. When the merchant names it, there are also specific trade names.
The academic name of Guanfugu, in the name of the thing, is often called differently by region and school. Today's 4-acetaminobenzenesulfonyl fluoride, although the chemical name is clear, in the actual research and trade environment, aliases and trade names are parallel.
Scholars should understand its many terms, so as not to be confused by the different names when they are researching and seeking. If a doctor uses drugs, he must know the names of various drugs in detail before he can use them correctly, and the same is true for biochemical research. He is familiar with the synonyms and trade names of 4-acetaminobenzenesulfonyl fluoride. Experiments and discussions are all important.
Safety & Operational Standards
4-Acetaminobenzenesulfonyl fluoride is also a chemical product. It is related to safety and operating standards, and is of paramount importance and cannot be ignored.
When using this material, safety is the first priority. When hiding it, it should be placed in a cool, dry and well-ventilated place to avoid open flames and hot topics. Because of the risk of explosion, it should never be stored near a fire. When taking it, it is necessary to wear protective equipment, such as gloves, goggles, etc., to avoid contact with the skin and eyes. If you accidentally touch it, rinse it with a lot of water quickly. If you are still unwell, seek medical attention urgently.
Operating norms should not be ignored. Perform relevant operations in the fume hood to allow harmful gases to dissipate in time and ensure environmental safety. Read the instructions carefully before use to explain its properties and operation methods. Weigh accurately and mix the solution according to the procedure. Store the residue properly after use, do not discard it at will, and prevent the environment from fouling.
Furthermore, it is necessary to record the experiment in detail, and remember when to use it, the dosage geometry, and the operation conditions. In this way, if there is a problem, it can be traced back, and follow-up research is also beneficial. In short, the safety and operation specifications of 4-acetaminobenzenesulfonyl fluoride are related to the safety of the experimenter and the success or failure of the research, and should not be taken lightly. Strict rules must be followed to ensure that everything goes smoothly.
Application Area
4-Acetaminobenzenesulfonyl fluoride is widely used in the field of biochemistry. It is often used as a protease inhibitor and is crucial in protein research. It can specifically bind to the checkpoint of protease activity, block its catalytic effect, and restrict the proteolysis process. In cell biology experiments, this agent is commonly used to maintain the stability of intracellular proteins and prevent degradation. And in the exploration of disease mechanisms, the road of drug development is also indispensable. Because it can precisely regulate protease activity, research assistants can analyze disease-related protein pathways, find key targets for new drug creation, and hope to treat many diseases, open up new paths, and benefit patients.
Research & Development
Modern chemistry has advanced, and material research has deepened. 4 - Acetamidobenzenesulfonyl Fluoride This material has gradually become more and more important in the academic world. Study its properties, explore its quality, and conduct various experiments. Repeated investigation.
At the beginning, only a little bit of its characteristics were known, and scholars tried their best to understand its details. Or in various environments, observe its changes; or in harmony with other things, observe its reactions. After several years, there is something to gain.
The field of its application has also gradually expanded. The road of medicine may help the observation of diseases; the world of biochemistry can add wings to research. However, the road to research is still bumpy. The removal of impurities and the rise of purity are all difficult problems.
However, the heart of a scholar is persevering. Despite the difficulties, I still strive to move forward, hoping for the future, to be able to fully understand the mystery of this thing, expand its use, and add bricks to the well-being of the academic community and the world, and promote its rapid development.
Toxicity Research
Today there is a thing named 4 - Acetamidobenzenesulfonyl Fluoride, which is quite important in the study of toxicity. We study it, observe its nature, and investigate its harm. The toxicity of this thing is related to the health of living beings, and we must not fail to examine it carefully.
To study the toxicity of this thing, we need to follow the scientific method to observe its response to various things. Observe the change of its entry into the body, and the effect of it on the viscera and meridians. Or cause cell damage, or disrupt the order of physiology.
Although this substance has good uses, it cannot be prevented from toxicity. We must understand the depth of its harm, and determine the protective policy, so that those who use it are safe and peaceful. Expected to obtain a detailed fruit, for those who use this thing in the future, it refers to a safe way to avoid the risk of poisoning.
Future Prospects
Guanfu 4 - Acetamidobenzenesulfonyl Fluoride is the key to chemical research. At present, although its properties and uses are already known, there is still a broad range in the future.
It can cover the way of biochemical research, or it can open up new paths and help explore the mystery of life. The field of medicine may be a sharp tool for curing diseases and relieving the suffering of patients. In the world of industry, it may also lead to the innovation of technology to increase the effect of production.
Our researchers should have lofty ambitions and explore deeply. With time, 4 - Acetamidobenzenesulfonyl Fluoride will be able to shine brightly in the future, for the well-being of mankind and the progress of science and technology, to build unparalleled achievements, to achieve unfinished business, and to develop infinite possibilities.
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Frequently Asked Questions

As a leading 4-Acetamidobenzenesulfonyl Fluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Acetamidobenzenesulfonyl Fluoride?
4-Acetaminobenzenesulfonyl fluoride, its use is quite important. This substance is often used as a protease inhibitor in the field of biochemical research. It plays a key role in many physiological processes in living organisms, such as apoptosis, immune response and blood coagulation. 4-Acetaminobenzenesulfonyl fluoride can combine with the activity check point of protease, thereby inhibiting its activity and precisely regulating such physiological processes.
4-Acetaminobenzenesulfonyl fluoride also plays a key role in the development of medicine. Pharmaceutical developers can use its properties to inhibit specific proteases to explore therapies for related diseases. For example, in some inflammatory diseases and tumor diseases, the abnormal activity of specific proteases is a key pathological factor. This substance inhibits the protease and may provide an effective strategy for disease treatment.
Furthermore, in the field of proteomics research, 4-acetaminobenzenesulfonyl fluoride is also indispensable. Proteomics aims to comprehensively understand the composition and function of proteins in organisms. This substance can help researchers stabilize protein samples by inhibiting protease activity, ensure more accurate and reliable analysis of proteins, and then promote the progress of proteomics research.
Overall, 4-acetaminobenzenesulfonyl fluoride has important uses in the fields of biochemistry, medicine and proteomics, providing key assistance for related research and applications.
4-Acetamidobenzenesulfonyl Fluoride's mechanism of action
4-Acetaminobenzenesulfonyl fluoride, often abbreviated as Pefabloc SC, is an extremely important reagent in biochemical research. Its mechanism of action is delicate and complex, allowing me to explain in detail.
This reagent is mainly effective against serine protease. Serine proteases play a key role in many physiological and pathological processes, such as coagulation, fibrinolysis, complement activation, and inflammation. 4-Acetaminobenzenesulfonyl fluoride has a unique structure and contains a highly reactive sulfonyl fluoride group. When this reagent meets serine protease, the sulfonyl fluoride group binds specifically to the hydroxyl group of the serine residue at the center of serine protease activity.
This covalent binding is of great significance. It is like shackling the active center of the serine protease, which greatly changes the structure and charge distribution of the active center of the protease. The change of the active center structure makes it difficult for the substrate to bind normally to the protease. It is like the keyhole is blocked by a foreign body, and the key cannot be inserted, and the specific recognition and binding process between the substrate and the protease are seriously hindered. The change of charge distribution cannot be ignored. It destroys the microenvironment required for the catalytic reaction of the protease, making the protease unable to provide suitable catalytic conditions for the substrate, so it cannot efficiently catalyze the reaction of the substrate. As a result, the activity of the serine protease is significantly inhibited, and its function in physiological or pathological processes cannot be performed normally.
It is based on this mechanism of action that 4-acetaminobenzenesulfonyl fluoride is widely used in biochemical research, enabling researchers to deeply explore the various life activities involved in serine proteases, opening up many new paths for research in related fields.
What to pay attention to when using 4-Acetamidobenzenesulfonyl Fluoride
4-Acetaminobenzenesulfonyl fluoride is a highly toxic chemical reagent. When using it, many matters need to be paid attention to.
First safety protection. Suitable protective equipment must be worn, such as laboratory clothes, gloves, protective glasses and gas masks. This reagent is highly toxic and can be absorbed through the skin and irritate the respiratory tract. If the protection is not careful, it will endanger personal safety. Gloves are selected to be chemically resistant. The mask must have an efficient filtration function to block its volatile gases.
Times and operating environment. It is suitable for operation in a well-ventilated fume hood. The fume hood can drain the volatile gas in time, reduce its concentration in the air, and reduce the risk of inhalation by the operator. Before operation, check whether the fume hood is running normally.
Furthermore, take it accurately. Because it is highly toxic, the dosage must be accurate. Use suitable instruments, such as pipettes and balances, to measure accurately according to the experimental needs. Immediately after taking it, seal the container to prevent it from being exposed to air and volatilizing or deliquescent causing changes in properties.
In addition, avoid improper mixing. Do not mix with incompatible chemicals at will to prevent violent reactions, generate more toxic substances or cause serious accidents such as explosions. Before use, read the chemical safety technical manual carefully to explain its chemical properties and contraindications.
Finally, dispose of waste properly. Residual reagents in experiments and items that have been in contact are hazardous waste. It must be collected in accordance with relevant regulations and laboratory regulations, and handed over to professional institutions for processing. It must never be discarded at will to avoid polluting the environment and endangering others.
The use of 4-acetaminobenzenesulfonyl fluoride requires caution in all aspects and strict operation in accordance with regulations to ensure experimental safety, personnel health and the environment.
4-Acetamidobenzenesulfonyl Fluoride is safe
4-Acetaminobenzenesulfonyl fluoride, the safety of this substance is related to many things. It is a highly active reagent, often used to inhibit protease, and has many applications in the field of biochemical research.
In terms of toxicity, it may be potentially harmful. If inadvertently contacted through the skin, it can seep into the skin, causing local irritation such as redness, itching, or even burns. If inhaled, its dust or volatile gaseous substances can damage the respiratory tract, causing coughing, asthma, dyspnea, etc. Long-term or high-concentration exposure, or irreversible damage to the lungs and other organs. If taken by mistake, the irritation to the digestive tract can be severe, causing nausea, vomiting, abdominal pain, and life-threatening in severe cases.
From the perspective of stability, it is relatively stable under specific conditions. In case of high temperature, open flame, or mixed with strong oxidants, strong alkalis and other substances, it can cause chemical reactions, or cause the risk of combustion and explosion.
In terms of storage, it is necessary to place in a cool, dry and well-ventilated place, away from fire and heat sources, and separate from contraindicated substances. The storage place should be equipped with corresponding emergency treatment equipment and suitable containment materials.
During operation, strict protection must be taken. Experimenters should wear protective clothing, protective gloves and goggles, and operate in the fume hood to prevent contact and inhalation. After operation, properly dispose of the remaining reagents and waste, and must not be discarded at will to avoid polluting the environment.
In summary, the safety of 4-acetaminobenzenesulfonyl fluoride requires all-round consideration, careful operation and proper storage to reduce latent risks, ensure personnel safety and environmental harmlessness.
How 4-Acetamidobenzenesulfonyl Fluoride is Preserved
4-Acetaminobenzenesulfonyl fluoride is a highly sensitive and strong serine protease inhibitor. This substance has high activity and can easily react with surrounding chemicals, so its preservation method is very important.
To properly store this agent, it should first be placed in a low temperature environment. It should be stored in a low temperature refrigerator at -20 ° C or even -80 ° C. Low temperature can reduce its molecular active level, reduce its chemical reaction rate, and keep it stable for a long time. If the ambient temperature is too high, its structure is easily damaged and its activity is sharply reduced.
Second, make sure that the storage place is dry and free of moisture. Moisture can cause it to hydrolyze and then deactivate. Therefore, when stored in a sealed container, a desiccant can be added to the side, such as a silica gel package, to absorb the water vapor that may penetrate and keep it dry.
Furthermore, avoid contact with strong reactive substances such as oxidizing agents and reducing agents. These substances can cause their chemical structure to change and impair their ability to inhibit proteases. In the laboratory, it should be kept alone and away from other chemicals.
Also, avoid repeated freezing and thawing. After each freezing and thawing cycle, its activity may be lost. If necessary, it should be stored separately as needed, and an appropriate amount should be taken each time. The rest should still be kept at low temperature to avoid reducing its activity due to repeated freezing and thawing. In this way, the activity and stability of 4-acetaminobenzenesulfonyl fluoride can be guaranteed, so that it can be used for scientific research and other purposes.