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What is the main use of 4- (2-Hydroxyethylamino) -3-Nitrobenzotrifluoride?
4- (2-hydroxyethylamino) -3-nitrotrifluorotoluene is widely used. In the field of medicinal chemistry, it is a key organic synthesis intermediate. With its unique chemical structure, it can participate in a variety of chemical reactions, help build complex drug molecular structures, and make great contributions to the development of new drugs.
In the field of materials science, it can be used as a synthetic raw material for functional materials. After specific processing, it can give materials such as special optical, electrical or thermal properties, and plays an important role in the preparation of advanced materials.
In agricultural chemistry, it may be used to create new pesticides. Due to its structural characteristics, or its unique inhibitory or killing effect on certain pests and pathogens, it provides a new way for agricultural pest control.
And because of its fluorine, nitro and other special groups, in organic synthetic chemistry, it is often used to introduce specific functional groups, expand the structural types and properties of organic compounds, and promote the continuous development of organic synthetic chemistry.
What are the synthesis methods of 4- (2-Hydroxyethylamino) -3-Nitrobenzotrifluoride
The synthesis method of 4 - (2 -hydroxyethylamino) - 3 -nitrotrifluorotoluene is as follows.
To obtain this compound, the common way is to use the starting material containing a specific functional group, through several steps of chemical reaction. First take the aromatic hydrocarbon with a suitable substituent and use the trifluoromethylation reagent to introduce the trifluoromethyl. This step requires strict control of the reaction conditions, such as temperature, reaction time and reagent dosage. Due to the harsh conditions of the trifluoromethylation reaction, the product is not pure if there is a slight difference.
Then, nitro is introduced at a suitable position of the aromatic hydrocarbon. The introduction of nitro groups is mostly a mixed acid (a mixture of concentrated sulfuric acid and concentrated nitric acid) as a nitrifying reagent. This reaction also needs to be finely regulated to prevent excessive nitrification, resulting in complex and difficult product separation.
Furthermore, the hydroxyl-containing ethylamine reagents react with aromatic hydrocarbons that already have trifluoromethyl and nitro groups to form 4- (2-hydroxyethylamino) -3-nitrotrifluorotoluene. In this step, a suitable catalyst may be required to promote the nucleophilic substitution reaction of amino groups and aromatics at a suitable check point. It is also necessary to pay attention to the pH and temperature of the reaction system to make the reaction proceed smoothly and improve the yield of the product.
After each step, separation and purification techniques, such as column chromatography and recrystallization, are required to obtain pure 4- (2-hydroxyethylamino) -3-nitrotrifluorotoluene. These synthesis methods need to be flexibly adjusted according to the actual situation to achieve the best synthesis effect.
What are the physical properties of 4- (2-Hydroxyethylamino) -3-Nitrobenzotrifluoride
4- (2-hydroxyethylamino) -3-nitrotrifluorotoluene is one of the organic compounds. Its physical properties are of great value for investigation.
First of all, its appearance is often in a colorlike state, or a light yellow to brown liquid, or a solid, depending on the temperature and pressure of the environment. The formation of its color is related to the chemical bonds and electron cloud distribution within the molecule, resulting in specific absorption and reflection of light.
Melting point and boiling point. Melting point, the temperature at which a substance changes from a solid state to a liquid state. The melting point of this compound depends on the interaction forces between molecules, such as van der Waals force, hydrogen bond, etc. The structure and polarity of molecules are greatly affected by this force. The boiling point is related to the temperature of liquid to gaseous state, and its value is determined by the intermolecular force and the relative molecular weight. The larger the relative molecular weight, the stronger the intermolecular force, and the higher the boiling point.
Furthermore, solubility is also an important property. In organic solvents, such as ethanol, acetone, etc., its solubility may be good. Because the compound has a certain polarity, it is similar to the polarity of organic solvents, and can be dissolved according to the principle of "similar miscibility". The solubility in water may vary due to the different forces between water molecules and compounds. If the molecule contains groups that can form hydrogen bonds with water, such as hydroxyl groups, its solubility in water may increase.
In addition, density is also one of the physical properties. Its density reflects the mass of the substance per unit volume and is related to the stacking mode and relative molecular weight of the molecules.
In summary, the physical properties of 4- (2-hydroxyethylamino) -3-nitrotrifluorotoluene are influenced by factors such as molecular structure, relative molecular weight and intermolecular forces, and are also closely related to these properties in the fields of chemical engineering and materials.
What are the chemical properties of 4- (2-Hydroxyethylamino) -3-Nitrobenzotrifluoride
4- (2-hydroxyethylamino) -3-nitrotrifluorotoluene, this is an organic compound. Its chemical properties are unique and valuable for investigation.
First of all, its solubility is mentioned, and it has a certain solubility in common organic solvents, such as ethanol and acetone. This is because there are polar groups in the molecule, such as hydroxyl and amino groups, which can interact with organic solvent molecules to form hydrogen bonds, thereby enhancing dissolution.
Besides, its stability is different because the molecule contains nitro and trifluoromethyl groups. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring and makes the benzene ring more prone to nucleophilic substitution. Trifluoromethyl is a strong electron-absorbing group, which can enhance molecular stability and affect molecular polarity.
When it comes to reactivity, amino and hydroxyl groups can participate in a variety of reactions. Amino groups can undergo acylation and alkylation reactions, and hydroxyl groups can undergo esterification and etherification reactions. In addition, nitro groups can be reduced to amino groups, which are important reactions in organic synthesis and can be used to prepare amino-containing derivatives.
In terms of acidity and alkalinity, amino groups can react with acids to form salts because of their certain alkalinity. Hydroxyl groups can also show acidity under specific conditions and participate in acid-base related reactions. The chemical properties of 4- (2-hydroxyethylamino) -3-nitrotrifluorotoluene are rich and diverse, and it has broad application prospects in organic synthesis, medicinal chemistry and other fields.
What is the price range of 4- (2-Hydroxyethylamino) -3-Nitrobenzotrifluoride in the market?
4 - (2 -hydroxyethylamino) -3 -nitrotrifluorotoluene. It is difficult to determine the price range of this product in the market. The price of this product often varies due to many reasons, such as the price of raw materials, supply and demand conditions, and differences in production methods.
Looking at the market of chemical products in the past, the fluctuation of raw material prices has a great impact on the price of finished products. If the price of raw materials for this product rises, the price will also rise; on the contrary, if the price of raw materials decreases, the price may decline.
The supply and demand situation is also the key. If there is a strong demand for this product in the market, but the supply is limited, the price must be high; if the demand is weak and the supply is abundant, the price may decline.
Furthermore, the production method is different, the cost is different, and the price is also different. The refined method may reduce the cost and improve the efficiency, so that the price is competitive; the cumbersome method, the cost is high, and the price is also high.
However, the market situation is unpredictable today. To know the exact price, you should consult the chemical material supplier, the market research agency, or the chemical trading platform to get a more accurate price range.