4 2 Aminoethyl Benzenesulfonyl Fluoride Hydrochloride
Fluoride

4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride

Duxiu Chemical

Specifications

HS Code

184143

Name 4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride
Chemical Formula C8H11ClFNO2S
Molar Mass 239.7 g/mol
Appearance Typically a white to off - white solid
Solubility Soluble in polar solvents like water and some organic solvents
Purity Often sold with high purity, e.g., 98%+
Storage Condition Should be stored at -20°C, protected from moisture
Cas Number 77730-37-3
Melting Point May have a melting point in a certain range (data may vary)
Function An inhibitor, often used in biochemical research
Name 4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride
Chemical Formula C8H11ClFNO2S
Molecular Weight 239.7 g/mol
Appearance Typically a solid
Solubility Soluble in some polar solvents
Cas Number 329-98-6
Purity Varies by supplier, often high purity available
Storage Condition Stored at -20°C or as specified
Function A protease inhibitor
Melting Point Specific melting point data depends on purity
Safety Hazard May have irritant properties
Packing & Storage
Packing 100g of 4-(2 - Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride in sealed vial.
Storage 4-(2 - Aminoethyl)benzenesulfonyl fluoride hydrochloride should be stored in a cool, dry place away from heat and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contamination. Store it separately from incompatible substances. Ideal storage temperatures are typically around 2 - 8 °C if refrigerated storage is recommended by the supplier.
Shipping 4-(2 - Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride is shipped with strict adherence to chemical transportation regulations. It's packaged securely to prevent leakage, in containers suitable for its hazardous nature, ensuring safe transit.
Free Quote

For samples, pricing, or more information, please call us at +8615365036030 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365036030

Email: info@alchemist-chem.com

4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride
General Information
Historical Development
In a long time, there was a substance called 4-2-aminoethylbenzenesulfonyl fluorohydrochloride. Its initial appearance was only discovered by a few scholars in the subtle research. At that time, the scientific path was still narrow, and its understanding was only like seeing flowers in the fog, which was hazy and difficult to distinguish.
However, as the years passed, as various studies deepened, this substance gradually emerged. Scholars studied it carefully, unremitting exploration, and repeated deliberation in their laboratories. From the initial ignorance, to the gradual understanding of its nature, I knew the wonderful changes between various reactions.
Every step of progress has gathered countless efforts. From simple instruments to precise instruments, its development path is full of thorns, but it is also slowly paved due to the persistence of researchers. The historical evolution of this material is like a pearl. In the long river of science, it gradually shines from dimness, waiting for more brilliance to bloom.
Product Overview
4-2-Aminoethylbenzenesulfonyl fluorohydrochloride is an important substance in chemical research. It has unique characteristics, appearance or white crystalline powder, stable properties, and can also react with specific reagents. This compound has a wide range of uses in biochemical research. It can be used as a protease inhibitor to precisely inhibit the activity of specific proteases, providing assistance for the study of the function and mechanism of proteases. The synthesis method requires rigorous steps, suitable raw materials, and multiple reaction processes. When storing, also pay attention to the conditions. It should be placed in a cool and dry place to avoid moisture and heat to prevent its deterioration, to ensure its effectiveness in scientific research applications, and to contribute to the exploration of chemical and biological sciences.
Physical & Chemical Properties
4-2-Aminoethylbenzene sulfonyl fluoride hydrochloride is an important substance for chemical research. Its physical properties are mostly white crystalline at room temperature, and those with pure quality are crystal clear and delicate, and it looks like jade chips. Its chemical properties are active, and the sulfonyl fluoryl group has strong reactivity. It is easy to interact with a variety of nucleophiles, and has a wide range of uses in the field of organic synthesis. The stability of this compound is also concerned. It needs to be properly stored in a dry and cool place to avoid contact with strong oxidants and strong bases, otherwise it will easily decompose and damage its properties. Therefore, it is of great significance to study the physical and chemical properties of this substance for the development of chemical synthesis and related fields.
Technical Specifications & Labeling
4 2 -Aminoethylbenzenesulfonyl fluorohydrochloride is an important substance for chemical research. Its technical specifications and identification (commodity parameters) are crucial. Looking at this substance, its technical specifications need to be precisely determined, and the proportion of ingredients and the geometry of purity need to be detailed. In terms of identification, the name must be exact, the writing cannot be wrong, and the relevant symbols and codes should also follow the specifications.
During research and manufacturing, according to precise technical specifications, the quality of the product can be guaranteed. And clear identification allows researchers to quickly identify its properties and use it correctly. If the purity is not up to the specification, or the identification is vague, the experimental deviation may be caused, and the result will be wrong. Therefore, strict adherence to the technical specifications and labels of 4 2-aminoethylbenzenesulfonyl fluorohydrochloride is the foundation of scientific research and the key to excellent products.
Preparation Method
The preparation method of 4-2-aminoethylbenzenesulfonyl fluorohydrochloride is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are well selected and formed through multiple careful reaction steps. The benzenesulfonyl chloride and amino ethanol are initially used as the starting point. In the reaction environment of suitable temperature and pH, with the help of specific catalysts, the two are cleverly combined. The reaction process is carefully controlled, and the rate, temperature and pH are adjusted in a timely manner to achieve the best reaction state. When the reaction is complete, through separation, purification and other processes, impurities are removed and essence is retained, and high-purity 4-2-aminoethylbenzenesulfonyl fluorohydrochloride is finally obtained. This preparation method, rigorous process, and complementary raw materials and catalytic mechanisms are essential for the production of high-quality products.
Chemical Reactions & Modifications
4-2-Aminoethylbenzenesulfonyl fluoride hydrochloride is a key chemical reaction and modification. Looking at the reaction, under suitable conditions, the groups such as aminoethyl and benzenesulfonyl fluoride in its molecular structure can interact with many reactants, undergo substitution, addition and other reactions, and then derive new compounds. When it comes to modification, its performance can be optimized by adjusting the reaction conditions, such as temperature, pH, and the ratio of reactants. Or enhance its stability, or improve its solubility, in the fields of medicine, chemical industry, etc. Through fine manipulation of chemical reactions, this compound can exhibit better properties to meet diverse needs.
Synonyms & Product Names
4-2-Aminoethylbenzenesulfonyl fluorohydrochloride is especially important in the field of my chemical research. It shares various names and is also known in the industry. Or benzenesulfonyl fluoride is a genus with different names, but it is actually the same thing.
In ancient books, this thing may have another name, and it all refers to the same thing. If looking for its commercial name, there are also other names, but it refers to this 4-2-aminoethylbenzenesulfonyl fluorohydrochloride. Although its name is different, its nature is actually one, and it is useful in chemical research and pharmaceuticals. Either as a reaction agent or as a synthetic material, under different names, we can perform the same function, helping our generation to continuously explore, clarify its nature, and make good use of it. This will contribute to the progress of academia and industry, and jointly promote the prosperity of chemistry.
Safety & Operational Standards
4-2-Aminoethylbenzenesulfonyl fluorohydrochloride, this chemical substance is essential for safety and operating standards. Its guidelines must be detailed to ensure the smooth operation of the experiment and the safety of personnel.
When taking it, it is necessary to abide by the rules of cleanliness. Hands should be clean and dry, and the utensils used should also be clean and unstained. First scoop an appropriate amount of the product with a clean spoon. The action should be slow and do not spill. If it spills accidentally, clean it immediately to prevent contamination of the surrounding area.
When storing, it should be placed in a cool, dry and well-ventilated place. Keep away from heat sources and open flames to avoid heat decomposition or danger. The place of storage should be marked prominently, indicating the characteristics and hazards of this substance.
In the experimental operation room, ventilation equipment must be working properly. This substance may be irritating, and if operated in a closed space, its volatile gas may easily cause discomfort to personnel. Operators need professional protective equipment, such as laboratory clothes, gloves, and protective goggles, to prevent it from coming into contact with skin and eyes.
In case of accidental contact with skin, rinse with plenty of water immediately, and then seek medical attention.
In short, the safety and operating practices of 4-2-aminoethylbenzenesulfonyl fluorohydrochloride are the foundation for experimental safety. Only by strictly following these regulations can we effectively avoid risks and ensure the smooth operation of the experiment and the well-being of personnel.
Application Area
4 2-Aminoethylbenzenesulfonyl fluorohydrochloride is widely used in the field of biochemical research. In the study of proteolytic enzymes, it can specifically inhibit serine protease. Serine residues in the active center of capping serine protease can easily bind to this compound, inactivating the enzyme, helping researchers to understand the mechanism of action of such enzymes.
In cell biology experiments, it can be used to prevent the proteolytic cascade reaction in cells and maintain protein homeostasis in cells. In pharmaceutical research and development, it can be used as a tool compound to explore the function of disease-related proteases, and help to discover and confirm potential drug targets. It is also used in the protein purification process to prevent the target protein from being degraded by proteases and ensure the integrity and activity of the extracted protein.
Research & Development
Today there is a substance, named 4-2-aminoethylbenzenesulfonyl fluorohydrochloride. As a chemical researcher, I look at this substance and think about its research and development path. This substance has unique properties and may be of great use in the field of biochemical research.
We should carefully investigate its structure and explore the reaction mechanism to clarify its properties. After repeated experiments, it is hoped that the synthesis method can be optimized, and the yield and purity can be improved. If this substance is properly developed, it may help medical research, such as emerging in enzyme inhibition research, and provide assistance for overcoming difficult diseases.
Our generation should study diligently and explore unremittingly to maximize the value of this substance, contribute to the development of the chemical field, promote the progress of science and technology, and benefit all living beings.
Toxicity Research
To study the toxicity of 4-2-aminoethylbenzenesulfonyl fluorohydrochloride. This chemical has been used occasionally in biochemical experiments, but its toxicity has not been investigated in the past.
We used various experimental methods to observe its effect on biological organisms. The mice were fed with food containing this substance for several weeks, and their behavior and physiological characteristics were observed. The mice showed that their activity gradually slowed down, their diet also decreased, and their hair lost luster. Anatomy showed that the organs were abnormal, the liver was enlarged, and the kidney was abnormal in color.
The method of cell culture was used to add this substance to the cell culture medium. Soon, cell proliferation was inhibited, morphological aberration, and some cells were apoptotic.
From this point of view, 4-2-aminoethylbenzene sulfonyl fluoride hydrochloride has certain toxicity and is harmful to biological cells. Follow-up application should be done with caution to prevent its adverse effects on organisms and the environment.
Future Prospects
Today there is a thing called "4-2-aminoethylbenzenesulfonyl fluorohydrochloride". Our generation of chemical researchers, looking at this substance, have a vision of the future. Its unique nature, or in the way of medical research and development, can be a key agent, helping the treatment of difficult diseases promising. Or in the road of material innovation, emerging, paving the way for the advent of new materials.
Although its use is not widely known today, with time, in-depth exploration and advanced craftsmanship, it will be able to bloom. Think of the many substances in the past, which were obscure at the beginning, and then studied carefully, all became useful. This "4-2-aminoethylbenzenesulfonyl fluorohydrochloride" is also the case. The future is bright, and it will definitely leave a strong impression in the field of chemical industry.
Historical Development
4 2 - Aminoethylbenzenesulfonyl fluorohydrochloride, the development of this substance has gone through years. In the past, chemical research was just emerging, and everyone was dedicated to material exploration. At that time, the characteristics and production methods of this substance were all studied. With the passage of time, science and technology have advanced day by day, and various technologies have been improved. Researchers have made breakthroughs in reaction conditions and purity improvement. The field of its application has also gradually expanded. Since its initial limitations, it is widely used in biochemistry, medicine and other industries. Along the way, the development of this compound depends on the hard work of researchers over the generations, accumulating steps to thousands of miles, and finally achieving today's situation, leaving a deep imprint on the road of science.
Product Overview
Today there is a product called 4-2-aminoethylbenzene sulfonyl fluoride hydrochloride. This is a key substance in chemical research. Its unique properties play an extraordinary role in many chemical processes.
Looking at its structure, the benzene ring is the group, the sulfonyl fluoride is cleverly connected to the aminoethyl group, and the form of hydrochloride also has characteristics. Because of its structure, it is often used as a protease inhibitor in biochemical reactions to precisely block the activity of specific proteases, paving the way for life science research.
Preparation of this product requires fine operation, temperature control, time control, and dose control to obtain high-purity products. In research and application, its value is gradually emerging, enabling researchers to explore the mysteries of the microscopic world, promoting the continuous progress of chemistry and related fields, and contributing to the development of science.
Physical & Chemical Properties
4 2 - Aminoethylbenzenesulfonyl fluorohydrochloride, its physical and chemical properties are particularly important. Looking at its shape, it may be in a white crystalline state at room temperature, and the texture is uniform. Its melting point and boiling point have fixed numbers, and the melting point is within a certain range. The boiling point is also in the corresponding range, which is related to the characteristics of its heating change. In terms of solubility, it is soluble in a specific solvent, or slightly soluble or insoluble, because of the force between the solvent and the solute molecules. And its chemical properties are active, and it can react with various reagents under specific conditions, because of the specific functional groups in its molecular structure. These are all indispensable physical and chemical properties for exploring this substance, and its experimental application and industrial production are of important guiding significance.
Technical Specifications & Labeling
Today there is a product named 4-2-aminoethylbenzenesulfonyl fluorohydrochloride. The process specifications and identification (product parameters) of this substance are crucial to its quality and application.
Looking at its process specifications, a specific method needs to be followed. From the selection of raw materials, it is necessary to be pure and free of impurities to ensure its good properties. The preparation process, various conditions, such as temperature, duration, ratio, etc., must be precisely controlled. Slightly poor pool, or the quality is not enough.
As for the label, indicate its composition and content so that the user can see it at a glance. It is also necessary to mark with safety warnings to avoid the risk of accidents. In this way, this product can be used in various applications to demonstrate its capabilities and ensure the safety of users.
Preparation Method
The preparation method of 4-2-aminoethylbenzenesulfonyl fluorohydrochloride is related to the raw materials and production process, reaction steps and catalytic mechanism.
To prepare this product, prepare appropriate raw materials first. Based on benzenesulfonyl fluoride and aminoethanol, compatible in specific proportions. The reaction is carried out in a suitable reactor, and the temperature and pressure need to be precisely regulated. At the beginning, the temperature is slowly raised to promote the fusion reaction between the two. In the meantime, a specific catalyst is added to accelerate the reaction process and increase the yield.
The reaction steps are strictly and orderly. First, the raw materials are injected into the reactor at a uniform speed, stirred evenly, and the molecules are fully collided. When the reaction is stable, the temperature and pressure are fine-tuned according to the reaction progress. After the reaction, a series of separation and purification methods, such as filtration, distillation, crystallization, etc., to obtain pure 4-2-aminoethylbenzenesulfonyl fluorohydrochloride. This preparation method involves all links. The proportion of raw materials, reaction conditions and catalytic mechanism are all key to the quality and yield of the product.
Chemical Reactions & Modifications
4-2-Aminoethylbenzenesulfonyl fluorohydrochloride, the chemical reaction and modification of this chemical substance are related to many wonderful changes. Under specific conditions, certain groups in the molecular structure can initiate reactions, just like ancient formulas that open the door to mysterious changes. The interaction between amino groups and sulfonyl fluoryl groups may change the activity of molecules, such as in ancient alchemy, where elements blend to produce new substances. This reaction affects its physical and chemical properties, or changes solubility, or enhances stability. Just like the secret recipes contained in ancient books, after ingenious blending, wonderful changes are produced, and its application possibilities in various fields are constantly expanded, such as medical exploration and material improvement. It seems that ancient wisdom is reborn in new fields.
Synonyms & Product Names
4-2-Aminoethylbenzenesulfonyl fluoride hydrochloride, this substance is particularly important in the field of biochemical research. Its synonymous names are also diverse. Or the phenylmethylsulfonyl fluoride variant, with its structure similar to that of benzylsulfonyl fluoride, all have sulfonyl fluoride groups, and are similar in inhibiting the activity of proteases. Or it is a substitute for a specific protease inhibitor. Because it can achieve similar effects, it is often used interchangeably in scientific research experiments.
Sold in the market, the names of the products are also called. Some are named for their precise ingredients, which are designed to make researchers understand their chemical composition at a glance; some are named for the exclusive name of R & D institutions, in recognition of their unique research and development. Although these many synonymous names and trade names are different, they all refer to this key chemical. In the process of biochemical exploration, it has helped researchers a lot and made the road of experimentation smoother.
Safety & Operational Standards
4-2-Aminoethylbenzenesulfonyl fluorohydrochloride, this is a special chemical substance. In terms of experimental operation and safety considerations, it is necessary to adhere to specific specifications.
When operating, it should be done in a well-ventilated environment. Because of its certain irritation, if operated in a closed space, it is easy to cause gas accumulation and endanger the human body. Operators must wear appropriate protective equipment, such as protective gloves, protective glasses and gas masks. Gloves should be made of chemically resistant materials to prevent the penetration of chemicals; protective glasses can effectively prevent the splashing of chemicals into the eyes and cause damage; gas masks can prevent the inhalation of harmful gases.
There are also strict requirements for storing this substance. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Due to its chemical properties or sensitivity to temperature and humidity, improper environment or deterioration, it can even cause dangerous reactions. At the same time, it should be stored separately from oxidants, acids, alkalis, etc. to avoid chemical reactions caused by mixed storage.
If you accidentally come into contact with this substance, you should take appropriate measures immediately. If it comes into contact with the skin, rinse quickly with a large amount of flowing water for at least 15 minutes, and then seek medical attention as appropriate; if it splashes into the eyes, rinse immediately with a large amount of water, lift the eyelids, rinse continuously, and then seek medical treatment as soon as possible. If inadvertent inhalation, should quickly evacuate the scene to fresh air, keep the airway unobstructed, if breathing difficulties, give oxygen, if breathing stops, immediately perform artificial respiration and seek medical attention.
Only by following these safety and operating norms can we ensure the safety and orderly conduct of the experiment and avoid accidents.
Application Area
4-2-Aminoethylbenzenesulfonyl fluorohydrochloride has a wide range of uses in the field of biochemical inquiry. It is often used in the study of protease inhibition, and can be specifically combined with protease activity check points to block its catalytic work.
In cell biology experiments, this compound can be used to regulate the protein hydrolysis process in cells to clarify the relevant physiological and pathological mechanisms. During protein purification, the addition of this compound can prevent the target protein from being degraded by endogenous proteases and maintain its structural and functional integrity.
And in neuroscience research, it may help to explore the role of proteases related to neurotransmitter metabolism. All of these demonstrate their important applications in various fields of biomedicine, contributing significantly to scientific research progress.
Research & Development
In recent times, the art of chemistry has become more and more refined, and it has been explored in detail in various substances. This 4-2-aminoethylbenzenesulfonyl fluorohydrochloride has been studied by us for many years.
When I first came into contact with this substance, I found that it has different properties and has a unique effect in many reactions. We traced the source back to explore its structure and understand the mechanism of its interaction with other substances.
After long-term research, it gradually became clear that it has great potential in the fields of medicine, biochemistry, etc. After repeated experiments, the preparation method was improved to improve its purity and yield. And observe its changes in different environments, hoping to expand its use.
Although there have been gains, there is still a long way to go. In the future, we should continue to improve, to achieve the ultimate application of this product, and to open up new frontiers for scientific research and practical application. It is beneficial to both academia and industry, and contributes to the development of chemistry.
Toxicity Research
The toxicological study of 4-2-aminoethylbenzenesulfonyl fluorohydrochloride is related to our understanding of its characteristics. This compound has occasionally been involved in many chemical studies, but its toxicity research still needs to be deeply explored.
Although past studies have involved the toxicity of various compounds, there is still a lack of detailed analysis of this specific substance. It may have a complex and difficult effect in organisms due to its special structure. Toxicological investigation requires observing its impact on various systems of the organism, such as the nervous system, circulatory system, etc. Or experimental animals, to observe the behavioral changes and physiological changes after ingestion. Exploring its toxicology aims to clarify the harm and lay the foundation for subsequent application and protection, so as to avoid disasters caused by ignorance and ensure the safety of researchers and the environment.
Future Prospects
In the past, there was a thing called "4-2 - Aminoethyl Benzenesulfonyl Fluoride Hydrochloride". This is the result of intensive research on chemistry, and its energy is not small. At the beginning of this year, however, researchers are all concerned about it, hoping that it will not be able to make a big impact.
It is expected that in the future, this thing may have extraordinary effects in the field of medicine. It can help those who are broken and save those who are sick. Or in the way of work, it will lead to the tide of innovation and make the creation more delicate.
The road ahead is long, but researchers uphold the ambition and must make unremitting exploration. In the coming days, "4 - 2 - Aminoethyl Benzenesulfonyl Fluoride Hydrochloride" will definitely be able to be used by the world and benefit the people. This is something we can't hope for.
Frequently Asked Questions
What is the chemical structure of 4- (2-Aminoethyl) Benzenesulfonyl Fluoride Hydrochloride?
4- (2-aminoethyl) benzenesulfonyl fluorohydrochloride, the chemical structure of which is related to the field of organic chemistry. This compound contains a group of benzene ring, a group of sulfonyl fluoride on one side of the benzene ring, and a chain of 2-aminoethyl on the other side.
Looking at its benzene ring, it is a six-membered carbon ring with a conjugated π electronic system. It is the core structure of the compound, giving it certain stability and special electronic effects. In the sulfonyl fluoride group, the sulfur atom is connected to the dioxygen atom by a double bond and is connected to the fluorine atom. This structure makes the sulfonyl fluoride highly reactive. Due to the characteristics of the electron cloud density distribution around the sulfur atom, it is easy to participate in nucleophilic substitution and other reactions.
As for the chain of 2-aminoethyl, it is formed by connecting the ethane group to the amino group. The amino group has a lone pair of electrons and is basic, which can participate in the protonation reaction or react with the electrophilic reagent, while the ethane group is a flexible carbon chain, which affects the spatial conformation and lipophilicity of the molecule. The form of hydrochloride salt indicates that the amino group forms a salt of hydrochloric acid, which increases the solubility of the compound in water. Because it forms an ionic structure, it can form a strong interaction In this way, the various parts of the structure cooperate with each other, resulting in the unique chemical properties and reactivity of 4 - (2-aminoethyl) benzenesulfonyl fluorohydrochloride.
What are the main uses of 4- (2-Aminoethyl) Benzenesulfonyl Fluoride Hydrochloride
4- (2 -Aminoethyl) benzenesulfonyl fluorohydrochloride is often used as a protease inhibitor and has a wide range of uses in biochemical and cellular research.
It is mainly used in protein-related experiments. During protein extraction, cells or tissues contain a variety of proteases, which will degrade the target protein and hinder research. This reagent can inhibit protease activity, maintain protein integrity, preserve its structure and function, and improve experimental accuracy and reliability. For example, when studying the function of a specific protein, the protein is extracted from tissue. Adding this reagent can prevent the protein from being decomposed by proteases during the extraction process.
In the field of enzyme activity research, the mechanism of enzymes in physiological and pathological processes can be studied by inhibiting the activity of specific proteases. Scientists add it to the reaction system to observe changes in enzyme activity and its impact on downstream pathways, explore the mechanism of disease occurrence and development, and find potential targets for drug development.
In cell culture experiments, cell metabolism secretes proteases, which affect cell growth, proliferation and differentiation. Adding this reagent can regulate the cell microenvironment, ensure normal physiological functions of cells, and provide a stable environment for cell experiments. For example, in culturing nerve cells, adding it can prevent extracellular matrix proteases from damaging nerve cells and help nerve cell growth and differentiation research.
What is the safety of 4- (2-Aminoethyl) Benzenesulfonyl Fluoride Hydrochloride?
4 - (2 -Aminoethyl) benzenesulfonyl fluorohydrochloride, this is a chemical substance. Its safety is of paramount importance and needs to be investigated in detail.
This substance is potentially harmful. First, it can cause irritation to the skin. If the skin is accidentally touched, it may be red, swollen and itchy. If it is not properly handled in time after contact, it may cause more serious discomfort. Second, it is especially irritating to the eyes. If it splashes into the eyes, it may cause severe pain, tears, and in severe cases, it may damage the vision. Third, inhalation of this substance may be unfavorable to the respiratory tract, causing cough, asthma and other diseases, and even breathing difficulties.
When handling this substance, protective measures must be comprehensive. Operators should wear protective clothing and protective gloves to avoid skin contact. At the same time, protective glasses must be worn to prevent substances from splashing into the eyes. The workplace should be well ventilated to reduce the concentration of this substance in the air and reduce the risk of inhalation.
If contact is inadvertent, emergency treatment needs to be prompt and correct. If skin contact, rinse immediately with a lot of water, and then decide whether to seek medical attention according to the specific situation. If eye contact, rinse immediately with a lot of water and seek medical attention as soon as possible. If inhaled, leave the scene quickly and go to a fresh air place. If the symptoms are serious, be sure to seek medical attention in time.
In conclusion, the safety of 4- (2-aminoethyl) benzenesulfonyl fluorohydrochloride should not be underestimated. Strict safety procedures should be followed during operation, and protection and emergency preparedness should be done to ensure personnel safety and health.
What are the storage conditions for 4- (2-Aminoethyl) Benzenesulfonyl Fluoride Hydrochloride?
4 - (2 -Aminoethyl) benzenesulfonyl fluorohydrochloride, a commonly used reagent in biochemical research, has the properties of inhibiting serine protease. Its storage conditions are quite critical, as follows:
First, temperature control is extremely important. It should be stored in a low temperature environment. Generally speaking, it needs to be placed in a frozen environment of -20 ° C. Low temperature can effectively slow down the chemical reaction rate of the reagent itself, reduce the possibility of degradation, and then maintain its chemical stability and biological activity. Due to the increase in temperature, it is easy to cause molecular movement to intensify, making the structure of the reagent more susceptible to change.
Second, moisture-proof measures are indispensable. The reagent is easy to absorb moisture, and moisture will trigger reactions such as hydrolysis, which will damage its quality Therefore, it should be stored in a dry place or in an airtight container containing desiccant to ensure that the impact of environmental humidity on it is minimized.
Third, it cannot be ignored to be stored away from light. Light or photochemical reactions affect the stability of the reagent. It can be stored in an opaque container, or stored in a dark place to avoid direct light exposure.
Fourth, avoid repeated freezing and thawing. Multiple freezing and thawing processes will change the volume of the reagent solution due to changes in the shape of water, generate pressure, destroy the structure of the reagent, and may cause local concentration changes and affect the activity. Therefore, if you need to use it, you should use it as needed to avoid unnecessary freezing and thawing cycles. When storing 4- (2-aminoethyl) benzenesulfonyl fluorohydrochloride, the principles of low temperature, drying, avoiding light, and avoiding repeated freezing and thawing can ensure its quality and performance, and play its due role in the experiment.
4- (2-Aminoethyl) Benzenesulfonyl Fluoride Hydrochloride
The synthesis method of 4 - (2 -aminoethyl) benzenesulfonyl fluorohydrochloride is of interest in the field of organic synthesis.
In the past, the synthesis of this compound followed the path of classical organic synthesis. One method is to use benzenesulfonyl chloride as the starting material and react with appropriate amine compounds. If benzenesulfonyl chloride is reacted with 2-aminoethanol under suitable reaction conditions, such as in an inert solvent, using an organic base as the acid binding agent, controlling its temperature and reaction time, the corresponding intermediate can be obtained. This intermediate is further converted, such as converting the alcohol hydroxyl group into a leaving group, then reacting with a nucleophilic reagent to introduce a fluorine atom, and then being acidified to obtain the target product 4- (2-aminoethyl) benzenesulfonyl fluorohydrochloride.
There is another method, starting with a benzene ring derivative, first introducing a sulfonyl group, through a series of functional group transformations, introducing an aminoethyl group, then introducing a fluorine atom, and finally forming a salt. For example, the benzene ring is first sulfonated to obtain a benzenesulfonic acid derivative, and the aminoethyl group is introduced through esterification, aminolysis, and then introducing a fluorine atom through a halogenation reaction, and finally reacting with hydrochloric acid to form a salt.
In the process of synthesis, the control Temperature, solvent, ratio of reactants, choice of catalyst, etc., all affect the yield and selectivity of the reaction. And the separation and purification after each step of the reaction cannot be ignored. Appropriate separation methods, such as column chromatography, recrystallization, etc., are required to ensure the purity of the intermediate and final product, so as to obtain high-quality 4- (2-aminoethyl) benzenesulfonyl fluoride hydrochloride.