3 Nitrobenzotrifluoride
Fluoride

3-Nitrobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

909806

Chemical Formula C7H4F3NO2
Molecular Weight 191.107 g/mol
Appearance Colorless to yellow liquid
Odor Pungent odor
Boiling Point 203 - 204 °C
Melting Point -27 °C
Density 1.434 g/mL at 25 °C
Solubility In Water Insoluble
Vapor Pressure 0.22 mmHg at 25 °C
Flash Point 88 °C
Refractive Index 1.4865 (20 °C)
Packing & Storage
Packing 500 - gram bottle of 3 - Nitrobenzotrifluoride, well - sealed for chemical safety.
Storage 3 - Nitrobenzotrifluoride should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames. It should be kept in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reducing agents to avoid potential chemical reactions. Use appropriate storage cabinets or areas designated for hazardous chemicals.
Shipping 3 - Nitrobenzotrifluoride is shipped in accordance with strict hazardous material regulations. It's typically transported in specialized containers, ensuring secure transit to prevent leaks and uphold safety during shipping.
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3-Nitrobenzotrifluoride
General Information
Historical Development
3 nitrotrifluorotoluene is also an organic compound. It is gradually becoming more and more important in chemical substances. In the past, chemistry was at the beginning of its rise, and it was fresh to study this substance. However, with the advance of science and technology, scholars are gradually observing its properties and uses.
At the beginning, exploring the method of its synthesis encountered many difficulties. All kinds of attempts, or the diameter, or the yield is quite low. After years of study, the technique has become more refined, the synthesis method has become better, and the yield has also been improved.
Today, 3 nitrotrifluorotoluene is widely used in medicine, pesticides and other industries. Looking at its historical development, it has been emphasized by the industry since few people have been interested in it. It is really due to the diligent research of scholars of all dynasties that they have obtained this entry and developed their extraordinary capabilities in the field of chemical industry.
Product Overview
3-Nitrotrifluorotoluene is also a chemical substance. Its color may be absent, the shape is like a liquid, and it has a special odor. The boiling point is quite different, and the properties are relatively stable at room temperature.
This substance is widely used in the chemical industry. It can be used as a key raw material for the synthesis of medicine, pesticides, dyes, etc. In the synthesis of medicine, it can help to become a special drug; in the preparation of pesticides, it can be used to make an efficient insecticidal and sterilization agent; in the production of dyes, it is bright and lasting.
However, it also needs to be handled with caution. It has certain toxicity. If it touches the human body, smells it or eats it, it may harm health. When operating, it must follow strict procedures and prepare proper protective equipment to prevent leakage. Storage should be in a cool, dry and well ventilated place to avoid fire and heat. In this way, the material can be used safely and effectively for the development of chemical industry.
Physical & Chemical Properties
The physicochemical properties of 3-nitrotrifluorotoluene are related to the research of scholars and are quite important. This substance is a colorless to light yellow liquid with a pungent odor. Its boiling point is about 187-188 ° C, and its density is higher than that of water, which is 1.492g/cm ³.
Its solubility also has characteristics. It is slightly soluble in water, but it can be miscible with organic solvents such as ethanol and ether. At the chemical end, 3-nitrotrifluorotoluene has the characteristics of nitro and trifluoromethyl. Nitro is active and can participate in many reactions, such as reduction reactions, and can be converted into amino groups. Trifluoromethyl gives it special stability and hydrophobicity. The combination of the two makes the substance a key intermediate in the field of organic synthesis and is widely used. Therefore, its physicochemical properties are essential for research and exploration.
Technical Specifications & Labeling
3-Nitrotrifluorotoluene is an important chemical raw material. Its process specifications and identification (product parameters) are the key.
In terms of process specifications, the synthesis of this product requires a specific reaction process. In a suitable reaction vessel, put the raw materials in a precise ratio and control the temperature, pressure and other conditions. If the reaction temperature should be maintained in a certain range, the pressure should also conform to a specific value, so as to ensure the smooth progress of the reaction and improve the purity and yield of the product.
For the identification (product parameters), various indicators should be clearly marked. For example, the purity should meet a certain standard, and the impurity content must be strictly limited. Appearance color, physical properties, etc. should also be clearly marked so that users can clearly know the characteristics of the product and ensure that it achieves the desired effect in subsequent applications. Therefore, it meets the rigorous requirements of chemical products.
Preparation Method
The method of making 3-Nitrobenzotrifluoride is related to the raw materials and production process, reaction steps and catalytic mechanism. The common raw materials include a halogenated aromatic hydrocarbon and a fluorine-containing reagent. First, the halogenated aromatic hydrocarbon and the fluorine-containing reagent are mixed in a special container, controlled at a suitable temperature, about a certain interval, and a catalyst is added. This catalyst can promote the reaction speed. The reaction steps are as follows: At the beginning, the two slowly combine, the molecular structure gradually changes, and after several conversions, the fluorine atom gradually enters the halogenated aromatic hydrocarbon structure to obtain the intermediate product. Then, the intermediate product is reacted and then the conditions are adjusted, such as variable pressure and temperature fine-tuning, and finally 3-Nitrobenzotrifluoride. The catalytic mechanism is that the catalyst activity check point interacts with the reactants to reduce the activation energy of the reaction and make the reaction easy to progress. This method has been repeatedly tested to be efficient and stable to meet the needs of production.
Chemical Reactions & Modifications
There are chemical things today, named 3-Nitrobenzotrifluoride. In chemical reactions, its properties can be investigated.
This substance, the state of the reaction, is related to many factors. Its participation in the reaction, the rate may be slow or urgent, and the product varies depending on the conditions. In the past, everyone sought the usual reaction, and then gradually thought about changing it, hoping to change its properties to suit the needs of the public.
If you want to change its properties, you should study the reaction mechanism. Observe the structure of its molecules, know the strength of its bonds, and understand the cloud of electrons. In this way, you can find a way to change. Try different temperatures, pressures, and solvents to observe the change of the reaction. Or add catalytic substances to promote its activity and make the reaction go to the desired direction. After various attempts, I hope to get the best method and change the 3-Nitrobenzotrifluoride nature, so that in the fields of industry and scientific research, it can develop its growth and increase its effectiveness.
Synonyms & Product Names
3 - Nitrobenzotrifluoride, this substance is also called nitrotrifluorotoluene. In the field of chemical industry, its names are different, but they all refer to the same substance.
We have studied this substance for a long time, and we know the complexity of its aliases. There are those who call it by its chemical structure characteristics, and there are those who name it according to industry habits. Although the names are different, they actually refer to this 3-Nitrobenzotrifluoride.
Guanfu ancient books, although there is no such precise modern chemical name, the evolution of chemical industry has made today's names numerous. When we study this substance, we need to understand its various different names in order to accurately explore its properties and uses. Or in organic synthesis, or in the preparation of materials, it is necessary to determine their various names to avoid confusion and make mistakes in research.
Safety & Operational Standards
3-Nitrotrifluorotoluene Safety Production and Operation Specifications
#1. Raw Material Characteristics
3-Nitrotrifluorotoluene, the properties are colorless to light yellow liquid, with an irritating odor. It is strongly oxidizing and corrosive, flammable in case of open flame and hot topic, and can react violently with reducing agent. It decomposes by hot topic and releases toxic gases, which are irritating to eyes, respiratory mucosa and skin.
#2. Production Operation Specifications
1. ** Reaction Process **
- The reaction equipment needs to be made of corrosion-resistant materials, such as enamel reactors or stainless steel materials and the inner wall is specially treated. Before feeding, be sure to check the sealing and cleanliness of the equipment to prevent impurities from mixing and affecting the reaction or causing safety accidents.
- Strictly control the reaction temperature and pressure. According to the reaction characteristics, the temperature is maintained at [specific temperature range] and the pressure is controlled at [specific pressure range] with a precise temperature control system. If the temperature and pressure are abnormal, quickly start the emergency cooling and pressure reduction device to prevent the reaction from getting out of control.
- The order and speed of feeding are strictly carried out according to the process requirements. Put in [specific raw material 1] first, stir well, and slowly add [specific raw material 2] to control the feeding speed and prevent the reaction from being too violent.
2. ** Separation and Purification **
- During the distillation operation, select the appropriate distillation equipment and conditions. Determine the distillation temperature and vacuum degree according to the boiling point and impurity characteristics of 3-nitrotrifluorotoluene. The distillation process closely monitors the temperature and vacuum degree changes to avoid the phenomenon of flushing, boiling, etc.
- In the extraction and separation, select the appropriate extractant to ensure the extraction effect and safety. Pay attention to the stratification situation during the extraction process, accurately collect the target product layer, and prevent the mixing of impurities.
#3. Safety protection measures
1. ** Personal protection **
- Operators must wear comprehensive protective equipment, including acid and alkali protective clothing, protective gloves, protective glasses and gas masks. Before entering the production area, make sure that the protective equipment is worn correctly and in good condition.
2. ** Equipment Safety **
- Install a complete ventilation system to ensure the air circulation in the production workshop and discharge toxic and harmful gases in time. Regular maintenance and inspection of ventilation equipment to ensure its normal operation.
- Configure fire protection facilities, such as fire extinguishers, fire sand, etc., and organize fire drills regularly to ensure that employees are proficient in the use of fire equipment.
- Electrical equipment is selected explosion-proof type, and grounding and leakage protection devices are set to prevent fires and explosions caused by electrical failures.
3. ** Emergency Response **
- Develop detailed emergency plans and formulate specific response measures for leaks, fires, poisonings and other accidents. Regularly organize emergency drills to improve employees' emergency response capabilities.
- In the event of 3-nitrotrifluorotoluene leakage, immediately evacuate the scene personnel to a safe area and cut off the fire source. Emergency personnel wear protective equipment and use inert materials such as sand and vermiculite to absorb the leakage to avoid it flowing into restricted spaces such as sewers.
Application Area
3-Nitrotrifluorotoluene is an important product of chemistry. Its application field is quite wide. In the field of medicine, it can be used as a key raw material for synthesizing specific drugs, and it can help doctors make good medicines to cure diseases. In terms of pesticides, it can contribute to the creation of high-efficiency pesticides, protect agricultural products from pests, and ensure the fertility of crops. In the material industry, it can be used to develop new materials to make materials with specific properties, such as better weather resistance and wear resistance. In the dye industry, or as an essential agent for making beautiful and long-lasting dyes, dyes and textures are colorful. All of these are essential for the application of 3-nitrotrifluorotoluene in all aspects, and it is indispensable in the field of chemistry.
Research & Development
In modern times, chemistry has advanced, and the research of substances has deepened. 3 - Nitrobenzotrifluoride This substance has been studied by scholars. At the beginning, its preparation was difficult and the yield was quite low. However, everyone worked hard, and repeatedly explored the reaction conditions and the ratio of raw materials. After years of work, it has gradually obtained optimization methods, and the yield has also steadily increased.
At the application end, 3 - Nitrobenzotrifluoride was only seen in niche experiments at first. Later, due to its unique properties, it has emerged in the fields of medicine and materials. Medicine assists in the research and development of new drugs, and materials promote the creation of new products.
Today, its research has not dared to stop a little. Scholars hope that the synthesis path will be simpler, the efficiency will be better, and the application will be wider. Innovation, unremitting, looking forward to the future, shining, used by the world, to promote the progress of chemistry, blessing all people.
Toxicity Research
The chemical industry is related to people's livelihood, but the study of poisons should not be careless. Today there are 3-Nitrobenzotrifluoride of this substance, and the study of its toxicity is very important.
To observe its physical properties, or have a stimulating effect, it will harm the viscera and meridians when entering the body. Inhaling it through the mouth and nose, or seeping it through the skin, can cause disease. In the experimental place, we observed its impact on the living beings. The mice were dyed, hyperactive and then sluggish, the diet was gradually wasted, and the viscera were also abnormal.
Our research on the toxicity of this substance aims to clarify its harm and prevent it before it occurs. Make workers aware of its risks, use it carefully, and prepare protective equipment. Do not let poisons hurt the body. I also hope that the industry will focus on the research of toxicity, keep the way of safety, and ensure the well-being of everyone. This is our responsibility.
Future Prospects
3 - Nitrobenzotrifluoride This product is unique in nature and has a wide range of uses. It has already emerged in the current chemical industry. Although it is currently used, there is still a vast space for future development.
In the future, the process may be refined, the cost will be reduced, and the yield will increase. It can be used as a key raw material in the creation of medicine, and it can be used as a magic medicine to cure diseases. In the research and development of materials, it may be able to introduce new materials and produce strange materials for use in the field of high-tech.
Or expand its application and get involved in emerging industries, such as new energy and electronics. With time, it will be able to shine brightly, contribute to the progress of the world, and become the pillar of future chemical development, leading the industry forward and reaching an unprecedented level.
Frequently Asked Questions
What are the main uses of 3-Nitrobenzotrifluoride?
3-Nitrotrifluorotoluene has a wide range of uses. In the field of organic synthesis, it is a key intermediate. It can participate in many chemical reactions, such as nucleophilic substitution reactions, and can introduce other groups to form complex organic compounds. In the creation of pesticides, with its unique chemical structure, it can be used to prepare pesticides with high insecticidal, bactericidal or herbicidal properties. Because of its specific electronic effect and spatial structure, it endows pesticides with excellent biological activity and environmental adaptability. In the field of pharmaceutical research and development, it also plays an important role. It can be used as a starting material to prepare drugs for treating specific diseases through a series of chemical reactions. Due to its certain characteristics, it is beneficial to interact with biological targets, or affect the absorption, distribution, metabolism and excretion process of drugs, thereby improving the efficacy and safety of drugs. In the field of materials science, 3-nitrotrifluorotoluene can be used to synthesize polymer materials with special properties. For example, the polymers involved in the synthesis may have good heat resistance, chemical stability and electrical properties, and are suitable for electronic devices, aerospace and other fields that require strict material properties. In short, 3-nitrotrifluorotoluene has important application value in many fields such as organic synthesis, pesticides, medicine and materials science, and promotes the development and progress of related industries.
What are the physical properties of 3-Nitrobenzotrifluoride?
3 - Nitrobenzotrifluoride is an organic compound with unique physical properties, let me tell you in detail.
This substance is mostly liquid at room temperature, and it is clear and transparent, colorless or slightly yellow. It has a certain volatility and can be slowly emitted around it when placed in the air. The boiling point is about 207 ° C. Under normal air pressure, it needs to reach this temperature to boil into a gaseous state. The melting point is about -27 ° C. If the temperature drops below this point, it will solidify into a solid state.
3 - Nitrobenzotrifluoride has a density greater than that of water. When mixed with water, it will sink to the bottom of the water. It is difficult to dissolve in water. Due to the structural characteristics of molecules, it is difficult to form effective interactions with water molecules. However, in organic solvents, such as ethanol, ether, acetone, etc., it has good solubility and can dissolve with these organic solvents to form a uniform mixed system.
Furthermore, it has a special smell, although it is not stinky and pungent, it also has a unique smell, and the smell is discernible. And this material is a poor conductor of electricity. It has little electrical conductivity in terms of circuit conduction, etc., because there is no free-moving charge carrier in its molecular structure.
From the above, the physical properties of 3-Nitrobenzotrifluoride are of great significance in chemical experiments, industrial production and related fields, related to its separation, purification, storage and use.
What is the chemistry of 3-Nitrobenzotrifluoride?
3-Nitrotrifluorotoluene has strong and active properties, and often shows a unique state in the chemical environment. This is an aromatic hydrocarbon containing nitro and trifluoromethyl groups. Due to its unique structure, it has extraordinary properties.
It has high reactivity. The presence of nitro groups changes the electron cloud density of the benzene ring, making the electrophilic substitution reaction easy to go to a specific position. However, due to its strong absorption of nitro groups, aromatic rings are more sensitive, and may involve oxidation and reduction reactions under specific conditions. The introduction of
trifluoromethyl makes this compound have excellent chemical stability and hydrophobicity. This group has high electronegativity and increases molecular polarity, which has a great impact on intermolecular forces and solubility. It has good solubility in organic solvents, but it is difficult to dissolve in polar solvents such as water.
When heated or exposed to specific reagents, 3-nitrotrifluorotoluene may decompose, releasing toxic and corrosive gases. When it involves reaction, it is necessary to carefully control the conditions to ensure safety and efficiency. In organic synthesis, it is often an important raw material for the preparation of fluorine-containing fine chemicals, pharmaceuticals, pesticides and other important raw materials. With its particularity, it can build complex and useful molecular structures.
What are the preparation methods of 3-Nitrobenzotrifluoride?
There are various ways to prepare 3-nitrotrifluorotoluene. First, trifluorotoluene is used as the beginning, and it can be obtained by nitrification. When trifluorotoluene encounters a mixed acid of concentrated nitric acid and concentrated sulfuric acid, under suitable temperature and pressure, nitrate acts as an electrophilic reagent to attack the benzene ring to obtain 3-nitrotrifluorotoluene. Among them, the proportion of mixed acid and temperature control are crucial. If the temperature is too high, side reactions will occur and the product will be impure; if the temperature is too low, the reaction will be slow and time-consuming.
Second, 3-amino trifluorotoluene is prepared by diazotization and nitrification. First, 3-amino trifluorotoluene is diazotized with sodium nitrite and hydrochloric acid to obtain diazonium salts. The diazonium salt has good activity, and then interacts with nitrite or nitric acid and other nitrifying agents to convert it into 3-nitrotrifluorotoluene. However, there are many steps in this route, and careful operation is required. The reaction conditions of each step are strictly controlled to maintain the yield and purity.
Third, m-nitrobenzoic acid is used as a group to react with fluorinated reagents. M-nitrobenzoic acid and fluorinating agents such as trifluoroacetic anhydride, etc., with the help of catalysts, the carboxyl group is converted into trifluoromethyl, and then 3-nitrotrifluorotoluene is obtained. The raw materials in this way are easy to find, but the fluorinating agents are often toxic and corrosive, which requires strict equipment and safety protection.
The method of preparing 3-nitrotrifluorotoluene has advantages and disadvantages. In practical operation, it is necessary to weigh and choose the appropriate method according to many factors such as the availability of raw materials, cost accounting, and product requirements.
3-Nitrobenzotrifluoride what are the precautions during use
3-Nitrotrifluorotoluene is a commonly used raw material in organic synthesis. When using it, many precautions must be observed.
First, this substance is toxic and harmful to the human body. When touching, be careful. If you inhale its vapor inadvertently, it may cause respiratory discomfort and even damage the lungs. Contact with the skin may cause allergies, burns, etc. Therefore, when operating, wear protective gloves and masks in front of protective clothing to prevent its harm.
Second, 3-Nitrotrifluorotoluene is flammable. In case of open flames and hot topics, it is very easy to burn and explode. Store away from fire and heat sources and keep well ventilated. During the handling process, it should also be handled with care to avoid sparks due to collision and friction, which may cause danger.
Third, its chemical properties are lively. It can react chemically with many substances. In experiments or production, when compatible, it is necessary to check its chemical properties in detail to prevent improper reactions. If mixed or mixed with reducing substances, or cause violent reactions, serious consequences will result.
Fourth, waste disposal also needs attention. It should not be discarded at will, and should be properly disposed of in accordance with relevant regulations. Because it may pollute the environment, it needs to go through professional processes to make it harmless and meet the requirements of environmental protection.
In short, when using 3-nitrotrifluorotoluene, it is necessary to be familiar with its characteristics, adhere to the operating procedures, and pay attention to safety protection and environmental protection requirements, so as to ensure the safety of operation and avoid accidents.