3 Nitro 5 Iodobenzotrifluoride
Fluoride
3-Nitro-5-Iodobenzotrifluoride
Chemical Formula C7H3F3INO2
Molecular Weight 329.003
Appearance Solid
Color Off - white to yellowish
Melting Point 57 - 61 °C
Solubility In Water Insoluble, as it is an organic compound with non - polar fluorinated and aromatic groups
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low, due to its solid state at room temperature
Stability Stable under normal conditions, but may react with strong reducing agents, bases
FAQ

What are the main uses of 3-Nitro-5-Iodobenzotrifluoride?

3-Nitro-5-iodotrifluorotoluene is also an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry. Due to its unique structure, it can be converted into bioactive compounds through various chemical reactions. It has a significant role in the process of drug development and can assist in the synthesis of new specific drugs.

In the field of materials science, it also has important uses. Because it contains special functional groups, it can be introduced into polymer materials to improve the properties of materials, such as enhancing their chemical stability and heat resistance, and then expand the application of materials in special environments.

In pesticide chemistry, 3-nitro-5-iodotrifluorotoluene can be used as a raw material for the synthesis of pesticides. After appropriate chemical modification, the prepared pesticide may have high insecticidal and bactericidal properties, and has little impact on the environment, which can provide a strong guarantee for agricultural production.

In addition, in the field of organic synthetic chemistry, it is an important starting material and participates in the construction of many complex organic molecules. With its lively chemical properties, it can open multiple synthesis paths, providing organic synthetic chemists with a wealth of choices to achieve the synthesis of various target compounds.

What are the physical properties of 3-Nitro-5-Iodobenzotrifluoride?

3 - Nitro - 5 - Iodobenzotrifluoride is an organic compound with unique physical properties. Its properties are usually liquid or solid, depending on the ambient temperature and pressure.

The melting point of this compound depends on its solid-liquid transition. At a specific temperature, it will melt from the solid state to the liquid state. However, the melting point data varies depending on the preparation method and purity.

The boiling point is also an important physical property. Under a specific pressure, the temperature at which a substance converts from liquid to gaseous state. 3 - Nitro - 5 - Iodobenzotrifluoride The boiling point is affected by factors such as intermolecular forces and molecular weight. Intermolecular forces are strong, and the boiling point is relatively high; the larger the molecular weight, the higher the boiling point may be.

The density reflects the mass of the substance per unit volume, and its density is related to the molecular structure and atomic weight. If the molecules are closely arranged and the atomic weight is large, the density will be higher. The density of this compound can help determine its position in the mixture, or be used for separation and purification.

Solubility is related to its solubility in different solvents. 3 - Nitro - 5 - Iodobenzotrifluoride As an organic compound, it may have some solubility in common organic solvents such as ethanol, ether, dichloromethane, etc. However, its solubility in water is due to the large difference in molecular polarity from water, or it is not good. Because water is a polar solvent, and the polarity of this compound is limited, it is difficult to dissolve in water according to the principle of "similar miscibility".

In addition, the physical properties of the compound such as volatility and odor are also of concern. Volatility refers to its ability to escape from liquid or solid state to gaseous state. Volatility affects its diffusion in the environment. Odor may be special. Although it is not an exact physical quantity, it can be used as a reference in identification and operation.

Understanding the physical properties of 3-Nitro-5-Iodobenzotrifluoride is of great significance for its synthesis, separation, storage and application. During synthesis, the reaction temperature is controlled according to its melting point and boiling point; when separating and purifying, the appropriate solvent is selected due to the difference in solubility; when storing, consider the properties of volatility and stability, and choose the appropriate conditions to ensure its quality and safety.

Is 3-Nitro-5-Iodobenzotrifluoride chemically stable?

3 - Nitro - 5 - Iodobenzotrifluoride is an organic compound. The stability of its chemical properties is crucial for the storage, transportation and use of this compound.

This compound contains nitro groups, iodine atoms and trifluoromethyl groups. Nitro groups have strong electron absorption, which can reduce the electron cloud density of the benzene ring, making the benzene ring more susceptible to attack by nucleophiles. At the same time, it also increases its reactivity and decreases its stability under certain conditions. For example, when encountering reducing agents, nitro groups are easily reduced and chemical reactions occur. < Br >
Although the iodine atom is a halogen atom, its C-I bond energy is relatively small and it is easy to break, so that the compound can participate in nucleophilic substitution and other reactions under specific conditions, which also affects its stability. For example, in an alkaline environment or in the presence of nucleophilic reagents, the iodine atom may be replaced.

Trifluoromethyl is a strong electron-absorbing group, which will further affect the distribution of benzene ring electron clouds and play a certain role in the stability of the compound. Because of its high electronegativity, it can enhance molecular polarity and affect intermolecular forces.

Overall, the chemical properties of 3-Nitro-5-Iodobenzotrifluoride are not stable. When storing, pay attention to isolating air, moisture and avoiding high temperature environments to prevent chemical reactions. When transporting, corresponding protective measures should also be taken to ensure that it is in a stable state to prevent chemical changes caused by external factors and endanger transportation safety.

What are 3-Nitro-5-Iodobenzotrifluoride synthesis methods?

The synthesis method of 3-nitro-5-iodotrifluorotoluene covers a variety of paths. First, it can be obtained from the starting material containing benzene ring through several steps such as nitrification and halogenation.

Initially, a suitable benzene derivative is taken, and the mixed acid system of concentrated nitric acid and concentrated sulfuric acid is used to carry out nitrification reaction at a specific temperature and reaction time. This process requires strict temperature control to prevent side reactions from breeding and resulting in impure products. After the nitrification reaction, a benzene derivative containing nitro groups is obtained.

Then, the nitrobenzene derivative is halogenated and iodine atoms are introduced. This step may require the selection of suitable halogenating reagents, such as iodine and appropriate oxidant combinations, or other special iodizing reagents. The reaction conditions also need to be carefully regulated, including the choice of solvent, reaction temperature and time, etc., to ensure that iodine atoms are precisely introduced into the target location and the yield is considerable.

Another way is to halogenate the benzene ring to obtain iodine-containing benzene derivatives, and then carry out the nitrification step. However, this path also has considerations. The localization selectivity of iodine atoms during halogenation and the effect of subsequent nitrification reactions on the introduced iodine atoms need to be carefully weighed.

Or it can start with other functionalized benzene series, and through multi-step functional group transformation, nitro groups, iodine atoms and trifluoromethyl groups can be introduced one after another. This strategy requires precise control of the sequence of reaction steps and reaction conditions in order to efficiently obtain the target product 3-nitro-5-iodotrifluorotoluene. Each method has its advantages and disadvantages. In the actual synthesis, the optimal synthesis path should be comprehensively selected according to many factors such as the availability of raw materials, the difficulty of reaction conditions, yield and purity requirements.

What is the price range of 3-Nitro-5-Iodobenzotrifluoride in the market?

The price of 3-nitro-5-iodotrifluorotoluene in the market is difficult to determine. This is due to the complex market conditions, and the price varies for many reasons.

First, the situation of supply and demand is the key. If there are many applicants and few suppliers, the price will often rise; on the contrary, if the supply exceeds the demand, the price may drop. If at some time many companies compete to buy this product for special purposes, such as the raw materials for fine chemical synthesis, the demand will increase sharply, and the price will rise; if the supplier's production capacity suddenly increases and the market is full, the price will fall.

Second, the price of raw materials will also be loud. The preparation of 3-nitro-5-iodotrifluorotoluene requires specific raw materials, and the fluctuation of raw material prices will be transmitted to the finished product. If the price of the required starting materials rises due to land disasters and supply shortages, the price of the 3-nitro-5-iodotrifluorotoluene will also follow.

Third, the difficulty of preparation is also related to the price. If its synthesis requires exquisite technology, harsh conditions, and expensive reagents, the cost is high and the price is not cheap; if the preparation process is improved, the cost will be reduced, and the price may be low.

Fourth, inter-market competition has a deep impact. If there are many people in the market competing to sell this product, it is a competition for customers, or there may be a price reduction; if it is exclusively supplied, it controls the right to price, and the price may be high.

Looking at the past "Tiangong Kaiwu", although it does not involve this product, it shows that the price of the product is not fixed. Today's 3-nitro-5-iodotrifluorotoluene is in the market, and the price may be between a few yuan and a few dozen yuan per gram. It is unknown. It depends on the changes of the above factors. Buyers should carefully observe the market conditions to get a good price.