3-Hydroxybenzotrifluoride

Duxiu Chemical

Specifications

HS Code	646145
Chemical Formula	C7H5F3O
Molar Mass	162.11 g/mol
Appearance	Colorless to light yellow liquid
Boiling Point	174 - 176 °C
Melting Point	1 - 3 °C
Density	1.325 g/cm³
Solubility In Water	Insoluble
Flash Point	65 °C
Vapor Pressure	0.67 kPa (20 °C)
Refractive Index	1.442 - 1.444

Packing & Storage

Packing	500g of 3 - Hydroxybenzotrifluoride packaged in a sealed, corrosion - resistant container.
Storage	3 - Hydroxybenzotrifluoride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture absorption and evaporation. It is advisable to store it in a dedicated chemical storage cabinet, separated from incompatible substances to avoid potential reactions.
Shipping	3 - Hydroxybenzotrifluoride is shipped in well - sealed, corrosion - resistant containers. It adheres to strict chemical transportation regulations, ensuring safe transit to prevent any leakage and potential environmental or safety hazards.

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General Information

Historical Development

3-Hydroxytrifluorotoluene is a chemical product. Its initial research and development was based on the academic research on the characteristics of fluorine-containing compounds. In the early years, Zhu Xian wanted to explore the changes caused by the introduction of fluorine-containing groups into organic molecules, so he paid attention to this.
The initial preparation method is cumbersome and inefficient, and only a small amount can be produced. With the passage of time, chemical technology has improved, and new synthesis methods have emerged. Chemists have worked hard to improve the reaction conditions and optimize the process.
From the initial exploration to the process of gradually forming a system, the output of 3-hydroxytrifluorotoluene has gradually increased, and its application has also become more and more widespread. From niche research in the laboratory to industrial production, it is used in materials, medicine and other fields. This is the process of unremitting scientific research and innovation.

Product Overview

3-Hydroxytrifluorotoluene is an important product of chemical research. Its unique properties are colorless to light yellow liquid with a specific odor.
This product is widely used in the chemical industry. In organic synthesis, it is often used as a key intermediate to assist in the preparation of many complex organic compounds. Because it contains special functional groups, it can participate in a variety of chemical reactions, laying the foundation for the synthesis of new materials, drugs, etc.
The preparation method often depends on a specific chemical process. Through a carefully designed reaction process, with suitable raw materials, catalysts and reaction conditions, the reaction is carried out in an orderly manner, so as to obtain high-purity 3-hydroxytrifluorotoluene.
However, the road to research also has challenges. It is necessary to precisely control the reaction conditions and improve the yield and purity of the product. Only by continuous research and optimization of the process can this product play a greater role in various fields and promote the vigorous development of the chemical industry.

Physical & Chemical Properties

3 - Hydroxybenzotrifluoride is a special compound. Its physical properties are special, and the outer color is often yellow to light color liquid, which has certain properties and taste. Its boiling properties are specific, and the melting properties are also fixed. The two are especially important for the determination and separation of matter.
and chemical properties. 3 - Hydroxybenzotrifluoride contains a group, has a certain activity, and can be used for multi-chemical and anti-chemical. Its specific energy can generate substitution and anti-chemical, and the group can be replaced by other groups to derive multi-derivative. And because it contains trifluoromethyl, it makes the molecule have certain qualitative and special molecular effects, which affects its anti-chemical activity and the interaction of other substances. Moreover, the physical properties of this compound make it have a place in chemical research and application.

Technical Specifications & Labeling

The process regulations and labels (product parameters) for the production of 3-Hydroxybenzotrifluoride are described in detail as follows. The process regulations, the selection of the first heavy raw materials, need to choose the highest quality and pure materials, and the ratio should be accurate, and there should be no difference in the millimeter. The temperature and pressure of the reaction also need to be strictly followed and controlled in a suitable area to ensure the smooth reaction and the purity of the product.
As for the identification (product parameters), when the characteristics of the declaration are pure in color and taste, no impurities and no impurities. Its purity must reach a very high standard, and the impurity content is minimal. All physical and chemical indicators should be detailed in the book for inspection. In this way, you can get excellent 3 - Hydroxybenzotrifluoride products, process regulations and identification (product parameters) properly, is the basis of quality.

Preparation Method

For 3-hydroxytrifluorotoluene, the preparation method is related to the raw material and production process, reaction steps and catalytic mechanism, which cannot be ignored.
To make this substance, the selection of raw materials is very important. When starting with suitable chemical substances, such as fluorine-containing, benzene ring and hydroxyl-related precursors. The production process needs to be carefully designed, and each step must be connected in an orderly manner. In the reaction step, the starting material is gradually constructed by specific reaction conditions, or through substitution, addition and other reactions.
The catalytic mechanism cannot be ignored. The selection of suitable catalysts can accelerate the reaction process, improve the yield and selectivity. Such as metal catalysts, acid-base catalysts, etc., are selected according to the reaction characteristics. Each step requires precise control of reaction parameters such as temperature, pressure and time to achieve the best reaction effect. In this way, a good method of 3-hydroxytrifluorotoluene can be obtained.

Chemical Reactions & Modifications

I am committed to the research of 3 - Hydroxybenzotrifluoride compound, and I know the key to chemical reaction and modification. In its chemical reaction, the initial ratio of raw materials, reaction temperature and time are all important factors affecting the product. In past experiments, if the ratio is slightly deviated, the purity and yield of the product will be greatly affected.
As for the modification, the purpose is to optimize its physical and chemical properties. After repeated attempts, the introduction of specific functional groups can significantly improve the stability of 3 - Hydroxybenzotrifluoride. And after modification, its solubility in specific solvents is also improved.
However, this process is not smooth sailing, and problems such as slow reaction rate and frequent side reactions are often encountered. We continue to study, adjust the reaction conditions, explore suitable catalysts, and strive to optimize the reaction to achieve better chemical properties and product quality, with the goal of expanding new applications for this compound.

Synonyms & Product Names

3 - Hydroxybenzotrifluoride, this substance is also known as hydroxytrifluorotoluene. I have been studying chemistry for many years, and I am well aware of the importance of its other names in the industry. Although this compound, or 3-hydroxy-trifluoromethylbenzene, has different names, it is actually the same thing.
In terms of trade names, the names given by different manufacturers also have their own characteristics. However, they all revolve around its chemical structure and characteristics. This substance is widely used in the chemical industry, so the clarity of its same name and trade name is of key significance in research, production and trading. Our researchers should carefully identify its various names to avoid confusion and errors in research. In this way, we can move forward steadily on the road of chemical exploration, and our understanding of 3-Hydroxybenzotrifluoride can become more profound.

Safety & Operational Standards

Safety and Handling Specifications for 3-Hydroxytrifluorotoluene
3-Hydroxytrifluorotoluene is also a chemical substance, which is quite useful in research and production. However, in order to ensure that everything goes smoothly, safety and operating standards are of paramount importance.
In the method of storage, choose a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. If this substance is co-placed with oxidants, acids, etc., it may cause chemical reactions, so it must be stored separately and must not be mixed.
As for the operation, the operator must undergo special training, be well versed in the operation process and specifications, and strictly follow the rules. The operating room should be equipped with good ventilation facilities to keep the air fresh. If necessary, the operator should wear protective clothing, protective gloves and goggles, so as to prevent the substance from touching the skin and eyes and avoid injury.
When handling, you should also be extra careful, load and unload lightly, and must not damage the container. If the container is damaged and the material leaks, disaster will occur. In the event of a leak, the first thing is to evacuate the surrounding people, isolate the leakage area, and strictly prohibit unrelated people from approaching. Emergency responders should properly collect the leaks in front of professional protective equipment and dispose of them in accordance with relevant regulations. They must not discard them at will to avoid polluting the environment.
Furthermore, in the place where this substance is used, there should be corresponding fire equipment. In case of fire danger, it can be put out in time. Operators should also be familiar with fire protection knowledge and not be chaotic in the face of danger.
In general, safety and operating standards are related to the success or failure of the use of 3-hydroxytrifluorotoluene and the safety of personnel. Only by strictly observing can all things be guaranteed, and research and production can be carried out in an orderly manner.

Application Area

"3-Hydroxytrifluorotoluene application field"
3-Hydroxytrifluorotoluene is quite useful in various application fields. In the field of medicine, it can be used as a key intermediate to help synthesize a variety of specific drugs, cure various diseases, and add a sharp tool for doctors to treat and save people. In the field of materials science, using it as a raw material can produce materials with excellent performance, excellent stability, or extraordinary corrosion resistance, which can play an important role in construction, electronics and other industries. In the field of chemical synthesis, its unique chemical properties make it the basis for the synthesis of many complex compounds, which can open up novel synthesis paths and expand the variety of chemical products. From this point of view, 3-hydroxytrifluorotoluene has great potential in many application fields, and it is an indispensable and important substance. To be further tapped by researchers, it will bring more benefits to the world.

Research & Development

I am committed to the research of 3-Hydroxybenzotrifluoride. This material has unique characteristics and has great potential in the chemical industry. I first investigated its chemical structure, explored the mystery of atomic bonding, analyzed its physical and chemical properties, and hoped to clarify its essence. Then I studied the synthesis method, tried different paths, optimized the reaction conditions, and strived to improve the yield and purity. During the experiment, every step was treated carefully, and the details were recorded for analysis. After repeated attempts and adjustments, an effective synthesis method was gradually obtained.
However, the road of research is not smooth, and problems are often encountered, such as too many reaction by-products, separation and purification are difficult. I consulted the classics, learned from the experience of predecessors, and discussed with my colleagues, and finally found a solution. Looking at the results, the synthesis technology of 3-Hydroxybenzotrifluoride is gradually maturing, and it is expected to be further promoted and applied, which may be beneficial to the development of related industries. It needs to be continuously studied in the future to improve.

Toxicity Research

Recently, I have been engaged in chemical research, focusing on the toxicity of 3-Hydroxybenzotrifluoride of this substance. It is of paramount importance to cover toxicity research, which is related to people's health and environmental safety.
I have carefully observed its chemical structure, analyzed its reaction characteristics with various substances, in order to deduce its potential toxicity. After a series of experiments, I have observed its impact on organisms, from the cellular level to small biological models.
It was found that this substance may interfere with the metabolic pathways of biological cells under specific conditions and affect the normal function of cells. However, to understand its exact degree of toxicity, mechanism of action and potential range of harm, more rigorous experiments and in-depth research are needed. Subsequent data should be widely collected and analyzed in detail, with the hope of clarifying the full picture of its toxicity and providing a solid basis for protection and application.

Future Prospects

Husband 3 - Hydroxybenzotrifluoride, a new product of chemistry. Looking at its characteristics, it is unique and has potential uses in various fields.
The future prospects are limitless. In the field of medicine, it may become the foundation of innovative drugs, adding a new way for curing diseases and treating diseases. In the field of materials, it may endow materials with strange properties, making materials stronger, tougher and have special functions.
Although its application is not widely used at present, science and technology are advancing day by day, and research is not limited. With time, it will be able to shine in industrial manufacturing, scientific research and exploration, etc., for the well-being of mankind, paving the way of light, and opening up new chapters.

Frequently Asked Questions

What are the main uses of 3-Hydroxybenzotrifluoride?

3-Hydroxytrifluorotoluene, which has a wide range of uses. In the field of medicine, it can be called a key intermediate. Due to the compounds containing trifluoromethyl, many of them have unique biological activities and pharmacological properties. With 3-hydroxytrifluorotoluene, many specific drugs can be synthesized, such as antibacterial and antiviral drugs, which are indispensable in the process of drug development.
In the field of pesticides, it also plays an important role. Pesticides made from this raw material have significant pest control effects. The presence of trifluoromethyl greatly increases the activity of pesticides, can effectively kill a variety of pests, and has good environmental compatibility, relatively small impact on the ecological environment, so it is widely used in modern agricultural pest control.
In the field of materials science, 3-hydroxytrifluorotoluene also has its place. It can be used to prepare special polymer materials, which often have excellent properties, such as good heat resistance and chemical stability. It is used in high-end fields such as aerospace, electronics and electrical appliances, and can meet the strict requirements for the special properties of materials.
In addition, in the dye industry, it can also be seen. It can be used as a raw material for synthesizing new dyes. The dyes are brightly colored, have good light resistance and washable properties, and provide high-quality dyes for textile printing and dyeing industries. In short, 3-hydroxytrifluorotoluene has shown important application value in many fields, promoting the development and progress of various related industries.

What are the physical properties of 3-Hydroxybenzotrifluoride?

3-Hydroxytrifluorotoluene is an important compound in organic chemistry. Its unique physical properties are described below.
Looking at its properties, under normal temperature and pressure, 3-hydroxytrifluorotoluene is mostly in the state of colorless to light yellow liquid, with clear texture. The appearance characterization of this compound is one of the key elements for intuitive identification.
When it comes to boiling point, the boiling point of 3-hydroxytrifluorotoluene is within a specific range. Its boiling point is restricted by factors such as intermolecular forces. The presence of trifluoromethyl in the molecule changes the molecular polarity and force, resulting in a boiling point that is different from ordinary benzene derivatives. Usually, its boiling point causes the compound to transform from liquid to gaseous state in the corresponding temperature environment. The melting point of 3-hydroxytrifluorotoluene is also an important physical property. The melting point of 3-hydroxytrifluorotoluene is specific, and this temperature is the critical value for the mutual transformation of solid and liquid states. The melting point is related to the degree of close arrangement of molecules, the type and strength of intermolecular forces. Below the melting point, the compound exists in a solid state; when it reaches the melting point and obtains enough energy, it melts into a liquid state.
The density of 3-hydroxytrifluorotoluene also has characteristics. Density, as the mass of a substance per unit volume, reflects the degree of compactness of its molecules. Due to its molecular composition and structure, the density of this compound is different from that of water and other common organic solvents. This characteristic has a significant impact on the mixing and separation of substances in chemical production and experimental operations.
In terms of solubility, 3-hydroxytrifluorotoluene has different solubility in organic solvents. It exhibits a certain solubility in some polar organic solvents, such as ethanol and acetone, because the hydroxyl group in the molecule can form hydrogen bonds with polar solvent molecules. However, in non-polar solvents, such as n-hexane, the solubility is poor, which is due to molecular polarity differences. In water, its solubility is limited due to the combined effect of strong hydrophobicity of trifluoromethyl and relatively weak hydrophilicity of hydroxyl groups.
In addition, 3-hydroxytrifluorotoluene has a certain volatility. At room temperature, although the volatility is not extremely strong, the volatilization rate increases with the increase of temperature. Volatility is not only related to the diffusion of compounds in the environment, but also has a profound impact on the safety and stability during storage and use.

What is the chemistry of 3-Hydroxybenzotrifluoride?

3-Hydroxybenzotrifluoride, Chinese name 3-hydroxytrifluorotoluene, is an important member of organic compounds. Its chemical properties are unique and interesting, let me talk about them one by one.
This compound is acidic. Because of the hydroxyl group (-OH), it can release protons (H
) under specific conditions. The oxygen atoms in the hydroxyl group are highly electronegative, which attracts strong hydrogen-oxygen bond electron clouds, causing hydrogen atoms to leave easily and show acidity. Although its acidity is weak compared to strong acids, it is very important in organic reactions and can participate in many acid-base neutralization, esterification and other reactions.
Furthermore, 3-Hydroxybenzotrifluoride has nucleophilic substitution reaction activity. The electron cloud density of the ortho and para-hydroxyl groups on the benzene ring increases due to the conjugation effect of the hydroxyl group to the electron, which makes it vulnerable to the attack of electrophilic reagents. At the same time, trifluoromethyl (-CF 🥰) is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring, making nucleophilic substitution more likely. For example, when halogenated hydrocarbons react with it, under suitable conditions, halogen atoms can be replaced to form new organic compounds.
3-Hydroxybenzotrifluoride hydroxyl groups can also participate in esterification reactions. Under acid catalysis, it interacts with carboxylic acids or acid anhydrides to form ester compounds. This reaction is commonly used in organic synthesis and can be used to prepare esters with specific structures and functions.
In addition, due to the strong electron absorption of trifluoromethyl, this compound has certain chemical stability and unique physical properties. Trifluoromethyl can enhance the lipid solubility of molecules and affect their solubility in different solvents. At the same time, it also plays a role in the physical properties of molecular boiling point and melting point.
In summary, the chemical properties of 3-Hydroxybenzotrifluoride are rich and diverse, and are widely used in organic synthesis, pharmaceutical chemistry and other fields. It is an indispensable compound in organic chemistry research and practical production.

What are 3-Hydroxybenzotrifluoride synthesis methods?

The synthesis method of 3-hydroxy trifluorotoluene has been described by many parties in the past, and each method has its own advantages.
One method is to use trifluoromethylbenzene as the starting material, first through nitrification, nitro is introduced, and then an appropriate reducing agent, such as tin-hydrochloric acid system or iron-hydrochloric acid system, is used to reduce the nitro group to amino group, and then by diazotization reaction, the hydroxyl group is substituted for the amino group to obtain 3-hydroxy trifluorotoluene. This process requires careful control of the reaction conditions, such as temperature, pH, etc., so that the reaction can be smooth and the yield is also good.
The second method can start from benzoic acid containing trifluoromethyl. First, benzoic acid is converted into acyl chloride, and then it is acylated with phenolic compounds with the help of suitable catalysts to obtain corresponding ketone products. Then by reduction means, such as catalytic hydrogenation, the carbonyl group is converted into a hydroxyl group to obtain 3-hydroxytrifluorotoluene. In this method, the preparation of acyl chloride needs to pay attention to the anhydrous environment of the reaction, and the choice of catalyst is also related to the success or failure of the reaction and the purity of the product.
Another halogenated trifluoromethylbenzene is used as a raw material. The halogen atom can be replaced by a hydroxyl group by a nucleophilic substitution reaction. This reaction often needs to be carried out in a strong alkali environment, such as sodium hydroxide or potassium hydroxide alcohol solution, and the temperature has a great influence on the reaction rate and product distribution. At the same time, it is necessary to consider the activity of halogen atoms and choose the reaction conditions reasonably to achieve the ideal synthesis effect.
This number method has its own advantages and disadvantages. In practical application, when considering the availability of raw materials, the operability of reaction conditions, the purity and yield of products and many other factors, the choice should be weighed.

What are the precautions in storage and transportation of 3-Hydroxybenzotrifluoride?

3-Hydroxytrifluorotoluene is also an organic compound. During storage and transportation, many matters need to be paid attention to.
First words storage, this substance should be stored in a cool and ventilated warehouse. Because the substance is easily dangerous when heated, it is crucial to stay away from fire and heat sources. The temperature of the warehouse should be controlled within a suitable range to avoid changes in its physical or chemical properties caused by excessive temperature. And it should be stored separately from oxidizing agents, acids, bases, etc., and must not be mixed. Due to its active chemical properties, contact with the above-mentioned substances may cause severe chemical reactions, endangering safety. At the same time, the storage area should be equipped with suitable materials to contain leaks in case of leakage, which can be properly handled in a timely manner.
As for transportation, it is necessary to ensure that the packaging is complete and the loading is safe before transportation. The material of the packaging must be able to effectively resist the corrosion and penetration of the substance to ensure that there is no leakage during transportation. During transportation, make sure that the container does not leak, collapse, fall or damage. Keep away from fire, heat sources and sun and rain when driving. Transport vehicles should follow the specified route and do not stop in densely populated areas and residential areas. Transport personnel should also be familiar with the characteristics of the substance and emergency treatment methods. In the event of an accident, effective measures can be taken quickly to reduce the harm. In this way, the safety of 3-hydroxytrifluorotoluene during storage and transportation can be ensured.