3 Fluoro 4 Cyano Benzotrifluoride
Fluoride

3-Fluoro-4-Cyano-Benzotrifluoride

Duxiu Chemical

Specifications

HS Code

594372

Chemical Formula C8H3F4N
Molecular Weight 189.11
Appearance Colorless to light yellow liquid
Boiling Point 173 - 175 °C
Melting Point N/A
Density 1.39 g/cm³
Flash Point 62 °C
Solubility Insoluble in water, soluble in organic solvents
Purity Typically high purity, e.g., 98%+
Cas Number 112172-73-9
Vapor Pressure Low at room temperature
Refractive Index 1.429 - 1.431
Chemical Formula C8H3F4N
Molecular Weight 189.11
Appearance Colorless to light yellow liquid
Boiling Point 168 - 170 °C
Density 1.386 g/cm³
Flash Point 60 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Refractive Index 1.435 - 1.437
Stability Stable under normal conditions
Packing & Storage
Packing 1 kg of 3 - Fluoro - 4 - Cyano - Benzotrifluoride packaged in a sealed, corrosion - resistant container.
Storage 3 - Fluoro - 4 - Cyano - Benzotrifluoride should be stored in a cool, dry, well - ventilated area, away from sources of heat, ignition, and direct sunlight. Keep it in a tightly - sealed container to prevent leakage and exposure to air and moisture. Store it separately from incompatible substances like oxidizing agents and bases to avoid potential reactions.
Shipping 3 - Fluoro - 4 - Cyano - Benzotrifluoride is a chemical. Shipping requires proper packaging in accordance with hazardous material regulations. It must be transported by carriers approved for such chemicals, ensuring safety during transit.
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3-Fluoro-4-Cyano-Benzotrifluoride
General Information
Historical Development
3-Fluoro-4-cyanotrifluorotoluene, the research and development process of this product can be traced back to the past. In the past, chemical sages were exploring unknown paths, and they mostly studied fluorine-containing and cyanyl compounds. At first, only a little bit of its basic physical properties were known, and it was difficult to obtain this product. However, the public persevered, and after repeated trials, they worked hard on the synthesis method. Try a variety of reaction paths first, either due to harsh conditions or low yield, but none of them were achieved. However, unremitting exploration eventually paid off, and over time, they gradually obtained the optimization method, which controlled the reaction raw materials and conditions more accurately. Therefore, the synthesis of 3-fluoro-4-cyanotrifluorotoluene has gradually matured, and since it was little known, it has now emerged in the chemical industry, laying the foundation for many subsequent studies and applications.
Product Overview
Today there is a substance called "3 - Fluoro - 4 - Cyano - Benzotrifluoride". The properties of this substance are particularly important. Its shape or colorless liquid has a specific taste. It is used in the field of chemical industry and has a wide range of uses.
Looking at its structure, it contains fluorine, cyano and trifluoromethyl groups, etc. This unique structure gives it extraordinary properties. Because of its fluorine content, good stability and low surface energy characteristics, it can be used as a key raw material in material synthesis. The existence of cyanyl groups increases its reactivity and can react with a variety of reagents to produce various fine chemicals.
This substance is also important in pharmaceutical research and development, pesticide creation, etc. In medicine, it can be used as a lead compound, and after modification, it is expected to become a good medicine for treating diseases. In pesticides, it may have high-efficiency insecticidal and bactericidal effects to ensure the health of crops. Therefore, "3 - Fluoro - 4 - Cyano - Benzotrifluoride" is an indispensable material in the chemical industry.
Physical & Chemical Properties
3-Fluoro-4-cyanotrifluorotoluene, the physical and chemical properties of this substance are related to research and application, and cannot be ignored. Its color is pure and pure, and it is liquid at room temperature, like smart water, but its properties are not as mild as water. Its boiling point is quite regular, just like following the laws of nature, and it changes rapidly at a specific temperature. Its density is also fixed, as if it carries its own weight, showing a unique state.
Furthermore, its solubility is distinct in some solvents, and in other solvents. On top of chemical activity, when encountering a specific reagent, it either reacts like a virgin or moves like a rabbit, causing a wonderful reaction. This kind of property, such as the interweaving of silk threads, paints its unique chemical picture, paving the way for scientific research and guiding the direction of exploration.
Technical Specifications & Labeling
There is a chemical product today, named "3 - Fluoro - 4 - Cyano - Benzotrifluoride". Its process specifications and identification (commodity parameters) are the key. In the process specifications, it is necessary to clarify the method of synthesis, the geometry of the materials used, the temperature and pressure of the reaction, and other conditions. It must be accurate to get good products.
As for the identification (commodity parameters), its physical properties should be recorded in detail, such as color, taste, state, geometry of melting and boiling point, and density. Chemical properties cannot be ignored, what can be applied to, and what is the stability. These two, process specifications and logos (product parameters), such as two wheels of the car and two wings of the bird, are indispensable for the production and use of "3-Fluoro-4-Cyano-Benzotrifluoride". According to this specification, the quality of this product can be guaranteed, and its circulation and application can be smooth.
Preparation Method
There are currently methods for the production of 3-fluoro-4-cyanotrifluorotoluene, which are described as follows:
In terms of raw materials, a number of specific organic reagents need to be prepared, which are the basis for the reaction. The production process is quite exquisite. The first step starts with an organic compound, and the initial reaction occurs through delicate proportions and specific environments. The reaction conditions need to be strictly set temperature and pressure to promote the fusion and transformation of raw materials.
The reaction steps are rigorous. After the initial reaction is completed, the product is finely processed and put into the subsequent reaction. This step requires precise regulation of the proportion of reactants. If there is a slight difference in the pool, the yield will be affected. And during the reaction process, there are strict requirements for the reaction time to ensure sufficient reaction.
The key to the catalytic mechanism is to choose a special catalyst, which can reduce the energy barrier of the reaction and accelerate the reaction process. The amount of catalyst needs to be calculated accurately, and too much or too little is not conducive to the reaction. With this method, it is expected to obtain high-purity 3-fluoro-4-cyanotoluene products for scientific research and industrial needs.
Chemical Reactions & Modifications
The recent research on the chemical reaction and modification of 3 - Fluoro - 4 - Cyano - Benzotrifluoride has been quite experienced. The chemical reaction of this compound was initially carried out in the usual way, but the yield was not ideal. Looking at the ancient recipe, thinking about the way of change, then changing the conditions. Temperature adjustment to adapt, the amount of variable agent is more catalytic.
It works, and the result is effective. The rate of chemical reaction increases, and the yield also rises. The reason is that the temperature-appropriate promoter, the agent and the catalyst cooperate to make the product go to the best place. And the purity of the product is increased, and the impurities are less.
As for the modification, the method of adding different groups is used. Adding a certain group to obtain a new substance. Its stability is increased, and it is better in various environments. The study of this transformation and modification can be used to create this product in the future, and to promote it to other types, opening up a new path, and hoping to contribute to karma.
Synonyms & Product Names
Today there is a thing called 3 Fluoro 4 Cyano Benzotrifluoride. This thing is used in the field of chemical industry and has a wide range of uses. There are also many synonyms, each with its own name. However, they all refer to the same substance.
In the city, this substance also has various trade names. In order to recognize its characteristics and make it easier for people to identify, merchants take different names. Although the names are different, they are actually the same thing.
The establishment of synonyms is beneficial to both academia and industry. When scholars discuss, or for the sake of research, they use one of its synonyms; when merchants trade, they also call it by different trade names due to market needs. This is all to facilitate the circulation and application of this thing.
All of this shows that the synonyms and trade names of 3 Fluoro 4 Cyano Benzotrifluoride, although different in form, are all used to identify this special chemical substance, which is indispensable in the process of chemical development.
Safety & Operational Standards
3 - Fluoro - 4 - Cyano - Benzotrifluoride Product Safety and Operation Specifications
3 - Fluoro - 4 - Cyano - Benzotrifluoride is a common chemical in chemical research. In order to ensure the safety of the experiment and the smooth operation, the following safety and operation specifications are hereby established.
#1. Storage Method
This product should be placed in a cool, dry and well-ventilated place, and must be kept away from fire and heat sources to prevent accidents. The storage area must be equipped with suitable materials to contain leaks to prevent it from being caught off guard. Do not mix with oxidants, acids, bases and other substances to avoid chemical reactions and cause major disasters.
#2. Rules of operation
Operators must undergo professional training and be familiar with the operation procedures and precautions before they can work on the job. During operation, you need to wear appropriate protective equipment, such as protective glasses, protective gloves and protective clothing, to ensure your own safety. During operation, the action should be steady and slow to avoid the chemical splashing or volatilization. If it accidentally splashes on the skin or eyes, you should immediately rinse with a lot of water and seek medical treatment in time.
#3. Emergency treatment for leakage
If a leak unfortunately occurs, first of all, the personnel in the leaked contaminated area should be quickly evacuated to a safe area, and quarantined, strictly restricting personnel from entering and leaving. Emergency responders should wear protective equipment and do not expose themselves to danger. For a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite; if the leakage is large, a dike or pit should be built for containment, and transferred to a tank car or a special collector by pump, recycled or transported to a waste treatment site for proper disposal.
#4. Disposal of waste
Disposal
Discarded 3 - Fluoro - 4 - Cyano - Benzotrifluoride must not be discarded at will. It needs to be handed over to a qualified professional treatment agency for disposal in accordance with relevant national and local regulations. The treatment process should be rigorous and standardized to prevent pollution to the environment.
Chemical research is about safety and science. Only by abiding by the above safety and operation norms can we ensure the smooth experiment, the safety of personnel and the worry-free environment.
Application Area
"The application field of 3-fluoro-4-cyanotrifluorotoluene"
Fu 3-fluoro-4-cyanotrifluorotoluene has its uses in various fields. The way of medicine can be used as the key raw material for synthesizing miraculous medicines, helping to create new agents and heal diseases. In the field of materials, it can add quality and color to high-tech materials, making the materials have specific properties, such as increasing their anti-corrosion and wear resistance. It is used in high-end equipment, which is sturdy and durable. In addition, in the electronics industry, it can help the manufacture of electronic components, making the performance of components outstanding and improving the efficacy of electronic equipment. In chemical production, it is also an important intermediate. After various reactions, a variety of chemical products are derived, and the categories are rich to meet the needs of all parties. All these show the wide application field of 3-fluoro-4-cyanotrifluorotoluene, which has made great contributions to the development of various industries in this world.
Research & Development
In recent years, in the field of chemical industry, there is a name "3 - Fluoro - 4 - Cyano - Benzotrifluoride", which has attracted the attention of our researchers. Its unique nature, in the way of various synthesis, has extraordinary potential.
We have tried our best to explore the method of its preparation. At the beginning, we tried and failed repeatedly, and all paths encountered obstacles. However, we were not discouraged, we thought about it repeatedly, and analyzed the reasons in detail. After countless tests and adjustments, we finally obtained a method, which can be more stable.
Looking at its development, the prospect is quite good. In pharmaceutical synthesis, it can be used as a key intermediate, which is expected to help the research of new drugs; in the field of materials, it may be able to add novelty. We should continue to study and explore its potential, hoping to contribute to the progress of chemical industry and promote its wide use in the world for the benefit of all people.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today there is a thing called "3-Fluoro-4-Cyano-Benzotrifluoride", and the study of its toxicity is quite important.
This thing is also used in chemical preparation, or it may be useful. However, what its nature is, it must be studied in detail. Those who study poisons in ancient times should observe its shape, observe its changes, and examine its response to things to understand the depth of its poison. The same is true of "3-Fluoro-4-Cyano-Benzotrifluoride" today.
It is necessary to explore the path of its entry into the body, either through the mouth and nose, or through the skin. After testing its entry into the body, the internal organs should be changed, and qi and blood should be changed. Observe whether it damages the liver and kidneys, disturbs its mind, and hinders its circulation of qi and blood. Detailed observation of the signs of its poison, itching, cold and heat, fainting and paralysis, cannot be ignored.
The study of toxicity is related to human life, and it must be done with a rigorous attitude. Only by careful investigation can we know the details, so as to avoid its harm and ensure the well-being of everyone.
Future Prospects
Wuguanfu 3 - Fluoro - 4 - Cyano - Benzotrifluoride is not widely used today, but its future prospects are really promising. This compound has a unique structure, and its combination of fluorine, cyano and trifluoromethyl gives many specific properties.
In the field of materials science, it is expected to develop new functional materials based on its characteristics. Or used to make electronic components with higher performance, making the equipment more delicate and efficient. In pharmaceutical chemistry, there is also potential. Due to its special structure, it may be able to develop novel drugs and make breakthroughs in the treatment of specific diseases.
Although the current research may still be in its infancy, with time and careful study, we will be able to unearth its hidden capabilities, open up new paths for future science and technology and people's livelihood, and show infinite possibilities, which is the future development.
Historical Development
Taste the chemical industry, the development is changing with each passing day, and all kinds of products have their own origins. In today's words, the birth of 3 - Fluoro - 4 - Cyano - Benzotrifluoride can also be traced.
In the past, chemical industry experts studied and searched, and first got involved in the field of fluorine-containing and cyano-based compounds. At that time, the technology was not refined, and the materials were rare. Everyone went through hardships and repeated trials. Or by chance, the embryonic form of this compound was obtained, and it was continuously improved to optimize the production process.
With the passage of time, science and technology gradually developed, and its understanding was also deepened. Chemical craftsmen strive for excellence, so that the purity of 3 - Fluoro - 4 - Cyano - Benzotrifluoride is higher and the output is more abundant. From the initial difficult creation to today's increasingly widespread application, it is a major advance in the history of chemical industry, adding to many fields and becoming an indispensable material.
Product Overview
3-Fluoro-4-cyanotrifluorotoluene is one of the chemical substances. This substance has unique properties. Its color is pure and pure, and it looks like a crystal clear body. It is active and often a key player in many reactions.
The preparation method requires a precise process, and the temperature control and speed regulation must be precise. The choice of raw materials is also essential, and the quality of the material can be used to make this good product.
It has a wide range of uses. In the field of medicine, it can be used as a key intermediate in the synthesis of special drugs to help doctors overcome difficult diseases. In the material industry, it can contribute to the research and development of new materials and endow materials with new energy.
Although it is a good thing, you must be cautious when operating it. Because of its certain danger, protection measures are essential to ensure safety, so that it can be used by human beings and develop its extraordinary value.
Physical & Chemical Properties
The physical and chemical properties of 3-fluoro-4-cyanotrifluorotoluene are crucial to research and application. Its appearance, at room temperature or in a colorless liquid state, has a special odor. Looking at its boiling point, under a specific pressure, it can reach a certain value, which is related to its gasification difficulty. The melting point is also fixed, which is related to the transformation of its solid-state liquid state.
In terms of solubility, it may perform well in organic solvents, but it may have little solubility in water. Chemically, its cyanyl and fluorine atoms give it unique reactivity. Cyanyl groups can participate in a variety of nucleophilic reactions, and fluorine atoms make molecules highly stable and electronegative. Such properties may have important uses in the fields of organic synthesis and materials science, and can be the basis for the creation of new compounds and materials.
Technical Specifications & Labeling
Nowadays, there are chemical substances 3 - Fluoro - 4 - Cyano - Benzotrifluoride, and the investigation of process specifications and identification (product parameters) is quite important. Its process specifications require detailed inspection of the selection of raw materials, and pure materials must be selected, and impurities must be slight. The reaction conditions are also critical. Temperature and pressure should be precisely controlled. For example, the reaction temperature should be stable in a certain range, with a deviation of only a millimeter, and so should the pressure to ensure a smooth reaction and a high-purity product.
As for the identification (product parameters), the purity must be clear. Its exact value reaches a very high standard, and the impurity content must also be carefully marked to show the quality. The appearance description should be accurate, and the color and state should be detailed. In addition, the storage conditions should not be ignored, and the temperature and humidity should be clearly marked to prevent their qualitative changes. In this way, a complete process specification and identification (product parameters) are essential for the research and production of this product.
Preparation Method
In order to prepare 3 - Fluoro - 4 - Cyano - Benzotrifluoride, the method of preparation is to discuss the raw materials first. When taking fluorine, cyanide and trifluoromethyl related raw materials, such as aromatic hydrocarbon halides with specific substituents, etc., as the starting quality.
As for the production process, it can be achieved through a multi-step reaction. First, the raw materials are substituted under suitable reaction conditions, such as in the presence of specific solvents and catalysts, to introduce fluorine atoms and adjust the molecular structure. This step requires precise temperature control and control, so that the reaction is sufficient and there are few side reactions.
Continued, cyanide is introduced into the molecule through the cyanide step. This process requires attention to the reaction environment to ensure that the cyanide is used safely and effectively.
At the same time, the transformation mechanism of the whole process should be considered in detail. From the chemical bond breaking and recombination of the starting material to the formation and transformation of the intermediate at each step, the purity and yield of the product are all related. Every step should be carefully operated to achieve the best preparation effect, so as to obtain a high purity of 3-Fluoro-4-Cyano-Benzotrifluoride.
Chemical Reactions & Modifications
In the chemical industry, it is the important task of chemists to focus on the change of substances, to develop new substances, and to optimize them. Today, there is 3-Fluoro-4-Cyano-Benzotrifluoride, and the chemical reaction of its synthesis needs to be studied in detail.
Look at the reaction, there may be some defects, the yield may not be very good, and side reactions may also exist. Chemists should think about changes and improve the reaction conditions, such as adjusting temperature and pressure, and selecting suitable catalysts to make the reaction more efficient.
And optimize the proportion of reactants to avoid waste, and improve the purity of the product. If improvements can be made in these areas, the production of this chemical will be able to achieve better conditions, providing better raw materials for industrial use and scientific research, and contributing greatly to the development of the chemical industry.
Synonyms & Product Names
Today there is a thing called 3 - Fluoro - 4 - Cyano - Benzotrifluoride. This substance is quite important in our chemical research. Its synonymous name may have other names, and the name of the commodity also has various names.
In the field of Guanfu chemistry, there are many things, which is a common situation. This 3 - Fluoro - 4 - Cyano - Benzotrifluoride, due to the needs of research and production, its synonymous name may be born according to different situations. As for the name of the product, the merchant may also call it another name for the convenience of promotion and the appearance of its characteristics.
When we study this object, we need to carefully investigate its synonymous name and commodity name, clarify its similarities and differences, and understand its reasons. In this way, it will help to accurately grasp its nature and use, and it will be beneficial to research and production.
Safety & Operational Standards
Safety and operation specification of 3-fluoro-4-cyanotrifluorotoluene
Fu 3-fluoro-4-cyanotrifluorotoluene is an important substance in chemical research. Its safety and operation specifications are related to the smooth research and the well-being of personnel, which cannot be ignored.
In terms of storage, it is advisable to choose a cool, dry and well-ventilated place. This substance has certain chemical activity. If the environment is not warm and humid, or its properties change, it will cause danger. Therefore, it must be avoided from open flames, hot topics, and isolated from oxidants and alkalis to prevent improper reactions.
When operating, the experimenter should be fully armed. Wear protective clothing to protect against damage to the body; wear protective gloves to avoid contact with the skin; wear goggles to protect your eyes from accidental splashing. The operation room also needs to be well ventilated and equipped with a good exhaust device to expel volatile gas in time and reduce the concentration of harmful substances in the air.
When using, the action should be slow and careful. Take accurate measurements, take according to the dose required by the experiment, do not be greedy for too much, so as not to waste and increase risk. If it is accidentally touched and splashed on the skin, rinse quickly with a lot of water, and seek medical attention if necessary; if it enters the eyes, it is necessary to rinse immediately and go to the medical office urgently.
Waste disposal should not be ignored. It should not be discarded at will. When collected in accordance with regulations, it should be handed over to a professional disposal agency for disposal in accordance with regulations, and the environment should be free of pollution.
In short, in the research and application of 3-fluoro-4-cyanotrifluorotoluene, strict adherence to safety and operating standards can ensure the safety of research and move forward steadily.
Application Area
3-Fluoro-4-cyanotrifluorotoluene, this chemical substance, has a wide range of application fields. In the field of medicine, it can be used as a key intermediate to help the research and development of new drugs, or it has a significant effect on specific diseases, such as some difficult diseases, and can open up new paths for medical treatment. In the field of materials, its characteristics may optimize material properties, such as enhancing material stability and durability, and be used to make high-end materials to make utensils more sophisticated. In terms of pesticides, it may be able to produce highly efficient and low-toxic pesticides to protect crop growth, resist pest infestation, and maintain agricultural production. With its unique chemical structure, this substance shines in many application fields, contributing to the progress of science and technology and production.
Research & Development
Today there is a thing, called 3 Fluoro 4 Cyano Benzotrifluoride, and our generation is interested in studying it. This material is very different, has a wide range of uses, and is related to various fields.
When studying this thing, we should investigate its root cause and explore its characteristics. The method of synthesis is the key to research. It is necessary to choose suitable raw materials and find subtle steps to achieve the best situation.
Looking at its development path, the prospects are promising. In industrial manufacturing, it can help new products come out; in pharmaceutical research and development, it can open the door to new drugs. However, there are also challenges ahead, such as cost control and good craftsmanship.
We should study diligently, use scientific methods to solve many problems, promote the material development, and contribute to various causes, so that their effectiveness can be fully realized and benefit the world.
Toxicity Research
Detailed observation of the physical properties of taste and smell is of great importance to people's livelihood. Today, in "3 Fluoro 4 Cyano Benzotrifluoride", its toxicity is particularly investigated. Although it is beneficial to cover the production of chemical industry, the review of toxicity should not be ignored.
Detailed examination of this substance, its molecular conformation is unique, and the combination of fluorine, cyanogen and trifluoromethyl may cause very different toxicity. In the biological system, it may disturb the normal order of cells and disrupt the track of metabolism. Observe its effect, or damage the ability of the viscera, and harm the flow of qi and blood.
However, the study of toxicity cannot be done overnight. It is necessary to apply multiple methods simultaneously, observe its effect on different organisms, study its path of entry into the body, and observe its dosage response. Only then can the true appearance of its toxicity be obtained, which is the basis for protection and application, so as to ensure the well-being of the people and promote the good use of chemical industry to avoid its harm.
Future Prospects
Wuguan 3 - Fluoro - 4 - Cyano - Benzotrifluoride is unique and has a wide range of uses. In today's world, although it has been useful, we still see it as a great expansion in the future.
This substance has stable chemical properties and can be used in many fields. Or in pharmaceutical research and development, it can add new ways to cure difficult diseases; or in material science, it can help develop materials with extraordinary properties.
In the future, when more talents join it, they can study its properties and expand its uses. Or they can emerge in the field of new energy and contribute to the transformation of energy; or they can make achievements in environmental protection technology and help make the world more peaceful. We should have great ambitions and hope to make unremitting research to make this material shine in the future, for the well-being of the world, and to achieve extraordinary things.
Frequently Asked Questions
What are the main uses of 3-Fluoro-4-Cyano-Benzotrifluoride?
3-Fluoro-4-cyano-trifluorotoluene has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate and often participates in the creation of many special drugs. Due to its special chemical structure and properties, it can endow drugs with better biological activity, selectivity and pharmacokinetic properties. For example, when developing antiviral and anti-tumor drugs, it can be used as a starting material through multiple steps of delicate chemical reactions to build complex active molecular structures, providing a powerful weapon for combating difficult diseases.
In the field of materials science, it also plays an important role. With its unique fluorine atoms and cyano groups, functional materials with excellent properties can be prepared. For example, when used to synthesize high-performance polymers, the polymer may have excellent weather resistance, chemical stability and electrical properties, and is widely used in high-end fields such as aerospace, electronics and electrical appliances. In aerospace, it can resist extreme environments and ensure stable operation of equipment; in electronic appliances, it can improve component performance and life.
In agricultural chemistry, it can be used to synthesize new pesticides. Through precise design, pesticides can be highly selective and active to target organisms, while reducing the impact on non-target organisms and the environment. This can not only effectively control pests and diseases, ensure crop yield and quality, but also conform to the current green agricultural development concept.
In addition, in the field of organic synthetic chemistry, 3-fluoro-4-cyano-trifluorotoluene serves as a unique synthetic building block, providing organic chemists with a variety of synthesis paths. Through clever design of reactions, complex organic molecular frameworks can be built, expanding the structural diversity of organic compounds, and promoting the continuous development of organic synthetic chemistry, laying a solid foundation for innovative applications in many fields.
What are the physical properties of 3-Fluoro-4-Cyano-Benzotrifluoride?
3-Fluoro-4-cyano-trifluorotoluene, this is an organic compound. Its physical properties are unique, let me tell you in detail.
Looking at its appearance, under room temperature and pressure, it is mostly a colorless to light yellow transparent liquid, clear and with a certain fluidity. Its odor, although not extremely pungent, still has a unique organic smell, which is quite distinct and can be clearly detected in specific environments.
When it comes to boiling point, it is about 190-195 ° C. At this temperature, the substance changes from liquid to gaseous state, which is of great significance in chemical operations such as distillation and separation. Its melting point is relatively low, about -20 ° C, which means that under normal low temperature environments, the substance can still maintain a liquid state and exhibit good low-temperature fluidity.
In terms of density, it is about 1.45 - 1.50 g/cm ³, which is obviously heavier than the density of water. Therefore, if this substance is mixed with water, it must sink to the bottom of the water. This property can be used for discrimination in phase separation and other processes.
Solubility is also one of its important physical properties. The substance is insoluble in water because water is a polar solvent, while the polarity of 3-fluoro-4-cyano-trifluorotoluene is relatively weak. According to the principle of "similar miscibility", the two are difficult to miscible. However, in common organic solvents, such as dichloromethane, chloroform, toluene, etc., it has good solubility and can be uniformly mixed with it to form a uniform solution. This property makes it possible to choose a suitable organic solvent as the reaction medium according to the reaction requirements in organic synthesis reactions.
In addition, the vapor pressure of 3-fluoro-4-cyano-trifluorotoluene cannot be ignored. Although the vapor pressure is not high at room temperature, with the increase of temperature, the vapor pressure increases significantly and the gas volatilization increases. This property is related to the safety of storage and use, and needs to be properly considered. In high temperature environments, it is especially necessary to be careful to prevent the latent risk caused by its volatilization.
Is 3-Fluoro-4-Cyano-Benzotrifluoride chemically stable?
The chemical stability of 3-fluoro-4-cyano-trifluorotoluene depends on many factors. In this substance, cyano (-CN), fluorine atom (-F) and trifluoromethyl (-CF) coexist. Fluorine atoms have strong electronegativity, which can change the electron cloud density distribution of benzene rings and affect their reactivity. Cyanyl groups can participate in many reactions, such as hydrolysis, addition, etc., because of their unsaturated bonds. Trifluoromethyl also has strong electronegativity and large steric resistance, which has a great impact on molecular properties.
Under normal conditions, 3-fluoro-4-cyano-trifluorotoluene is relatively stable in an inert environment, such as under the protection of dry nitrogen, at room temperature, and generally does not spontaneously undergo significant chemical reactions. When exposed to high temperatures, strong oxidizing agents or specific catalysts, its stability will be affected. For example, at high temperatures, cyano groups may undergo hydrolysis to form carboxyl (-COOH) derivatives. In the presence of strong oxidizing agents, benzene rings may be oxidized, resulting in structural changes.
If in an organic synthesis reaction system, this substance will exhibit different reactivity depending on the reaction conditions and the added reactants. In the nucleophilic substitution reaction, the fluorine atom may become the check point for the attack of the nucleophilic reagent due to the change of the electron cloud distribution of the benzene ring.
Overall, the chemical stability of 3-fluoro-4-cyano-trifluorotoluene is not absolute, and it will change with the environmental conditions and the reaction system.
What is the preparation method of 3-Fluoro-4-Cyano-Benzotrifluoride?
The preparation method of 3-fluoro-4-cyano-trifluorotoluene is not contained in the classic "Tiangong Kaiji", but it can be deduced according to the ancient synthesis idea.
First, compounds containing fluorine, cyano and trifluoromethyl are used as starting materials. The key here is to find suitable halogenated aromatics. With halogenated aromatics as the base, fluorine atoms can be introduced first. In the past, nucleophilic substitution was often used. Active halogenated aromatics and fluorinated reagents, such as potassium fluoride, were selected in specific solvents, such as dimethyl sulfoxide (DMSO), and reacted by heating. By exchanging halogen atoms and fluoride ions, fluorine-containing aromatics were obtained.
Then, a cyanyl group is introduced on the fluoroaromatic hydrocarbons. The ancient method often used halogenated aromatics to interact with cyanide reagents. Today, we can learn from it. Select suitable halogenated fluoroaromatics and cyanide reagents such as cuprous cyanide, and heat and catalyze the reaction in solvents such as pyridine, so that the cyanyl group replaces the halogen atom to obtain fluorocyanoaromatics.
Finally, trifluoromethyl is introduced. A trifluoromethylation reagent, such as sodium trifluoromethanesulfonate, can be used to react with a fluorocyanoaromatic hydrocarbon under alkali catalysis in a suitable organic solvent, such as N, N-dimethylformamide (DMF). After a series of electron transfer and nucleophilic substitution steps, the trifluoromethyl is connected to the aromatic hydrocarbon, and then 3-fluoro-4-cyano-trifluorotoluene is obtained.
In the reaction, temperature, reagent ratio, and reaction time are all critical. High or low temperature affects the reaction rate and product purity; improper reagent ratio or side reactions; insufficient reaction time makes it difficult to convert the raw materials. Therefore, fine regulation is required to obtain this compound.
What is the price range of 3-Fluoro-4-Cyano-Benzotrifluoride in the market?
3-Fluoro-4-cyano-trifluorotoluene, the price of this product in the market is difficult to determine. The change in its price is subject to many factors.
First, the situation of its production and production. If the origin is wide and the output is abundant, the market supply is abundant, its price may stabilize; on the contrary, if the output of the origin is sharply reduced, and the supply is insufficient, the price will rise.
Furthermore, the price of raw materials is also the main reason. The production of 3-fluoro-4-cyano-trifluorotoluene requires all kinds of raw materials, and the rise and fall of raw material prices directly leads to the price of its finished products. If the price of raw materials rises, in order to protect its profits, the price of this product will also rise; if the price of raw materials falls, the price may be lowered.
The demand of the market also affects its price. If many industries have strong demand for it, such as medicine, chemical industry and other fields, the demand surges, and the price will also rise accordingly; if the demand is low, merchants may reduce the price in order to promote their sales.
The advancement of technology also affects its price. If the new system method is introduced, it can reduce its manufacturing cost and increase production capacity, and the price may drop accordingly; if the technology is stagnant and the cost is difficult to reduce, the price will not drop significantly.
Trade policy, transportation costs, etc., can all affect its price. Changes in tariffs and the rise and fall of freight can be seen in its price.
To sum up, in the market, the price of 3-fluoro-4-cyano-trifluorotoluene varies from time to time and varies from situation to situation, roughly fluctuating between hundreds and thousands of yuan per kilogram. It is difficult to determine its specific price range.