3 Chloro 4 Aminobenzotrifluoride
Fluoride

3-Chloro-4-Aminobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

957779

Chemical Formula C7H5ClF3N
Molecular Weight 195.57
Appearance Colorless to light yellow liquid or solid
Boiling Point 224 - 226 °C
Melting Point 14 - 16 °C
Density 1.396 g/cm³
Solubility In Water Insoluble
Flash Point 97 °C
Vapor Pressure Low
Odor Characteristic odor
Stability Stable under normal conditions
Chemical Formula C7H5ClF3N
Molar Mass 195.57 g/mol
Appearance Colorless to light yellow liquid or solid
Boiling Point Around 220 - 225 °C
Melting Point 24 - 27 °C
Density 1.374 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point Around 98 °C
Purity Typically high - purity products around 98%+
Packing & Storage
Packing 500g of 3 - Chloro - 4 - Aminobenzotrifluoride packaged in a sealed, chemical - resistant bottle.
Storage 3 - Chloro - 4 - Aminobenzotrifluoride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and strong oxidizing agents. Store in a tightly closed container to prevent moisture absorption and evaporation. It's crucial to store it separately from incompatible substances to avoid potential chemical reactions.
Shipping 3 - Chloro - 4 - Aminobenzotrifluoride is shipped in accordance with strict chemical regulations. It's packaged securely in appropriate containers to prevent leakage during transport, ensuring safety throughout the shipping process.
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3-Chloro-4-Aminobenzotrifluoride
General Information
Historical Development
"Memorizing the Development of 3-Chloro-4-Aminotrifluorotoluene"
Fu 3-chloro-4-aminotrifluorotoluene is also a chemical substance. At the beginning, researchers investigated its properties, investigated its source, and explored the road. It was difficult to prepare. At the beginning, the preparation method was simple, the amount of production was small, and the quality was not good.
However, the years passed, and the sages were unremitting. In the conditions of the reaction, careful study; the selection of raw materials, careful weighing. Therefore, the preparation method became more and more refined, the output was improved, and the quality was greatly improved.
Since its inception, the field of application has become wider. In the field of medicine, it is the foundation of making good medicines; in the field of materials, it is the basis of innovation. Its development path, from micro to the beginning, depends on the wisdom and diligence of researchers of all dynasties, to get today's grand scene and add a wonder to the forest of chemistry.
Product Overview
3-Chloro-4-aminotrifluorotoluene is also an organic compound. Its color is pure and stable, and it has special chemical properties.
This substance is widely used in the chemical industry. In pharmaceutical synthesis, it can be a key intermediate, helping to create a variety of special drugs and cure various diseases. In material research and development, its unique structure can endow the material with excellent properties, such as weather resistance and anti-corrosion properties, making the material suitable for harsh environments.
The synthesis method requires fine control of the reaction conditions, through multi-step reactions, following precise proportions and processes, to obtain high-purity products. However, during the synthesis process, attention should also be paid to safety and environmental protection, and waste should be properly disposed of to avoid harming the environment and people.
In summary, although 3-chloro-4-aminotrifluorotoluene is small, it plays an extraordinary role in industrial development and is an indispensable and important substance in the chemical industry.
Physical & Chemical Properties
3-Chloro-4-aminotrifluorotoluene is also an organic compound. Its physical properties are solid at room temperature, white and pure in color, and have a specific melting point, which can be used to identify its purity. The determination of the melting point is a key indicator of the physical state transformation, and it is of great significance in the precise control of the production process.
In terms of its chemical properties, chlorine coexists with amino groups and trifluoromethyl groups in this compound, and the reactivity is unique. Amino groups are nucleophilic and easy to react when exposed to electrophilic reagents, and can be used to construct a variety of chemical structures. Chlorine atoms can participate in the substitution reaction, providing an opportunity for the introduction of other functional groups. The existence of trifluoromethyl groups makes the molecule highly electronegative and hydrophobic, which affects its chemical stability and reaction selectivity. In-depth study of its physicochemical properties is of great benefit to optimizing the synthesis path and expanding the application field, and can provide solid theoretical support for many industries such as chemical industry and pharmaceutical research and development.
Technical Specifications & Labeling
"On the Technical Specification and Labeling (Product Parameters) of 3-chloro-4-aminotrifluorotoluene"
The technical specification of 3-chloro-4-aminotrifluorotoluene is the key. From the beginning of preparation, all links need to follow precise methods. The selection of raw materials must be pure, and the ratio must be accurate. For example, the amount of material must be in accordance with the established number. The reaction conditions should not be ignored. The temperature and pressure are fixed or controlled within a certain range to ensure a smooth reaction.
The identification should not be ignored, and the product parameters should be detailed on the label. Such as purity geometry and impurity content should be clearly marked. In this way, the user can understand its nature, and make the best use of it when applying it, and also ensure safety. Technical specifications and labels complement each other to promote the goodness of this product.
Preparation Method
The preparation of 3-chloro-4-aminotrifluorotoluene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are often started with specific aromatic hydrocarbons, supplemented by chlorine, fluorine and other reagents. In the production process, the reaction temperature and pressure need to be precisely controlled in the initial stage, so that the aromatic hydrocarbons and chlorine reagents can be cleverly combined to obtain chlorine-containing intermediates. This step requires strict selection of catalysts to promote the efficient advancement of the reaction.
Then, the intermediate meets the fluorine reagent, and after specific reaction conditions, it is cleverly converted into a fluorochlorine-containing intermediate. The reaction steps must follow the established procedures, and the reaction time and temperature of each step must be strictly controlled. In the catalytic mechanism, the catalyst used can effectively reduce the reaction activation energy, improve the reaction rate Each step requires careful operation to ensure product purity and yield, so as to obtain high-quality 3-chloro-4-aminotrifluorotoluene.
Chemical Reactions & Modifications
There is a substance today, named 3-chloro-4-aminotrifluorotoluene. In the field of chemistry, it is the task of our chemists to explore its reaction and modification.
Looking at the reaction, many paths can be found. Or there are different products due to different reagents and conditions. For example, with a specific reagent, under a suitable temperature and pressure, the chlorine atom in the molecule may be replaced, and it will embrace the nucleophilic reagent to derive a new structure.
As for modification, there are also wonderful methods. To increase its stability, specific groups can be introduced to change its electron cloud distribution and stabilize its molecular structure. If you want better solubility, you can add hydrophilic or lipophilic groups according to the principle of "similar miscibility".
Our chemists, often in the laboratory, with a rigorous attitude, repeated experiments, to check the details of the reaction, study the modification method, hope to understand its chemical properties, pave the way for its wider application, so as to help this substance shine in the fields of chemical industry, medicine and so on.
Synonyms & Product Names
Today there is a thing called 3-chloro-4-aminotrifluorotoluene. The synonyms of this thing are also referred to by various names. Its synonyms vary depending on the physical properties and uses, and some vary according to the place of origin and production method.
or because of its chemical structure, it has the name of a specific structure association; or because of its application field, it is called differently in the pharmaceutical, chemical and other industries. As for the trade name, merchants will also give another good name in order to recognize its characteristics and attract customers.
Although the names are different, they actually refer to this 3-chloro-4-aminotrifluorotoluene. All kinds of synonyms and trade names are for the convenience of the world to call this thing in different situations, each with its own use, referring to the same entity.
Safety & Operational Standards
Specifications for the safety and operation of 3-chloro-4-aminotrifluorotoluene
Fu 3-chloro-4-aminotrifluorotoluene is also an important substance in chemical research. During the experimental operation, safety is the top priority, and norms are the guidelines.
All handling involving this substance must be done in a well-ventilated manner. This is because the substance may dissipate harmful gases. If the ventilation is not smooth, the gas will accumulate in the room, endangering the health of the operator. And the operator must wear appropriate protective equipment, such as protective clothing, protective gloves and goggles. Protective clothing can prevent it from contaminating the body surface, gloves can prevent hand contact, and goggles protect the eyes from damage.
When taking this substance, observe the rules of quantification. Take it with a precise measuring tool, do not make excess or insufficient, causing experimental deviation. And when transferring, be careful to prevent spillage. If there is a spill, clean it up immediately according to specific methods, do not leave residue, leaving safety hazards.
There are also rules for storing this substance. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Due to heat or open fire, it may cause dangerous changes. It should also be placed separately from oxidizing agents, acids and other substances to prevent their interaction and risk of accidents.
After the experiment is completed, the remaining 3-chloro-4-aminotrifluorotoluene should not be disposed of at will. When properly disposed of, or recycled, or treated harmlessly according to the specified method, in order to meet the requirements of environmental protection and safety.
In short, the whole process of handling 3-chloro-4-aminotrifluorotoluene should strictly abide by safety and operating standards, so as to ensure the smooth experiment, protect the safety of the operator, and avoid accidents.
Application Area
3-Chloro-4-aminotrifluorotoluene is also a chemical substance. Its application field is quite broad. In the field of medicine, it can be used as a key intermediate to help form a variety of specific drugs and treat various diseases in the world. In the field of pesticides, it can be used as an active ingredient to make powerful pesticides and protect crops from insect invasion. In material chemistry, it also has something to do, which can be used in material synthesis to give materials specific properties. This compound has important positions in industrial production and scientific research. Its application potential is still waiting for us to explore in depth, so as to develop its more functions, benefit the world, and contribute to the progress and development of mankind.
Research & Development
Today, there is a product called 3-chloro-4-aminotrifluorotoluene, which is of great importance in the field of chemical research. We have been dedicated to the research and development of this product for a long time.
Study the properties of this product, observe its reaction rules, and find a good method for its preparation. Many attempts in the past have been successful or failed. However, we are determined to obtain the best solution to increase its yield and improve its quality.
Its application is also wide, and it is expected to develop its talents in the fields of medicine and materials. Therefore, we are working hard to explore it in depth, understand its potential, and make it shine in various industries, promoting the progress and development of the industry. Although the road ahead is long, we must uphold the heart of research and do our best for its development.
Toxicity Research
Today, there is a substance named 3-chloro-4-aminotrifluorotoluene. The toxicity of this substance is crucial in the study of our chemicals. The toxicity of this substance is related to many aspects. We will investigate in detail to understand its effect on living beings.
After various experiments, it may be damaged to the viscera and organs of the organism. If it enters the animal body, it may disturb the operation of the liver and kidney, causing physiological disorder. Looking at its effect on cells, it seems to change the shape and function of cells, and disturb normal metabolism.
The appearance of toxicity is also related to the dose. There are few effects or little, and many are significant. We must delve into the mechanism of its toxicity, examine the relationship between dose and effect in detail, and hope that when the world uses this substance, we can clarify its advantages and disadvantages, ensure safety and avoid harm, and follow the path of chemical research and application.
Future Prospects
Fu3-chloro-4-aminotrifluorotoluene is a chemical product with unique characteristics. Looking at its future prospects, the future may change.
Its use in the field of medicine may be the basis for the development of new pharmaceuticals. With the development of medicine, the need for special ingredients is increasing, and this product may become the key to anti-disease drugs due to its characteristics. In the chemical industry, there is also potential. The rise of new materials may involve synthesis, which may help materials with new qualities, such as increased wear resistance and corrosion resistance.
However, there are also challenges. The preparation process may need to be refined to reduce costs and yield. Environmental regulations are becoming stricter, and the production process must meet the green standard. Therefore, in order to develop the future, researchers need to attack technology and find a balance, so that this product can shine in various fields, seek progress for human well-being, and become a boost for future development.
Historical Development
3-Chloro-4-aminotrifluorotoluene, the rise of this substance has gone through the years. At the beginning, chemical sages studied and searched for traces in the complex reactions. In the past, the conditions were embarrassing, the experiments were difficult and abnormal, but the predecessors made unremitting efforts.
After the technology was gradually improved, the process was improved. People repeatedly considered the reaction raw materials and steps, and strived to improve. The synthesis method has changed from crude to exquisite, and the yield has also changed from low to high.
Up to today, its preparation process has been quite mature and is widely used in many fields. Looking back on the past, it is difficult to know the difficulty of today's achievements, and it is also expected that it will be able to rise to a higher level in the future, and shine even brighter in the field of chemical industry.
Product Overview
Today there is a substance called 3-chloro-4-aminotrifluorotoluene. This substance is a key raw material for organic synthesis and is widely used in the fields of medicine, pesticides, dyes, etc.
Its shape is white to light yellow crystalline powder with specific melting point and boiling point. From the perspective of chemical structure, it contains chlorine atoms, amino groups and trifluoromethyl groups. Chlorine atoms are active and can participate in a variety of substitution reactions; amino groups can undergo acylation, alkylation and other reactions; trifluoromethyl groups give the substance unique physical and chemical properties, such as high stability and hydrophobicity.
Preparation of this substance often takes a specific chemical reaction path and is formed by multi-step reaction. Each step of the reaction requires precise control of the reaction conditions, such as temperature, pressure, catalyst, etc., to ensure the purity and yield of the product. It is widely used, and can be used as a key intermediate in the field of medicine to synthesize special drugs; in the field of pesticides, it can assist in the research of high-efficiency and low-toxicity pesticides; in the dye industry, it can endow the unique properties of dyes.
Physical & Chemical Properties
Today there is a thing called "3-chloro-4-aminotrifluorotoluene". The physical and chemical properties of the thing are worth exploring.
Looking at its physical properties, under room temperature, it is either solid or liquid, the color is colorless or slightly colored, and it needs to be carefully observed according to the experiment. Its smell should also be tested by smelling it yourself, or it has a special taste.
On its chemical properties, due to the presence of chlorine, amino groups and trifluoromethyl groups, the chemical activity is not ordinary. Chlorine atoms are active, or can participate in the substitution reaction; amino groups are basic and can combine with acids; the existence of trifluoromethyl increases its unique chemical properties. Its solubility in various solvents is also an important property, or it is easily soluble in a certain type of organic solvent and its solubility in water needs to be tested in detail. All these are important for the purpose of exploring the physical and chemical properties of this substance.
Technical Specifications & Labeling
"Technical Specifications and Labeling of 3-chloro-4-aminotrifluorotoluene (Product Parameters) "
For 3-chloro-4-aminotrifluorotoluene, its technical specifications are of paramount importance. The appearance of this product must be white to light yellow crystalline powder without visible impurities to the naked eye. The melting point should be within a specific range, about [specific melting point value] ° C, which is one of the key indicators to measure its quality. In terms of purity, it should not be less than [specific purity value]%, and the impurity content should be strictly controlled.
As for the logo, the name "3-chloro-4-aminotrifluorotoluene" should be clearly marked on the product packaging, and the chemical formula should be attached. And the production batch and production date should be indicated to facilitate traceability. In addition, warning labels are also indispensable. Because of their chemical properties or certain hazards, they should be clearly stated in accordance with relevant rules to ensure that users understand their characteristics and operate safely to achieve the standardized application of the product.
Preparation Method
The preparation method of 3-chloro-4-aminotrifluorotoluene is related to the raw material and production process, reaction steps and catalytic mechanism. The selection of raw materials is very critical. When a specific ratio of [specific raw material 1] and [specific raw material 2] are mixed, the reactivity of the two needs to meet specific conditions to ensure the smooth progress of the reaction.
In the production process, the raw materials are first placed in a special reactor, and the temperature is adjusted to [X] degrees Celsius to maintain this temperature stability to ensure a uniform reaction rate. The reaction steps are followed by initiating a preliminary reaction first, observing a slight change in the color of the system, and then slowly adding [catalyst name]. This is the key to the catalytic mechanism. The catalyst can significantly reduce the activation energy of the reaction and accelerate the reaction process. When the reaction proceeds to a predetermined time and the degree of reaction reaches the standard, a series of purification processes can be used to obtain a high-purity 3-chloro-4-aminotrifluorotoluene product. In this way, a good method for preparing this product can be obtained.
Chemical Reactions & Modifications
Today there is a chemical thing called 3-chloro-4-aminotrifluorotoluene. In the way of chemical research, its reaction and modification are very important.
Looking at its reaction, it was observed in past experiments that it combined with a certain reagent and formed a certain product according to the conventional path. However, its rate did not meet expectations, and the yield was not sufficient. This is because the reaction conditions are not precise, or the proportion of reagents is not accurate.
As for modification, you can start from the structure. In its molecular structure, a group can be modified to change its properties. Or introduce new groups to obtain specific properties. In this way, it can be used in other fields, such as material creation and pharmaceutical research and development.
To achieve this goal, when the reaction conditions are carefully studied, the temperature, pressure, and catalyst need to be carefully regulated. When modifying, it is also necessary to carefully observe molecular changes and test performance changes. This is the essence of chemical research, and I hope my colleagues will study diligently to understand the true meaning of the reaction and modification of 3-chloro-4-aminotrifluorotoluene, which will contribute to the progress of chemistry.
Synonyms & Product Names
3-Chloro-4-aminotrifluorotoluene, the synonym and trade name of this substance, is the key to chemical research. In the way of our chemical inquiry, we know many of its terms, which are of great significance.
Its synonyms are needed for accurate expression in scientific communication. In different literature, research, or other words to refer to this thing, they all refer to the same substance. For example, [list some possible synonyms, if necessary, can supplement the synonyms of relevant professionals], are its nicknames, known to the academic community.
The trade name is related to market application. Different manufacturers produce this product, or give it a unique trade name. This is to distinguish the product and occupy a place in the market competition. For example [assuming a trade name, if there is actually relevant information that can be truly listed], this trade name is the logo of the product issued by a manufacturer. Understanding its synonyms and trade names will help us navigate the world of chemical research and industrial applications without hindrance.
Safety & Operational Standards
Code for safety and operation of 3-chloro-4-aminotrifluorotoluene
Fu 3-chloro-4-aminotrifluorotoluene is an important substance in chemical research. During its experimental operation and use, safety regulations are of paramount importance.
Anyone who comes into contact with this substance must first wear suitable protective gear. Gloves must be chemically resistant to prevent skin from being invaded by contact with it. Anti-goggles are also indispensable to prevent them from splashing into the eyes and causing damage to the eyes.
The place of operation should be well ventilated. This substance may evaporate harmful gases, and good ventilation can quickly drain it, so as not to gather in the room and endanger the person. And the operating table must be kept clean and dry to prevent impurities from mixing in, affecting its properties, and preventing accidental reactions.
When taking it, the action should be slow and stable. Measure the required amount with a precise measuring tool, do not be greedy for too much, and do not take less to cause the experiment to fail to meet expectations. If it is accidentally spilled, clean it up quickly according to a specific method. Small amounts of spills can be covered with materials with good absorption, and properly disposed of after collection; large amounts of spills must be evacuated, the scene must be sealed, and handled by professionals.
The storage place should be cool, dry and protected from light. Keep away from fire and heat sources to prevent them from being decomposed by heat and causing danger. Different chemical substances must be stored in categories, and must not be mixed to prevent mutual reaction.
Furthermore, the experimenter should be familiar with emergency measures. If the skin touches it, rinse it with a large amount of water immediately, followed by a specific agent; if it enters the eye, it needs to be rinsed immediately and treated by a doctor.
In this way, strict adherence to safety and operation standards can ensure personal safety and promote the smooth experiment in the research and application of 3-chloro-4-aminotrifluorotoluene.
Application Area
3-Chloro-4-aminotrifluorotoluene is a wonder of chemistry. Its application field is worth exploring. In the field of medicine, it can be used to create special effects. With its unique chemical structure, it can fit with specific targets in organisms and help develop a cure for difficult diseases.
In the field of materials science, it is also possible. Using it as a raw material, after clever synthesis, it may be able to generate new materials with exceptional properties. For example, those with special corrosion resistance and high and low temperature resistance can be used for the manufacture of equipment in extreme environments.
Furthermore, in the fine chemical industry, this substance can be used as a key intermediate. After a series of delicate reactions, multiple fine chemicals are derived, providing indispensable raw materials for various industries and benefiting many fields.
Research & Development
In recent years, Yu devoted himself to the research of chemical substances, paying particular attention to the compound 3-chloro-4-aminotrifluorotoluene. It has great application prospects in many fields, but the synthesis process is difficult.
At the beginning, it was prepared according to the old method, and the yield was quite low and there were many impurities. Yu repeatedly deduced the reaction mechanism and adjusted various conditions. The temperature, pressure and reactant ratio were carefully considered. After months of tests, the method was finally improved. The new way optimized the reaction steps and screened the suitable catalyst, the yield was significantly improved and the impurities were effectively reduced.
However, the research did not stop there. In order to seek wider application and development of this product, I also explore its stability in different environments and its reaction characteristics with other substances. After many experiments, its properties were clarified, laying the foundation for subsequent application expansion. Looking at this achievement, although it has been achieved at the beginning, the road ahead is still long. Only by making unremitting efforts can we expect this product to shine in the chemical industry and promote the progress and development of the industry.
Toxicity Research
I have heard that there is a thing called "3-Chloro-4-Aminobenzotrifluoride", and it is an important matter to study its toxicity. This substance may be used in industry, scientific research and other fields, but its toxicity is unknown, and hidden dangers are lurking.
We study the toxicity, observe its chemistry in detail, analyze its molecular structure, and explore its response to other things. We also measure it by various methods, observe its effect in the body, and observe the physiological shadow. Or observe its damage to cells, or explore the damage to the viscera.
After many tests, if this substance is highly toxic, when it is produced and used, strict regulations should be established to ensure human safety and environmental cleanliness. If the toxicity is minimal, it should not be taken lightly, and it is still necessary to be careful to prevent the disease from not yet erupting. Make sure that the benefits of this substance are used and the harm is minimized.
Future Prospects
I have been researching "3-chloro-4-aminotrifluorotoluene" for a long time. Looking at the present, although some achievements have been made, there are still endless possibilities for future development.
This material is unique and has extraordinary potential in the fields of medicine and materials. In the future, it may be able to shine in the research and development of new drugs and find a cure for many diseases and diseases; in the process of material innovation, it is also expected to open up new horizons and greatly improve the properties of materials.
We should be diligent, refine our skills, and explore its mysteries in depth. With time, we will be able to unearth more of its hidden capabilities, use them for the world, and create brilliance, so as to achieve unfinished prospects and live up to the mission of scientific research.
Frequently Asked Questions
What are the main uses of 3-Chloro-4-Aminobenzotrifluoride?
3-Chloro-4-aminotrifluorotoluene has a wide range of uses. In the field of pharmaceutical synthesis, this compound is in a key position. It can be used as an important intermediate to prepare various specific drugs. For example, some antidepressants with unique therapeutic effects, 3-chloro-4-aminotrifluorotoluene is an indispensable raw material. Through a series of delicate chemical reactions, it can construct a molecular structure with specific pharmacological activities, which in turn regulates the function of the human nervous system and relieves depressive symptoms.
In the field of pesticide creation, it also has significant functions. It can be converted through specific chemicals to produce high-efficiency and low-toxicity insecticides. Such pesticides can precisely act on the specific physiological targets of pests, interfering with their normal physiological metabolism, such as destroying the nervous system conduction of pests or inhibiting key enzymes related to their growth and development, thus effectively killing pests, and have little impact on the environment and non-target organisms, meeting the strict requirements of modern green agriculture for pesticides.
Furthermore, in the field of materials science, 3-chloro-4-aminotrifluorotoluene can participate in the synthesis of special polymer materials. After polymerization and other processes, it is integrated into the polymer skeleton to give the material excellent chemical resistance, heat resistance and other characteristics. These special polymer materials can be used in high-end fields such as aerospace and electronics to meet their extremely high demand for special properties of materials.
What are the physical properties of 3-Chloro-4-Aminobenzotrifluoride?
3-Chloro-4-aminotrifluorotoluene is one of the organic compounds. Its physical properties are worthy of detailed observation.
Looking at its appearance, it often shows a crystalline powder like white to light brown, which is easy to identify. Under the eye, the state of its fine particles can be observed.
When it comes to the melting point, it is about 39-43 ° C. The melting point is the critical temperature at which the substance changes from solid to liquid. In this temperature range, the intermolecular force of the compound can just cause the solid structure to disintegrate, and then it becomes liquid. The characteristics of this melting point are an important reference for the identification, separation and purification of the substance.
The boiling point is about 254 ° C. The boiling point is the temperature at which the saturated vapor pressure of the liquid is equal to the external pressure. When this boiling point is reached, the molecule of 3-chloro-4-aminotrifluorotoluene is energized enough to overcome the constraints of the liquid phase and escape into the gas phase. This boiling point value is of great significance in the operation of distillation in chemical production.
Furthermore, its solubility is also a key physical property. In organic solvents such as ethanol, ether, and acetone, 3-chloro-4-aminotrifluorotoluene has good solubility. This is because the molecular structure of these organic solvents has a chemical affinity with the compound, which can make the molecules uniformly disperse. However, the solubility in water is not good, and the difference between the polarity of water and the structure of the compound makes it difficult for the two to blend. The characteristics of this solubility affect its reaction and application scenarios in different media.
In terms of density, it is about 1.42g/cm ³. The density represents the mass of the substance per unit volume. This value reflects the compactness of its molecular accumulation. It is an indispensable parameter in practical applications such as stoichiometry involving mass and volume conversion and material transportation and storage.
In addition, its stability also belongs to the category of physical properties. Under normal environmental conditions, 3-chloro-4-aminotrifluorotoluene has certain stability, but in case of high temperature, open flame or strong oxidant, the stability is damaged and it is easy to cause chemical reactions. This stability feature requires careful consideration and precautions during its storage and use.
What are 3-Chloro-4-Aminobenzotrifluoride synthesis methods?
The synthesis method of 3-chloro-4-aminotrifluorotoluene has been around for a long time, and with the passage of time, it has become more and more complicated and delicate. The following are the common methods.
First, 3-chloro-4-nitrotrifluorotoluene is used as the starting material, and the target product is obtained by reduction method. In the past, iron powder and hydrochloric acid systems were mostly used. The reaction was as follows: 3-chloro-4-nitrotrifluorotoluene was placed in a reactor with iron powder and hydrochloric acid, and slowly heated. During the process, the iron powder was eroded by hydrochloric acid, and the released hydrogen atoms gradually reduced the nitro group to an amino group. Although this process is relatively simple to operate, the amount of iron powder is quite large, and after the reaction is completed, the treatment of waste iron filings is complicated and easy to cause environmental pollution. Later, the catalytic hydrogenation method is replaced, and palladium carbon, platinum carbon, etc. are often used as catalysts to reduce in hydrogen atmosphere. This method has relatively mild reaction conditions, high product purity, and no fear of iron sludge, and has gradually become the mainstream. For example, under appropriate temperature and pressure, the ethanol solution of 3-chloro-4-nitrotrifluorotoluene and palladium carbon catalyst are co-placed in an autoclave, and hydrogen is introduced. After several times of reaction, high-purity 3-chloro-4-aminotrifluorotoluene can be obtained.
Second, starting from fluoroaromatic hydrocarbons, it is synthesized through a series of steps such as halogenation, nitration, and reduction. First, fluoroaromatic hydrocarbons are halogenated under appropriate conditions, and chlorine atoms are introduced. For example, chlorine and ferric chloride are used as halogenation systems, so that aromatic hydrocarbons and chlorine gas are substituted under the catalysis of ferric chloride, and chlorine atoms are introduced at specific positions in the benzene ring. Then nitrification is carried out, and the nitro group is treated with mixed acid (a mixture of concentrated sulfuric acid and concentrated nitric acid), so that the nitro group is precisely positioned and in a suitable position with the chlorine atom. Finally, as mentioned earlier, the nitro group is converted into an amino group by catalytic hydrogenation or chemical reduction, thereby obtaining 3-chlor The length of this route lies in the easy availability of raw materials. Although there are many steps, the reaction of each step is relatively mature, and the reaction conditions can be flexibly adjusted according to actual needs to obtain the best yield and purity.
Third, there are also other compounds containing nitrogen, chlorine, and fluorine synthesized by coupling reactions. For example, a specific chlorofluorine-containing halogenated aromatic hydrocarbon and an amino-containing compound are coupled under palladium catalysis. This reaction requires fine regulation of the reaction conditions and requires a high catalyst. However, it has the advantages of high atomic economy and few side reactions. At the moment of pursuing green chemical synthesis, it has great research and application potential.
What are the precautions in storage and transportation of 3-Chloro-4-Aminobenzotrifluoride?
For 3-chloro-4-aminotrifluorotoluene, many precautions need to be paid attention to during storage and transportation.
This substance has certain chemical activity, and when stored, the first environment is dry. Because moisture can easily induce its chemical reaction and damage its quality. The warehouse should be selected in a cool place, and strict protection against rainwater leakage.
Temperature is also critical. It should be stored in a cool place to avoid heat. High temperature may cause it to decompose, evaporate, and even pose a risk of safety. Therefore, the warehouse needs to be equipped with cooling facilities, such as air conditioners, ventilation devices, etc.
Furthermore, the substance must be stored in isolation from oxidants, acids, alkalis, etc. These substances meet with it, or react violently, causing the disaster of ignition.
When transporting, the packaging must be sturdy. Use suitable packaging materials, such as special iron drums, plastic drums, etc., to ensure that it will not be damaged or leaked during transportation.
Transportation vehicles should also be clean, dry, and prohibited from mixing with the above-mentioned objects. During driving, drivers should drive slowly and steadily to avoid bumps and vibrations and prevent damage to the packaging.
When loading and unloading, operators should be cautious and wear protective equipment, such as gloves, goggles, etc. It is strictly forbidden to drop or press lightly to avoid packaging cracking, material leakage, and endangering the environment and personal safety.
In short, the storage and transportation of 3-chloro-4-aminotrifluorotoluene is related to safety and quality, and all aspects must be strictly adhered to, and must not be slack and negligent.
What is the market outlook for 3-Chloro-4-Aminobenzotrifluoride?
3-Chloro-4-aminotrifluorotoluene is also an important substance in organic synthesis. It is widely used in the fields of medicine, pesticides, and dyes.
Looking at its pharmaceutical field, it is often the key intermediate for the creation of new drugs. In today's world, there is a growing demand for high-efficiency and special drugs. With its unique chemical structure, this compound can introduce different functional groups through various reaction paths to form drug molecules with specific pharmacological activities. For example, the development of antidepressant and anti-infective drugs relies on this intermediate, and its market prospect is quite broad.
In the field of pesticides, it is an important raw material for the preparation of high-efficiency and low-toxicity pesticides. At present, agriculture pursues green and sustainable development, and high-efficiency and low-toxicity pesticides are the general trend. Pesticides made of 3-chloro-4-aminotrifluorotoluene can accurately act on pests, are environmentally friendly, and have little residue. Therefore, in the pesticide market, demand is also on the rise.
In the dye industry, due to its stable chemical properties, dyes can be endowed with excellent light resistance and weather resistance. With the development of textile, printing and dyeing and other industries, the demand for high-quality dyes is increasing. Dyes made of this material can meet the market's requirements for lasting and bright colors, and market share is expected to expand.
However, its market also has challenges. The synthesis process is complex and the cost is high, which limits its large-scale application. And the environmental protection supervision is becoming stricter, and the production process needs to meet strict environmental protection standards, which increases the cost and technical difficulty of enterprises. However, with the progress of science and technology, process optimization, and cost reduction; if enterprises can overcome environmental protection problems, the market prospect of this compound remains bright, and its application in various fields may be more extensive and in-depth.