3-Bromobenzotrifluoride

Duxiu Chemical

Specifications

HS Code	391796
Chemical Formula	C7H4BrF3
Molar Mass	225.006 g/mol
Appearance	Colorless to light yellow liquid
Density	1.665 g/mL at 25 °C
Boiling Point	189 - 191 °C
Melting Point	−37 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ether, benzene
Flash Point	71 °C
Vapor Pressure	0.47 mmHg at 25 °C
Refractive Index	1.4770 - 1.4790 at 20 °C

Packing & Storage

Packing	500 - gram bottle packaging for 3 - Bromobenzotrifluoride chemical.
Storage	3 - Bromobenzotrifluoride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials like stainless steel or certain plastics. This helps prevent leakage and degradation, ensuring its stability during storage.
Shipping	3 - Bromobenzotrifluoride is shipped in accordance with strict chemical transport regulations. It's packaged in suitable containers to prevent leakage. Shipment may be by road, rail, or sea, with proper hazard labeling and safety precautions.

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General Information

Historical Development

The industry of chemical industry is changing with each passing day, and the research of substances is introducing new ones. Today there are 3-Bromobenzotrifluoride of this thing, and it is gradually becoming more and more important in various fields of chemical industry.
Looking back to the past, at the beginning, everyone did not know about this thing, but after the unremitting study of various sages, its nature gradually became clear. At the beginning, only a few experiments saw its shadow, and the operators were careful and cautious to explore its nature.
Years have passed, technology has advanced, the preparation method has become better, and the yield has also increased. Since the small laboratory, as for the wide range of workshops, its application has gradually widened. Or used in the production of materials, or devoted to the research of medicine, to help many fields move forward.
Looking at its development path, from little-known to indispensable, it is a wonderful chapter in the history of chemical industry, and it is also expected that more wonderful achievements will be exhibited in the future to help the chemical industry climb to new heights.

Product Overview

3-Bromotrifluorotoluene is also an organic compound. It is a colorless to light yellow liquid with a special odor. It has a low boiling point and is volatile at room temperature.
This compound is widely used in the field of organic synthesis. It can be used as an intermediate to make various products such as medicine, pesticides and dyes. Because it contains bromine and trifluoromethyl, it has a unique chemical activity. Bromine atoms can participate in nucleophilic substitution reactions, allowing molecules to combine with other reagents to form new compounds. Trifluoromethyl gives it special physical and chemical properties, such as enhancing the lipid solubility and stability of compounds.
During synthesis, it is often necessary to control reaction conditions, such as temperature, catalyst and reactant ratio, in order to obtain high-purity products. There are various preparation methods, which can be prepared by a series of reactions such as halogenation and fluorination of the corresponding raw materials. However, safety should also be paid attention to in the synthesis, because it has certain toxicity and volatility, and the operation should be carried out in a well-ventilated place and follow relevant safety regulations.

Physical & Chemical Properties

3-Bromobenzotrifluoride is an organic compound, and its physical and chemical properties are particularly important. Looking at its physical properties, it is a colorless to light yellow liquid at room temperature, with a special odor. Its boiling point is about 187-189 ° C. At this temperature, the substance changes from liquid to gaseous state, which needs to be considered in separation, purification and other operations. The melting point is about -27 ° C. Below this temperature, it solidifies into a solid state.
When it comes to chemical properties, the bromine atom in its molecule is quite active and easily participates in the substitution reaction. The electron cloud distribution of the benzene ring allows it to undergo electrophilic substitution and introduce other functional groups. The presence of trifluoromethyl gives it unique chemical stability and hydrophobicity. Due to the presence of fluorine atoms, it reacts with many reagents in a particularly regular manner, and is widely used in the field of organic synthesis. It can prepare a variety of fluorine-containing compounds and provide important raw materials for medicinal chemistry and materials science.

Technical Specifications & Labeling

Today there is a thing called 3-Bromobenzotrifluoride. The technical specifications and identification (commodity parameters) of its production are the key.
To make this thing, you need to follow the precise method. The choice of raw materials, when pure, the proportion must be appropriate. When reacting, the temperature and pressure must be controlled in a fixed area, and there should be no slight difference. The reaction device should also be clean and suitable, so as not to mix in and damage its quality.
In terms of identification, list its physical and chemical properties in detail. Such as color, taste, and state, it must be clear and definite. Parameters such as melting boiling point and density also need to be accurately remembered. The purity geometry and the presence of impurities should be marked in a clear place so that the viewer can clearly understand their quality. Only in this way can the product of 3-Bromobenzotrifluoride be suitable for use, up to the standard, and used by the world.

Preparation Method

The method of making 3-Bromobenzotrifluoride is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials are selected to contain bromine and trifluoromethyl related substances, and are prepared by multi-step reaction.
First take a suitable bromine-containing aromatic hydrocarbon and prepare it with a trifluoromethyl-containing reagent. In the reactor, adjust the temperature to be appropriate, and add a catalyst to promote the reaction. The catalyst can reduce the reaction energy barrier and increase the reaction rate.
The reaction step is initially nucleophilic substitution or addition, so that bromine and trifluoromethyl groups are connected to aromatic hydrocarbons. After separation and purification, impurities are removed to obtain pure products.
In the production process, temperature control, pressure control and time control are essential. Precise control can increase the yield and purity of the product. And in each step of the reaction, the reaction process is carefully observed, and the conditions are adjusted in time to ensure the smooth reaction. In this way, high-quality 3-Bromobenzotrifluoride products can be obtained.

Chemical Reactions & Modifications

In recent years, 3 - Bromobenzotrifluoride this substance, its chemical reaction and modification are quite critical. In the process of chemical reaction, benzo-trifluoride is often used as the basis, and it is obtained by bromination. However, the initial method, the yield is not high, and the secondary reaction occurs frequently.
We have tried our best to improve the method. With a new catalyst, the temperature and pressure of the reaction are regulated to make the reaction more smooth. After this change, the yield can be significantly increased, and the secondary reaction can also be greatly reduced.
As for the modification, consider the introduction of other groups to change its materialization. After various attempts, it was found that the introduction of specific functional groups can make it more soluble in specific solvents and enhance its thermal stability.
From this point of view, through the study of chemical improvement and modification, the quality and properties of the 3-Bromobenzotrifluoride products have been optimized, paving the way for its wide use in various fields.

Synonyms & Product Names

Today there is a thing called 3-Bromobenzotrifluoride. It has many other names in the city. However, in its essence, they all refer to the same thing. This thing has a wide range of uses in the field of chemical industry, either as a raw material or as an auxiliary agent, and can play its role.
The ancients said: Those who are famous are the real guests. Although their names are different, the entities they refer to are not the same. Merchants in the city, or commensurate with common names, so that everyone can identify them; scholars, but mostly use academic names to show their rigor.
This 3-Bromobenzotrifluoride, in different classics and exchanges in the industry, has different aliases. However, we should discern it, and not mistake it for the difference in name. We must explore its nature with a scientific attitude to clarify its use, so as to live up to the value of this thing.

Safety & Operational Standards

3 - Bromobenzotrifluoride Safety and Practice
#1. Introduction
There are chemical substances today, named 3 - Bromobenzotrifluoride. In our chemical research, its safety and operation standards are very important and cannot be ignored.
#2. Safety Matters
1. ** Toxicity Prevention **: This substance is toxic, touches the human body, or causes discomfort. If it touches the skin, rinse with plenty of water quickly, and seek medical treatment. If it accidentally enters the eyes, it is necessary to immediately buffer with water, do not rub it, and then seek medical attention.
2. ** Environmental Considerations **: In the place of experiment or production, it is necessary to ensure good ventilation to prevent the accumulation of volatile gas. If this gas is pervasive, it may be harmful to everyone. And when disposing of its waste, it should not be discarded at will in accordance with relevant regulations to avoid polluting the environment.
#3. Operating specifications
1. ** Method of access **: When taking 3-Bromobenzotrifluoride, use clean and dry utensils. And the operation should be slow to avoid its splashing. If the dosage needs to be accurate, use a suitable measuring tool to measure to ensure that it is correct.
2. ** Reaction operation **: When used in chemical reactions, the reaction conditions must be carefully observed. Temperature, pressure and other factors are all related to the success or failure of the reaction and safety. When reacting, pay close attention to the reaction process. If there is any abnormality, take measures quickly.
3. ** Storage method **: It should be stored in a cool, dry and ventilated place, away from fire and heat sources. And it needs to be separated from oxidants, alkalis and other substances to prevent dangerous reactions.
#4. Conclusion
3 - Although Bromobenzotrifluoride is an important substance for chemical research, its safety and operation standards need to be kept in mind at all times. Only by following this can we ensure the smooth progress of research and protect ourselves and the environment.

Application Area

Today there is a thing called 3-Bromobenzotrifluoride. This thing has its own uniqueness in various application fields. In the field of medicine, it is often the key raw material for synthesizing good medicines. With its characteristics, it can participate in subtle reactions, make medicines that can cure diseases, or treat diseases, or relieve mild diseases, and benefit patients.
In the world of materials, it also has extraordinary power. With its chemical properties, it can help develop new materials, or increase their strength, or add their toughness, or give them special properties, so that the material is suitable for various scenarios, such as the needs of construction and equipment.
In agriculture, it can also play a role. Or can make insect and pest control agents, to ensure the safety of crops, the prosperity of agricultural protection, increase the production of acres, to help people's livelihood needs.
This 3-Bromobenzotrifluoride, in medicine, materials, agriculture and other application fields, are not to be underestimated, for the development of various undertakings, has a pivotal significance.

Research & Development

Today there is a chemical thing, named 3 - Bromobenzotrifluoride. Our generation has been working hard to study this thing. At the beginning, we observed its properties, analyzed its structure, and understood its chemical properties. We also explored the method of synthesis, tried various paths, and hoped to obtain an efficient way. In terms of reaction conditions, we also studied in detail, and the temperature, pressure, and catalyst were all finely regulated.
After long-term research, it has been slightly effective. The method of synthesis has gradually been optimized, and the yield has also increased. However, the way of science has no end. We still need to work hard to move forward, and explore in depth the purity of products and the expansion of production scale. With unremitting efforts, this product can be used in various fields of industry and scientific research, contributing to the progress of chemistry and promoting its sustainable development.

Toxicity Research

Yu Taste is dedicated to the study of poisons, and recently focused on 3 - Bromobenzotrifluoride this substance. The investigation of its toxicity is of great significance.
Looking at its physical properties, 3 - Bromobenzotrifluoride has a clear color and a different taste, and exists in a specific environment. However, in order to understand its toxicity, multiple methods need to be applied. Yu used animals as a test to observe their reactions after ingesting this agent. At first, the behavior of the tested animals was slightly different, and then gradually became sluggish, or had a convulsive state.
Analyzing its changes in the environment, it can enter the water and soil, causing disturbance to the surrounding ecology. The growth of plants and the reproduction of insects have changed because of it. From this point of view, the toxicity of 3 - Bromobenzotrifluoride cannot be underestimated, and it is necessary to study its harm in depth in order to find a solution to protect the safety of all beings and the peace of the environment.

Future Prospects

In the field of materials science, or it can assist in the research of new materials, with special properties, such as better resistance and weather resistance, it can be used in aviation, construction, etc. In the field of research and development, or in the new system to provide contracts, it is expected to obtain special effects and solve the suffering of many patients.
In addition, in the field of synthesis, it may be an important raw material or material, which can help in the synthesis of general and useful materials. In the future, the progress of science and technology, the depth of research, 3 - Bromobenzotrifluoride will be greatly expanded, and its extraordinary value will be developed, which will bring us a lot of well-being in our lives.

Frequently Asked Questions

What is the chemistry of 3-Bromobenzotrifluoride?

3-Bromotrifluorotoluene, an organic compound, is mostly colorless to light yellow liquid. It has a special odor and is insoluble in water, but it can be miscible with common organic solvents such as ethanol and ether.
This substance has active chemical properties and is widely used in the field of organic synthesis. Due to the high activity of bromine atoms on the benzene ring, a variety of substitution reactions can occur. For example, in nucleophilic substitution reactions, bromine atoms are easily replaced by nucleophiles such as hydroxyl and amino groups, thereby preparing various compounds containing different functional groups. In metal-catalyzed coupling reactions, such as Suzuki coupling reactions with boric acid compounds catalyzed by palladium, new carbon-carbon bonds can be formed, laying the foundation for the synthesis of complex organic molecules.
In addition, due to the strong electron-withdrawing effect of trifluoromethyl, the electron cloud density of benzene ring decreases, making its electrophilic substitution activity different from that of ordinary benzene series, and the reaction conditions and check point selectivity are different. This property makes 3-bromotrifluorotoluene play an important role in the fields of medicinal chemistry and materials science, and can be used to develop new drugs and functional materials.

What are the main uses of 3-Bromobenzotrifluoride?

3-Bromotrifluorotoluene is an essential material for organic synthesis. It has a wide range of uses and is often a key intermediate in the creation of new drugs in the field of medicinal chemistry. It can participate in the construction of complex drug molecular structures through specific reaction pathways, laying the foundation for the development of drugs for the treatment of various diseases.
In the field of pesticide chemistry, it also has important functions. Using it as a starting material, it can derive many high-efficiency and low-toxicity pesticide varieties, which have outstanding control effects on crop diseases and pests, and help increase agricultural yield.
In the field of materials science, 3-bromotrifluorotoluene can be used to prepare polymer materials with special properties. After ingenious polymerization, the resulting materials may have excellent heat resistance, chemical corrosion resistance and other characteristics, and have broad application prospects in high-end fields such as aerospace, electronics and electrical appliances.
Furthermore, in the field of dye chemistry, it also plays an important role. With the help of a series of chemical reactions, it can be converted into bright-colored and good-fastness dyes to meet the needs of high-quality dyes in textile, printing and dyeing industries.
To sum up, 3-bromotrifluorotoluene plays an indispensable role in many fields such as medicine, pesticides, materials, and dyes, promoting technological innovation and development in various industries.

What is 3-Bromobenzotrifluoride synthesis method?

The synthesis of 3-bromotrifluorotoluene is an important topic in the field of organic synthesis. There are various synthesis paths, and there are several common ones.
First, trifluorotoluene is used as the starting material, and the target product can be obtained by bromination reaction. In this process, brominating agents such as bromine ($Br_2 $) are commonly used, and suitable catalysts need to be selected. If iron powder ($Fe $) or iron tribromide ($FeBr_3 $) is used as the catalyst, trifluorotoluene and bromine undergo electrophilic substitution under heating conditions. Trifluoromethyl is used as the meta-site group, and the bromine atom is mainly replaced in the benzene ring interposition, thereby generating 3-bromotrifluorotoluene. The reaction mechanism is as follows: the bromine molecule is polarized under the action of the catalyst, generating an active electrophilic reagent, attacking the position with high electron cloud density of the benzene ring, and going through the intermediate step to finally form the product.
Second, it can be achieved by introducing trifluoromethyl from bromine-containing aromatic compounds. For example, first react with a suitable bromoaromatic hydrocarbon with a trifluoromethylation reagent. Trifluoromethylation reagents such as trifluoromethyl magnesium halide ($CF_3MgX $, $X $is halogen) are commonly used. This reaction is usually carried out in a specific solvent under strict conditions of anhydrous and oxygen-free, such as tetrahydrofuran (THF). The reaction goes through complex steps such as nucleophilic substitution to achieve the introduction of trifluoromethyl, and then 3-bromotrifluorotoluene is synthesized.
Or, through other complex multi-step reactions, the benzene ring skeleton is first constructed, and then bromine atoms and trifluoromethyl are introduced in sequence. Although this method is cumbersome, it is also feasible in some specific cases due to the availability of starting materials or the need for reaction selectivity. In short, there are many methods for synthesizing 3-bromotrifluorotoluene, and the optimal path needs to be selected according to the actual situation, such as raw material cost, reaction conditions, product purity requirements, etc.

What 3-Bromobenzotrifluoride need to pay attention to when storing and transporting

3-Bromotrifluorotoluene is an organic compound. When storing and transporting it, you must pay attention to many matters.
First word storage. This substance should be stored in a cool and ventilated warehouse. Because of the cool and ventilated place, it can be avoided due to excessive temperature or poor air. If the temperature is too high, it may cause its volatilization to intensify, or even cause chemical reactions, endangering safety. The temperature of the warehouse should be controlled within a specific range to avoid accidents. And it must be kept away from fire and heat sources, both of which are potential dangerous factors, which may cause burns, explosions and other disasters. Because of its flammability, fire and explosion prevention is of paramount importance.
In addition, it should be stored separately from oxidants and alkalis, and must not be mixed. Both oxidants and alkalis are prone to chemical reactions with 3-bromotrifluorotoluene, or cause material deterioration, or dangerous products. And the storage area should be equipped with suitable materials to contain leaks in case of leakage, which can be disposed of in time to prevent their spread and cause greater harm.
As for transportation. Before transportation, make sure that the container is well sealed and there is no risk of leakage. If the container is not well sealed, there may be leaks during transportation, which will not only damage the goods, but also pollute the environment and endanger the surroundings. When transporting, transportation enterprises and personnel with corresponding qualifications should be selected, and they should be familiar with the characteristics and transportation requirements of such chemicals. Transportation vehicles must also be equipped with necessary emergency treatment equipment and protective equipment for emergencies. During driving, it is advisable to travel steadily to avoid bumps and violent vibrations to avoid damage to containers due to collisions. And transportation routes should avoid sensitive areas such as densely populated areas and water sources, so as to reduce the harm in case of accidents.

3-Bromobenzotrifluoride impact on the environment and human health

3-Bromotrifluorotoluene is an organic compound commonly used in the chemical industry. Its impact on the environment and human health cannot be underestimated.
At the environmental end, it has considerable stability, is not easy to degrade in the natural environment, and can be retained for a long time. If released into the atmosphere, it may participate in photochemical reactions and generate harmful secondary pollutants, such as ozone, which have adverse effects on atmospheric quality and destroy the chemical balance of the atmosphere. If it flows into the water body, it may affect the survival of aquatic organisms. Because of its lipid solubility, it is easy to accumulate in aquatic organisms and pass through the food chain, causing the accumulation of toxins in higher organisms and destroying the balance of aquatic ecosystems. And because of its chemical properties, it may interfere with the chemical process of the water body and affect the water quality. If it enters the soil, it may affect the activity and community structure of soil microorganisms, hinder the decomposition of organic matter and nutrient circulation in the soil, change the physical and chemical properties of the soil, and then affect plant growth.
As for human health, it can invade the human body through respiratory tract, skin contact and accidental ingestion. Inhalation through the respiratory tract can irritate the mucosa of the respiratory tract, causing symptoms such as cough, asthma, and breathing difficulties. Long-term exposure to this may damage lung function and increase the risk of respiratory diseases. If skin contact, it may cause contact dermatitis, causing skin redness, swelling, itching, pain and other discomfort. Accidental ingestion can irritate the gastrointestinal tract, causing nausea, vomiting, abdominal pain, diarrhea and other digestive system symptoms. In more serious cases, it may have potential carcinogenicity and reproductive toxicity. Long-term exposure may interfere with the human endocrine system, affect hormone balance, and have adverse effects on reproductive function, such as affecting fertility and abnormal fetal development. It may also damage the human nervous system and immune system, weaken the human body's ability to resist diseases, affect the normal function of the nervous system, and cause symptoms such as headache, dizziness, fatigue, and memory loss.
Therefore, during the production, use and disposal of 3-bromotrifluorotoluene, effective protective measures should be taken in strict accordance with relevant safety regulations and environmental protection standards to reduce its harm to the environment and human health.