3 Bromo 5 Nitrobenzotrifluoride
Fluoride

3-Bromo-5-Nitrobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

150802

Chemical Formula C7H3BrF3NO2
Molecular Weight 270.003
Appearance Yellow to brown solid
Melting Point 34 - 38 °C
Boiling Point 237 - 238 °C
Density 1.807 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
Flash Point 100.5 °C
Purity Typically high - purity products around 97%+
Cas Number 393-15-7
Chemical Formula C7H3BrF3NO2
Molecular Weight 270.003
Appearance Yellow to brown solid or liquid
Boiling Point 233 - 234 °C
Melting Point 31 - 35 °C
Density 1.842 g/cm³
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Flash Point 100 °C
Vapor Pressure Low at room temperature
Stability Stable under normal conditions, but reacts with strong oxidizing agents

As an accredited 3-Bromo-5-Nitrobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - Bromo - 5 - Nitrobenzotrifluoride packaged in a sealed chemical - grade bottle.
Storage Store 3 - Bromo - 5 - Nitrobenzotrifluoride in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Isolate it from incompatible substances like oxidizing agents and reducing agents to prevent potential reactions.
Shipping 3 - Bromo - 5 - Nitrobenzotrifluoride is shipped in well - sealed, corrosion - resistant containers. Compliance with hazardous chemical shipping regulations ensures safe transportation, minimizing risks during transit.
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3-Bromo-5-Nitrobenzotrifluoride
General Information
Historical Development
The historical evolution of 3-bromo-5-nitrotrifluorotoluene is worth exploring. In the past, chemists worked diligently on the way of organic synthesis. At first, the knowledge of such compounds containing halogen and nitro groups was still shallow. However, with the passage of time, the synthesis technology has become more and more exquisite. Researchers have gained insight into its structural characteristics and studied the reaction mechanism.
In the past, in the laboratory, Zhu Gong repeatedly tried and combined different raw materials and conditions. After countless setbacks, they finally got the method of preparing this compound. From the crude method at the beginning to the increasingly perfect process, every step is soaked with the wisdom and sweat of predecessors. Due to this, 3-bromo-5-nitrotrifluorotoluene has gradually emerged in the field of organic synthesis, laying the foundation for many subsequent studies and applications.
Product Overview
3-Bromo-5-nitrotrifluorotoluene is also an organic compound. Its color may be slightly yellow, and it is a liquid with a special odor. This compound has a wide range of uses in the field of organic synthesis.
In its structure, bromine atoms, nitro groups and trifluoromethyl groups coexist, and this unique structure endows it with specific chemical properties. Bromine atoms are highly active and can participate in a variety of nucleophilic substitution reactions, which is a key check point for the introduction of other functional groups. Nitro groups have strong electron absorption and can affect the distribution of electron clouds in molecules, which in turn affects the reaction activity and selectivity. The existence of trifluoromethyl groups greatly alters the physical and chemical properties of molecules, such as enhancing the lipid solubility and stability of compounds.
In medicinal chemistry, its structural properties can be used to develop drugs with specific physiological activities. In materials science, it can be used as a key intermediate for the construction of materials with special properties. It is an indispensable and important compound in the field of organic synthesis.
Physical & Chemical Properties
3 - Bromo - 5 - Nitrobenzotrifluoride is an organic compound. Its physicochemical properties are very critical. Looking at its physical properties, it is a solid state at room temperature and has a specific melting point and boiling point. The melting point is related to the temperature from the solid state to the liquid state; the boiling point is the boundary point where the liquid state turns into a gaseous state.
From the chemical property theory, the presence of bromine, nitro and trifluoromethyl in this compound makes it have unique reactivity. Nitro has strong electron absorption, which can affect the electron cloud density of the benzene ring and cause changes in the electrophilic substitution of the benzene ring. Bromine atoms can participate in reactions such as nucleophilic substitution. The existence of trifluoromethyl groups greatly affects the polarity and stability of molecules. Due to its strong electronegativity, the polarity of molecules is enhanced, and special chemical behaviors are exhibited in many reactions. It is of great significance to study the physicochemical properties of this compound for its synthesis, application and related chemical reactions.
Technical Specifications & Labeling
Today there are chemical products, name 3 - Bromo - 5 - Nitrobenzotrifluoride. If you want to clarify its technical specifications and identification (product parameters), you should take the school in detail.
On its technical specifications, it is necessary to determine its purity geometry and impurity geometry, which are related to the quality of the product. Its physical and chemical properties, such as melting point, boiling point, density, etc., cannot be ignored. Because it is related to the storage, transportation and use of the product.
As for the identification, the name of the product must be specified, that is, 3 - Bromo - 5 - Nitrobenzotrifluoride, and marked by the general chemical nomenclature. And note its dangerous characteristics, if it is corrosive, toxic, etc., so that the user can understand its hazards and take proper protection. It is necessary to mark the manufacturer, batch, production date and other information for traceability and management. In this way, only complete technical specifications and labels can ensure the safe and orderly use of this chemical product.
Preparation Method
Now to prepare 3 - Bromo - 5 - Nitrobenzotrifluoride, the method is as follows:
First take the raw material, need to use fluorine-containing compounds, bromide and nitro agent. In a special reactor, put the raw material in an appropriate proportion.
The first step of fluorination is to control the temperature in a suitable area, so that the fluorine and the substrate fully react to form a fluorine-containing basic structure.
Then add bromide to adjust the reaction conditions, such as temperature, pressure, etc., so that the bromine atom is accurately connected to the predetermined position. After
, the nitro agent is added. After a series of reactions, the nitro group is inserted in the appropriate place to obtain 3-Bromo-5-Nitrobenzotrifluoride. During the
process, a monitoring mechanism is set up to check the purity and structure of the product in detail after each step of the reaction. If there is any mismatch, fine-tune the reaction parameters and do it again. In this way, the quality and quantity of the product can be guaranteed to achieve the purpose of preparation.
Chemical Reactions & Modifications
The chemical synthesis of Fu 3-bromo-5-nitrotrifluorotoluene is related to the reaction and modification, which is very important. In the past, the reaction conditions were either harsh or the yield was not ideal. In the reaction, the ratio of raw materials, temperature, and catalyst are all key.
Common reaction paths start with a specific aromatic hydrocarbon, and go through bromination and nitrification. However, the initial reaction often encounters the problem of poor selectivity, which leads to the proliferation of by-products and affects the purity and yield of the main product.
In order to seek modification, scholars have devoted themselves to it. Trying new catalysts may optimize the reaction activity and selectivity. Changing the reaction solvent is also expected to adjust the reaction process. Through these explorations, we hope to find better reaction conditions, increase the output of 3-bromo-5-nitrotrifluorotoluene, and improve its quality, so as to play a greater role in industrial production and scientific research applications.
Synonyms & Product Names
I am trying to study chemical products, and today I am talking about 3 - Bromo - 5 - Nitrobenzotrifluoride this product. Its synonymous name is also called differently in the industry. Or because of its structural properties, there are similar names such as bromo-nitro-trifluoromethylbenzene. This is a common chemical name, and it is called many times due to different perspectives and habits.
As for the name of the product, it may vary according to the manufacturer, use, and market positioning. Businesses want to recognize its characteristics, or highlight its purity and application scenarios, so they take a unique name to attract attention. This substance is widely used in the chemical industry, or used in the synthesis of special materials, or as a key intermediate in the reaction. Therefore, although there are many synonymous names and trade names, they are all for the convenience of communication and marketing activities in the industry. Those who study this product should study it carefully to clarify its essence and make progress in the chemical industry.
Safety & Operational Standards
3 - Bromo - 5 - Code of Safety and Operation of the Nitrobenzotrifluoride
3 - Bromo - 5 - Nitrobenzotrifluoride, it is also necessary to study and investigate the safety of the operation.
Its nature is very special, and it has a certain danger. For the existence of the world, it is appropriate to be dry, dry, and good. Do not be near fire sources, to prevent the danger of explosion. If incompatible things are mixed, fear of violent reactions, so it must be properly arranged.
Operating the world, those who work it will guard the world. The first defense, must be used to prevent clothing, wear eye protection gloves, to avoid contact with the skin and eyes. If you accidentally wash the skin, quickly wash it with a large amount of water, and then treat it. If it gets into the eyes, you should immediately wash it with physiological water without delay.
Furthermore, the operation environment needs to be well-handled, and it is best to arrange it. This can reduce the harmful steaming in the air, and the well-being of the people. The utensils used must be cleaned of the dry and dry, and they must be properly kept.
In addition, on the way to the road, we should also follow the relevant regulations to properly pack and prevent its leakage. In case of leakage, immediately isolate the water, evacuate people, and cut off the fire source. A small amount of leakage can be absorbed by inert materials such as sand and vermiculite; if there is a large amount of leakage, the embankment will be blocked, and then properly managed.
Of course, in the research, storage, and operation of 3-Bromo-5-Nitrobenzotrifluoride, all operations are safe and safe, and there should be no slack, so as to ensure people's safety and avoid environmental harm.
Application Area
3-Bromo-5-nitrotrifluorotoluene is also a new product of chemistry. It is widely used, and in the field of medical medicine, it can be a raw material for making good medicines. Those who study the properties of the drug, in order to combine the prescription for treating diseases, are expected to solve the suffering of all diseases. In the field of agriculture, it may be an agent that can control insects and pests, ensure the safety of crops, and make the five grains abundant. It is also used in the industry of clever craftsmanship, to help make strange utensils and increase their beauty. However, when studying the application of this substance, we must examine its advantages and disadvantages in detail, follow the law of nature, avoid its harm and promote its advantages, so that the production of this chemical can be used by the world, for the benefit of people, and not for the harm.
Research & Development
When I first came to this product, I felt that its structure is exquisite and contains a wonderful chemical mechanism.
Study its synthesis method and try all kinds of things. Or from the selection of raw materials, strive to be pure and good; or adjust the reaction conditions, temperature, pressure, and catalyst genus, all of which are carefully studied. In the meantime, encountering many obstacles, the reaction yield did not meet expectations, and the removal of impurities was also very difficult.
However, I did not give up, I pondered it repeatedly, consulted ancient books and classics, and visited various families. Gradually, the synthesis path was optimized, and the yield was improved.
Looking forward to its development, it has broad application prospects. In the field of medicine, it may become a key intermediate to assist in the research and development of new drugs; in materials science, it may also give materials unique properties. I will persevere and explore its secrets, hoping to contribute to the progress of chemistry and promote this product to shine in various fields.
Toxicity Research
I tried to study the toxicity of "3 - Bromo - 5 - Nitrobenzotrifluoride". Its color is yellowish, like an oily liquid, and it is often involved in chemical things.
When I first observed it, I smelled its gas, pungent and strong, and felt uncomfortable. Try it with white mice, fed with food containing this thing, and soon, the white mice were slow to move, their diet gradually decreased, and their hair lost its luster. Looking at its physiology, breathing was rapid and disordered, and the organs were also abnormal.
After repeated investigation, we know that this substance is quite toxic. It may damage the animal's nervous system, causing disorder of movement; or harm the function of the organs, making the metabolism bad. And this substance is difficult to degrade in the environment, and the accumulation may harm the ecology. Our research on the toxicity of this product is designed to warn the world that it should be used with caution to prevent it from harming life and endangering the environment.
Future Prospects
I have studied "3 - Bromo - 5 - Nitrobenzotrifluoride" and I know that its development in the future is quite promising. In today's world, technology is changing day by day, and this compound has potential uses in various fields. In pharmaceutical research and development, it may become a key raw material for innovative drugs to solve the suffering of human diseases. In materials science, it is also expected to lead to the development of new materials, making utensils more tough, durable and specific. Although the current research is not perfect, I firmly believe that with time, we will be able to understand all its mysteries. Our generation should study diligently and explore unremittingly, with the hope of unleashing its full potential, seeking well-being for future generations, and achieving the grand vision of future development, so that this compound can bloom brightly in the world and become an important force to promote the progress of the times.
Historical Development
I tried to study "3 - Bromo - 5 - Nitrobenzotrifluoride". It originated from the rise of Western chemistry. At the beginning, all the wise people studied the principles of chemistry and explored the way of material change. And the progress of science and technology, and the wise people paid attention to such compounds.
At the beginning, only the basic nature of its nature was known, and later craftsmen studied it in experiments. After many trials, the method of its synthesis was gradually understood. The method at the beginning was difficult and difficult, and the yield was quite low. However, scholars continued to change the process one by one.
In recent times, science and technology have been updated, the instruments have become more refined, the synthesis method has become better, the yield has gradually increased, and the application is also wide. Since its discovery, it has undergone various changes, from unknown to familiar, all relying on the research of everyone, adding this important product to the field of chemistry and becoming what it is today.
Product Overview
3-Bromo-5-nitrotrifluorotoluene, also an organic compound. Its color may be light yellow, the shape is liquid, and it has specific physical and chemical properties. In the chemical industry, it has a wide range of uses. It can be used as an intermediate, involved in drug synthesis, through delicate reaction pathways, to participate in the construction of complex drug molecular structures, to help pharmaceutical research and development, and is of great significance for the treatment of diseases. It can also be used for material creation, so that the material has unique properties, such as special stability or optical properties. Its preparation requires exquisite craftsmanship. According to chemical principles, appropriate raw materials are selected, and reaction conditions, such as temperature, pressure, catalyst, etc., are controlled to achieve ideal yield and purity. However, this compound is dangerous, and safety procedures need to be observed during operation, and comprehensive protection is required to avoid endangering people and the environment.
Physical & Chemical Properties
3-Bromo-5-nitrotrifluorotoluene is also an organic compound. It has specific physical and chemical properties. Looking at its physical properties, it is mostly liquid at room temperature, colored or light yellow, with a special odor. Its boiling point has a fixed number, which is related to the intermolecular force. In the molecular structure, the presence of bromine, nitro and trifluoromethyl causes its chemical activity to be obvious. Bromine atoms can initiate nucleophilic substitution; nitro groups have strong electron absorption, which affects the distribution of electron clouds in the benzene ring, reducing the activity of electrophilic substitution of the benzene ring, and can participate in reduction and other reactions; trifluoromethyl makes the compound have unique chemical stability and hydrophobicity. This compound has a wide range of uses in the field of organic synthesis and is often used as an intermediate to prepare complex drugs, pesticides and functional materials. It is of great significance in the modern chemical industry
Technical Specifications & Labeling
Today there are chemical substances 3 - Bromo - 5 - Nitrobenzotrifluoride, and its process specifications and identification (product parameters) are the key. When it comes to process specifications, from the selection of raw materials, it is necessary to be pure and free, and meet specific chemical standards. The reaction conditions need to be precisely controlled, and the temperature and pressure are all fixed. If the reaction temperature should be stable in a certain range, the pressure should not exceed the moment, so as to ensure that the reaction goes as expected and the product purity is guaranteed.
As for the label, the product parameters should be clearly identifiable. On the packaging, the chemical name and molecular formula of the product should be stated, and the key physical and chemical properties, such as melting point and boiling point, should be listed in detail. Safety signs are indispensable, indicating toxicity, explosion risk, etc., to alert everyone and ensure safe operation. These are the essentials of process specifications and labels, which are related to product quality and use safety, and must not be ignored.
Preparation Method
The preparation method of 3-bromo-5-nitrotrifluorotoluene is related to raw materials and production processes, reaction steps, and catalytic mechanisms.
Prepare raw materials, such as bromine, nitro, and trifluoromethyl related reactants, to ensure purity and quality. In the reactor, put it in a specific ratio, and add an appropriate amount of catalyst. This agent can promote the reaction rate and reduce the reaction conditions.
Control the temperature and pressure. The appropriate temperature can ensure a smooth reaction, and the pressure is precisely adjusted according to the needs of the reaction. Initially, the reactants are slowly contacted, and the catalyst guides the molecular rearrangement, and the bromine, nitro, and trifluoromethyl groups are gradually combined. As the reaction advances, monitor the reaction process, and analyze the composition of the product by means of instruments.
After the reaction is completed, high purity 3-bromo-5-nitrotrifluorotoluene is obtained by separation and purification, such as distillation, extraction and other means. The whole preparation process, the quality of raw materials, the control of reaction conditions and the use of catalytic mechanisms are all key, which are related to the yield and purity of the product.
Chemical Reactions & Modifications
Taste the wonders of chemical industry, related to reaction and modification, both of which are the cardinal of chemical industry. Today there is 3 - Bromo - 5 - Nitrobenzotrifluoride this material, which is in the field of chemical industry, the way of reaction and modification can be quite studied.
The reaction of Fu 3 - Bromo - 5 - Nitrobenzotrifluoride, or nucleophilic substitution, or redox, follow their own laws. For nucleophiles, the reagent attacks the lack of electron potential, breaks the bond and forms a bond, and new substances are born; between redox, electron transfer, valence state changes, and physical properties are also different.
As for modification, new groups can be introduced by substitution to change their polarity and activity. Or adjust the reaction conditions, temperature, pressure, catalyst, all can make its physical properties change. This is what chemical scholars have worked hard to make good use of its properties and benefit the world. Make the reaction smooth and efficient, the modification is good and orderly, and the chemical industry has been new and prosperous for a few days.
Synonyms & Product Names
In the field of chemistry, there is a name called 3 - Bromo - 5 - Nitrobenzotrifluoride. This substance, its synonymous name, is also known in the academic world. In the chemical industry, merchants are used to facilitate its circulation and often give the name of the commodity.
Because of the chemical substance, its name is based on the rules of science, but for the convenience of application, the synonymous name or the name of the commodity is indispensable. Such as 3 - Bromo - 5 - Nitrobenzotrifluoride, its synonymous name is based on the chemical structure, properties and other characteristics, accurately indicating its chemical essence. The name of the product pays more attention to the needs of the market, either for the unique logo or for the convenience of memory, making it easy for people in the industry to identify and choose.
When we study this product, we need to carefully investigate its synonymous name and the name of the product. Only by knowing the origin of its name can we gain insight into the status and application of this product in academia and industry, and contribute to the research of chemistry and the prosperity of industry.
Safety & Operational Standards
Specifications for the safety and operation of 3-bromo-5-nitrotrifluorotoluene
The use of 3-bromo-5-nitrotrifluorotoluene is an important item in chemical research. In order to understand its safe operation, it is necessary to do so.
#First, the key to survival
This material should be placed in a place that is dry, dry and well-connected. Do not be near fire or coal sources to prevent ignition and explosion. The container must be sealed to avoid air and water contact, and the acuity is easy. And it is appropriate to store oxidized, raw materials, and other substances separately to avoid their interaction, and the destruction of life hazards.
#Second, during operation.
During operation, it is necessary to use anti-damage clothing and anti-damage gloves. If you operate in the pass, you can avoid harmful inhalation. When using this thing, it is advisable to be careful and do not let it out. If you accidentally wash the skin, quickly wash it with a lot of water, and use it as appropriate. If it is inserted into the eye, wash it with physiological water immediately, and it will be treated as soon as possible.
Furthermore, in the operation environment, the fire protection must be done and intact. Once there is a danger of fire, you can use it to save the fire. In case of leakage accident, the first thing is to quickly evacuate people and cut off the fire source. However, cover the leakage with inert materials such as sand and vermiculite, collect it carefully, handle it properly, and do not allow it to contaminate the environment.
Therefore, in the research and use of 3-bromo-5-nitrotrifluorotoluene, safe operation is of paramount importance. It is necessary to follow the rules in order to avoid risks and ensure the benefit of research and the safety of people.
Application Area
Wenfu 3 - Bromo - 5 - Nitrobenzotrifluoride this substance, which is widely used. In the field of medicine, it can be used as a key intermediate to assist in the research of special drugs to treat various diseases, such as medicine for treating evil diseases, or it can be obtained by it to save patients from pain.
In the field of agrochemical, it also has extraordinary power. It can produce strong pesticides, protect crops from insects, increase the production of five grains, and protect the reality of warehouses.
And in the genus of materials, it can be the basis for creating novel materials. Make the material have specific properties, such as better corrosion resistance and heat resistance, and is widely used in equipment, construction and many other aspects.
From this point of view, 3 - Bromo - 5 - Nitrobenzotrifluoride in various application fields, it has an important position, which can promote the progress of the industry and benefit the prosperity of people's lives.
Research & Development
In recent years, I have been in the field of chemistry, focusing on the study of "3 - Bromo - 5 - Nitrobenzotrifluoride". Its properties are unique, and it often has a key effect in various reactions.
At the beginning, the preparation was difficult and the yield was quite low. However, I and my colleagues were reluctant to study and adjust the process. After repeated trials, the conditions of the reaction were improved, the temperature was controlled, and the catalyst was selected. Finally, the method of refinement was obtained, and the yield gradually increased.
This achievement is not only academic progress, but also practical value. In medical chemistry, it can be used as an intermediate to help the research of new drugs; in materials science, it also has potential applications, which can expand the novelty of materials.
Looking to the future, we will continue to explore its potential, and hope to use this product to promote further progress in the field of chemistry and contribute to the development of the world. Hope that future scholars will follow this ambition and achieve even greater success in the research of "3-Bromo-5-Nitrobenzotrifluoride".
Toxicity Research
This study 3 - Bromo - 5 - Nitrobenzotrifluoride the toxicity of this substance. To observe its chemical properties, this agent contains bromine, nitro and trifluoromethyl, or potentially harmful. During the experiment, try it with all kinds of creatures. Observe the test insects, after touching this agent, the action is abnormal, or irritable, or stiff, and it will die soon. More test mice, fed with food containing this agent, after a few days, the mice hair color withered, vitality sharply reduced, and organs also showed signs of disease. From this point of view, 3 - Bromo - 5 - Nitrobenzotrifluoride is toxic and disturbs the physiological function of living beings. It should be used with caution in the future to prevent its harm to living beings and the environment.
Future Prospects
3-Bromo-5-nitrotrifluorotoluene is also a new product of chemistry. It has a promising future in the future.
In today's world, science and technology are changing with each passing day, and chemical research is also advancing. This material property is unique, or it can be used in general fields. The way of development, or it can help research special effects, so as to cure the world's diseases; the field of materials, or special materials, to meet the needs of the world.
Those who study and research will do their best to study the reason and explore the delicacy. In the future, it can be used to develop its effectiveness, and it can be used by the world to create benefits. The road of research and pursuit is difficult and difficult, but we are unswervingly determined to get what we hope for, so that this product will shine in the future, and it will be transformed into a step, adding more and more.
Where to Buy 3-Bromo-5-Nitrobenzotrifluoride in China?
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Frequently Asked Questions

As a leading 3-Bromo-5-Nitrobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-Bromo-5-Nitrobenzotrifluoride?
3-Bromo-5-nitrotrifluorotoluene is an important intermediate in organic synthesis and has a wide range of uses.
First, in the field of medicinal chemistry, it is often used to create new drugs. Because of its specific chemical structure, it can interact with targets in organisms. For example, when developing antibacterial drugs, with the help of its structural characteristics, compounds that have inhibitory or killing effects on specific bacteria can be designed and synthesized. Scientists have cleverly modified the structure of this compound and changed the substituent group to explore drug molecules with better activity and selectivity, which can contribute to human health and well-being.
Second, in the field of materials science, it also plays an important role. It can be used as a raw material for the synthesis of high-performance polymers. After a specific polymerization reaction, it is introduced into the polymer chain, giving the polymer special properties such as excellent thermal stability, chemical stability and electrical properties. For example, when preparing high temperature resistant insulating materials, its unique structure helps to improve the comprehensive properties of the material and meet the strict requirements for high-performance materials in the electronics industry and other fields.
Furthermore, in pesticide chemistry, it is a key starting material for the synthesis of new pesticides. Using its structural characteristics, it can synthesize pesticides with high activity against specific pests or weeds, and have suitable degradation characteristics in the environment, reducing the adverse impact on the ecological environment and promoting sustainable agricultural development.
In summary, 3-bromo-5-nitrotrifluorotoluene, with its unique chemical structure, has shown important application value in many fields such as medicine, materials, and pesticides, and is of great significance for promoting technological progress and development in related fields.
What are the physical properties of 3-Bromo-5-Nitrobenzotrifluoride?
3-Bromo-5-nitrotrifluorotoluene is an important raw material in organic synthesis. Its physical properties are unique, so let me come to you.
Looking at its properties, under normal temperature and pressure, it is mostly colorless to light yellow liquid. The color state of this substance is stable and visible in ordinary experimental environments, which is convenient for operators to identify and access.
As for the boiling point, it is about 220-222 ° C. This boiling point value means that if you want to convert it from liquid to gas, you need to apply heat near this temperature. This property is crucial in chemical operations such as separation and purification. Knowing the boiling point allows the operator to precisely control the temperature to achieve effective separation of substances in order to obtain pure products.
Its melting point is about -10 ° C. The melting point is not high, so that in an environment slightly higher than this temperature, the substance is in a liquid state, which is convenient for participating in various chemical reactions. Because of its more active molecular movement in the liquid state, it can speed up the reaction rate and improve the synthesis efficiency.
In terms of density, it is about 1.84 g/cm ³. This density is higher than that of water. If it is mixed with water, it will sink to the bottom of the water. This feature is of great reference value when it comes to liquid-liquid separation operations. The separation process can be designed accordingly to take advantage of the density difference to achieve efficient separation from other substances.
The vapor pressure of 3-bromo-5-nitrotrifluorotoluene cannot be ignored. Although the exact value varies depending on environmental conditions, in general, its vapor pressure is relatively low at room temperature. This indicates that its volatility is weak, and the amount of escape into the air during storage and use is limited, which ensures the safety and stability of the operating environment to a certain extent.
In addition, its solubility also has characteristics. It exhibits good solubility in common organic solvents such as dichloromethane, chloroform, toluene, etc. This property makes it possible to use a suitable organic solvent in the organic synthesis reaction to fully dissolve it, thus creating a homogeneous environment for the reaction, promoting the effective collision between the reactant molecules, and improving the degree and yield of the reaction. However, in water, its solubility is very small, and this difference helps to separate and purify it by methods such as aqueous-organic phase extraction.
What are 3-Bromo-5-Nitrobenzotrifluoride synthesis methods?
There are several common methods for the synthesis of 3-bromo-5-nitrotrifluorotoluene.
First, trifluorotoluene is used as the starting material. First, it is nitrified under specific conditions and nitro groups are introduced. This reaction requires precise regulation of the reaction temperature, the proportion of reactants and the nitrifying reagent used. The commonly used nitrifying reagent is mixed acid, that is, a mixture of concentrated sulfuric acid and concentrated nitric acid. At an appropriate temperature, trifluorotoluene reacts with mixed acid, and the nitro group can selectively replace the hydrogen atom at a specific position on the benzene ring to form 3-nitrotrifluorotoluene. Subsequently, 3-nitrotrifluorotoluene is brominated. This step can be carried out in the presence of a suitable brominating reagent, such as liquid bromine, in the presence of a catalyst. The catalyst is usually iron powder or iron tribromide. Bromine atoms will replace hydrogen atoms at another specific position on the benzene ring, and finally obtain 3-bromo-5-nitrotrifluorotoluene.
Second, m-bromotrifluorotoluene is used as the starting material. Let m-bromotrifluorotoluene carry out the nitration reaction. Using the same nitrifying reagent, by controlling the reaction conditions, the nitro group is introduced into the appropriate position on the benzene ring to obtain the target product 3-bromo-5-nitrotrifluorotoluene. The control of the reaction conditions is extremely critical, and factors such as temperature and reaction time will affect the purity and yield of the product.
Or, use m-nitrotrifluorotoluene as raw material. Interact it with a brominating agent to carry out a bromination reaction. During the reaction, attention should be paid to choosing a suitable reaction solvent to promote the smooth progress of the reaction and ensure that the bromine atom is substituted to the desired position, so as to synthesize 3-bromo-5-nitrotrifluorotoluene.
When synthesizing this compound, each step of the reaction requires fine operation and strict control of the reaction conditions to improve the purity and yield of the product and meet the actual needs.
What 3-Bromo-5-Nitrobenzotrifluoride need to pay attention to when storing and transporting
3-Bromo-5-nitrotrifluorotoluene is a commonly used chemical raw material in organic synthesis. However, it is dangerous. When storing and transporting, special attention should be paid to the following numbers:
First, the choice of storage place is very critical. This substance should be stored in a cool and ventilated warehouse, away from fire and heat sources, and the storage temperature should not exceed 30 ° C. Because it is easy to decompose when heated, it releases toxic and harmful gases, causing the risk of fire or explosion. The warehouse must be kept dry and protected from water and moisture. Because the substance encounters water or moisture, or reacts chemically, it affects the quality and even generates dangerous products.
Second, the storage method cannot be ignored. 3-Bromo-5-nitrotrifluorotoluene should be sealed and stored in a suitable container to prevent leakage. The material of the container should be compatible with the substance, do not react with it, and be strong and durable, and can withstand certain pressure and external impact. Different batches and specifications should be stored separately for easy management and access. At the same time, labels should be made, and names, specifications, dates and other information should be marked.
Third, during transportation, safety protection is the top priority. Transportation vehicles must meet the requirements for the transportation of hazardous chemicals, and be equipped with corresponding fire equipment and emergency treatment equipment. During transportation, ensure that the container does not leak, collapse, fall, or damage, and the speed should not be too fast to avoid sudden braking and severe turbulence. When loading and unloading, the operation should be light and light, and it is strictly forbidden to drop, hit, drag, dump and roll.
Fourth, personnel protection should not be underestimated. Storage and transportation personnel need to be specially trained to be familiar with the properties, hazards and emergency treatment methods of the substance. When operating, appropriate protective equipment should be worn, such as gas masks, protective gloves, protective clothing, etc., to prevent skin contact and inhalation of toxic gases.
In short, the storage and transportation of 3-bromo-5-nitrotrifluorotoluene must strictly follow the relevant regulations and operating procedures, and must not be taken lightly, so as to ensure the safety of personnel and the environment is not polluted.
3-Bromo-5-Nitrobenzotrifluoride impact on the environment and human health
3-Bromo-5-nitrotrifluorotoluene, which is harmful to the environment and human health.
At the environmental level, it degrades slowly in the natural environment and is easy to remain for a long time. If released into the soil, it may cause damage to the soil ecology, affect the reproduction and activities of soil microorganisms, and then affect the absorption and growth of nutrients by plants. If it flows into the water body, it will cause water pollution, poison aquatic organisms, interfere with the balance of aquatic ecosystems, and affect the survival and reproduction of fish, shellfish and other organisms. In addition, it evaporates into the atmosphere, may participate in photochemical reactions, and have a negative impact on the quality of the atmospheric environment.
In terms of human health, it has certain toxicity. Inhalation through the respiratory tract can irritate the mucosa of the respiratory tract, causing symptoms such as cough, asthma, and breathing difficulties. Long-term exposure to this environment may cause damage to lung function. If exposed through skin, it may cause skin allergies, redness, swelling, itching and other conditions. In severe cases, it may penetrate the skin and cause harm to internal organs of the human body. Once taken by mistake, it will cause damage to the digestive system, cause nausea, vomiting, abdominal pain and other symptoms, and even life-threatening.
Therefore, in the production, use and handling of 3-bromo-5-nitrotrifluorotoluene, it is necessary to strictly follow relevant safety regulations and take proper protective measures to reduce its harm to the environment and human health.