3 Bromo 5 Chlorobenzotrifluoride
Fluoride
3-Bromo-5-Chlorobenzotrifluoride
Chemical Formula C7H3BrClF3
Molecular Weight 261.45
Appearance Colorless to light yellow liquid
Boiling Point 198 - 200 °C
Melting Point N/A
Density 1.744 g/cm³
Solubility Insoluble in water, soluble in organic solvents
Flash Point 83 °C
Vapor Pressure N/A
Refractive Index 1.486 - 1.488
FAQ

What are the main uses of 3-Bromo-5-Chlorobenzotrifluoride?

3-Bromo-5-chlorotrifluorotoluene has a wide range of uses. In the field of pharmaceutical synthesis, it is often a key intermediate. The compound has a unique chemical structure and can be converted into many substances with specific pharmacological activities through various chemical reactions, which can be used to create new drugs, such as antibacterial, antiviral, and anti-tumor drugs.

In the field of pesticide research and development, 3-bromo-5-chlorotrifluorotoluene also plays an important role. After a specific reaction, it can be introduced into the molecular structure of pesticides to enhance the poisoning effect of pesticides on pests, improve its stability and durability. For example, highly effective insecticides can be prepared for specific crop pests to ensure crop growth and prevent insect infestation.

Furthermore, in the field of materials science, it also has applications. Due to the fluorine atom, it can impart special properties to materials, such as corrosion resistance, low surface energy, etc. By using it as a raw material to participate in material synthesis reactions, polymer materials and coatings with special properties can be prepared, which can be used in aerospace, automobile manufacturing and other industries that require strict material properties.

In short, 3-bromo-5-chlorotrifluorotoluene has important uses in many fields such as medicine, pesticides, and materials science due to its unique chemical properties, and plays an important role in promoting technological development in various fields.

What are the physical properties of 3-Bromo-5-Chlorobenzotrifluoride?

3-Bromo-5-chlorotrifluorotoluene is one of the organic compounds. Its unique physical properties are listed below.

Looking at its properties, under room temperature and pressure, 3-bromo-5-chlorotrifluorotoluene is a colorless to light yellow liquid with a clear and special luster. This state is easy to detect and distinguish, and is a sign of the first recognition of this substance.

When it comes to the melting point, its melting point is about -30 ° C, and its boiling point is between 190-192 ° C. The melting point is low, making this substance a liquid at room temperature; the boiling point is relatively high, indicating that the intermolecular forces have a certain intensity, and more energy input is required to vaporize it.

As for the density, it is about 1.7g/cm ³, which is heavier than water. If it is co-located with water, it will sink underwater. This property is of great value when separating substances and related experimental operations.

In terms of solubility, 3-bromo-5-chlorotrifluorotoluene is insoluble in water. Due to the large difference between the hydrogen bonds between water molecules and the forces between the organic molecules, the two are difficult to dissolve. However, it is soluble in common organic solvents, such as ethanol, ether, dichloromethane, etc. Due to the principle of "similarity and miscibility", the molecular structure and polarity of the organic compound and the organic solvent are similar, and they can be miscible with each other. This is a commonly used characteristic in organic synthesis, extraction and other operations.

Its vapor pressure is low at room temperature, which means that its volatilization degree is limited. However, when the temperature increases, the vapor pressure also increases, and the volatilization intensifies. This is related to the stability and volatility of the substance under different temperature environments, and must be carefully considered when storing and using.

In summary, the physical properties of 3-bromo-5-chlorotrifluorotoluene have their own uses, which are important for the research of organic chemistry and the practice of industrial production. Only by understanding its properties can we make good use of this substance.

What is the chemistry of 3-Bromo-5-Chlorobenzotrifluoride?

3-Bromo-5-chlorotrifluorotoluene is an organic compound with unique chemical properties. Its properties are usually colorless to light yellow liquid, and it is widely used in the field of organic synthesis.

In terms of chemical activity, both bromine and chlorine atoms in this molecule are halogen atoms, which are highly active and can participate in many nucleophilic substitution reactions. For example, under appropriate conditions, hydroxyl groups, amino groups and other nucleophiles can replace bromine or chlorine atoms, and then form new carbon-heteroatomic bonds, thereby synthesizing organic compounds with diverse structures.

Due to the existence of trifluoromethyl groups, it has a significant impact on the distribution of molecular electron clouds. Trifluoromethyl has strong electron absorption, which decreases the electron cloud density of the benzene ring, increases the difficulty of electrophilic substitution reaction on the benzene ring, and changes the reaction check point. At the same time, the presence of trifluoromethyl increases the fat solubility of the compound, which affects its solubility in different solvents.

In terms of stability, the compound is quite stable at room temperature and pressure and under normal storage conditions. However, in case of hot topic, open flame or contact with strong oxidants, dangerous reactions may still occur.

Its boiling point, melting point and other physical properties are different from similar simple aromatic derivatives due to the interaction of atoms and functional groups in the molecular structure. These physical properties determine its separation, purification and storage methods.

In organic synthesis, 3-bromo-5-chlorotrifluorotoluene is a key intermediate. Through various chemical reactions, important compounds in the fields of medicine, pesticides, materials, etc. can be prepared, which is of great significance to the modern chemical industry.

What is 3-Bromo-5-Chlorobenzotrifluoride production method?

3-Bromo-5-chlorotrifluorotoluene is also an organic compound. There are many different ways to prepare it, and the common method is selected.

First, 3-chlorotrifluorotoluene is used as the starting material. First, 3-chlorotrifluorotoluene is reacted with a brominating agent, such as liquid bromine, in a suitable reaction vessel in the presence of a catalyst. The commonly used catalyst can be iron powder or iron tribromide. When the two are mixed and the appropriate temperature is controlled, the bromine atom in the brominating agent will selectively replace the hydrogen atom at a specific position on the benzene ring under the condition of heating and reflux. Due to the localization effect of the substituents on the benzene ring, the interaction between the chlorine atom and the trifluoromethyl makes the bromine atom mainly replace the hydrogen atom at the interposition with the chlorine atom and the interposition with the trifluoromethyl on the 3-chlorotrifluorotoluene benzene ring, thereby generating 3-bromo-5-chlorotrifluorotoluene. During this reaction, it is necessary to pay close attention to the change of the reaction temperature. Due to the high or low temperature, the reaction rate and product selectivity may be affected.

Second, 3-bromotrifluorotoluene can also be used as the starting material. Let 3-bromotrifluorotoluene react with a chlorination agent, such as chlorine gas, in the presence of a suitable catalyst, such as anhydrous aluminum Under suitable reaction conditions, such as in a certain temperature and pressure environment, the chlorine atoms in chlorine gas will undergo a substitution reaction. Due to the positioning rules of the substituents, the chlorine atoms will selectively enter specific positions on the benzene ring, and finally form the target product 3-bromo-5-chlorotrifluorotoluene. In this process, factors such as the purity of the reaction system and the proportion of the reactants have a great influence on the reaction results and need to be carefully regulated.

There may be other synthesis methods, but the above two are common ways to prepare 3-bromo-5-chlorotrifluorotoluene. When preparing, it is necessary to follow the standard operation of chemical experiments and pay attention to safety protection to ensure the smooth progress of the reaction and obtain a pure product.

What are the precautions in storage and transportation of 3-Bromo-5-Chlorobenzotrifluoride?

3-Bromo-5-chlorotrifluorotoluene is an organic compound. When storing and transporting, many matters need to be paid attention to.

When storing, the first environment should be heavy. Choose a cool, dry and well-ventilated place. This is because the compound is quite sensitive to heat and humidity. If it is placed in a high temperature or humid place, it may cause deterioration or even cause dangerous reactions. If it is placed in a warehouse with hot and humid weather in the hot season, it is easy to change the properties of the compound.

Furthermore, it is necessary to keep away from fire and heat sources. Because of its flammability, it may encounter open flames, hot topics, or risk of combustion and explosion. In the warehouse, fireworks are strictly prohibited, and electrical equipment must also meet explosion-proof standards. < Br >
Storage containers are also crucial. When using a sealed container to prevent volatilization and leakage. And the material must be compatible with the compound. If a container with improper material is used, it may cause corrosion of the container and cause leakage accidents.

When transporting, the packaging must be tight. According to its characteristics, choose the appropriate packaging material to ensure that it will not be damaged or leaked during transportation. Loading and unloading, the operation should be cautious to avoid collisions, falls, damage and packaging.

Transportation tools are also required. Do not mix with oxidants, acids and alkalis, etc., because it encounters with these substances or reacts violently. During transportation, pay close attention to changes in temperature and humidity and adjust it in a timely manner.

In conclusion, the storage and transportation of 3-bromo-5-chlorotrifluorotoluene must be treated strictly in all aspects. If there is a slight mistake, it may lead to a disaster, and it must be operated in accordance with regulations to ensure safety.