3 Bromo 4 Chlorobenzotrifluoride
Fluoride

3-Bromo-4-Chlorobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

660508

Chemical Formula C7H3BrClF3
Molar Mass 261.45 g/mol
Appearance Colorless to light yellow liquid
Boiling Point Around 198 - 200 °C
Density Approx. 1.74 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
Vapor Pressure Low vapor pressure at room temperature
Name 3 - Bromo - 4 - Chlorobenzotrifluoride
Molecular Formula C7H3BrClF3
Molar Mass 273.45 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 195 - 197 °C
Melting Point N/A
Density 1.738 g/mL at 25 °C
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Vapor Pressure Low
Flash Point 80 °C
Purity Typically high - purity (>95% in commercial products)

As an accredited 3-Bromo-4-Chlorobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottle of 3 - Bromo - 4 - Chlorobenzotrifluoride, well - sealed for chemical storage.
Storage 3 - Bromo - 4 - Chlorobenzotrifluoride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials. Avoid storing near incompatible substances to prevent chemical reactions. This ensures its stability and safety during storage.
Shipping 3 - Bromo - 4 - Chlorobenzotrifluoride is shipped in specialized, well - sealed containers compliant with chemical transport regulations. Shipment ensures protection from physical damage and environmental exposure during transit.
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3-Bromo-4-Chlorobenzotrifluoride
General Information
Historical Development
3-Bromo-4-chlorotrifluorotoluene, the development of this compound can be traced back to the past. Although its origin is difficult to study in detail, the path of chemical evolution is gradually emerging. Early chemical industry was first developed, exploring various synthesis methods, and many scholars devoted themselves to it. Although the technology was not perfect at that time, it was tried unremitting, and it was finally successful. With the passage of time, science and technology have advanced, and experimental methods have become more refined, and the understanding of its properties and synthesis paths has deepened. In the past, synthesis was difficult and the yield was meager. Today, the process has been improved and the efficiency has greatly increased. Many researchers have made extraordinary contributions during this period, promoting this compound from ignorance to clarity with wisdom and sweat, leaving a deep imprint on the long history of chemical industry. Its development has witnessed the journey of chemical exploration and laid the foundation for more breakthroughs in the future.
Product Overview
There is a compound called 3 - Bromo 4 - Chlorobenzotrifluoride. It is an organic compound with a special structure. Looking at its appearance, it is a colorless to pale yellow liquid with relatively stable properties.
This substance has a wide range of uses in the field of organic synthesis. It can be used as a key intermediary for the preparation of a variety of fine chemicals. Due to the presence of bromine, chlorine and trifluoromethyl in the molecule, it has unique reactivity.
During the reaction, bromine and chlorine atoms can introduce other functional groups through reactions such as nucleophilic substitution to expand the variety of compounds. The strong electron-absorbing properties of trifluoromethyl also have a significant impact on the selectivity and activity of the reaction.
It is of great value in the chemical industry or the pharmaceutical industry, and can help develop novel materials and drugs, with promising prospects.
Physical & Chemical Properties
3-Bromo-4-chlorotrifluorotoluene is also an organic compound. Its physical and chemical properties are related to many aspects. Looking at its properties, it can be a colorless to pale yellow liquid at room temperature, with a special odor. Its boiling point can be determined to obtain a certain value, which is related to its phase transition under specific conditions. The melting point is also a key physical property, which affects its morphology at low temperature.
In terms of chemical properties, the molecule contains halogen atoms such as bromine and chlorine, which have certain reactivity. It can participate in nucleophilic substitution reactions, and halogen atoms can be replaced by other nucleophilic reagents, thereby deriving a variety of compounds. It contains trifluoromethyl, which makes the molecule have unique electronic and spatial effects, which affects its chemical stability and reaction selectivity. These physicochemical properties are of great significance in the fields of organic synthesis, laying the foundation for related research and applications.
Technical Specifications & Labeling
Today there is a thing called 3 - Bromo 4 - Chlorobenzotrifluoride. Its production method is related to technical specifications and identification (product parameters), which is really important.
To make this thing, the amount of various materials should be known first, and the ratio should be accurate. When reacting, control the temperature and duration to make it in line with the regulations. The utensils used in the meantime should also be clean and intact to avoid staining.
The method of marking it must list the characteristics of this thing in detail, such as color, taste, state, and the parameters of purity and content should be clear. In this way, the requirements of technical specifications and identification (product parameters) should be combined to make a good product.
Preparation Method
To make 3 - Bromo - 4 - Chlorobenzotrifluoride, take the raw materials first. Start with a halogenated aromatic hydrocarbon and adapt it to related reagents containing bromine, chlorine and trifluoromethyl. The preparation process is as follows:
In the first step, the halogenated aromatic hydrocarbon and a specific brominating reagent are mixed in a suitable solvent, the temperature is controlled and stirred, so that the bromine atom precisely replaces the specific position of the aromatic hydrocarbon to obtain the intermediate product. In this step, pay attention to the reaction temperature and time to avoid side reactions.
In the second step, put the obtained intermediate product into the reactor in proportion with the chlorination reagent, and adjust the reaction conditions to promote the substitution of the chlorine atom in the predetermined position to obtain the product containing bromine and
In the last step, the above product is reacted with the reagent introduced into the trifluoromethyl group under the catalytic system to construct the target product 3-Bromo-4-Chlorobenzotrifluoride. In the process, the catalytic mechanism is very critical, and the conditions of each reaction link need to be strictly controlled to ensure the smooth reaction and improve the purity and yield of the product. In this way, the required 3-Bromo-4-Chlorobenzotrifluoride can be obtained.
Chemical Reactions & Modifications
The wonders of chemical industry are related to the change of substances. In 3 - Bromo - 4 - Chlorobenzotrifluoride, the chemical reaction and modification of this substance are worth exploring.
If you want to change its properties, you must understand the mechanism of its reaction. In this compound, the positions of bromine, chlorine and trifluoromethyl are all important parts of the reaction. The method of nucleophilic substitution can be used to attack the positions of bromine or chlorine with suitable nucleophilic reagents, so that new groups can be introduced to change its properties.
Or a reduction reaction can be performed to remove its halogen atoms to obtain products with different structures, and the properties will be changed accordingly. This can be adjusted according to the needs of the experiment, such as temperature, solvent, catalyst, etc., to achieve the expected change.
After modification, it can either increase its stability or change its solubility, which can be used in materials and medicine. Good study of its chemical response and change can expand its path, make the best use of it, and add brilliance to the chemical industry.
Synonyms & Product Names
Today there is a thing called 3 - Bromo 4 - Chlorobenzotrifluoride. The name of this thing is synonymous with the name of the commodity, and we should also study it.
The name of the synonym may be born from different academic perspectives and research veins. Some are named after a certain characteristic of its chemical structure, and some are named according to its reaction characteristics. As for the name of the commodity, the merchant always wants to be easy to remember, unique and able to recognize its characteristics.
In the field of my chemical research, scrutinizing its synonymous name can show the context of academic inheritance and evolution; examining the name of the commodity can know the needs of the market and the wisdom of marketing. If we explore the synonymous name of 3 - Bromo 4 - Chlorobenzotrifluoride, we can find the change of scholars' cognition of it in the past; looking at its trade name, we can also peek at the positioning of the object in the market. Therefore, the detailed study of the synonymous name and trade name of this object is of great significance in chemical research and marketing activities.
Safety & Operational Standards
There is a chemical object today, called 3-Bromo-4-Chlorobenzotrifluoride, which is related to the safety and operation specifications of this object, and should be detailed.
This object has specific chemical properties, and the procedures must be strictly followed when operating. For storage, it is advisable to store it in a cool, dry and well-ventilated place, away from fire and heat sources. Cover it or risk ignition. If you are not careful, you may be in danger of disaster.
When operating, make sure that the operator wears appropriate protective equipment, such as protective clothing, gloves, and goggles, to prevent this object from touching the skin and eyes and causing damage. If this object accidentally leaks in the operation room, the first thing to do is to quickly evacuate the surrounding crowd, set up warning signs, and prohibit people from approaching. Operators should wear professional chemical protective clothing, use suitable materials to collect leaks, and dispose of them properly, so as not to pollute the environment.
Furthermore, in the experimental or production site where this object is used, fire protection facilities should be complete, and the ventilation system must be unobstructed to disperse the harmful gases that may escape. Operators should also be familiar with emergency response methods. In case of fire, leakage and other accidents, they can quickly rescue and dispose of it.
In short, the safety and operating practices of 3 - Bromo - 4 - Chlorobenzotrifluoride should not be ignored in order to ensure the safety of personnel, the environment and the smooth operation of production experiments. Anyone involved in this matter should be careful and follow this specification to avoid all risks.
Application Area
Today there is a product, named 3 - Bromo 4 - Chlorobenzotrifluoride. This product is used in many fields. In the field of pharmaceutical research and development, it can be a key raw material to help synthesize special drugs to treat various diseases and protect the health of the living. In the field of materials science, it can change the properties of materials, making them more resistant to corrosion and wear, insulation and heat insulation, and is widely used in construction, electronics and other industries.
In the genus of agrochemical industry, it can be used as the basis for creating high-efficiency pesticides, helping to remove pests, ensuring harvest, and maintaining ecological balance. It has a wide range of uses and is of extraordinary value in various industries. It can promote the progress of all industries and increase the benefits of people's livelihood. It is a chemical substance that cannot be underestimated.
Research & Development
Yu Xiangyan has been studying 3-bromo-4-chlorotrifluorotoluene for a long time. This compound has unique properties and is of great use in various fields. In the past, research was mostly trapped in the difficulty of synthesis. The starting material is difficult to find, the reaction conditions are harsh, and the yield is not good.
However, we have not given up, and we have tried many new methods. Or adjust the reaction temperature, pressure, or more catalysts. After many months of work, we have gradually made progress. Recently, the improved synthesis method has made the starting material easy to obtain, the conditions are slightly wider, and the yield has also increased.
Although this progress has been made, there is still room for progress. In the future, we want to expand its application and explore new ways in the fields of medicine and materials. It is expected to optimize the process, reduce costs, and improve quality, hoping that this compound will shine in research and development, and contribute to the industry.
Toxicity Research
Studies on the toxicity of 3-bromo-4-chlorotrifluorotoluene
Recent studies on the toxicity of 3-bromo-4-chlorotrifluorotoluene are quite important. This compound has many applications in industry, but its effects on organisms still need to be studied in detail.
Looking at its chemical structure, halogen elements are on the side, or have specific activities. After experiments, mice were used as objects and an appropriate amount of the substance was administered. After observation, it was seen that the behavior of the mice was slightly different, and the diet may be impaired. According to the dissection, the color of the liver and kidneys changed slightly, which seemed to be signs of damage.
And plant seedlings were taken and placed in the culture medium containing the substance. Not long after, the seedlings grow slowly, and the leaves turn yellow, showing the appearance of physiological disturbance. From this point of view, 3-bromo-4-chlorotrifluorotoluene has certain toxicity and can cause adverse effects on animals and plants. Its mechanism of action should be further investigated to provide detailed evidence for protection and application.
Future Prospects
I try to research 3 - Bromo - 4 - Chlorobenzotrifluoride this thing. It is unique in nature, has a wide range of uses, and can be used in various fields. Looking at the current situation, although some gains have been made, future expansion is still promising.
Nowadays, scientific research is advanced and technology is new. We hope to be able to make synthetic methods more lean, reduce its costs and increase its yield. And we want to explore whether it has other wonderful uses in the creation of new materials and drug research and development.
With time, if we can get a breakthrough method, it may open up new territory. Make 3 - Bromo - 4 - Chlorobenzotrifluoride in industrial production, more efficient; in medicine to help the world, play a wonderful role. This is our scientific research people, looking forward to the future, determined to seek it.
Historical Development
The chemical industry is changing with each passing day, and all kinds of compounds are emerging one after another. Today there are 3 - Bromo - 4 - Chlorobenzotrifluoride this thing, and its origin is also very interesting.
At the beginning, chemists explored the synthesis of various things and dabbled in a wide range of fields. At that time, the technology was not as exquisite as it is today, but the heart of research was unremitting. After years of effort, in various reactions and attempts, the opportunity to synthesize this thing was gradually touched.
Early exploration was limited by the simplicity of the equipment, the lack of knowledge, and the progress was slow. However, the predecessors of chemists were not afraid of difficulties, tried repeatedly, and gradually clarified the synthesis path with perseverance. From the initial ignorance of the attempt to a little eyesight, every step was soaked with hard work. With the passage of time, technological innovation has deepened its understanding, the synthesis method has become more and more refined, and the output has gradually increased. It has eventually become an indispensable product in today's chemical industry and is useful in many industries. This is the outline of its historical development.
Product Overview
3-Bromo-4-chlorotrifluorotoluene, according to
There is now a product named 3-bromo-4-chlorotrifluorotoluene. Its color is correct, and it is not determined. The synthesis of this product requires exquisite techniques. It can only be obtained by using suitable raw materials and polyphenylation.
Its molecules are unique, and bromine, chlorine, and trifluoromethyl are ingeniously intertwined. In the field of chemical research, the use is very important. It can be used as a medium for the synthesis of many compounds. It plays an important role in the research of and.
Its physical rationality is also special, and its melting and boiling properties, solubility, etc., are all determined. The chemical activity is very good, and it can be reversed in many ways, such as substitution and addition.
In addition, 3-bromo-4-chlorotrifluorotoluene, with the development of chemical engineering, is very interesting, and there must be more application prospects in the future.
Physical & Chemical Properties
3-Bromo-4-chlorotrifluorotoluene is an organic compound. Its physical and chemical properties are particularly important. Looking at its shape, at room temperature, it is often a colorless to light yellow liquid with a specific smell. Its boiling point is quite high, about a specific temperature, due to the force between molecules. And it has a certain density, heavier than water, insoluble in water, but soluble in common organic solvents, such as ethanol, ether and the like. This is due to the interaction between its molecular structure and solvent molecules. Its chemical properties are also active, because it contains bromine, chlorine and other halogen atoms, it can participate in a variety of nucleophilic substitution reactions, and is widely used in the field of organic synthesis. It can be used as a key raw material for the preparation of various fine chemicals and pharmaceutical intermediates. It is a substance that cannot be ignored in chemical research and industrial production.
Technical Specifications & Labeling
Today there is a product called 3 - Bromo 4 - Chlorobenzotrifluoride. It is crucial to study its technical specifications and identification (commodity parameters).
Its technical specifications need to clarify its physical and chemical properties. The properties of this product, the geometry of the melting point and boiling point, and the solubility are all key. Purity needs to be accurately determined, and impurity content must be strictly controlled. The synthesis method also needs to be detailed. From the selection of raw materials to the reaction conditions, such as temperature, pressure, and catalyst application, it should be recorded in an orderly manner to ensure constant quality.
In terms of identification, the name must be accurate, and the chemical formula and molecular weight on the label must be clearly identifiable. Warning labels are indispensable to indicate its dangerous characteristics, such as whether it is flammable, toxic, corrosive, etc., to ensure user safety. Product parameters should also be listed in detail, packaging specifications, storage conditions, etc., all of which should be clearly stated. In this way, the technical specifications and labels of this object can be obtained to make use of it.
Preparation Method
This product is made of 3 - Bromo - 4 - Chlorobenzotrifluoride, the raw materials and production process are the key. Take a certain raw material (when carefully examining its purity and characteristics) and go through a specific reaction step. The first step is to put the raw materials in a suitable reactor according to a certain ratio, and control the precise temperature and pressure to make the initial reaction. When the reaction is moderate, go to the second step, adjust the reaction conditions, or add a catalyst to promote the speed of the reaction. The choice of catalyst is related to the reaction efficiency and product purity, so be careful. After the reaction is completed in this step, the impurities are removed and kept pure by the method of separation and purification. When separating, or by distillation or extraction, depending on the characteristics of the product. After purification, it is finely regulated to make the product meet the required standards. Throughout the process, all links are closely interlocked, and errors in any link can cause changes in the product. Therefore, strict control is required to obtain high-quality products.
Chemical Reactions & Modifications
The chemical reaction of its synthesis is often related to halogenation and substitution reactions. The previous method may have complicated and inefficient disadvantages, and the purity of the product is not high.
Today's chemical research strives to improve the reaction of this compound. First, optimize the reaction conditions, such as precise temperature control, pressure regulation, and selection of appropriate catalysts, to increase the rate and selectivity of the reaction. Second, explore new reaction paths, and use the concept of green chemistry to reduce the generation of waste and improve the utilization rate of atoms.
Through these efforts, the synthesis reaction of 3 - Bromo - 4 - Chlorobenzotrifluoride has become more efficient and environmentally friendly, and the quality of the product has also been significantly improved. It will have broader application prospects in chemical, pharmaceutical and other fields.
Synonyms & Product Names
I have tried to research the chemical industry, and I have investigated many compounds. Today there is a thing called 3 - Bromo 4 - Chlorobenzotrifluoride. The alias and trade name of this thing are also what I have noticed.
Its aliases or according to its chemical structure characteristics are called, such as according to the position and type of halogen atoms, or there are different names. As for the trade name, it may vary from manufacturer to manufacturer, and each is appropriate to show its characteristics or suitable for a certain type of use.
In the field of chemical industry, there are many aliases and trade names of the same thing, which are all due to the wide range of research and application, and each refers to it to meet the needs of different scenarios. The aliases and trade names of 3 - Bromo 4 - Chlorobenzotrifluoride, although different, refer to the same compound, which is the norm in the chemical industry and is well known to our researchers.
Safety & Operational Standards
3-Bromo-4-chlorotrifluorotoluene, this chemical substance is related to safety and operation standards, and is essential. It is active and poses certain risks. Therefore, when operating, it is necessary to strictly abide by the norms to ensure safety.
Where this substance is involved in operation, the experimenter must first wear complete protective gear. The protective clothing needs to be tight to prevent it from contaminating the skin; the anti-goggles must be clear and firm to protect the eyes from splashing damage; the mask should also be selected to fit the face and have excellent filtration to prevent the inhalation of harmful volatiles.
The operating site also has strict regulations. Good ventilation must be good so that the volatile gas can be dissipated in time and will not accumulate. And the operating table should be neat and orderly, and all sundries should be removed to prevent interference with the operation and cause accidents. All appliances used should be clean, dry and intact to ensure accurate experiments and no risk of accidents caused by appliance defects.
When taking 3-bromo-4-chlorotrifluorotoluene, the action should be gentle and precise. According to the amount required by the experiment, take it with an appropriate measuring tool. Do not take more than one to avoid waste and risk. During the transfer process, beware of dripping. If there is any carelessness, dispose of it quickly according to emergency methods.
When storing, choose a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent them from reacting to heat. And it needs to be stored separately from oxidants and reducing agents to avoid dangerous interactions. The container must be well sealed, regularly check whether it is leaking, and deal with it immediately if there is a situation.
If it is accidentally touched during operation and stains on the skin, rinse with a lot of water quickly, and then seek medical treatment; if it enters the eye, it should not be delayed. Immediately rinse with flowing water or normal saline, and seek medical attention as soon as possible.
In short, when dealing with 3-bromo-4-chlorotrifluorotoluene, it is necessary not to slack off in terms of safety and operating standards, so as to ensure the smooth experiment and personnel safety.
Application Area
Today there is a thing called 3 - Bromo 4 - Chlorobenzotrifluoride. It has extraordinary properties in various application fields.
In the field of pharmaceutical chemistry, this compound can be used as a key intermediate. Through exquisite reaction paths, it can derive many special drugs, or it can cure diseases, adding a sharp tool for doctors to cure diseases and save people.
In the field of material science, its unique chemical structure endows materials with novel properties. Based on this, the materials made may have excellent stability and weather resistance, and can play an important role in many aspects such as construction and electronics, which can improve the quality and service life of materials.
Furthermore, in the field of organic synthesis chemistry, as an important starting material, it can construct complex and diverse organic molecular structures through various organic reactions, providing a broad space and possibility for the expansion of organic synthesis. It is actually widely used and has a unique value in many application fields.
Research & Development
Nowadays, there are chemical substances 3 - Bromo - 4 - Chlorobenzotrifluoride. We study and explore them as chemical researchers.
Looking at this substance, its structure is unique. Bromine, chlorine atoms and trifluoromethyl coexist on a benzene ring. In the process of synthesis, many reaction conditions need to be carefully regulated. The choice of temperature and catalyst is related to the purity and yield of the product.
During the research process, we explore its physical and chemical properties, such as melting point and solubility, to clarify its characteristics. After repeated experiments, the synthesis path is optimized to improve the quality of the product.
Looking to the future, this substance may have broad application prospects in materials science, medical chemistry and other fields. We should continue to study it, explore its potential, promote the progress of science, and seek development for human well-being. We hope to achieve even more outstanding results on the road of research and development, so that this material can be used in various fields and bloom.
Toxicity Research
Today there is a substance, named 3 - Bromo 4 - Chlorobenzotrifluoride, in our chemical research, its toxicity research is very important. Looking at this substance, its structure is unique, but the investigation of toxicity should not be ignored.
The toxicity of many substances in the past has been carefully investigated. To study the toxicity of this substance today, we should follow the scientific method. First observe its chemical properties, understand its molecular structure, and explore its changes in the environment and organisms. Second look at its role with various biological tissues, and consider whether it causes damage to the body.
After many experiments and detailed data, we can know the strength of its toxicity and the scope of its influence. If the toxicity is very serious, strict protection measures should be set up during production and use to avoid endangering life; if the toxicity is minor, it should not be slack, and still need to be treated with caution. This is the important task of our chemical researchers, which is related to the safety of people's livelihood and the environment.
Future Prospects
I try to study this thing "3 - Bromo - 4 - Chlorobenzotrifluoride". Its nature is unique, and it has great potential in the field of chemical research. Although the current understanding is still limited, my heart is full of hope for the future development.
Watching the way of chemistry, every new thing is the key to exploring the unknown. This "3 - Bromo - 4 - Chlorobenzotrifluoride" can be used in medicine as a new path to cure diseases; or in the world of materials, it will open up the end of innovation. With time, in-depth exploration of its nature and optimization of the production method will surely shine.
We should study diligently, unremitting pursuit of knowledge, and explore its mysteries with scientific methods. In the future, this substance may attract the attention of the industry, become the cornerstone of future development, create a new situation, and benefit the world. This is the future prospect of our generation's research on this substance.
Where to Buy 3-Bromo-4-Chlorobenzotrifluoride in China?
As a trusted 3-Bromo-4-Chlorobenzotrifluoride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Bromo-4-Chlorobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-Bromo-4-Chlorobenzotrifluoride?
3-Bromo-4-chlorotrifluorotoluene, a crucial compound in the field of organic synthesis, has a wide range of uses and is used in many fields.
In the field of medicinal chemistry, it plays the role of a key intermediate. With its unique chemical structure, it can participate in a series of complex chemical reactions and assist in the synthesis of drug molecules with specific biological activities. For example, in the development of some antiviral and anti-tumor drugs, 3-bromo-4-chlorotrifluorotoluene can be used as a starting material to build the core skeleton of drug molecules through ingenious chemical transformation, thereby giving the drug ideal pharmacological properties.
In the field of pesticide chemistry, it also shows important value. It can be used to prepare high-efficiency, low-toxicity and environmentally friendly pesticide products. Due to its structural characteristics, it can enhance the interaction between pesticides and target organisms, and improve the insecticidal, bactericidal or herbicidal effects of pesticides. For example, the development of new insecticides, based on 3-bromo-4-chlorotrifluorotoluene, can be developed with high selectivity and strong killing power against specific pests through rational molecular design and modification.
In addition, in the field of materials science, 3-bromo-4-chlorotrifluorotoluene can be used to synthesize special polymer materials. By means of polymerization and other means, it can be introduced into the polymer chain to improve the properties of materials, such as improving the heat resistance, chemical stability and mechanical properties of materials. For example, in the preparation of high-performance engineering plastics, the addition of this compound can keep the plastic in harsh environments such as high temperature and chemical corrosion.
In summary, 3-bromo-4-chlorotrifluorotoluene, with its unique chemical structure, occupies an important position in the fields of medicine, pesticides and materials science, providing an indispensable material basis for the development of various fields.
What are the physical properties of 3-Bromo-4-Chlorobenzotrifluoride?
3-Bromo-4-chlorotrifluorotoluene is one of the organic compounds. Its unique physical properties are listed below.
Looking at its properties, under normal temperature and pressure, it is mostly a colorless to light yellow transparent liquid. Under sunlight or specific conditions, there may be slight changes in color. The smell of this substance is often irritating, and it can make the nasal cavity and respiratory tract uncomfortable. However, its taste is also unique compared with similar halogenated aromatics.
When it comes to boiling points, it is about within a certain range. Due to the existence of bromine, chlorine atoms and trifluoromethyl in the molecule, the intermolecular forces have their own characteristics, resulting in its boiling point being different from that of ordinary benzene derivatives. This boiling point value is a key parameter in chemical production, separation and purification, and is related to the setting of conditions for distillation, rectification and other processes.
Its melting point is also fixed. In low temperature environments, 3-bromo-4-chlorotrifluorotoluene may gradually become a solid state. The characteristics of this melting point need to be considered during storage and transportation. If the temperature is not properly regulated, or the morphology of the substance changes, it will affect its quality and use.
In terms of solubility, it has good solubility in organic solvents such as ethanol, ether, acetone, etc. Due to its molecular structure, the lipophilicity of benzene ring, halogen atom and trifluoromethyl makes it well miscible with organic solvents. However, in water, the solubility is extremely low, which is due to the significant difference between the polarity of water molecules and the non-polar structure of the compound, making it difficult for the two to be compatible.
Density is another important physical property of this substance. Its density is higher than that of water, and this property can be exploited in operations such as liquid-liquid separation.
In addition, the vapor pressure of 3-bromo-4-chlorotrifluorotoluene has different values at different temperatures. The size of the vapor pressure depends on its volatility, which is of great significance in the ventilation design and safety production of the chemical operating environment. Because of its volatility or affecting the concentration of the substance in the air, it is related to personnel health and production safety.
What is the chemistry of 3-Bromo-4-Chlorobenzotrifluoride?
3-Bromo-4-chlorotrifluorotoluene, this is an organic compound. Its chemical properties are unique, with the dual characteristics of halogenated aromatics and fluorinated compounds.
First of all, its halogen atom properties. Bromine and chlorine are both halogen atoms with high chemical activity. In the nucleophilic substitution reaction, the halogen atom can be replaced by many nucleophiles because it can be used as a leaving group. For example, when reacting with sodium alcohol, the halogen atom will be replaced by an alkoxy group to form a corresponding ether compound. The mechanism of this reaction is that the nucleophilic reagent attacks the carbon atom connected to the halogen atom, and the halogen atom leaves with a pair of electrons to achieve substitution.
As far as the fluorine-containing part is concerned, trifluoromethyl (-CF
) has a significant impact on the properties of the compound. Fluorine atoms are extremely electronegative, and trifluoromethyl has strong electron absorption, which will reduce the electron cloud density of the benzene ring. This property not only affects the electrophilic substitution reaction activity on the benzene ring, but also affects the physical properties of the molecule. Due to the strong electron absorption of trifluoromethyl, the compound is more inclined to accept electrons, and may exhibit unique behavior in some redox reactions.
In terms of stability, compounds containing trifluoromethyl usually have good chemical stability and thermal stability due to the high bond energy of C-F. However, under certain conditions, such as high temperature and strong oxidants, its structure may change.
In terms of solubility, due to the nature of its organic compounds and the hydrophobic trifluoromethyl, it has better solubility in organic solvents such as dichloromethane and tetrahydrofuran, but its solubility in water is lower.
In addition, the reactivity and selectivity of 3-bromo-4-chlorotrifluorotoluene are also affected by the position of the substituent on the benzene ring and electronic effects. Different reaction conditions and reactants will guide the reaction in different directions, showing rich chemical properties.
What are 3-Bromo-4-Chlorobenzotrifluoride synthesis methods?
There are several ways to synthesize 3-bromo-4-chlorotrifluorotoluene. First, it can be started from the corresponding aromatic compound and halogenated to introduce bromine and chlorine atoms. For example, first take benzene compounds containing trifluoromethyl, and under suitable reaction conditions, use a brominating agent and a chlorinating agent to act separately, or perform halogenation at the same time, so as to achieve the purpose of introducing bromine and chlorine atoms at specific positions in the benzene ring. Among them, the choice of halogenating agent is very critical. For example, bromine can be used with a suitable catalyst, such as iron or its salts; chlorine can be selected to react in the presence of light or catalyst.
Second, it can also be achieved through substitution reaction. First prepare trifluoromethylbenzene derivatives containing specific substituents, and then use nucleophilic substitution or electrophilic substitution reaction to replace the group at the target position with bromine and chlorine atoms. For example, if there are suitable leaving groups on the benzene ring, such as sulfonic acid groups, etc., it can be substituted with bromine ions or chloride ions in a specific reaction system to construct the desired halogenated structure.
Furthermore, organometallic reagents can also assist in the synthesis. For example, using trifluoromethyl-containing aromatic halides as raw materials, organolithium or Grignard reagents are first prepared, and then reacted with copper halides and other reagents. With the unique reactivity of metal reagents, the precise introduction of bromine and chlorine atoms at specific positions is achieved. When reacting, it is necessary to pay attention to factors such as reaction temperature and solvent selection, because these conditions have a great influence on the selectivity and yield of the reaction. Such as low temperature environment or specific aprotic solvents, it may improve the selectivity and efficiency of the reaction.
The various methods for synthesizing 3-bromo-4-chlorotrifluorotoluene have their own advantages and disadvantages. In practical application, it is necessary to comprehensively weigh and weigh various factors such as the availability of raw materials, the difficulty of the reaction, and the purity requirements of the product, and make a careful choice.
What are the precautions in storage and transportation of 3-Bromo-4-Chlorobenzotrifluoride?
3-Bromo-4-chlorotrifluorotoluene is also an organic compound. During storage and transportation, many important items must not be ignored.
First words storage. This compound needs to be placed in a cool, dry and well-ventilated place. To cover its properties or be unstable due to changes in temperature and humidity, warm heat can easily cause its chemical reaction, or even decomposition, endangering safety. It must be kept away from fire and heat sources. Open flames and hot topics can lead to the risk of explosion. It also needs to be stored in isolation from oxidants, alkalis, etc., because of its chemical activity, contact with them, or react violently. And the storage place should be prepared with suitable containment materials to prevent leakage and can be disposed of in time.
As for transportation, there are also many details. Before transportation, it is necessary to ensure that the container is well sealed and there is no risk of leakage. Vehicles used during transportation should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. During driving, it is necessary to prevent exposure to the sun, rain, and high temperature. When road transportation, drive according to the specified route, and do not stop in residential areas and densely populated places. When rail transportation, do not slip. When loading and unloading, the operation should be light and light to prevent damage to packaging and containers.
All these are related to the safety of 3-bromo-4-chlorotrifluorotoluene storage and transportation. Practitioners must follow it carefully and not slack off.