3-Aminobenzotrifluoride

Duxiu Chemical

Specifications

HS Code	359998
Chemical Formula	C7H6F3N
Molecular Weight	161.12
Appearance	Colorless to light yellow liquid
Odor	Characteristic odor
Melting Point	-22°C
Boiling Point	202 - 204°C
Density	1.287 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents
Flash Point	88°C
Vapor Pressure	Low
Stability	Stable under normal conditions
Hazardous Nature	Harmful if swallowed, inhaled or in contact with skin

As an accredited 3-Aminobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 3 - Aminobenzotrifluoride packaged in air - tight, corrosion - resistant containers.
Storage	3 - Aminobenzotrifluoride should be stored in a cool, dry, and well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in tightly - sealed containers to prevent vapor leakage. Avoid storage near incompatible substances. This helps maintain its stability and reduces risks associated with potential reactions or degradation.
Shipping	3 - Aminobenzotrifluoride is shipped in accordance with strict chemical transportation regulations. Packed in well - sealed, corrosion - resistant containers, it is transported by specialized carriers to ensure safe and proper handling during transit.

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General Information

Historical Development

3-Aminotrifluorotoluene is also an organic compound. The origin of its substance can be traced back to the process of chemical research in the past. At the beginning, Zhu Xian Da diligently explored the field of organic synthesis, hoping to obtain this special product with new techniques.
At that time, limited by skills and cognition, the road to synthesis was full of thorns. However, the heart of a scholar is determined, and he has tried and failed again and again. After years of research, he gradually obtained the method of synthesis. The initial yield is still low, and the quality is not up to par.
After years of delay, technology has advanced day by day, and various instruments have been improved, and the method of synthesis has become more and more exquisite. Chemists study the reaction conditions and the ratio of raw materials carefully, so that the yield of 3-aminotrifluorotoluene gradually increases, and the quality is better. Its use in various fields such as medicine and materials has also increased with its development, adding a bright pearl to the current chemical industry.

Product Overview

"About 3-Aminotrifluorotoluene"
3-Aminotrifluorotoluene is a valuable compound in the chemical industry. Its appearance is colorless to light yellow liquid and has a special odor. In the field of organic synthesis, this product has a wide range of uses and is often a key intermediate.
In terms of its chemical properties, it has unique chemical activity due to the presence of amino groups and trifluoromethyl groups. Amino groups can participate in a variety of nucleophilic reactions, while trifluoromethyl groups endow it with special physical and chemical properties, such as enhancing the stability of compounds and changing polarity.
In the preparation process, after many studies, several mature methods have been developed. Or made from specific aromatics through nitrification, reduction and other steps. Each method has its own advantages and disadvantages and needs to be selected according to actual needs.
Because of its potential applications in medicine, pesticides, materials and other industries, it has attracted much attention in the industry. With the advance of science and technology, its application prospects are expected to be broader, and it will definitely contribute to the development of related fields.

Physical & Chemical Properties

"On the Physical Properties of 3-Aminotrifluorotoluene"
3-Aminotrifluorotoluene has unique physical properties. Looking at its state, at room temperature, it is often colorless to light yellow liquid, like a clear spring, clear and fluid. Observe its taste, emit a special smell, slightly diffuse in the air, and the recognition is quite high.
In terms of its chemical properties, there are also considerable points. This substance has certain chemical activity and can combine with many reagents under specific conditions. In case of some strong oxidants, or a violent reaction, just like dry wood meets fire, it can produce different products. And because of its fluorine-containing group, it gives it unique stability, and it can still retain its own structure in some harsh chemical environments, just like a rock that resists wind and rain erosion. Such physical properties make it have extraordinary application value in many fields of chemical industry, and it is one of the important objects of chemical research.

Technical Specifications & Labeling

3-Aminotrifluorotoluene, its process specifications and identification (product parameters) are the key. The preparation of this product requires a specific method. The ratio of materials and reaction conditions are fixed. The reaction temperature should be controlled in a certain range, and the duration must also be accurate. The appearance of the product should be suitable for a specific shape, and the color and luster are also required. The purity needs to reach a high level, and the impurity content must be low. These are all elements to ensure product quality. The label should clearly state the composition, characteristics, hazard warnings, etc. In this way, this product can be properly applied in various fields of chemical industry, play its due effect, and ensure safety.

Preparation Method

The method of making 3-aminotrifluorotoluene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials are often taken from a certain type of fluoroaromatic hydrocarbon and treated with a specific chemical treatment to achieve the purpose of conversion. In the production process, the raw materials are first placed in a special reactor, controlled at a suitable temperature and pressure, and a specific catalyst is added to promote the reaction. At the beginning of the reaction step, the chemical bonds of the raw material molecules are gradually opened under the action of the catalyst, and they collide with each other to form an intermediate product. After a series of reactions, it is gradually converted into the target product 3-aminotrifluorotoluene. The catalytic mechanism is that the catalyst used can reduce the activation energy of the reaction, make the reaction more likely to occur, and improve the reaction rate and product purity. In this way, 3-aminotrifluorotoluene was prepared through various steps.

Chemical Reactions & Modifications

3-Aminotrifluorotoluene, its chemical reaction and modification are quite critical. In the past, the preparation of this compound, the reaction conditions were harsh, and the yield was not ideal. Such as the common reaction of specific halogenated aromatics with fluorine-containing reagents and amination reagents, although products can be formed, but the side reactions are complicated, separation and purification are difficult, and the requirements for reaction equipment are very high.
Today, chemists are committed to improving. Or optimize the reaction catalyst, with new high-efficiency catalysts, make the reaction conditions mild, accelerate the reaction process, and improve the yield. Or innovate the reaction path to avoid the drawbacks of the traditional route. For example, adopt the concept of green chemistry to reduce the use of harmful reagents and reduce environmental pollution. After many improvements, the synthesis process of 3-aminotrifluorotoluene has been perfected day by day, laying a solid foundation for its wide application in materials, medicine and other fields.

Synonyms & Product Names

3-Aminotrifluorotoluene, this substance is widely used in the chemical industry. There are also many other names, such as m-aminotrifluorotoluene. In commerce, the trade names given by different manufacturers are also different.
The research on this substance has a long history. In the past, scholars studied its properties and preparation methods in order to expand its application. In industrial production, in order to obtain high-purity 3-aminotrifluorotoluene, craftsmen continue to improve the process.
Looking at its trade name, although it is different from the scientific name, it all refers to this substance. Either to highlight its characteristics, or due to market strategies, the trade names are diverse. However, regardless of the scientific name or the name of the product, it is all used to identify this chemical product, enabling researchers, producers, and users to understand its meaning, communicate freely in related fields, and promote the development and application of 3-aminotrifluorotoluene.

Safety & Operational Standards

Specifications for safety and operation of 3-aminotrifluorotoluene
Fu 3-aminotrifluorotoluene is an important raw material in the chemical industry. Its preparation and application are related to the rise and fall of the industry and the essence of safety. Therefore, this specification is established to ensure that everything goes smoothly and personnel are safe.
When preparing, the raw materials must be selected to be pure, and all kinds of impurities can cause abnormal reactions and accidental changes. The reaction apparatus must be sturdy and tight to prevent leakage. During the reaction process, the control of temperature and pressure is the key. If it is slightly abnormal, there may be the risk of explosion and fire.
Operating place, ventilation must be smooth, and exhaust gas should not accumulate, so as not to poison people. Operators, in front of protective gear, clothing, hats, gloves, masks, everything is available to protect their skin and breathing.
When storing, choose a cool and dry place to avoid fire and heat, away from oxidants and acids, to prevent interaction and unexpected disasters. The container is tightly sealed and clearly marked, so that people can know its nature at a glance.
When handling, lift and place it gently, do not collide, and prevent the container from being damaged. If there is a leak, start an emergency case immediately. Small leaks should be adsorbed with sand, vermiculite and other substances and disposed of properly. Large leaks should be evacuated, and fire and electricity should be banned. Professionals should clean it up in an appropriate way.
This norm is gathered by the experience of predecessors, and it is also a lesson from blood and tears. Everyone should keep it in mind, practice it, ensure the safety of production, and protect the well-being of themselves and others. This is the heavy responsibility of chemical practitioners.

Application Area

"3-Aminotrifluorotoluene application field"
3-Aminotrifluorotoluene has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to synthesize many specific drugs, or for difficult diseases, it has the power of relieving and healing. In the field of materials science, it can contribute to the creation of new materials, making the materials have specific properties, such as extraordinary stability and corrosion resistance. Also emerging in the field of pesticides, assisting in the research of high-efficiency and low-toxicity pesticides, protecting crops from pests and diseases, and ensuring a bumper harvest. With its unique chemical properties, this substance shines brightly in many fields, injecting vigorous impetus into the development of various industries. It is an important chemical material with a wide range of uses.

Research & Development

The industry of chemical industry is changing with each passing day, and the research of materials is related to people's livelihood and national transportation. Today there are 3-Aminobenzotrifluoride of this product, its unique nature and wide range of uses.
We have been researching it for years. At the beginning, we analyzed its structure and explored its properties. We encountered many difficulties, but we did not dare to slack off. After repeated experiments, its characteristics were finally revealed.
It can be used as a key intermediate in pharmaceutical synthesis to help the research and development of new drugs, and it is expected to solve the pain of disease. In the field of materials, it can also add unique properties to make materials better.
Although we have gained something, the road ahead is still long. We should continue to study, seek better methods, improve its yield and reduce its cost. Expected to be widely promoted in the world, for the prosperity of the chemical industry and the prosperity of people's livelihood, we have exhausted our efforts and moved forward unremittingly.

Toxicity Research

This study 3 - Aminobenzotrifluoride the toxicity of this substance. It is a chemical product, which is crucial for toxicity research. Looking at all the chemicals in the past, the toxicity is unknown and causes many disasters, so this substance should not be ignored.
Detailed observation of its structure, fluorine-containing groups or affect its toxicity performance. After many experiments, explore its effect on organisms. Take small animals as samples and observe the symptoms after ingestion or exposure. It may affect the physiological functions of animals and cause discomfort to the body.
Also consider its behavior in the environment, in water, soil and other media, or have different reactions, which in turn affect the surrounding ecology. Although the experiment has initial results, the toxicity study still needs to be in-depth to clarify the exact degree of harm, so as to provide a solid basis for future use and protection, so as to avoid the mistakes of predecessors and ensure safety.

Future Prospects

There is now a name for 3-aminotrifluorotoluene, which has great potential in the field of chemical industry. Although the current state of view has been explored, there is still a vast space for development.
One of the future prospects is that in terms of synthesis technology, it is expected to achieve a more refined state, making the yield jump and the cost drop, so as to increase its competitiveness in the market. Second, its application scope will also be expanded. It may emerge in the field of pharmaceutical creation and contribute to the treatment of various diseases; or in the field of material research and development, give birth to novel functional materials.
Our chemical researchers, with an enterprising heart and unremitting research, hope to make 3-aminotrifluorotoluene bloom in the future, for the prosperity of the chemical industry, for the well-being of the world, and do our best to open up the unprecedented territory to meet the brilliant future.

Where to Buy 3-Aminobenzotrifluoride in China?

As a trusted 3-Aminobenzotrifluoride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 3-Aminobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-Aminobenzotrifluoride?

3-Aminotrifluorotoluene is an important raw material for organic synthesis and is widely used in many fields such as medicine, pesticides, and dyes.
In the field of medicine, it can be used as a key intermediate to synthesize a variety of drugs. For example, many drugs for the treatment of nervous system diseases need to use 3-aminotrifluorotoluene to build a specific chemical structure during the synthesis process, which in turn endows the drug with unique physiological activity, which is beneficial for relieving symptoms and treating diseases.
In terms of pesticides, high-efficiency, low-toxicity and environmentally friendly pesticides can be prepared from this raw material. Such pesticides have good control effects on pests and diseases, which can not only ensure crop yield and quality, but also reduce environmental pollution and impact on non-target organisms.
In the dye industry, 3-aminotrifluorotoluene is also indispensable. With it, bright-colored, light-resistant and washable dyes can be synthesized, which are widely used in textile, printing and dyeing industries to make fabrics show rich and diverse colors, enhance product aesthetics and added value.
In short, 3-aminotrifluorotoluene occupies a key position in many industries due to its unique chemical properties and plays an important role in promoting the development of related fields.

What are the physical properties of 3-Aminobenzotrifluoride?

3-Aminotrifluorotoluene, its physical properties are as follows:
This substance is mostly colorless to light yellow liquid at room temperature, and it looks translucent and clear. Smell it, it has a special smell, but this smell is not pungent and intolerable, but it is also clearly identifiable.
Its melting point is quite low, about -18 ° C, so it can still maintain a liquid state under common low temperature environments. The boiling point is relatively high, in the range of 222-224 ° C. This boiling point characteristic makes it difficult to quickly vaporize and escape under normal heating conditions, and the stability is good.
In terms of density, it is about 1.328g/cm ³, which is heavier than water. If mixed with water, it will sink underwater. In organic solvents, such as ethanol, ether, etc., it exhibits good solubility and can be miscible with it to form a uniform and stable solution. However, in water, the solubility is extremely low and almost insoluble, because it is quite different from water in polarity.
The vapor pressure of 3-aminotrifluorotoluene is relatively small at room temperature, and it is not easy to evaporate into the air in large quantities. And its flash point is 96 ° C. In case of open flame, hot topic, etc., there is a risk of combustion. When using and storing, pay attention to fire safety. Its refractive index is about 1.522-1.524. When light passes through, a specific refraction phenomenon will occur. This property may have applications in optical correlation detection and analysis.

What is the chemistry of 3-Aminobenzotrifluoride?

3-Aminotrifluorotoluene, which is an organic compound, has unique chemical properties.
This substance is often colorless to light yellow liquid in appearance and has a special odor. Its chemical properties are active, because it contains two important functional groups: amino groups and trifluoromethyl groups.
The presence of amino groups gives it alkalinity and can react with acids to form corresponding salts. In case of hydrochloric acid, hydrochloric salts will be formed. And amino groups can participate in a variety of nucleophilic substitution reactions. When reacting with halogenated hydrocarbons, the nitrogen atoms in the amino group will attack the carbon atoms of halogenated hydrocarbons, and the halogen atoms will leave to form new carbon-nitrogen bonds, resulting in nitrogen-containing derivatives.
trifluoromethyl is a strong electron-absorbing group, which significantly affects the electron cloud distribution of the molecule and increases the molecular polarity. Due to the strong electron-absorbing properties of trifluoromethyl, the chemical stability of the substance is improved, and the thermal stability is also better than that of many similar compounds without this group. And the existence of trifluoromethyl changes the electron cloud density distribution on the benzene ring, which affects the activity and selectivity of electrophilic substitution reactions on the benzene ring, usually making the reaction more likely to occur in the para-position of amino groups. In addition, 3-aminotrifluorotoluene has good solubility in organic solvents and is soluble in common organic solvents such as ethanol, ether, and dichloromethane, which is conducive to its use as a reactant or intermediate in organic synthesis reactions. It has important applications in drug synthesis, materials science, and many other fields.

What are 3-Aminobenzotrifluoride synthesis methods?

There are several common methods for the synthesis of 3-aminotrifluorotoluene.
One is to use 3-nitrotrifluorotoluene as the starting material and obtain it by reduction reaction. This reduction method can be achieved by catalytic hydrogenation. In the presence of appropriate catalysts, such as palladium carbon (Pd/C) or Raney Ni, hydrogen is introduced, and the nitro group can be gradually reduced to amino groups under suitable temperature and pressure conditions. This process requires fine regulation of the reaction conditions. If the temperature is too high or the pressure is too high, side reactions such as excessive reduction may occur, which will affect the purity and yield of the product. For example, the reaction temperature may be controlled between 50-100 ° C and the pressure is about 1-5 MPa, which can be fine-tuned according to the actual reaction conditions.
Second, 3-nitrotrifluorotoluene can also be reduced by chemical reducing agents. Common chemical reducing agents such as iron-hydrochloric acid system. 3-nitrotrifluorotoluene is placed in a solution containing hydrochloric acid, and iron powder is used as the reducing agent to slowly react. In this reaction, iron interacts with hydrochloric acid to produce new hydrogen, which in turn reduces the nitro group. However, this method of post-treatment is slightly more complicated, because by-products such as iron salts are produced, and multiple steps such as filtration, extraction, and washing are required to purify the product.
In addition, suitable aryl halides can be prepared by nucleophilic substitution reaction. First select an aryl halide containing trifluoromethyl, and ammonia or amine compounds, and carry out nucleophilic substitution in the presence of appropriate bases and catalysts. The base can be potassium carbonate, sodium carbonate, etc., and the catalyst can be copper salts, such as cuprous iodide (CuI). The reaction is carried out in suitable organic solvents, such as N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), etc. These solvents have good solubility to the reaction substrate and reagent, which is conducive to the reaction. The reaction temperature may be 80-150 ° C, depending on the specific substrate and reaction process.
There are also those prepared by diazotization-reduction method. First, aniline compounds containing trifluoromethyl are diazotized to obtain diazonium salts, and then the diazonium group is reduced to hydrogen with suitable reducing agents, such as hypophosphoric acid (H < PO >), and amino groups are introduced. This method needs to pay attention to the control of the conditions of the diazotization reaction. The temperature usually needs to be kept at a low temperature, such as 0-5 ° C, to prevent the decomposition of diazonium salts and affect the subsequent reaction and product quality.

3-Aminobenzotrifluoride what are the precautions during use

3-Aminotrifluorotoluene is a commonly used raw material in organic synthesis. It is widely used. When using it, you must pay attention to many matters.
The first priority is safety. This substance is toxic and irritating, and can cause physical discomfort when it touches the skin, eyes, or inhalation or ingestion. Therefore, when operating, it is necessary to wear suitable protective equipment, such as protective gloves, goggles, gas masks, etc., to avoid direct contact. And the operation should be done in a well-ventilated place to prevent the accumulation of steam and the risk of poisoning.
The second is related to storage. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its flammability, it can burn and explode in case of open flames and hot topics, so there must be no fire source in the storage. It also needs to be stored separately from oxidants, acids, etc., and should not be mixed with storage to prevent dangerous chemical reactions.
Furthermore, in the process of use, it is crucial to accurately control the dosage. Because it is an organic synthetic raw material, the dosage is directly related to the reaction effect and product purity. Therefore, it must be calculated carefully before use, and it must be accurately measured according to the needs of experiment or production.
In addition, after use, proper disposal of the residue should not be underestimated. Do not dump it at will, and it needs to be treated harmlessly in accordance with relevant regulations to avoid polluting the environment.
In short, with 3-aminotrifluorotoluene, safety is the top priority, and all links should be handled with caution, so as to ensure the smooth use process, protect people, and protect the environment.