3 Amino 4 Nitrobenzitrifluoride
Fluoride
3-Amino-4-nitrobenzitrifluoride
Chemical Formula C7H3F3N2O2
Molecular Weight 204.106
Appearance Yellow to orange solid
Melting Point 76 - 80 °C
Boiling Point 257.3 °C at 760 mmHg
Density 1.476 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
Flash Point 109.4 °C
Vapor Pressure 0.0116 mmHg at 25 °C
FAQ

What are the main uses of 3-Amino-4-nitrobenzitrifluoride?

3-Amino-4-nitrotrifluorotoluene is a crucial compound in the field of organic synthesis. Its main uses cover the following ends.

First, it plays a great role in the synthesis of medicine. It is often a key intermediate for the synthesis of specific drugs. Due to its unique molecular structure, it has some special chemical properties and can participate in many reactions, thus constructing a drug molecular structure with specific biological activities. For example, it can be combined with other compounds through a specific reaction path to generate drugs with therapeutic effects on specific diseases. For example, drug development for certain inflammatory diseases and neurological diseases may use it as a starting material and produce the desired active ingredient through multi-step reactions.

Second, in the field of pesticides, it also plays an important role. It can be used as an important cornerstone for the synthesis of new pesticides. With its chemical properties, the synthesized pesticides may have many advantages such as high efficiency, low toxicity, and environmental friendliness. For example, through a series of reactions, insecticides with strong targeted killing effects on specific pests or fungicides with good control effects on certain plant diseases can be prepared to help agricultural production and improve crop yield and quality.

Third, it also has applications in materials science. It can be used to prepare materials with special properties. For example, it is introduced into the synthesis process of polymer materials, so that the resulting materials have unique electrical, optical or thermal properties. The synthesized polymer materials may have good heat resistance and corrosion resistance, and have potential application value in high-end fields such as aerospace, electronics and electrical appliances.

Fourth, it also has a place in the dye industry. Because the molecular structure can be modified to show different color characteristics, it can be used as a raw material for synthesizing new dyes. Synthetic dyes may have the advantages of bright color, high light fastness, and strong chemical stability. They are widely used in textile, printing and dyeing industries, giving fabrics rich color and long-lasting color fastness.

What are the physical and chemical properties of 3-Amino-4-nitrobenzitrifluoride

3-Amino-4-nitrotrifluorotoluene, an organic compound, has unique physical and chemical properties and is related to many chemical uses, so the details are as follows:

Under normal temperature and pressure, it is usually a light yellow to brown solid. Due to the specific chromophore group in the molecular structure, it exhibits this color state. And the substance has a unique smell, although it is not strong and pungent, it can be distinguished by a fine smell.

When the melting point is discussed, it is about 45-49 ° C. When the temperature reaches this range, the intermolecular force changes, and the substance gradually melts from a solid state to a liquid state. This melting point characteristic is crucial in the separation, purification and molding of compounds, and can be used to select suitable temperature conditions to achieve specific process goals.

In terms of boiling point, it is about 277 ° C. At this temperature, the compound is violently converted from liquid to gaseous state, and the molecule obtains enough energy to break free from the liquid phase. This boiling point value is an important parameter in separation technologies such as distillation, which can help separate the compound from other substances with large boiling points.

In terms of solubility, 3-amino-4-nitrotrifluorotoluene is insoluble in water. Due to its organic structure and hydrophobicity, it is difficult for water molecules to form effective interactions with it. However, it is soluble in common organic solvents such as dichloromethane, chloroform, toluene, etc. In organic solvents, molecules and solvent molecules interact with van der Waals forces, hydrogen bonds, etc., and disperse uniformly. This property is convenient for acting as a solvent for reactants or products in organic synthesis reactions, and is also conducive to extracting products from the reaction system.

In terms of stability, it is relatively stable under general conditions. However, because its structure contains nitro and amino groups, it is at risk of combustion and explosion in case of open flame, hot topic or contact with strong oxidants. Nitro is oxidizing, and amino groups can be oxidized, which can cause violent reactions under specific conditions. And it is decomposed by hot topic to release toxic gases, such as nitrogen oxides and fluorine-containing compounds, which are harmful to the environment and human health.

In summary, the physicochemical properties of 3-amino-4-nitrotrifluorotoluene determine that its application in the chemical industry requires careful operation, full consideration of its characteristics, and production safety and efficiency.

What is 3-Amino-4-nitrobenzitrifluoride production method?

The preparation method of 3-amino-4-nitrotrifluorotoluene is the method of the past, and the following steps are followed.

First, with appropriate starting materials, compounds containing benzene rings are often selected. For example, take toluene derivatives first and nitrate them. This reaction is quite critical and requires fine regulation of the reaction conditions. In a suitable reaction vessel, add toluene derivatives, and use mixed acids such as sulfuric acid and nitric acid as nitrifiers to control factors such as temperature and reaction time. If the temperature is too high, side reactions will increase, which will affect the purity of the product; if the temperature is too low, the reaction rate will be slow and take a long time. After this nitrification reaction, nitro groups can be introduced at specific positions in the benzene ring to obtain nitro-containing toluene derivatives.

Second, the amination reaction is carried out on the obtained nitrotoluene derivatives. This process also requires careful operation, and suitable amination reagents are often selected, such as ammonia gas and catalyst. The choice of catalyst is very important, and its activity and selectivity are related to the efficiency of the reaction and the yield of the product. In a specific reaction environment, such as in an autoclave, adjust the pressure, temperature and other conditions, so that the amino group can successfully replace the group at the appropriate position on the benzene ring, and then obtain 3-amino-4-nitrotrifluorotoluene.

However, this ancient method may have many shortcomings. For example, in the nitrification reaction, the use of mixed acid seriously corrodes the equipment, and produces a large amount of waste acid, which is complicated to deal with, which does not conform to the current concept of environmental protection. During the amination reaction, the recovery and repurposing of the catalyst is also a major problem, resulting in high production costs. Therefore, the current production method is often improved, and strive for better methods to solve the difficulties of the past production method.

What are the precautions in storage and transportation of 3-Amino-4-nitrobenzitrifluoride?

3-Amino-4-nitrotrifluorotoluene is one of the chemical substances. When storing and transporting, pay attention to many matters.

When storing, choose the first environment. It must be placed in a cool, dry and well-ventilated place, away from fires and heat sources. The cover may cause danger, such as combustion or even explosion, due to the heat or open flame of the substance. The temperature of the warehouse should be controlled within an appropriate range, not too high, to prevent its chemical properties from changing.

Furthermore, the storage place should be stored separately from oxidants, acids, bases, etc., and must not be mixed. This is because it is easy to chemically react with such substances, or cause adverse consequences. And the storage area should be equipped with suitable materials to contain the leakage, in case of accidental leakage, it can be properly handled in a timely manner.

As for transportation, it is necessary to ensure that the packaging is complete and sealed before transportation. Packaging materials need to be able to resist vibration, collision and friction to avoid package damage and material leakage during transportation. During transportation, relevant transportation regulations must be strictly adhered to, and transportation vehicles should be equipped with corresponding fire equipment and leakage emergency treatment equipment.

Escort personnel should also be familiar with the characteristics of the substance and emergency disposal methods. During driving, avoid sun exposure, rain exposure, and stay away from densely populated areas and fire and heat sources. In case of an emergency, they can respond quickly and properly according to the established emergency plan to ensure the safety of transportation.

3-Amino-4-nitrobenzitrifluoride impact on the environment and people

3-Amino-4-nitrotrifluorotoluene is a genus of organic compounds. Its impact on the environment and human body cannot be ignored.

At one end of the environment, if this compound is released into nature, it may cause multiple effects. Its chemical properties make it stable in the environment and difficult to degrade quickly. If it flows into the water body, it may harm aquatic organisms. Because of its nitro and fluorine atoms, it may interfere with the physiological process of aquatic organisms, causing growth, reproduction and even death. If it is scattered in the soil or acted by soil microorganisms, its transformation products may still be potentially harmful, and may affect soil fertility and structure, disturbing plant root growth.

As for personal effects, this compound may invade the human body by inhalation, ingestion or skin contact. As far as inhalation is concerned, its volatile gaseous substances may irritate the respiratory tract, causing cough, asthma, dyspnea, etc. Long-term exposure may damage lung function and increase the risk of respiratory diseases. If ingested, it may harm the digestive system, causing nausea, vomiting, abdominal pain and other discomfort. Skin contact may cause skin allergies, redness, swelling, itching, and in severe cases, damage the skin barrier, increasing the chance of harmful substances invading.

Furthermore, the amino and nitro groups contained in it are metabolized in the human body, or bioconverted to generate active intermediates. These intermediates may react with biological macromolecules in human cells, such as DNA and proteins, interfere with the normal physiological functions of cells, or cause gene mutations, long-term accumulation, or increase the risk of cancer and other diseases. Therefore, the use and handling of 3-amino-4-nitrotrifluorotoluene should be done with caution to prevent it from harming the environment and humans.