2 Methoxy 5 Nitrobenzotrifluoride
Fluoride

2-Methoxy-5-Nitrobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

897874

Chemical Formula C8H6F3NO3
Molar Mass 221.13 g/mol
Appearance Solid (usually)
Melting Point Data needed
Boiling Point Data needed
Density Data needed
Solubility In Water Low (expected, due to non - polar groups)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Vapor Pressure Data needed
Stability Stable under normal conditions, but reactive towards strong reducing agents and bases
Odor Data needed
Chemical Formula C8H6F3NO3
Molecular Weight 221.13
Appearance Typically a solid or liquid (specific appearance may vary)
Solubility In Water Low solubility, as it is an organic compound with non - polar fluorinated and aromatic parts
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, etc.
Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

As an accredited 2-Methoxy-5-Nitrobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 kg of 2 - Methoxy - 5 - Nitrobenzotrifluoride packaged in air - tight, corrosion - resistant containers.
Storage 2 - Methoxy - 5 - Nitrobenzotrifluoride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture and air exposure, which could potentially lead to chemical degradation. Avoid storing near incompatible substances to ensure safety.
Shipping 2 - Methoxy - 5 - Nitrobenzotrifluoride, a chemical, must be shipped in accordance with strict hazardous materials regulations. It should be properly packaged in suitable containers to prevent leakage during transit.
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2-Methoxy-5-Nitrobenzotrifluoride
General Information
Historical Development
2 Methoxy - 5 - Nitrobenzotrifluoride is a special chemical product. On the way of the development of chemistry, such compounds have been studied in detail since the beginning. In the past, chemical research was still unknown, and many substances were unknown. However, with the deepening of the study of wise men and the advancement of analytical technology, 2 Methoxy - 5 - Nitrobenzotrifluoride has entered the field of vision. Early or only a brief observation of its appearance, after repeated tests, its structure and properties were analyzed. Scientists in the laboratory, with perseverance, study day and night, striving to clarify its characteristics and uses. With the passage of time, the understanding of it continues to expand, the application field is also gradually broadening, in the chemical industry, medicine and many other aspects, gradually showing important value, and contributing a lot to the progress of mankind.
Product Overview
2-Methoxy-5-nitrotrifluorotoluene is a crucial chemical in the field of organic synthesis. Its properties are light yellow to yellow liquid, with specific chemical properties and physical properties. In many fields of the chemical industry, this product has a wide range of uses.
From a synthetic point of view, the preparation of this chemical requires a specific chemical reaction process. With related organic raw materials, high purity products can be obtained by carefully controlling the reaction conditions, such as temperature, pressure, catalyst, etc. The presence of methoxy, nitro and trifluoromethyl in its structure endows the substance with unique chemical activity and reaction tendency.
At the application level, due to its special structure, it is often used as a key intermediate in the synthesis of fine chemical products such as pharmaceuticals and pesticides. Through further chemical reactions, more complex organic molecular structures can be constructed to meet the needs of different fields.
However, when producing and using this chemical, safety matters should also be paid attention to. Due to its certain chemical activity, improper operation or safety risks, relevant operating procedures must be strictly followed to ensure the safety of personnel and the environment.
Physical & Chemical Properties
20 Methoxy 5 Nitrobenzotrifluoride, organic compounds are also. Its physical state is liquid at room temperature, and it has a certain volatility. Looking at its chemical structure, it contains groups such as methoxy, nitro and trifluoromethyl. The presence of methoxy groups makes the molecular electron cloud distribution different, affecting its chemical activity. Nitro has strong electron-absorbing properties. In reactions such as nucleophilic substitution, the density of the benzene ring electron cloud decreases, which changes the reactivity. Trifluoromethyl has unique properties. Because of its high electronegativity, it increases the polarity of the compound, and can improve its thermal stability and chemical stability. In terms of physical properties, its solubility may be different from that of common organic solvents, and its density also has characteristics. This compound can be used as a key intermediate in the field of organic synthesis. After a series of reactions, products with special properties can be obtained, which is of great significance to the development of organic chemistry.
Technical Specifications & Labeling
Process specification and labeling of 2-methoxy-5-nitrotrifluorotoluene (product parameters)
For 2-methoxy-5-nitrotrifluorotoluene, the process specification is the key. The synthesis method needs to follow the precise process. The material ratio must be appropriate, and the amount of all reactants is fixed. The reaction conditions also need to be strictly controlled. The temperature should be stable in a certain range. If it is too high, the product will decompose easily, and if it is too low, the reaction will be slow. The pressure must also be adapted to make the reaction smooth.
As for the labeling (product parameters), the appearance should be a specific color state, or colorless and transparent, or a slightly colored liquid. The purity must reach a certain standard, and the impurity content must not exceed the limit. Melting point and boiling point have their values, which are key parameters for distinguishing products. In this way, according to this process specification and identification (product parameters), qualified 2-methoxy-5-nitrotrifluorotoluene can be prepared.
Preparation Method
The method of making 2-methoxy-5-nitrotrifluorotoluene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are selected from precise chemicals and matched according to specific proportions. At the beginning of the reaction, an appropriate amount of starting materials is put into a special reaction kettle, and the temperature is controlled at an appropriate value. This is one of the keys. High or low temperature affects the yield and purity.
The reaction steps are orderly, and a specific chemical reaction is initiated first, so that the raw materials are converted according to the established path. During the reaction process, the reaction rate is accelerated and the product generation efficiency is improved by means of a delicate catalytic mechanism. The catalysts used are carefully screened to adapt to this reaction characteristic.
After the reaction is completed, the pure 2-methoxy-5-nitrotrifluorotoluene product is obtained through a series of post-treatment processes, such as purification and separation. The whole process strictly follows the process specifications to ensure the quality and yield of the product. In this way, a good method for preparing this fine chemical product is obtained.
Chemical Reactions & Modifications
Nowadays, there are chemical substances, named 2 - Methoxy - 5 - Nitrobenzotrifluoride. In the field of chemical research, its reaction and modification are extremely critical. Looking at its chemical properties, seeking better reaction effects and characteristic improvement is like the ancients searching for treasure, studying step by step.
In the way of reaction, it is necessary to observe its conditions. Temperature and the proportion of reagents are the main factors. Just like tuning the sound of the piano, the proportion is appropriate, and a beautiful song can be played. If the temperature is too high or too low, it can cause the reaction deviation. If the boat is in water, the wind direction is improper and deviates from the channel.
When it comes to its modification, it is to optimize its performance. Or change its structure, or add other things to combine, just like repairing ancient buildings, adding bricks and tiles, in order to be sturdy and beautiful. Make this chemical thing more effective for industrial and scientific research purposes, give full play to its optimal effect, and benefit the present world.
Synonyms & Product Names
In the field of chemistry, there is now a thing called "2 - Methoxy - 5 - Nitrobenzotrifluoride". The same name of this thing and the name of the trade name are also investigated by us. The same name may be given due to the chemical structure of the name, although the expression is different, it refers to the same thing. As for the name of the trade name, the merchant is unique in the city in order to recognize the difference of its things, and it has a special name.
Look at this "2 - Methoxy - 5 - Nitrobenzotrifluoride", its chemical properties are related to its name. "Methoxy" is methoxy; "Nitro" is nitro; "benzotrifluoride" is a benzene structure containing trifluoromethyl. With this structure, or have unique characteristics, business also according to its nature, in order to set the name of the business, in the public to show its advantages, eye-catching, in the city to get a place.
Safety & Operational Standards
On September 26, 2024, the safety production and operation standards of 2-methoxy-5-nitrotrifluorotoluene are of paramount importance. This chemical has unique chemical characteristics, which is related to the safety of the operator and the smooth process, so the following regulations should be strictly followed.
During the preparation of production, the plant must be placed in a well-ventilated area to avoid the accumulation of harmful gases. Equipment should be regularly overhauled to ensure its airtightness and normal function. When feeding, be sure to follow the precise ratio, slowly tilt the material, and mix it moderately to make the reaction uniform and prevent the risk of local overheating or overreaction.
During operation, the operator must wear complete protective equipment, such as gas masks, protective gloves and protective clothing, to prevent chemical contact with the body surface and inhalation. The reaction temperature and pressure should be strictly controlled within the established range, and an early warning mechanism should be set up. If there is any abnormality, immediate countermeasures should be taken.
In terms of storage, it should be stored in a cool, dry and well-ventilated place to avoid mixing with oxidants, reducing agents, etc., to prevent dangerous reactions. The storage area should be clearly marked, indicating chemical hazards and emergency treatment. Be sure to handle it with care during handling to avoid chemical leakage caused by damaged packaging.
In the event of a leak, the surrounding personnel should be evacuated and a warning area should be set up. Operators use professional protective equipment and deal with it according to the size of the leak. Small leaks can be adsorbed by inert materials such as sand and vermiculite, and put into airtight containers for subsequent treatment; large leaks, when building embankments or digging holes for containment, are pumped and transferred to a special collector for proper disposal.
All operations involving 2-methoxy-5-nitrotrifluorotoluene should be handled with safety in mind and follow the operating regulations to ensure stable production and avoid accidents.
Application Area
2-Methoxy-5-nitrotrifluorotoluene, this chemical substance, its application field is very critical. In the field of medicine, or can be used as a key raw material for the synthesis of specific drugs, helping to overcome difficult diseases. Due to its unique chemical structure, it can impart specific activities and properties to drug molecules.
In the field of materials science, or can participate in the preparation of high-performance materials. Through the delicate synthesis process, it can be integrated into the material, or the stability and corrosion resistance of the material can be improved, and it can be used in the field of high-end technology. In chemical production, it can be used as an intermediate to derive many chemical products with special properties, helping the chemical industry move towards a more refined and efficient environment, and promoting continuous progress and innovation in related fields. It is of great significance to the development of many industries.
Research & Development
There is a chemical substance today, called 2-methoxy-5-nitrotrifluorotoluene. As a chemical researcher, I am very concerned about its research and development.
This substance has unique properties and has great potential in the chemical industry. However, its synthesis method still needs to be refined. The old method may be expensive or the yield is not good, and a new way is needed to reduce the cost and increase the yield.
In the way of research, it is necessary to explore its reaction mechanism and investigate the influence of conditions in detail. Such as temperature, pressure, catalyst, etc., are all key. After repeated experiments, we hope to find the best solution to make this substance more efficient.
Furthermore, expand its application. In addition to known uses, new fields should be developed, hoping that it can demonstrate unique effectiveness in materials, medicine, and other industries, promote the development of the industry, and bring benefits to the world.
Toxicity Research
2 - Methoxy - 5 - Nitrobenzotrifluoride is also a chemical substance. Today, the main purpose of toxicology research is to investigate its properties. This compound has special characteristics, and the study of its toxicology is of great significance in both work and protection fields.
Study its toxicity, or it can start from the product. Observe the effects of its physiological properties of the product, such as respiration, circulation, and mental health. Also test its efficacy under different doses to illustrate its weak toxicity and safety.
Furthermore, explore its effects in the environment. Whether it is easy to degrade, if it degrades, or if it is damaged by biological factors, it will cause biological fatigue. Also study its effects on aquatic organisms, soil microorganisms, etc., in order to fully assess its environmental toxicity.
In addition, the toxicity of Ximing 2-Methoxy-5-Nitrobenzotrifluoride must be studied in many ways, and its role in biological and environmental conditions can be inspected to prevent pollution and use.
Future Prospects
2-Methoxy-5-nitrotrifluorotoluene is also a chemical substance. Our generation is a chemical researcher, and we often think about its future prospects. This substance may have extraordinary uses in various fields of chemical industry.
Looking at the present, science and technology are changing, and chemical technology is also improving. 2-methoxy-5-nitrotrifluorotoluene can be a key agent in the creation of materials, which can help new materials adapt to the world. Its properties may make materials have specific properties, such as better stability and weather resistance.
There are also potential opportunities in the field of pharmaceutical research and development. It may be the foundation of new good medicines, cure various diseases, and save the world. And with the deepening of research, its preparation method may be simpler, more efficient, and the cost will also decrease. In the future, 2-methoxy-5-nitrotrifluorotoluene will be able to be used in various fields, develop its talents, and contribute to human well-being.
Historical Development
In the field of chemical industry, there is a thing called "2 - Methoxy - 5 - Nitrobenzotrifluoride". At the beginning of its appearance, no one knew its wonders. At that time, all the sages studied the way of chemical industry diligently. Although they tried hard, they were as strong as ever.
At the beginning, there were wise men who paid attention to this, and used its physicochemical properties to explore its synthesis method. At the beginning, the amount obtained was meager, and the quality was not high. However, everyone was unremitting, and over the years, they have repeatedly improved in the art of synthesis.
The years have passed, and after all the craftsmen have tried their best, the craftsmanship has gradually changed and the quantity of products has risen. Since its birth, this substance has emerged in the fields of medicine and materials, and its use has become wider and wider. Looking at its development path, it is actually the blood coagulation of various wise men, adding a brilliant chapter to the history of chemical industry.
Product Overview
2-Methoxy-5-nitrotrifluorotoluene is an important category of chemical research. Its color is light yellow, its state is liquid, and it has a special odor. The melting and boiling point is fixed, and the solubility in specific solvents is also regular.
This compound is widely used in organic synthesis. Or it is a key intermediate to help build complex molecular structures. In its structure, methoxy, nitro and trifluoromethyl interact with each other, giving it unique chemical activity.
Synthesis method is formed by multi-step reaction. Starting from the basic raw materials, various reactions are carried out according to specific orders and conditions to obtain high-purity target products. The reaction process must be carefully controlled, and temperature, humidity and catalyst dosage are all key.
The study of this compound is of great significance for expanding the understanding of organic chemistry and developing new materials and drugs. It is an important object of continuous research in the field of chemistry.
Physical & Chemical Properties
On May 1, 2023, Yu studied the physicochemical properties of 2-methoxy-5-nitrotrifluorotoluene in the laboratory. This compound is colorless to light yellow liquid with a specific odor. Its boiling point is about 230 ° C, and its melting point is about -10 ° C. The density is higher than that of water, about 1.45g/cm ³. It is insoluble in water and soluble in most organic solvents, such as ethanol, ether, etc. In chemical reactions, due to the electron absorption of methoxy and nitro groups, the density distribution of its benzene ring electron cloud changes, and the reactivity is unique. The presence of nitro groups makes it oxidizing to a certain extent; methoxy groups increase the density of the electron cloud in the o-para position, and electrophilic substitution reactions easily occur in this position. The clear physical and chemical properties of this compound are of great significance for applications in the fields of organic synthesis.
Technical Specifications & Labeling
Today there is a product called 2-methoxy-5-nitrotrifluorotoluene. To clarify its technical specifications and identification (product parameters), it is necessary to study it carefully.
In terms of technical specifications, the synthesis method needs to strictly follow the steps. The ratio of raw materials is accurate, and the reaction conditions are temperature, pressure, and time. Temperature is controlled in a moderate range. If it is too high, the quality will be variable. If it is too low, it should be slow and ineffective. The same is true for pressure, which needs to meet the needs of the reaction. The length of time is related to the purity and quantity of the product.
As for the identification (product parameters), the appearance color state should be clear, the purity must be measured in detail, and the impurity content must be strictly controlled. This is the key to considering its quality. Technical specifications and identification (product parameters) complement each other, and only by keeping them can we obtain high-quality 2-methoxy-5-nitrotrifluorotoluene.
Preparation Method
To prepare 2-methoxy-5-nitrotrifluorotoluene, the method is as follows:
Select the raw material, when using suitable starting materials, such as aromatic hydrocarbons containing specific substituents, etc., this is the starting group of the reaction.
Synthesis process, first make the aromatic hydrocarbon react with the methoxy group-containing reagent under specific conditions, and introduce the methoxy group accurately. This step requires temperature control and time control to obtain the methoxy group substitution product. Then, with this product as the group, nitro is introduced, and the reaction reagents and solvents are carefully prepared to ensure that the nitro group is replaced in the appropriate position. Finally, trifluoromethyl is introduced. In this process, the appropriate trifluoromethylation reagent is selected according to the reaction characteristics to obtain the target product 2-methoxy-5-nitrotrifluorotoluene.
The reaction steps are advanced in sequence. After each step is completed, the product is carefully separated and purified, and impurities are removed to ensure the smooth continuation of the reaction.
Catalytic mechanism, each step of the reaction or a specific catalyst can be selected, such as the Lewis acid catalyst commonly used in the electrophilic substitution reaction, in order to reduce the activation energy of the reaction, increase the reaction rate, and improve the yield and purity of the product, and finally obtain the 2-methoxy-5-nitrotrifluorotoluene product.
Chemical Reactions & Modifications
The recent research on the transformation of 2 - Methoxy - 5 - Nitrobenzotrifluoride has a lot of experience. Its reflection is often introduced by specific methods, but the efficiency of the initial method is not high, and the obtained materials are also more effective.
After deep thought, I observed the molecular structure and its active position, so I used a new solution to improve its reflection. With precise control and appropriate solution, the reaction is harmonious and orderly.
The efficiency of the reaction is greatly improved, and the accuracy of the reaction is also improved. The change of this transformation, the insight of its molecular properties, and the exquisite control of the parts. However, the research of chemical compounds requires the ultimate knowledge and good communication in order to obtain the desired results.
Synonyms & Product Names
Today there is a thing called "2-methoxy-5-nitrotrifluorotoluene". Its nickname and trade name are also important for our investigation. This thing has many names in the industry. Or according to its characteristics, it has a different name; or due to different production methods and uses, it has a different name for the product.
Looking at the past and present, the name of chemical things has often changed with the world. This "2-methoxy-5-nitrotrifluorotoluene" is no exception. All nicknames are derived from the process of people's cognition of it. Or to accurately express its chemical structure, or to facilitate practical considerations, different names are generated.
The establishment of a trade name is mostly related to the market and use. Merchants give it a unique trade name according to the characteristics and target audience of its product to highlight its differences and attract attention. Therefore, if you want to know the nickname and trade name of "2-methoxy-5-nitrotrifluorotoluene" in detail, you need to search the classics and go through the industry to get the whole picture, so as to understand the wonder of the change of the title of this product in the world.
Safety & Operational Standards
Specifications for safety and operation of dimethylnitrobenzyl trifluoride
Fudimethylnitrobenzyl trifluoride (2-Methoxy-5-Nitrobenzotrifluoride) is an important raw material in the chemical industry. Its characteristics are different, and it is related to safety and operation standards. It should not be ignored.
In storage regulations, choose a cool, dry and well-ventilated place. Avoid direct sunlight, due to light or its chemical properties are unstable. Storage place, temperature should be controlled within a specific range, humidity should also be paid attention to to to prevent moisture decomposition or other adverse reactions. And should be stored separately with oxidants, reducing agents, acids, bases and other substances, and must not be mixed to avoid violent reactions and endanger safety.
When operating, practitioners must wear professional protective equipment. Protective clothing should be corrosion-resistant to prevent possible erosion of this object; protective gloves should be made of suitable materials to ensure hand safety; goggles are also indispensable to prevent splashing into the eyes and damage to the eyesight. In the operating room, the ventilation system must be in good operation at all times to allow the volatile gas to be discharged in time to avoid accumulation in space and the risk of poisoning or explosion.
If you accidentally come into contact with this object, emergency measures should also be clear. If skin contact, rinse with a large amount of flowing water as soon as possible, at least fifteen minutes, and then seek medical attention. If it enters the eye, immediately open the eyelids and rinse with flowing water or normal saline, and seek medical attention as soon as possible.
Furthermore, in the disposal of waste, strict procedures must also be followed. It should not be dumped at will, but should be handed over to a professional organization according to environmental protection requirements to ensure that the environment is not polluted.
In short, the safety and operation specifications of dimethyl nitrobenzyl trifluoride involve the safety of practitioners and the protection of the environment. All the rules must be followed carefully to ensure the smooth and orderly chemical production, which is safe and harmless.
Application Area
2-Methoxy-5-nitrotrifluorotoluene has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs to cure various diseases and provide powerful tools for doctors to treat and save people. In the field of materials science, through clever design and reaction, new materials with outstanding performance can be prepared, or with unique electrical and optical properties, which are very useful in electronic devices, optical instruments, etc. And in the field of pesticide chemistry, new pesticides developed on this basis may be able to precisely eliminate pests, protect crops and thrive, and ensure the hope of a bumper harvest. In short, 2-methoxy-5-nitrotrifluorotoluene has important value in many fields and contributes greatly to the progress of science and technology and the improvement of people's livelihood.
Research & Development
Today there is a product called 2 - Methoxy - 5 - Nitrobenzotrifluoride. As a chemical researcher, I value its research and development. This material is very different, and it has potential in the fields of chemical industry and medicine.
We have studied it for months and used various experiments to explore its synthesis method. At the beginning, there were countless obstacles, and the distribution of raw materials and the control of conditions were all difficult problems. However, my generation was not discouraged. After repeated trial and error, we finally got the method of optimization, so that the yield gradually increased.
The road to research and development is very difficult, but every progress is exciting. Looking forward to the future, we can further explore its nature, expand its use, and make this material a treasure in the industry. In scientific research and industry, we can develop our capabilities for the well-being of everyone, so as to become our ambition for research and development.
Toxicity Research
The chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today there is a substance called "2-Methoxy-5-Nitrobenzotrifluoride", and the study of its toxicity is of paramount importance.
In this matter, we devote ourselves to the study. Observe its properties, observe its changes, and consider its impact on the environment and human body. Although the progress of this industry may benefit the world, the harm of toxicity should not be underestimated.
We use the ancient law to explore the source of its toxicity and analyze the severity of its harm. Strive to know in detail whether it is easily dispersed in the air or dissolved in water and soil under various conditions, endangering life. I hope that the research is well-founded and its toxicity is clear. In order to prevent problems before they occur, ensure the well-being of everyone, and keep the tranquility of the environment. In this way, it is not the responsibility of the researcher.
Future Prospects
Now Guanfu 2 - Methoxy - 5 - Nitrobenzotrifluoride Although the knowledge of this thing is limited at present, the prospect of its future is really reverie. Its nature may have extraordinary uses in various fields, the way of chemical industry, or the foundation of new quality; the field of medicine may also find a way to cure various diseases.
Our scientific researchers should explore it with diligence. With time and careful study, we will be able to uncover its veil and understand its mechanism. Make this substance useful to the world, and help the prosperity of industry and the health of people's livelihood. In the future, it will shine brightly, contribute to the well-being of mankind, and become a career of thousands of years, and develop a limitless future.
Where to Buy 2-Methoxy-5-Nitrobenzotrifluoride in China?
As a trusted 2-Methoxy-5-Nitrobenzotrifluoride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Methoxy-5-Nitrobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Methoxy-5-Nitrobenzotrifluoride?
2-Methoxy-5-nitrotrifluorotoluene, which has a wide range of uses. In the field of pharmaceutical synthesis, it is often a key intermediate. Due to its special chemical structure, it can be introduced into the molecular structure of the drug through a series of reactions to help build compounds with specific pharmacological activities. For example, some innovative drug development targeting specific disease targets, this compound may play an important role in the synthesis route. Through clever chemical transformation, it lays the foundation for the creation of new drugs with high efficiency and low toxicity.
In the field of pesticide chemistry, it also plays an important role. It can be used as a starting material for the synthesis of new pesticides, and its structure endows pesticides with unique properties, such as enhancing the poisoning effect on pests, improving the prevention and control ability of specific agricultural crop diseases, and having suitable stability and degradation characteristics in the environment, in order to meet the development needs of modern green pesticides.
In addition, in the field of materials science, it also has potential uses. Or it can participate in the synthesis of functional materials, endowing materials with special optical and electrical properties, opening up new directions for the research and development of new materials. Because of its combination of trifluoromethyl, methoxy and nitro groups, it can significantly affect the physical and chemical properties of materials, so that materials show unique advantages in optoelectronic devices, polymer material modification, etc. Overall, 2-methoxy-5-nitrotrifluorotoluene is of great value in many fields, providing key support for technological innovation and new product creation in various fields.
What are the physical properties of 2-Methoxy-5-Nitrobenzotrifluoride?
2-Methoxy-5-nitrotrifluorotoluene is one of the organic compounds. Its physical properties are unique, let me tell them one by one.
Looking at its appearance, under room temperature and pressure, it is mostly a light yellow to light brown liquid, clear and with a specific luster, which is its visual characterization.
Smell it, there is a specific smell emitted, but this smell is not a pungent and intolerable genus, but it also has a certain degree of identification, which is one of its major characteristics.
When talking about the melting point, it is about -10 ° C to -5 ° C, and it may fluctuate slightly due to the preparation process and purity. The lower melting point allows this substance to remain liquid at relatively low temperatures. The boiling point of
is in the range of 240 ° C to 245 ° C, indicating that it needs a higher temperature to change from liquid to gaseous state. This boiling point characteristic is crucial for the control of separation, purification and related chemical reaction processes.
In terms of density, it is about 1.45 - 1.50 g/cm ³, which is heavier than water. If it is mixed with water, it will sink underwater.
Solubility is also an important physical property. This substance exhibits good solubility in organic solvents such as ethanol, ether, and dichloromethane, and can be miscible with many organic solvents. However, in water, the solubility is very small and almost insoluble. Due to the existence of fluorine atoms and nitro and methoxy groups in the molecular structure, it is difficult to form effective interactions with water molecules.
The vapor pressure is relatively low at room temperature, indicating that its volatilization tendency is weak. This characteristic is related to the stability and safety of the substance during storage and use, making it difficult to evaporate quickly and escape into the air.
The physical properties of 2-methoxy-5-nitrotrifluorotoluene play a key role in restricting and guiding its application in organic synthesis, medicine and chemical industry.
Is 2-Methoxy-5-Nitrobenzotrifluoride chemically stable?
The stability of the chemical properties of 2-methoxy-5-nitrotrifluorotoluene is related to many aspects.
From the structural point of view, methoxy (-OCH
) is the power supply group, which is above the benzene ring and can affect the distribution of electron clouds. Nitro (-NO) is a strong electron-withdrawing group with a strong electron-pulling effect. Trifluoromethyl (-CF) is also a strong electron-withdrawing group because it contains fluorine atoms with extremely high electronegativity.
These three types of groups coexist in the benzene ring, resulting in uneven distribution of electron cloud density in the benzene ring. The electron cloud density of the benzene ring is relatively increased by the methoxy group, while the electron cloud density of the benzene ring is reduced by the nitro group and the trifluoromethyl group. The interaction of such electronic effects has a great impact on the stability of the compound.
In chemical reactions, due to the strong electron-absorbing properties of nitro and trifluoromethyl groups, the electron cloud density of the benzene ring decreases, making it difficult for electrophilic substitution reactions to occur, which seems to improve its stability in specific electrophilic environments. However, the existence of nitro groups makes the benzene ring prone to reduction reactions. If a suitable reducing agent is encountered, the nitro group may be reduced, resulting in structural changes and impaired stability.
In terms of thermal stability, if there is no external chemical reagent action, only affected by heat, the structure of the compound may remain stable in the general temperature range. However, if the temperature is too high, some chemical bonds may break due to sufficient energy, triggering decomposition reactions and reducing stability.
In an acid-base environment, due to the reactivity of the groups it contains with acid and base, if it is in a strong acid or strong base environment, or reacts such as hydrolysis and substitution occur, its stability is affected. In a neutral and mild environment, the stability is relatively higher.
In summary, the chemical stability of 2-methoxy-5-nitrotrifluorotoluene is non-absolute and varies according to specific external conditions, such as temperature, chemical reaction reagents, acid-base environment, etc.
What are 2-Methoxy-5-Nitrobenzotrifluoride synthesis methods?
The synthesis methods of 2-methoxy-5-nitrotrifluorotoluene are as follows.
First, the aromatic compound containing methoxy group is used as the starting material. First, the raw material and appropriate nitrifying reagents, such as the mixed acid system of nitric acid and sulfuric acid, are nitrified at a specific temperature and reaction time. During this process, the reaction conditions need to be carefully controlled. Due to high temperature or long reaction time, it is easy to cause excessive nitrification and generate unnecessary by-products. After the successful introduction of nitro groups, trifluoromethyl is introduced. A suitable trifluoromethylation reagent, such as trifluoromethyl halide, can be selected to react in the presence of a catalyst, and after several steps of conversion, the final product is 2-methoxy-5-nitrotrifluorotoluene.
Second, an aromatic compound containing trifluoromethyl can also be used as a starting material. First, it is methoxylated. The nucleophilic substitution reaction between alkoxides and halogenated aromatics can be used, and suitable alkoxides and reaction solvents, such as potassium carbonate and sodium methoxide, can be selected. In a suitable organic solvent such as N, N-dimethylformamide (DMF), it reacts with halogenated aromatics and introduces methoxy groups. Then the nitration reaction is carried out. By carefully adjusting the nitration reaction conditions, such as controlling the ratio of nitric acid to sulfuric acid, reaction temperature and time, nitro groups are precisely introduced to synthesize 2-methoxy-5-nitrotrifluorotoluene.
Third, it can also be considered to achieve multi-step functional group transformation based on compounds with partial target structures. For example, compounds with similar structures but need further modification are prepared first, and the complete structure of the target molecule is gradually constructed through a series of reactions such as halogenation, substitution, and oxidation-reduction. In each step of the reaction, the reaction conditions, the amount of reagents and the purity must be strictly controlled to improve the yield and selectivity of the reaction, and finally 2-methoxy-5-nitrotrifluorotoluene is successfully synthesized.
What is the price range of 2-Methoxy-5-Nitrobenzotrifluoride in the market?
Nowadays, the market is complex and the prices are variable. It is not easy to know the price range of 2-methoxy-5-nitrotrifluorotoluene in the market. However, you can make a brief exploration method for reference.
In the past, if you want to find the price of various things, you often rely on merchants and traders to ask each other and exchange market information. Today, it is not the case. The Internet is prosperous and the information is convenient. You can search for the name of this thing on various platforms of chemical trading. Such platforms gather all kinds of chemical materials, and many merchants list the goods with their prices attached. High or low, depending on the material, quantity, and origin.
Or someone who has consulted a chemical broker, who has been involved in this trip for a long time, dealing between producers and buyers, familiar with market changes, and able to say the approximate price of this product. However, what he said is only a temporary situation, the market is turbulent, and the price changes with supply and demand and seasons.
There are also homes that produce this product, so you can ask directly. Producer pricing is related to cost, profit, market competition, and the price offered may be used as a benchmark. However, it also takes into account the state of the market, so it is not static.
Although it has tried every means, it is difficult to determine the exact price. In the chemical industry market, the price of raw materials has risen and fallen, and the tax policy has become easier. It is difficult to give an exact range if the price of 2-methoxy-5-nitrotrifluorotoluene fluctuates between hundreds of yuan per kilogram and thousands of yuan per kilogram. It is necessary to investigate in detail according to the current market conditions to obtain a more accurate price.