2-Fluoro-5-Nitrobenzotrifluoride

2-% tibia-5-aminotritibiacetic acid, although its name is not directly stated in the various materials involved in "Tiangong Kaiwu", it can also be investigated based on its properties.
Looking at the ancient chemical industry, pharmaceuticals, and smelting things, such things with special compound properties, or have their uses in the processing of pharmaceuticals, metal purification, etc. Ancient pharmaceuticals, if you want to make all kinds of medicines and achieve a delicate ratio, or you need to use such things that can adjust the physical properties. If you use pharmaceuticals, some mineral medicines are strong and difficult to tame, so you must use other things to accompany them and combine them before they can be used. 2 -% tibia-5-aminotritibiacetic acid may be used in the middle to ease the medicinal properties, or to help it fuse to form a good prescription.
In smelting and casting, when metal ore is smelted and purified, the removal of impurities and the improvement of metal texture often depend on special things. This kind of chemical agent may react with impurities in the ore to separate impurities and improve metal purity. Ancient sword casting pursues the beauty of combining rigidity and softness. If the metal is not pure, the sword is easy to fold or blunt. 2 -% tibia-5-aminotritibiacetic acid is used in this, or can make the metal texture of the cast sword more refined, making it a sharp weapon for cutting iron like mud.
Furthermore, in the ancient dyeing process, if you want to make the color uniform and lasting, you also need additives. When dyeing fabrics, the affinity between dyes and fabrics is related to the success or failure of dyeing. This compound may adjust the effect between dyes and fabrics, so that the dyeing effect is better, and the color of the dyed fabrics is bright and will not fade for a long time.
Although this object is not detailed in "Tiangong Kaiwu", it is inferred that 2-% tibia-5-aminotritibia acetic acid or in medicine, metallurgy, dyeing and other industries related to people's livelihood has important functions of auxiliary and improvement, and silently contributes to the improvement of various processes.

2-%E6%B0%9F-5-%E7%A1%9D%E5%9F%BA%E4%B8%89%E6%B0%9F%E7%94%B2%E8%8B%AF%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E5%A6%82%E4%B8%8B%EF%BC%9A
The melting and boiling point of this substance is quite low. Due to its weak intermolecular force, it is mostly maintained by van der Waals forces, resulting in its melting point of about minus tens of degrees Celsius, and its boiling point is not high. Under normal temperature and pressure, it is very easy to change from liquid to gaseous state, showing a volatile state.
Its density is smaller than that of water. Due to its molecular structure, the molecular stacking is not very tight, and the mass contained in a unit volume is less, so it will float on the water surface when placed in water.
In terms of solubility, it has good solubility in organic solvents. Because its molecules have a certain degree of non-polarity, according to the principle of "similar miscibility", in organic solvents such as ethanol and ether, it can interact well with solvent molecules to achieve dissolution; however, in water, the solubility is poor, water is a polar solvent, and it is difficult to match the force between the molecules of the substance, so it is difficult to dissolve in water in large quantities.
This substance also has flammability. The proportion of carbon and hydrogen in its molecules is quite high. Under suitable conditions, after full contact with oxygen and reaching the ignition point, it can burn violently, releasing a lot of heat and generating products such as carbon dioxide and water. This flammability makes it suitable for use as a fuel in some scenarios, but it is also necessary to pay attention to the safety of fire and explosion protection. In addition, the volatile nature of the substance makes its odor more pronounced. During use and storage, attention should be paid to ventilation to avoid adverse effects on the human respiratory tract.

2-%E6%B0%9F-5-%E7%A1%9D%E5%9F%BA%E4%B8%89%E6%B0%9F%E7%94%B2%E8%8B%AF%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E5%B9%B6%E9%9D%9E%E5%AE%9A%E7%84%B6%E7%A8%B3%E5%AE%9A.
In this compound, there are specific atomic arrangements and chemical bonding forms. The 2-hydroxyl and 5-amino groups in its structure will exhibit different chemical activities due to changes in the surrounding chemical environment, such as pH, temperature, solvent properties, etc. In acidic environments, amino groups may undergo protonation, which in turn affects the charge distribution and spatial structure of molecules, resulting in reduced chemical stability.
From the perspective of reactivity, hydroxyl and amino groups are active check points and easily participate in various chemical reactions. Hydroxyl groups can undergo esterification, etherification and other reactions, while amino groups can participate in nucleophilic substitution, amidation and other processes. During these reactions, the original structure of the molecule is changed, further indicating that its chemical properties are not absolutely stable.
In addition, if the compound is in an aerobic environment and the presence of suitable catalysts, oxidation reactions may occur, causing changes in its structure and properties. Even under relatively mild conditions, long-term storage may gradually change its chemical composition and properties due to slow chemical reactions or interactions with certain components in the air.
In summary, the chemical properties of 2-hydroxy-5-aminotriethylsilica are not stable, but will change due to a variety of internal and external factors.

To prepare 2-hydroxy-5-aminotrifluorotoluene, the following methods are used:
First, an aromatic compound containing suitable substituents is used as the starting material. The fluorine atom is introduced at a specific position in the aromatic ring first, which can be used to react with the corresponding halogenated aromatic hydrocarbon with a fluorine-containing reagent by means of a nucleophilic substitution reaction. After fine control of the reaction conditions, such as temperature, solvent and catalyst, the fluorine atom is precisely occupied. Then, through nitration reaction, the nitro group is introduced at the appropriate position in the aromatic ring. This step requires careful selection of the mixed acid ratio of nitric acid and sulfuric acid and the reaction temperature according to the substrate activity to achieve the ideal regioselectivity. The nitro group is then reduced to an amino group, and the nitro group is gradually converted to an amino group by catalytic hydrogenation or a metal and acid system, such as iron powder and hydrochloric acid. Finally, through the hydroxylation reaction, the hydroxyl group is introduced at a specific position, and the nucleophilic substitution of phenolic compounds or the metal-catalyzed oxidation reaction can be used to achieve the synthesis of 2-hydroxy-5-aminotrifluorotoluene.
Second, a specific halogenated aromatic hydrocarbon can also be used as the starting material. Trifluoromethyl is first introduced, and trifluoromethylation reagents, such as Grignard reagents such as trifluoromethyl magnesium halide, are commonly used, and are connected to aromatic rings through nucleophilic substitution After that, according to the sequence of first nitration, then reduction of nitro to amino group, and finally hydroxylation, the reaction parameters are carefully adjusted in each step to obtain the target product. During this period, each step of the reaction needs to be separated and purified, such as column chromatography, recrystallization and other methods to remove impurities, ensure the purity of the product, and gradually construct the molecular structure of 2-hydroxy-5-aminotrifluorotoluene.

When storing and transporting 2-% hydroxyl-5-aminotrihydroxyethyl ether, pay attention to the following key points.
One is storage. Be sure to choose a cool and dry place, because the substance may be sensitive to temperature and humidity, and the high temperature and humidity may cause its properties to change, resulting in damage to its quality. And ensure that the storage place is well ventilated to prevent the accumulation of harmful gases. If the ventilation is not smooth, or the substance volatilizes to produce harmful gases, it will not only threaten the safety of personnel, but also affect the stability of the substance itself. Furthermore, it should be stored separately from oxidants, acids, etc., because of its active chemical properties, contact with these substances may trigger violent chemical reactions, such as combustion, explosion and other serious accidents.
The second is related to transportation. Before transportation, it is necessary to carefully check whether the packaging is intact. If the packaging is damaged, substances or leaks during transportation will not only pollute the environment, but also pose safety hazards. During transportation, the temperature should be strictly controlled, and the appropriate temperature range should be maintained according to its characteristics to avoid large fluctuations in temperature. At the same time, the transportation vehicle must be equipped with corresponding fire equipment and leakage emergency treatment equipment to prevent accidents. The escort personnel also need professional training, familiar with the characteristics of the substance and emergency treatment methods, pay close attention to the situation during transportation, and once any abnormalities are detected, they will be properly disposed of immediately according to the regulations.
All these precautions are to ensure the safety and stability of 2-% hydroxyl-5-aminotrihydroxyethyl ether during storage and transportation, and must not be negligent to avoid accidents.