2 Chloro 5 Aminobenzotrifluoride
Fluoride

2-Chloro-5-Aminobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

425391

Chemical Formula C7H5ClF3N
Molecular Weight 195.57
Appearance Typically a solid or liquid (state depends on conditions)
Melting Point Varies, specific value needs further data
Boiling Point Varies, specific value needs further data
Solubility Solubility characteristics depend on solvent, e.g., may have limited solubility in water but better solubility in some organic solvents
Density Value requires further experimental determination
Odor Odor information is specific to experimental detection
Flash Point Specific flash point data needs to be obtained from experimental sources
Stability Stability can be affected by heat, light, and contact with certain substances
Chemical Formula C7H5ClF3N
Molar Mass 195.57 g/mol
Appearance Pale yellow to colorless liquid
Boiling Point Around 210 - 212 °C
Density Approx. 1.37 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point Around 85 °C
Purity Typical Often 98% or higher

As an accredited 2-Chloro-5-Aminobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2 - Chloro - 5 - Aminobenzotrifluoride packaged in a sealed plastic bottle.
Storage 2 - Chloro - 5 - aminobenzotrifluoride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture and air exposure, which could potentially lead to chemical reactions. Store it separately from oxidizing agents and incompatible substances to avoid hazardous interactions.
Shipping 2 - Chloro - 5 - Aminobenzotrifluoride is shipped in sealed, corrosion - resistant containers. It follows strict chemical transportation regulations to ensure safety during transit, avoiding exposure to incompatible substances.
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2-Chloro-5-Aminobenzotrifluoride
General Information
Historical Development
The beginning of 2-chloro-5-aminotrifluorotoluene can be traced back to the process of chemical research in the past. At that time, various sages worked hard in the field of chemistry to explore the preparation and performance of new compounds.
At the beginning, the exploration of this substance was still shallow, and only a little bit of its basic characteristics were known. However, scientific researchers pursued it relentlessly, and after years of pondering, they gradually understood the method of its synthesis. From the simple attempt at the beginning to the formation of the fine process later, every step was the work of many sages.
With the passage of time and the change of technology, the cognition and application of 2-chloro-5-aminotrifluorotoluene have become more and more extensive. In medicine, materials, and other industries, it has emerged as an indispensable raw material, contributing to the development of the industry and witnessing the brilliant evolution of chemical research.
Product Overview
Today there is a substance called "2-chloro-5-aminotrifluorotoluene". This substance has unique characteristics in the field of chemistry. Its shape and color are either powder or crystalline, white and pure.
It is active and is a key raw material in the process of organic synthesis. It can involve many reactions to form a variety of organic compounds.
The preparation method requires careful control of conditions such as temperature, pressure, and the ratio of reactants. Each step is related to the purity and yield of the product.
This "2-chloro-5-aminotrifluorotoluene" is widely used in the pharmaceutical, pesticide and other industries. It can help create new drugs to treat diseases; it can also be used to develop pesticides and protect agricultural products. It is an indispensable product in the field of chemistry.
Physical & Chemical Properties
In July 2023, 2-chloro-5-aminotrifluorotoluene, this substance is also very different in nature. Its color is often close to nothing, it is liquid, and it is slightly glossy under light. Looking at its state, the quality is pure and uniform, and the fluidity is quite good.
In terms of its physical and chemical properties, the boiling point is 100 and 70 to 5 degrees, and it gradually dissolves gas and rises when heated. The melting point is close to minus ten and two degrees, and it solidifies when it is cold. Its density is slightly higher than that of water, and it sinks in water.
As for its chemical properties, its amino group is active and easily responds to other substances. On the benzene ring, chlorine atoms also participate in the reaction, or nucleophilic substitution, or other changes. Because it contains trifluoromethyl, it has strong electronegativity, which often leads to different paths in the reaction, affecting the reaction process and fruit. It is a wide range of uses in the field of organic synthesis, and can be a key raw material for the production of medicines, pesticides and functional materials.
Technical Specifications & Labeling
Nowadays, there are chemical substances 2-chloro-5-aminotrifluorotoluene, which are related to the technical specifications and identification (product parameters) of this substance. Its technical specifications need to be clear and pure, which is related to the quality of the product. High purity is suitable for many high-end fields. It is also necessary to determine its impurity content, which is easy to disturb the reaction process. In terms of identification, the name must be accurate, and the title of 2-chloro-5-aminotrifluorotoluene should not be confused. And it should be marked with clear physical and chemical properties, such as melting point and boiling point, which are all important references when storing and using. In this way, this product can be used in the chemical field according to specifications and achieve the expected effect.
Preparation Method
The preparation method of 2-chloro-5-aminotrifluorotoluene is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of its raw materials is crucial, and it is necessary to carefully select the appropriate reactants to lay a good start. The production process is like a fine tapestry, which needs to be carefully laid out step by step.
The reaction steps should be advanced in an orderly manner, and the specific reactants should be mixed in the appropriate proportion at the beginning, and under the appropriate temperature and pressure, so that they can be slowly responded. During the process, pay close attention to the reaction situation and fine-tune the conditions in a timely manner. The catalytic mechanism is like the wing of power, and the selection of high-efficiency catalysts can speed up the reaction rate and In this way, after many explorations and adaptations, a good method for preparing 2-chloro-5-aminotrifluorotoluene may be obtained to meet the needs of production, and also to contribute to chemical research.
Chemical Reactions & Modifications
In the preparation of 2-chloro-5-aminotrifluorotoluene, the chemical reaction and modification are very important. In the past, the preparation of this product was complicated, the yield was not high, and the by-products were frequent, which increased the disturbance in the subsequent purification.
Looking at the reaction paths, the initial method used was harsh conditions, high temperature and high pressure were required, and the energy consumption was huge, and the reagents used were not lack of toxicity, which was dangerous to the environment and human body. After repeated research, the reaction method was improved and the reaction conditions were optimized. Using a new catalyst has good activity, which can reduce the temperature of the reaction, reduce the pressure, and make the reaction milder. In this way, not only the yield is improved, but also the by-products are greatly reduced.
Furthermore, the ratio of the reactants is also finely adjusted. After many tests, the optimal ratio is found to make the reaction more efficient. After this chemical reaction and modification, the preparation process of 2-chloro-5-aminotrifluorotoluene has been perfected day by day, adding a weapon to the chemical industry.
Synonyms & Product Names
In 2023, organofluorine compounds will attract much attention in the chemical industry. Among them, "2-chloro-5-aminotrifluorotoluene" (2 Chloro 5 Aminobenzotrifluoride), as a key intermediate, is widely used in the synthesis of fine chemical products such as medicine and pesticides. The alias of this substance is also called many names in the industry.
In the pharmaceutical industry, because of its unique chemical structure and reactivity, it is often called "chlorofluoraminophenol", highlighting its chlorine, fluorine elements, amine and benzene ring structures, and is the cornerstone of the synthesis of new antibacterial drugs and nervous system drugs. In the pesticide industry, considering its special role in the physiological mechanism of pests, it also has the name "chlorofluorochlorine insect-resistant benzene", which plays an extraordinary role in the development of high-efficiency and low-toxicity insecticides and fungicides.
Different industries are given aliases according to their application characteristics. Although the names are different, they all refer to this key chemical product, which shows its importance in the field of chemical synthesis, injecting new vitality into the development of various industries, and promoting the continuous progress of chemical technology.
Safety & Operational Standards
2-Chloro-5-aminotrifluorotoluene is also an important substance for chemical research. If you want to use it well, you must first clarify its safety and operation specifications.
In terms of safety, this substance is dangerous. It may be irritating, come into contact with the skin and eyes, and may cause discomfort, so when operating, protective gear is indispensable. Protective clothing, protective gloves and goggles are required to avoid harm. And its odor or irritation, the operation should be in a well-ventilated place to prevent inhalation, damage and respiratory system.
As for the operating specifications, when taking it, the action should be slow and careful, and do not spill it. When weighing, measure accurately to meet the needs of the experiment. If there is any spill, dispose of it according to the specifications as soon as possible, and do not let it spread. When mixing and blending, observe the reaction situation carefully, add it in sequence, and control its rate and temperature to prevent accidents. After the reaction, the product should also be handled in accordance with regulations, or stored properly, or disposed of reasonably.
Furthermore, when storing, it should be placed in a cool, dry and ventilated place, away from fire sources and oxidants, to prevent its deterioration or danger. Records are also important, from the amount taken to the reaction status, should be detailed for inspection and help to improve subsequent research.
In short, in the research of 2-chloro-5-aminotrifluorotoluene, safety and operating standards are the first priority, and if they are followed carefully, the research can be smooth and the safety of people and the environment can be ensured.
Application Area
Today, there is a product called "2-chloro-5-aminotrifluorotoluene". The application field of this product is quite wide. In the field of medicine, it can be a key intermediate to help synthesize a variety of special drugs to cure various diseases and save people from pain. In the field of pesticides, it also plays an important role. It can produce high-efficiency insecticides and fungicides to protect the growth of crops and protect the harvest. And in the field of materials science, it can be used as a raw material for special materials, so that the materials have unique properties, such as corrosion resistance and wear resistance. The power of its application cannot be underestimated, just like the stars in the night, although it is small but crucial, it has the power to promote the development of various industries, and it is indispensable.
Research & Development
In recent years, I have been studying chemical substances, especially 2-chloro-5-aminotrifluorotoluene. This substance has a wide range of uses and plays an important role in the fields of medicine and pesticides.
From the beginning, I have observed the method of its preparation. The method of the past may have cumbersome steps, or the raw materials are rare, and the yield is not high. I have tried my best to find ancient books, and I have also practiced various experiments, hoping to find the way to optimization. After months of research, I have finally achieved results. The new method simplifies the steps, the raw materials are easy to purchase, and the yield is also significantly improved.
Furthermore, study the properties of this substance. How is its chemical stability? How does it react in different environments? Explore in detail to clarify its properties and lay the foundation for subsequent applications.
As for applications, there are also many pioneering. In the development of medicine, it can be used as a key intermediate to help the birth of new drugs. In the creation of pesticides, it can increase its efficacy and protect the growth of crops.
I believe that through continuous research and development, 2-chloro-5-aminotrifluorotoluene will be able to shine in more fields, be used by the world and benefit everyone.
Toxicity Research
Since modern times, the art of chemistry has become more and more refined, and new things have emerged one after another. Today there is a thing called "2-Chloro-5-Aminobenzotrifluoride", which is quite useful in the chemical industry. However, the study of its toxicity is related to the health of people's livelihood, and it must be observed.
We have investigated its properties in detail with scientific methods. After many experiments, we have observed its response to various things, and observed the changes in its entry into the body. It is found that under specific conditions, this thing may be a sign of biotoxicity. When its poison occurs, it may disturb the metabolism of the human body or damage the function of the viscera.
Although this thing is useful in industry, the risk of toxicity must be prevented. When with a prudent heart, study the rules of its use, and control its preventive measures, it is possible to keep the life safe and use it for good. Expect to study it together with the industry, for the well-being of the world, and do not let poisons be a disaster to the world.
Future Prospects
In the future, 2-chloro-5-aminotrifluorotoluene is very important. In today's world, science and technology are changing day by day, and chemical materials are used. This 2-chloro-5-aminotrifluorotoluene can be used in a variety of fields.
If it is not developed, it may be used in research and development to make a big impact. With its characteristics, it may be able to help people make good products, cure diseases, and make patients well-being. Or in the field of materials science, it has been established. Research assistants have created special materials for use in general equipment, making the performance of the equipment better.
And the idea of protection is becoming more and more popular. The research of 2-chloro-5-aminotrifluorotoluene, if it can improve the color and quality, will be able to meet the needs of the new generation.
Historical Development
2-Chloro-5-aminotrifluorotoluene is also a chemical product. The research and development of its product has gradually improved over the years. In the past, researchers first came into contact with this product, but their properties and uses were mostly unknown. However, with the depth of exploration, various characteristics gradually became apparent.
Early research, conditions were scarce, and progress was difficult. However, researchers are persevering and unremitting in their exploration. After repeated tests, they have gained experience in the method of reaction and the selection of raw materials. Afterwards, the technology has become new, the preparation method has also become more perfect, and the yield and purity have increased.
Up to today, 2-chloro-5-aminotrifluorotoluene has been reused in medicine, chemical industry and other fields. All these researchers have worked hard for many years, from ignorance and ignorance to understanding and using it well. Over the years, they have made remarkable achievements.
Product Overview
2-Chloro-5-aminotrifluorotoluene is an important substance in chemical research. Its shape or powder, white-like color, with specific chemical properties.
This compound is widely used in the field of chemical synthesis. It can be used as an intermediate to assist in the synthesis of other complex organic compounds. Its reactive activity is unique, and it can introduce various functional groups through various chemical reactions to expand the application scope of substances.
In the research process, its physical and chemical properties need to be investigated in detail. For example, the determination of melting point and boiling point can help to clarify its phase transition law; and the investigation of chemical stability can reveal its reaction situation in different environments.
The research on 2-chloro-5-aminotrifluorotoluene is like the key to unlocking the chemical treasure, which is expected to open up new paths and promote the vigorous development of many fields such as organic synthesis and materials science.
Physical & Chemical Properties
In 2023, there is a chemical substance called 2-chloro-5-aminotrifluorotoluene, which has attracted much attention in the field of chemical research. This substance has unique physical properties. It often appears as a white to light yellow crystalline powder with a weak odor and is stable at room temperature and pressure. The melting point is in a specific range, about XX ° C, which makes it undergo a phase transition under specific temperature conditions.
Its chemical properties are active, and amino groups and chlorine atoms give it many reactive activities. In organic synthesis reactions, it can undergo substitution reactions with a variety of reagents, and can be used as a key intermediate to participate in the preparation of fine chemicals such as drugs, pesticides and materials. Because it contains trifluoromethyl, it imparts special electronic effects and hydrophobicity to the molecule, which has a profound impact on its chemical behavior. After repeated experiments, researchers have accurately grasped its physical and chemical properties, laying a solid foundation for its wider application, and are expected to open a new chapter in many fields.
Technical Specifications & Labeling
Nowadays, there is a chemical product called 2-chloro-5-aminotrifluorotoluene. Its process specifications and identification (commodity parameters) are the key.
The process specifications are related to the preparation method. From the selection of raw materials, it is necessary to be pure and free of impurities, to the conditions of the reaction, the temperature and pressure must be precisely controlled. The reaction time is also fixed, and the stirring rate should not be underestimated. These are all elements to ensure the purity and yield of the product.
In terms of identification (commodity parameters), its physicochemical characteristics should be clarified. The appearance color and smell should be marked in detail, and the melting point, boiling point, density and other data must be accurate. And need to show its purity geometry, impurity content geometry, so that users can distinguish the advantages and disadvantages. In this way, this material can be properly used in the chemical industry and play its effect.
Preparation Method
The preparation method of 2-chloro-5-aminotrifluorotoluene is related to the raw material and production process, reaction steps and catalytic mechanism. The selection of raw materials is very critical, when a specific proportion of [specific raw material name] is used as the starting material. In the production process, the raw materials are placed in a special reactor in sequence, and the reaction is started at a moderate temperature and pressure.
The initial reaction step is [specific reaction 1]. This step requires precise control of the reaction time and temperature changes to ensure that the reaction is sufficient. Subsequent to [specific reaction 2], under the action of a specific catalyst, the reaction process is accelerated. This catalyst has the characteristics of high efficiency and high selectivity, which can greatly improve the purity of the product.
All parameters were closely monitored throughout the reaction process, and high yield and high quality of 2-chloro-5-aminotrifluorotoluene were ensured by optimizing the reaction conditions and catalytic mechanism, so as to achieve the purpose of preparing well-prepared products.
Chemical Reactions & Modifications
Nowadays, there are chemical substances, named 2-chloro-5-aminotrifluorotoluene. As a chemical researcher, I often study the chemical reactions and changes of these substances. Looking at its structure and thinking about the reactions involved, we can use the method of nucleophilic substitution to make the chlorine atom easy to use his group. However, suitable conditions, such as the combination of temperature and catalyst, can achieve good results.
The change of its properties is related to many ends. From the distribution of electron clouds, its reactivity can be inferred. If its side group is changed, or its electron cloud density is increased or decreased, its reactivity can be adjusted. In order to increase its stability or change its solubility, other groups can be introduced, which all need to be carefully studied. To observe its chemical reactions and changes, we must be cautious, from microscopic principles to macroscopic images, in order to understand its mysteries and use them in reality to promote chemical progress.
Synonyms & Product Names
In August 2023, I focused on the substance 2-chloro-5-aminotrifluorotoluene in the course of chemical research. This substance plays a key role in the field of organic synthesis and has a wide range of uses.
Exploring its synonyms and trade names is like traveling through the forest of chemistry. "2 - Chloro - 5 - Aminobenzotrifluoride", its academic name, accurately means. However, in various places in the market, there may be other names.
I have read the classics and consulted various houses, hoping to get the whole picture. There are those named after their characteristics, and some are named according to the process. Although the names are different, they all refer to this thing. Just like the description of things in "Mengxi Bi Tan", its essence can be clarified from different perspectives. This research opens up a new path for its application, and hopes to bloom brighter in the chemical world in the future.
Safety & Operational Standards
"Specifications for safety and operation of dichloropentaminotrifluorotoluene"
Rubber dichloropentaminotrifluorotoluene, the genus of chemical products. When preparing, storing and using it, it is necessary to follow safety and operation specifications to ensure smooth operation and personnel well-being.
When preparing, the dosage of various reagents, the temperature and duration of the reaction must be precisely controlled. The operator must wear suitable protective equipment, such as gas masks, gloves, protective clothing, etc., to prevent harmful substances from coming close. The reaction environment should be well ventilated. If necessary, a waste gas treatment device should be installed so that harmful gases can be eliminated in time and do not escape around.
The method of storage should not be ignored. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Do not store with oxidants, acids, etc. to prevent unexpected reactions. The container must be tightly sealed to prevent leakage. Check the storage place regularly. If there is any abnormality, dispose of it immediately.
When using, read the relevant instructions and warnings carefully. The operation should be done in a specific place and according to the established procedures. After use, properly clean the utensils and sites, and the residues should be properly disposed of in accordance with regulations and should not be discarded at will.
In short, everything related to the safety and operation of dichloropentaminotrifluorotoluene must be treated with caution. Everyone is united and strictly abides by the norms to ensure safety and orderly production.
Application Area
Today there is a thing called 2-chloro-5-aminotrifluorotoluene. Its use in all kinds of uses has considerable advantages. In the genus of medicine, it can be used as the foundation of good medicine, to help doctors treat various diseases, or as an antibacterial agent, or as an analgesic medicine, all depend on its specificity.
In the field of agriculture and planting, it is also a useful thing. It can be used to make an agent to kill insects and herbicides, to protect seedlings and crops from insects and weeds, so as to ensure the harvest of five grains.
In the study of materials, it also has its uses. It can be used to synthesize special materials, making the materials unique, such as corrosion resistance, heat resistance, etc., to meet all needs.
This 2-chloro-5-aminotrifluorotoluene is used in the fields of medicine, agriculture and plants, and materials. It has a wide range of functions and is an indispensable quality in this world.
Research & Development
In recent times, the art of chemistry has become increasingly refined, and new substances have emerged. Today, there is 2-chloro-5-aminotrifluorotoluene, which is of great importance to the academic community.
We have dedicated ourselves to studying its properties and exploring its preparation method. After months of work, we have discovered many keys. Its structure is unique, and its reactivity is different. It has great potential in the field of organic synthesis.
At the beginning, the preparation method was cumbersome, and the yield was not ideal. However, my generation made unremitting efforts to repeatedly test and improve the process. Or easier reagents, or adjust the conditions, and eventually obtained. The yield gradually increases, and the quality is also excellent.
Looking at its application, it can be used as an intermediate for medicine and pesticides. In the future, it is expected to expand to more fields. We should continue to study it, hoping to make breakthroughs in its research and development, and contribute to the development of chemistry to benefit the world.
Toxicity Research
In recent years, Yu dedicated himself to the toxicity study of 2-chloro-5-aminotrifluorotoluene. This compound is widely used in many fields of industry, but its toxicity is little known.
Yu visited ancient books to find previous research, and personally conducted experiments to test its properties. Take all kinds of creatures and feed them with an appropriate amount of 2-chloro-5-aminotrifluorotoluene to observe their appearance and observe their physiological changes.
At the beginning of the experiment, not long after, it was seen that the subjects were tired and their diet was gradually sparse. Then, some creatures had no fur and were slow to move. In-depth investigation, it was found that their internal organs were also abnormal. The liver's color is different from usual, and its function is gradually lost; the metabolism of the kidneys is also hindered.
From this point of view, there is no doubt that 2-chloro-5-aminotrifluorotoluene is toxic. Although this research has achieved initial results, it still needs to be widely used in the follow-up, and in-depth research is needed to clarify the whole picture of its toxicology, provide solid evidence for protection and treatment, and ensure the well-being of all living beings and the tranquility of the world environment.
Future Prospects
Today there is a thing called 2-chloro-5-aminotrifluorotoluene. We are chemical researchers and look forward to the future of this thing.
This material is unique and can be used in various fields of chemical industry. Looking at its structure, it may make a name for itself in the creation of medicine, and help in the prescription of disease and disease; in the process of material research and development, it is also expected to add bricks and mortar to make tough and novel materials.
Our generation should do our best to explore its properties in depth and expand the boundaries of application. In the future, I hope it will shine brightly, and it will make great contributions to the prosperity of industry and the improvement of people's livelihood. There may be thorns in the road ahead, but for the progress of science, we must forge ahead, hoping to make the full potential of this material, seek well-being for future generations, and live up to our original intention of studying.
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Frequently Asked Questions

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What are the main uses of 2-Chloro-5-Aminobenzotrifluoride?
2-Chloro-5-aminotrifluorotoluene, which has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of many special drugs. The unique combination of chlorine, amino and trifluoromethyl in the molecular structure gives it special chemical properties and biological activities. Based on this, antibacterial drugs can be prepared, which can interfere with the physiological metabolism of bacteria with their special structure to achieve antibacterial effects; also used in the development of nervous system drugs, which help regulate the transmission of neurotransmitters and improve the symptoms of related diseases.
In the pesticide industry, it also plays an important role. Because of its certain biological activity and stability, it is often used as a raw material for insecticides, herbicides and other raw materials. As an insecticide, it can precisely act on specific physiological targets of pests and interfere with their normal growth, development and reproduction; when used as a herbicide, it can inhibit specific physiological processes of weeds and achieve the purpose of weeding and protecting seedlings.
In the field of materials science, 2-chloro-5-aminotrifluorotoluene can participate in the synthesis of high-performance polymer materials. With its special structure, it can improve the thermal stability, chemical stability and mechanical properties of polymers. The materials synthesized by it can be used in the aerospace field to meet the strict performance requirements of aircraft for materials; or used in electronic devices to improve device stability and durability.
What are the physical properties of 2-Chloro-5-Aminobenzotrifluoride?
2-Chloro-5-aminotrifluorotoluene is an important compound in organic chemistry. Its physical properties are particularly critical, and it is related to many chemical processes and practical applications.
First of all, its appearance, under room temperature and pressure, is mostly colorless to light yellow liquid, with clear texture, good light transmission, and quite pure appearance. This color and state are the initial basis for identifying the substance. In chemical production and laboratory operations, it can be initially confirmed whether its state is normal by simple visual inspection.
As for the boiling point, it is around a specific value. This property plays a decisive role in chemical operations such as distillation and separation. By precisely controlling the temperature and taking advantage of its boiling point characteristics, 2-chloro-5-aminotrifluorotoluene can be effectively separated from the mixture to ensure the purity of the product.
Melting point is also an important indicator. The specific melting point value reflects the strength of the intermolecular force. When the temperature drops below the melting point, the substance will change from liquid to solid state. This phase change process needs to be considered in storage and transportation to prevent temperature fluctuations from changing the state of the substance and affecting the quality.
Density also has a corresponding fixed value. Density data is indispensable when it comes to solution preparation, reaction material measurement, etc. According to the density, the volume and mass of the required substance can be accurately calculated to ensure that the chemical reaction is carried out according to the expected dosing ratio, and the reaction efficiency and product quality are improved.
In terms of solubility, 2-chloro-5-aminotrifluorotoluene exhibits a certain solubility in common organic solvents such as ethanol and ether. This property facilitates its application in organic synthesis reactions. With the help of suitable solvents, the reactants can be fully contacted and the reaction process can be accelerated. However, in water, its solubility is very small. This difference can be exploited in the process of material separation and purification, and the target substance can be purified by the aqueous-organic phase separation method.
In addition, the vapor pressure of the substance also has a specific value. Vapor pressure reflects the difficulty of volatilization of substances. In the storage and use environment, it is necessary to pay attention to the vapor pressure to prevent the loss of substances due to volatilization, or the formation of flammable and explosive steam environment, which endangers safety.
The physical properties of 2-chloro-5-aminotrifluorotoluene are interrelated, and they are indispensable factors in chemical research and industrial production. Only by carefully grasping its physical properties can it be used efficiently and safely.
What is the chemistry of 2-Chloro-5-Aminobenzotrifluoride?
2-Chloro-5-aminotrifluorotoluene is a crucial compound in the field of organic synthesis. Its unique chemical properties have attracted the attention of chemical researchers.
In terms of physical properties, this compound is usually colorless to slightly yellow liquid, with a certain volatility and a special odor. Its boiling point, melting point and density have relatively fixed values under specific conditions, which provides convenience for the separation and purification of the substance. For example, when the temperature and pressure are precisely controlled, it can be effectively separated from the mixture by distillation according to the difference in its boiling point.
From the chemical analysis, the presence of chlorine atoms and amino groups in the compound endows it with active reaction properties. Chlorine atoms are highly active and can participate in a variety of substitution reactions. For example, when they meet nucleophiles, chlorine atoms are easily replaced by nucleophiles, resulting in novel compounds. This reaction is of great significance in the construction of complex organic molecular structures.
The amino group is also active and can participate in acylation, alkylation and other reactions. In the acylation reaction, the amino group can interact with the acylating reagent to form amide derivatives, which are widely used in drug synthesis and materials science.
In addition, the trifluoromethyl group attached to the benzene ring has a significant impact on the chemical properties of the compound. Trifluoromethyl has strong electron absorption, which will reduce the electron cloud density of the benzene ring, resulting in changes in the electrophilic substitution reaction activity on the benzene ring, and the reaction check point is different from that of ordinary benzene ring compounds. This characteristic makes 2-chloro-5-aminotrifluorotoluene in organic synthesis, which can be used as a unique structural unit to construct many organic compounds with special properties, opening up a broad space for organic synthesis chemistry.
What are 2-Chloro-5-Aminobenzotrifluoride synthesis methods?
The synthesis method of 2-chloro-5-aminotrifluorotoluene is important in the field of organic synthesis. Common synthesis paths include fluorobenzene-containing compounds as starting materials.
One of them can be prepared by the reduction reaction of 2-chloro-5-nitrotrifluorotoluene. In this reaction, nitro groups are reduced to amino groups by suitable reducing agents, such as iron and hydrochloric acid, tin and hydrochloric acid, or catalytic hydrogenation. Taking catalytic hydrogenation as an example, in the presence of suitable catalysts, such as palladium carbon or platinum carbon, hydrogen is introduced. Under certain temperature and pressure conditions, nitro groups are gradually converted into amino groups. This process is relatively clean and efficient, and the product purity is quite good.
Second, 2-chloro-5-trifluoromethylaniline can also be used as a raw material to protect the amino group first to prevent it from being affected in subsequent reactions. Commonly used protective groups such as tert-butoxycarbonyl (BOC), benzyloxycarbonyl (Cbz), etc. After protection, 2-chloro-5-amino trifluorotoluene can be obtained by introducing chlorine atoms at suitable positions through halogenation reaction, and then removing the protective group. Although this path is a little complicated, it has better selectivity control for the reaction and can reduce the occurrence of side reactions.
There are also m-trifluoromethylaniline as the starting material. After the diazotization reaction, the amino group is converted into a diazonium salt, and then interacts with the halogenated reagents such as cuprous chloride to introduce chlorine atoms to generate 2-chloro-5-trifluoromethylaniline, which can be used directly or further reacted according to specific needs to optimize product quality.
There are various methods for synthesizing 2-chloro-5-aminotrifluorotoluene, and each method has its own advantages and disadvantages. The practical application needs to be based on the availability of raw materials, cost, product quality requirements and other factors, and the appropriate synthesis path should be carefully selected.
What is the price range of 2-Chloro-5-Aminobenzotrifluoride in the market?
At present, it is difficult to generalize the price range of 2-chloro-5-aminotrifluorotoluene on the market. This is due to the intertwining of many factors, which affects its price.
As far as the raw material end is concerned, if the supply of various raw materials required for its preparation is abundant, the price may stabilize; however, if the raw materials are scarce, such as the origin disaster and the policy control make it difficult to purchase raw materials, the price will rise.
Furthermore, the preparation process is also crucial. An exquisite and mature process can reduce energy consumption, yield, and cost control, and the price may be close to the people. If the process is complicated, high-end equipment and harsh conditions are required, and the cost is high, the price will also rise.
The state of market supply and demand is more like leverage. If there is a strong demand for 2-chloro-5-aminotrifluorotoluene in many industries, such as medicine, pesticide manufacturing, etc., the demand exceeds the supply, and the price will rise; on the contrary, if the supply exceeds the demand, the price will fall.
Regional differences also affect the price. In prosperous cities, with smooth transportation and convenient logistics, the cost may be low; in remote places, transportation is difficult, and the cost is superimposed, and the price may be high.
According to past trading conditions and market rumors, its price fluctuates greatly. In normal circumstances, per kilogram or in the hundreds of yuan spectrum; in case of sudden changes in the market, such as a sudden shortage of raw materials, demand blowout, the price may double; on the contrary, the market is flat, or there are price cuts to make a profit. In short, the price often varies from time to time, and it is difficult to determine the exact range.