2 Chloro 4 Nitrobenzotrifluoride
Fluoride

2-Chloro-4-Nitrobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

588456

Chemical Formula C7H3ClF3NO2
Molecular Weight 225.55
Appearance Colorless to light yellow liquid
Boiling Point 220 - 222 °C
Melting Point 18 - 20 °C
Density 1.54 g/cm³
Solubility In Water Insoluble
Vapor Pressure Low
Flash Point 98 °C
Refractive Index 1.496 (20 °C)
Chemical Formula C7H3ClF3NO2
Molecular Weight 225.55
Appearance Colorless to yellow liquid
Boiling Point 227 - 229 °C
Melting Point 19 - 21 °C
Density 1.524 g/cm³
Vapor Pressure 0.05 mmHg (25 °C)
Solubility In Water Insoluble
Flash Point 99 °C
Refractive Index 1.492 (20 °C)

As an accredited 2-Chloro-4-Nitrobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2 - Chloro - 4 - Nitrobenzotrifluoride packaged in a sealed, chemical - resistant bottle.
Storage 2 - Chloro - 4 - Nitrobenzotrifluoride should be stored in a cool, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and bases to avoid potential reactions. Ensure proper labeling for easy identification and handling.
Shipping 2 - Chloro - 4 - Nitrobenzotrifluoride is shipped in tightly - sealed, corrosion - resistant containers. Compliance with strict chemical shipping regulations is ensured. Hazard labels are clearly affixed, and transport is arranged with carriers experienced in handling such chemicals.
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2-Chloro-4-Nitrobenzotrifluoride
General Information
Historical Development
At the beginning of the 20th century, organic chemistry flourished, and many novel compounds were discovered one after another. "2 - Chloro - 4 - Nitrobenzotrifluoride" This compound came to the fore. At that time, the atmosphere of chemical research was enthusiastic, and researchers were fascinated to explore.
At first, the understanding of it only stayed at the basic structure level. As the research deepened, people gradually knew its unique chemical properties. Early experimental conditions were simple, it was difficult to obtain the compound, and the yield was also low. But the ancestors were not discouraged. After countless attempts, they improved the synthesis method.
As time went by, science and technology advanced, and new instruments and technologies emerged. The efficiency of synthesizing "2 - Chloro - 4 - Nitrobenzotrifluoride" was greatly improved, and the purity was also significantly improved. It has promising applications in materials science, medical chemistry, and other fields, laying the foundation for further research and wide application.
Product Overview
2-Chloro-4-nitrotrifluorotoluene, an organic compound. Its shape is colorless to light yellow liquid, with a special odor. The boiling point is quite different, and the melting degree also has its value. It is widely used in the field of organic synthesis. It can be used as an intermediate to prepare a variety of drugs, pesticides and pigments. Because of its unique structure, it contains chlorine, nitro and trifluoromethyl groups, which give it special chemical properties. The chlorine atom makes the compound nucleophilic substitution activity, the nitro group can increase its reactivity and polarity, and the trifluoromethyl group changes the physical and chemical properties of the compound. The preparation method is often obtained from specific raw materials through nitrification, halogenation and other reactions. However, the preparation conditions need to be carefully managed to maintain the yield and purity. This compound holds an important position in the chemical industry and is relevant to the production of many downstream products.
Physical & Chemical Properties
2-Chloro-4-nitrotrifluorotoluene is also an organic compound. Its physical properties are colorless to light yellow liquid at room temperature, with a special odor, boiling point is about a certain value, and the density is heavier than water. Its chemical properties are quite active due to the presence of chlorine, nitro and trifluoromethyl groups. Chlorine atoms can undergo substitution reactions. Nitro groups reduce the electron cloud density of the benzene ring, making it difficult to cause electrophilic substitution reactions. The strong electron absorption of trifluoromethyl affects the polarity and reactivity of the molecule as a whole. This compound is widely used in the field of organic synthesis. It can be used as an intermediate to produce a variety of medicines, pesticides and materials. The study of its physicochemical properties is of great significance in expanding the path of organic synthesis and developing new substances. It can provide strong support for the progress of related industries.
Technical Specifications & Labeling
An example of technical specifications and labels (commodity parameters) for 2-chloro-4-nitrotrifluorotoluene products in the chemical industry in 2023:
There are 2-chloro-4-nitrotrifluorotoluene products today, and their preparation needs to follow a specific method. The raw materials are selected as a fine review, and the ratio must be accurate. In the reactor, the temperature is controlled at XX degrees Celsius to promote its synthesis at a specific time.
Its properties should be colorless to slightly yellow liquid, with a special smell. Physical parameters such as boiling point and melting point should conform to the established standards. The purity must not be less than XX%, and the impurity content must be strictly controlled within XX. On the
label, its chemical name is "2-chloro-4-nitrotrifluorotoluene", and a warning label is attached to indicate its toxicity, corrosiveness and other characteristics, so that users can know in detail and ensure the safety of use.
Preparation Method
The method of making 2-chloro-4-nitrotrifluorotoluene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials need to be carefully selected to achieve the best quality. The production process follows a rigorous sequence.
First take a certain raw material and put it into the reactor in an appropriate proportion. Controlling the temperature to a suitable degree is the key to the success or failure of the reaction. Add other ingredients in sequence, stirring continuously during the process to make the substances mix evenly. The reaction steps follow the established rules and proceed gradually without disorder.
Catalytic mechanism, select the appropriate catalyst to promote the rapid progress of the reaction and increase the yield. This process needs to be carefully controlled, observe the state of the reaction, and fine-tune it in a timely manner to obtain high-quality 2-chloro-4-nitrotrifluorotoluene. Every step is taken with care to produce the best product.
Chemical Reactions & Modifications
2-Chloro-4-nitrotrifluorotoluene, this chemical substance is related to reaction and modification, and I often study it. Its reaction also requires careful observation of conditions, temperature, pressure, and catalyst are all important. In the past, under conventional conditions, the reaction was slow and the yield was not as expected. So we thought about the method of modification, and wanted to adjust its molecular structure and change its activity.
I looked at ancient books, found something similar, and tried to imitate it. First change the catalyst, replace the old one with a new agent, and the reaction rate is slightly increased. Then adjust the temperature, rise it moderately, and then too high will cause side reactions.
The effect of the solvent was later observed, and the polarity was different, and the results were good. The yield increased, and the quality of the product was also excellent. Although this process is difficult, it is of great significance for the progress of chemistry. In the future, we should continue to study it, and hope to find a better way to promote the reaction and modification of this chemical product.
Synonyms & Product Names
The 2023 Nobel Prize in Chemistry was awarded to Morten Meldal, Carolyn R. Bertozzi, and K. Barry Sharpless for their contributions to the development of click chemistry and biological orthogonal chemistry. Click chemistry, and in particular the concepts proposed by Sharpless, represent a simple and reliable method for synthesizing molecular fragments together quickly and with the same efficiency as clicking a button.
In the vast field of chemical synthesis, the compound 2-Chloro-4-nitrotrifluorotoluene (2-Chloro-4-Nitrobenzotrifluoride) occupies a unique position. The exploration of its synonyms and trade names is of great significance to chemical researchers. Synonyms such as specific chemical nomenclature variants reflect the different names of chemical substances in different academic or industrial contexts, while trade names are the identification of the compound in commercial circulation. By studying these names in depth, researchers can more accurately track the application of the substance in scientific research, production and other links, and clarify its importance in different fields. The various names of this compound are like nodes in a chemical knowledge network, linking together synthesis paths, reaction characteristics, market demand, and many other information, providing strong clues for the further expansion of chemical research and application.
Safety & Operational Standards
"Code for the safe production and operation of 2-chloro-4-nitrotrifluorotoluene"
Fu 2-chloro-4-nitrotrifluorotoluene is also a chemical substance, and it is widely used in the chemical industry. However, its nature is risky, and it is related to safe operation, so it cannot be ignored.
The production environment is the first heavy equipment. All utensils should be firm and tight to prevent leakage. The equipment used must comply with precise regulations, and be inspected and repaired regularly to ensure its safety.
When operating, the operator must abide by strict regulations. Wear protective gear, clothing with anti-chemical materials, gloves, and masks are also indispensable to protect their skin and breathing. The method of operation, follow the order, do not act rashly. The dosage and speed of medicinal materials are fixed, and be cautious.
Furthermore, the factory should be well ventilated to drain its foul gas and make the air fresh. If there is a sign of leakage, take emergency measures as soon as possible. Cut off the source first, and then swarm people, and remove the danger of leakage by professional methods.
When storing, place it in a cool and dry place, away from fire and heat sources. Classify and store, do not mix with things that are taboo. Keep fire-extinguishing and adsorption materials in the warehouse for emergencies.
The road of transportation should not be taken lightly. Choose the appropriate equipment, install it steadily, and avoid shocks. The escort knows its nature and knows the emergency method.
In short, the safe production and operation of 2-chloro-4-nitrotrifluorotoluene are interlinked, which is related to human life and wealth. Everyone is united, strictly abide by the norms, and there will be no trouble.
Application Area
2-Chloro-4-nitrotrifluorotoluene, the application field of this substance, is very important. In the field of pharmaceutical synthesis, it is a key intermediate, which can help create a variety of specific drugs to cure various diseases and bring good news to people with diseases. In the field of pesticide preparation, with its unique chemical properties, it can make powerful pesticides, protect crops from insect infestation, and ensure the harvest of grain. In the field of material research and development, it has also emerged, or it can improve material properties, making materials more tough and durable. From this perspective, 2-chloro-4-nitrotrifluorotoluene is of great significance in many fields, and its application prospects are as bright as the rising sun. It will play a pivotal role in the development of various industries and contribute to the progress of society.
Research & Development
In recent years, Yu devoted himself to the chemical industry, focusing on the research of 2-chloro-4-nitrotrifluorotoluene. At the beginning, explore its physical and chemical properties, observe its molecular structure and characteristics in detail, know its melting point and dissolution, and lay the foundation for subsequent use.
Then, study its preparation method. Try various paths, or improve the old method, or explore new ways. After repeated experiments, adjust the reaction conditions, control the temperature, pressure, and material ratio, in order to obtain an efficient and pure preparation method. During this period, encountering many obstacles, the yield of the reaction did not meet expectations, and the removal of impurities was quite difficult. However, I was not discouraged, and after repeated research, I finally found an optimization strategy to improve yield and purity.
Looking to the future, I hope to expand its application field based on this. In the pharmaceutical and pesticide industries, explore their new uses, and hope to contribute to the development of the industry, promote the continuous progress of this chemical, and use it in a wider range, making every effort for the prosperity of the chemical industry.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today there is a substance name "2-Chloro-4-Nitrobenzotrifluoride", and its sexual toxicity should be investigated in detail.
The color state of this substance needs to be carefully observed, whether it is a liquid or a solid, and its appearance should be observed to clarify its initial nature. Its smell is also the key. Whether it is pungent or not is related to its volatile characteristics and harm. As for its dissolution in various solvents, water, alcohol, ether, etc., all need to be tested to know the possibility of its diffusion.
Furthermore, its impact on organisms should not be underestimated. Take insects, rats, etc. as a test, and observe their physiological changes, differences in behavior, and if they have convulsions or sluggishness, they are all signs of toxicity. And in the environment, the difficulty of degradation and the way of transformation should be clarified to prevent the spread of pollution and endanger all things.
Researching the way of toxicity is like facing the abyss, and it must be rigorous in order to ensure the safety of all beings and the peace of the environment.
Future Prospects
I have tried to study chemical things, and now I look at 2 - Chloro - 4 - Nitrobenzotrifluoride this product, thinking about its future development, and I have a feeling.
This material is special, and it may be useful in many fields. Looking at the world today, science and technology are changing, and the chemical industry is also following suit. This product may be used in the synthesis of medicine, adding strength to the medicine to remove diseases; or in the development of materials, adding new materials to the heterogeneity.
Although it is used today, it may still be limited, but the future scene can be looked forward to. With time, those who are waiting for research will be refined and complete in technology, and they will definitely be able to emerge. Or as the key to industrial innovation, opening a new chapter; or as the stone of academic breakthroughs, laying the foundation for the road ahead. The future exhibition is limitless, we should look forward to it, with diligence, to promote its prosperity, to be used by the world, and to benefit people.
Historical Development
In 2023, in the field of organic chemistry, 2-chloro-4-nitrotrifluorotoluene emerged. This compound has unique chemical properties and is becoming increasingly important in many fields.
Looking back in the past, the journey of chemical exploration has been long. In the past, scholars studied organic synthesis and worked tirelessly to find new paths. At the beginning, it was difficult to synthesize this substance, the reaction conditions were harsh, and the yield was low.
However, the researchers were perseverant, and technological innovations emerged with the passage of time. New catalytic systems were discovered, and the reaction conditions were optimized, resulting in improved yield. Nowadays, the preparation process of 2-chloro-4-nitrotrifluorotoluene is becoming more and more mature, and it is widely used in the fields of medicine and materials, which adds a strong color to the development of chemistry and promotes the continuous progress of related industries.
Product Overview
Today there is a substance called "2-chloro-4-nitrotrifluorotoluene". This substance is a chemical product and is quite useful in the field of chemistry. Its properties are unique, and its color and texture can be described. Looking at it, it may be a specific color, a certain form, or a different texture. Its use is also wide, and it plays an important role in many chemical processes, as a raw material, or as a medium. The method of synthesis has been studied by many craftsmen and has a mature path. According to specific steps, following precise proportions, its output can be controlled. However, the preparation and use of this substance also need to be treated with caution, because it may involve safety and is related to the state of the environment. Therefore, when studying and applying, we should exercise caution and abide by regulations in order to make the best use of everything and ensure a safe and secure environment.
Physical & Chemical Properties
There is a substance named 2-chloro-4-nitrotrifluorotoluene. The physical and chemical properties of its substance are related to many things. Looking at its properties, under normal temperature, or in a specific state. Its melting point and boiling point are the keys to physical characterization. The melting point is the critical temperature at which the substance changes from solid to liquid state; the boiling point is the key node at which the liquid state changes to gaseous state.
When it comes to chemical properties, in its molecular structure, chlorine, nitro and trifluoromethyl interact. Chlorine atoms have certain reactivity and can participate in substitution in many reactions. The presence of nitro groups changes the electron cloud distribution of this substance, affecting its chemical reactivity. The special structure of trifluoromethyl gives it unique chemical stability and hydrophobicity. The physical and chemical properties of this substance are of great significance in many fields such as chemical engineering and materials, affecting its preparation, application and storage.
Technical Specifications & Labeling
In 2024, the process specifications and labeling (product parameters) of 2-chloro-4-nitrotrifluorotoluene are related to the process specifications of this product and need to follow a rigorous process. The selection of raw materials must be pure, the reaction conditions must be precisely controlled, the temperature must be constant in the appropriate range, and the pressure must also conform to the standard. The reaction time should strictly follow the established procedures, so as not to make deviations. As for the label, the name "2-chloro-4-nitrotrifluorotoluene" should be written in a prominent font on the product packaging, and the key product parameters, such as purity geometry, impurity content, etc., should be listed in detail, so that the user can clearly understand the product characteristics, ensure the safety and compliance of use, and play its due role in chemical applications.
Preparation Method
The method of preparing 2-chloro-4-nitrotrifluorotoluene is related to the raw materials and production process, reaction steps and catalytic mechanism. First, take an appropriate amount of trifluorotoluene as the base material, use it as the starting material, and add an appropriate amount of mixed acid composed of nitric acid and sulfuric acid to a specific reactor. This is the key to the nitrification reaction. The temperature is controlled in a suitable range, about 50 to 60 degrees Celsius, so that it can fully react. After several hours, 4-nitrotrifluorotoluene can be obtained.
Then, transfer 4-nitrotrifluorotoluene into a new kettle, add an appropriate amount of chlorine gas, and with the help of a specific catalyst such as an iron-based catalyst, heat up to about 120 to 130 degrees Celsius, and carry out the chlorination reaction. After several times of reaction, careful monitoring until the reaction is complete. Subsequent separation and purification methods, such as distillation, extraction, etc., remove impurities and finally obtain pure 2-chloro-4-nitrotrifluorotoluene products. Strict control of each step in this process can ensure product quality and yield.
Chemical Reactions & Modifications
In the field of chemistry, the reaction and modification of 2-chloro-4-nitrotrifluorotoluene are very important.
In the past, the reaction of this compound often followed the formula, but the product was obtained, or it was not perfect. If you want to change it, you must think of a new way. The wisdom of ancient times, in the art of chemistry, often study the mechanism, in order to improve the old method.
In order to make the reaction of 2-chloro-4-nitrotrifluorotoluene more effective, you need to observe the structure of its molecules and study the change of its bond energy. Or new agents can be introduced to adjust the reaction environment, so that the atomic rearrangement is orderly and the product is pure. And when modifying, environmental protection and convenience are taken into account, so that the process is optimized and the efficiency is improved. In this way, it can live up to the original intention of chemical research, seek benefits for the industry, and promote the prosperity of chemical industry.
Synonyms & Product Names
November 10, 2023, sunny.
Today in the laboratory, we are focusing on the analysis of 2-chloro-4-nitrotrifluorotoluene, a compound. This compound has a wide range of uses in the chemical industry and is key to many industrial processes.
Thinking about its synonyms and trade names, it is like looking for treasures in ancient books. People in the industry commonly call it an alias, either to help memory, or because of historical evolution. And trade names are chosen by merchants in order to recognize their characteristics and advantages.
2-chloro-4-nitrotrifluorotoluene, its synonyms may be related to structural characterization, accurately reflecting the molecular composition; the trade name is market-oriented, either showing high purity or outstanding performance. Both are key elements of industry communication and trade, such as boats in rivers, helping this product to flow smoothly in the sea of chemical industry.
I will continue to cultivate deeply, explore more mysteries of it, and contribute to the development of chemical industry.
Safety & Operational Standards
About 2-chloro-4-nitrotrifluorotoluene Product Safety and Operating Specifications
Fu 2-chloro-4-nitrotrifluorotoluene is an important chemical in the chemical industry. It is used in many aspects of industrial production, but because of its certain hazards, safety and operating standards are of paramount importance.
Safety, this chemical is irritating, and contact with skin, eyes or inhalation of its vapor can cause discomfort. Therefore, when working, protective measures are essential. Those engaged in related work, when wearing protective clothing, the protective clothing must have good anti-penetration performance, which can effectively block chemical contact with the skin. Protective gloves must be worn. The material of the gloves should be resistant to chemical corrosion to ensure the safety of the hands. Eye protection is also indispensable. Goggles or masks should be able to completely cover the eyes to prevent chemicals from splashing in.
The operating specifications should not be underestimated. When storing, it should be placed in a cool and ventilated place, away from fire and heat sources. Because it is easy to decompose due to heat, harmful gases are generated, which endangers safety. The storage area should also be stored separately from oxidants and alkalis, and must not be mixed to prevent chemical reactions and accidents.
During use, the operation should be mechanized and automated as much as possible to reduce direct contact between personnel and chemicals. When taking it, the action should be cautious and precise to avoid spilling. If a leak occurs accidentally, do not panic. In the event of a small leak, it can be absorbed by inert materials such as sand and vermiculite, collected in a closed container, and properly disposed of. If a large leak requires immediate evacuation of personnel, delineation of a warning area, and activation of an emergency response plan. Use professional equipment to contain the leak to prevent it from spreading and polluting the environment.
Anyone involved in the work related to 2-chloro-4-nitrotrifluorotoluene should be familiar with this safety and operation code, and always be vigilant, so as to ensure production safety and avoid accidents.
Application Area
2-Chloro-4-nitrotrifluorotoluene is also a chemical product. Its application field involves a wide range of. In the field of pharmaceutical synthesis, it can be a key intermediate to help create special drugs and cure various diseases. In the field of pesticide preparation, it can be used as an active ingredient to give pesticides strong insecticidal and sterilization ability, and protect the growth of crops.
Guanfu Industrial Production, it can participate in the synthesis of special materials, making the materials have unique properties and suitable for special environments. Such as in the manufacture of electronic devices, it can optimize material characteristics and improve the efficiency of electronic equipment.
Furthermore, in the path of scientific research and exploration, it provides important materials for chemical research, helps researchers to understand the reaction mechanism, and opens up new fields of chemical knowledge. Its application in many fields is constantly expanding and deepening, and will contribute more great power to human life and scientific and technological progress.
Research & Development
Taste the chemical industry, related to people's livelihood, the new research of its things, quite laborious. Today there is a thing, called "2 - Chloro - 4 - Nitrobenzotrifluoride", which is the focus of chemical research. Our research aims to clarify its nature and make good use of it.
At the beginning, explore its structure to know its fundamental characteristics. After repeated experiments, understand its chemical nature, and lay the foundation for subsequent use. Also observe its response to various things, and hope to expand its path.
During the research and development, strive to improve, so that this thing can be used in industry, medicine and other fields. Despite all the difficulties, we are still working tirelessly to achieve great things and contribute to the development of the chemical industry to benefit everyone.
Toxicity Research
2-Chloro-4-nitrotrifluorotoluene is also a chemical substance. In the study of its toxicity, it is of paramount importance. Today, we study its properties to clarify its harm.
The color and taste of this substance should be investigated first. Its pungent, or light in color, can be used to remove it.
Then explore its entry into the body, or from breathing into the lungs, or from the skin, or because of food. Entry into the body, the performance of the body.
The appearance of the body, the performance of its spirit and physiology. Or weak vitality, lack of food, and even worse, the five.
And this thing also dissipates in the environment. Or tired in the soil, water, and biological environment. Therefore, in the use and disposal of this thing, be cautious, and seek the harm of its toxicity, to protect the safety of life, and to clear the environment.
Future Prospects
I try to devote myself to the research of 2-chloro-4-nitrotrifluorotoluene. This material is unique, and in the field of chemical industry, it must have extraordinary uses. Although the research is not complete at present, my heart looks to the future, and I hope it will be greatly developed.
Watching the things of the past, at first hidden in the dark, after the efforts of many wise people, it shines brightly, and it is well received by all people. The same is true of 2-chloro-4-nitrotrifluorotoluene. I expect that in the way of pharmaceutical synthesis, it can be the foundation of wonderful medicines, saving patients from sinking diseases; in the way of material creation, it can become a strange material, meeting the needs of the world.
In the future, the more refined the technology to be researched, the more capable it will be. Or in the industry of environmental protection, help energy conservation and emission reduction; or in high-tech, introduce the old and lead the change. This is my vision for its future, and I am willing to unswervingly promote its success, use it for the world, and live up to my generation's research heart.
Where to Buy 2-Chloro-4-Nitrobenzotrifluoride in China?
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Frequently Asked Questions

As a leading 2-Chloro-4-Nitrobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Chloro-4-Nitrobenzotrifluoride?
2-Chloro-4-nitrotrifluorotoluene is a crucial raw material in the field of organic synthesis and is widely used in many industries.
Its primary use lies in the field of pharmaceutical synthesis. By using this as a starting material for specific chemical reactions, a variety of compounds with unique pharmacological activities can be prepared. For example, in the synthesis path of some drugs used to treat specific diseases, 2-chloro-4-nitrotrifluorotoluene acts as a key intermediate. Through reactions such as substitution and addition with other organic reagents, complex drug molecular structures are gradually constructed to achieve therapeutic effects.
Furthermore, in the field of pesticides, this compound also plays an indispensable role. It can be used as an important raw material for the synthesis of new pesticides. Because of its specific chemical structure and properties, the pesticides generated through a series of reactions have high efficiency in killing pests, and have relatively little impact on the environment. It can precisely act on specific physiological targets of pests and interfere with their normal physiological activities, thus achieving the purpose of controlling crop diseases and insect pests and ensuring crop yield and quality.
In addition, in the dye industry, 2-chloro-4-nitrotrifluorotoluene is also an important synthetic raw material. Based on this, through clever design of chemical reactions, various dyes with bright colors and good stability can be prepared. These dyes are widely used in textile, printing and dyeing industries, giving fabrics rich and diverse colors to meet people's needs for textile aesthetics.
In short, 2-chloro-4-nitrotrifluorotoluene occupies an important position in the pharmaceutical, pesticide, dye and other industries due to its unique chemical properties, providing a key material basis for the development of various industries.
What are the physical properties of 2-Chloro-4-Nitrobenzotrifluoride?
2-Chloro-4-nitrotrifluorotoluene, its physical properties are as follows:
This compound is mostly liquid at room temperature. It is clear and has a specific color, or it is colorless to light yellow. Its odor is unique, irritating, and pungent. This smell is derived from its chemical structure.
When it comes to boiling point, it is usually in a specific temperature range, about 240-250 ° C. This boiling point varies slightly depending on external pressure conditions. The value of boiling point indicates that it needs to apply energy at this temperature to transform it from liquid to gas.
The melting point is also a key physical property, roughly around -10 ° C. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. Under this temperature, the compound takes the form of a solid state.
Its density is larger than that of water, about 1.6 g/cm ³, so in water, this substance will sink.
In terms of solubility, 2-chloro-4-nitrotrifluorotoluene is insoluble in water. Because water is a polar solvent, and the polarity of this compound is weak, according to the principle of "similar miscibility", the two are insoluble. However, it is soluble in many organic solvents, such as ethanol, ether, acetone, etc. In organic synthesis reactions, these organic solvents are often used to dissolve them and facilitate the reaction.
In addition, the vapor pressure of this compound is relatively low at room temperature, which means that its degree of volatilization is not very high, but in high temperature environments, the vapor pressure increases and the volatilization intensifies, so it is necessary to be careful to prevent the harm caused by its vapor.
What is the chemistry of 2-Chloro-4-Nitrobenzotrifluoride?
2-Chloro-4-nitrotrifluorotoluene, this is an organic compound. It has unique chemical properties and is of great concern to chemical research and industrial applications.
First of all, its physical properties are mostly liquid under normal conditions, with certain volatility, and because of the fluorine atom, the molecular polarity is different, and it has good solubility in common organic solvents, such as ethanol, ether, etc., but it is difficult to dissolve in water.
In terms of chemical properties, chlorine atoms are highly active and can undergo nucleophilic substitution reactions. Taking co-heating with sodium hydroxide aqueous solution as an example, chlorine atoms will be replaced by hydroxyl groups to form 2-hydroxy-4-nitrotrifluorotoluene. In this reaction, hydroxide ions act as nucleophiles to attack the carbon atoms connected to chlorine, and chlorine ions leave.
Furthermore, nitro groups are also active groups, with strong electron-absorbing properties, which can reduce the electron cloud density of the benzene ring and increase the difficulty of electrophilic substitution reactions on the benzene ring. However, under certain conditions, such reactions can still occur, and nitro groups can be reduced. For example, with iron and hydrochloric acid as reducing agents, nitro groups can be converted into amino groups to obtain 2-chloro-4-aminotrifluorotoluene.
In addition, the presence of trifluoromethyl groups greatly affects molecular properties. It has a strong electron-absorbing induction effect, which not only affects the acidity of the compound, but also affects its chemical stability and biological activity. Due to its high stability and good fat solubility, this substance is widely used in the synthesis of medicine and pesticides, and can be used as a key intermediate to create new compounds with specific biological activities.
In summary, 2-chloro-4-nitrotrifluorotoluene occupies an important position in the field of organic synthesis due to its diverse chemical properties, providing possibilities for the preparation of many fine chemicals.
What is 2-Chloro-4-Nitrobenzotrifluoride production method?
The preparation of 2-chloro-4-nitrotrifluorotoluene is an important field of investigation in chemical processes. In the past, several routes were often followed to prepare this compound.
First, trifluorotoluene is used as the starting material. First, it is nitrified with the nitrate under specific reaction conditions. This step requires careful control of the reaction temperature, proportion of reactants and reaction time. Usually in a suitable solvent environment, such as a mixed system of sulfuric acid and nitric acid, trifluorotoluene can undergo electrophilic substitution reaction with the nitrate, and the nitro group is introduced into the benzene ring to form 4-nitrotrifluorotoluene. Subsequently, the obtained 4-nitrotrifluorotoluene is chlorinated under the action of appropriate chlorination reagents, such as chlorine gas or chlorine-containing compounds, in the presence of catalysts. This chlorination process also requires precise regulation of various reaction parameters, so that chlorine atoms can smoothly replace hydrogen atoms at specific positions on the benzene ring to obtain 2-chloro-4-nitrotrifluorotoluene.
Second, other compounds containing fluorine, chlorine and nitro groups are also synthesized through multi-step reactions. For example, fluorine-containing compounds with convertible functional groups are first prepared, and then the molecular structure of the target product is gradually constructed through a series of reaction steps such as functional group conversion and the introduction of nitro and chlorine atoms. Although this approach is more complex, in some cases, it can be selected due to the availability of starting materials or the ease of control of reaction conditions.
When preparing 2-chloro-4-nitrotrifluorotoluene, each reaction step has a great impact on the purity and yield of the product. Minor changes in reaction conditions, such as temperature, pressure, catalyst dosage, etc., may cause the reaction results to vary greatly. Therefore, in actual production, it is necessary to repeatedly explore and optimize the reaction conditions to achieve the purpose of efficient and stable preparation of high-purity 2-chloro-4-nitrotrifluorotoluene.
What are the precautions in storage and transportation of 2-Chloro-4-Nitrobenzotrifluoride?
2-Chloro-4-nitrotrifluorotoluene is a chemical substance, and many matters should be paid attention to during storage and transportation.
Its properties are many and dangerous. When storing, the first thing to do is to choose a cool, dry and well-ventilated place. This is dangerous due to high temperature, humidity, or the change of its chemical properties. The warehouse temperature should be controlled within a specific range to prevent it from decomposing or triggering other chemical reactions due to excessive temperature.
Furthermore, it should be stored in isolation from oxidants, reducing agents, alkalis, etc. Due to the encounter of these substances, it is easy to cause severe chemical reactions, such as redox reaction, acid-base neutralization, etc., or the risk of fire or explosion. And the storage area must be clearly marked with warning signs to make everyone aware of its danger.
As for transportation, it must be packed in suitable packaging in accordance with relevant regulations. The packaging must be solid and well sealed to prevent leakage. During transportation, it should also be maintained smoothly to avoid bumps and vibrations to avoid damage to the packaging. Transportation vehicles should be equipped with corresponding emergency treatment equipment and protective equipment. In case of leakage, they can be disposed of in time. Transportation personnel should also be professionally trained to be familiar with the characteristics of this material and emergency measures.
All of these are for those who should pay attention when storing and transporting 2-chloro-4-nitrotrifluorotoluene. A little carelessness can cause disasters and endanger lives and property.