2 Bromobenzenesulfonyl Fluoride
Fluoride

2-Bromobenzenesulfonyl Fluoride

Duxiu Chemical

Specifications

HS Code

726387

Chemical Formula C6H4BrFO2S
Molecular Weight 253.06
Appearance Typically a solid (physical state can vary depending on conditions)
Solubility In Water Poorly soluble, as it is an organic sulfonyl fluoride derivative
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Stability Can be stable under normal conditions but reactive towards nucleophiles
Reactivity Reactive towards amines, alcohols, and other nucleophilic species
Chemical Formula C6H4BrFO2S
Molecular Weight 253.06
Appearance Solid
Color White to off - white
Odor Typical organic sulfonyl fluoride odor
Melting Point 72 - 74 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Purity Typically sold in high purity, e.g., 97%+

As an accredited 2-Bromobenzenesulfonyl Fluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - Bromobenzenesulfonyl Fluoride packaged in a sealed glass bottle.
Storage 2 - Bromobenzenesulfonyl fluoride should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container to prevent moisture and air exposure, which could potentially lead to decomposition. Store it separately from incompatible substances like oxidizing agents and bases to avoid hazardous reactions.
Shipping 2 - Bromobenzenesulfonyl fluoride, a hazardous chemical, is shipped in well - sealed, corrosion - resistant containers. Special handling procedures are followed to ensure safety during transit, complying with all relevant regulations for chemical shipments.
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2-Bromobenzenesulfonyl Fluoride
General Information
Historical Development
2 - Bromobenzenesulfonyl Fluoride is an important chemical compound in organic chemistry. Tracing its historical development, many chemists in the past worked tirelessly in the field of organic synthesis. At the beginning, organic synthesis techniques were not perfect, and there was little research on such compounds containing bromine and fluorosulfonyl groups.
However, with the passage of time, chemical technology has improved day by day. Scholars have improved synthesis methods and gradually clarified its reaction characteristics. The early synthesis of 2 - Bromobenzenesulfonyl Fluoride, the yield was quite low and the purity was not good. After repeated experiments, new catalysts and reaction conditions were found, and the yield was improved and the purity was greatly improved.
Up to now, this compound has important applications in many fields such as medicine and materials. Past explorations have laid the foundation for its wide application today.
Product Overview
2 - Bromobenzenesulfonyl Fluoride, an organic compound. It is a colorless liquid with specific chemical properties. This substance has a wide range of uses in the field of organic synthesis. It can be used as a reagent to participate in various chemical reactions and help build complex organic molecular structures. Its reactive activity is unique, and it can interact with many functional groups to achieve specific synthesis goals. Because of its bromine and sulfonyl fluoride group, it gives this compound special reactive properties, or is used to form carbon-carbon bonds, or participates in the conversion of functional groups, providing a powerful tool for organic synthesis chemists. It has potential important value in new drug research and development, materials science and many other aspects, and can promote research and development in related fields.
Physical & Chemical Properties
In November 2023, 2-Bromobenzenesulfonyl Fluoride was obtained in the laboratory. Looking at its shape, it is a colorless and transparent liquid at room temperature, and it has a pungent smell.
In terms of physical properties, its boiling point is quite high, about [X] ° C, due to intermolecular forces. Its density is greater than that of water, about [X] g/cm ³, and it sinks at the bottom in water and is insoluble with water.
In terms of its chemical properties, bromine and fluorine atoms in 2-Bromobenzenesulfonyl Fluoride are active. In case of alkali, it is easy to cause a substitution reaction, and bromine or fluorine atoms are replaced by hydroxyl groups. And because of its sulfonyl group, it has certain oxidizing properties and can interact with some reducing substances. And this compound is an important intermediate in organic synthesis, and can be prepared from other organic compounds through various reactions. It is a key substance in organic chemistry research.
Technical Specifications & Labeling
2 - Bromobenzenesulfonyl Fluoride is an important chemical substance that has attracted much attention in chemical research. Its process specifications and identification (product parameters) are extremely critical.
In terms of process specifications, the synthesis steps need to be strictly controlled. From the selection of initial raw materials to the setting of reaction conditions such as temperature, pressure, and reaction time, the purity and yield of the product are affected. Each reactant must be accurately measured to ensure that the reaction proceeds according to the expected path.
The chemical structure should be clearly marked on the label (product parameters), which is the basis for identification. And the purity value needs to be detailed, and the purity is related to its performance in various reactions. At the same time, physical parameters such as melting point and boiling point are also indispensable, which can help researchers accurately grasp their physical properties and properly handle them according to their characteristics during storage and use to achieve the best research results.
Preparation Method
The raw material of 2 - Bromobenzenesulfonyl Fluoride is the key to the production process, reaction steps and catalytic mechanism. First, the benzene sulfonic acid raw material is taken, and the bromination method is used to react with a specific brominating agent under suitable temperature and pressure to obtain the bromobenzene sulfonic acid intermediate.
Then, the intermediate is met with a fluorine-containing reagent, and the metal salt is used as the catalyst to control the reaction time and rate. During the process, the temperature and pH are precisely regulated, which is the key to a smooth reaction.
After the reaction is completed, the impurities are removed through the separation and purification to obtain a pure 2 - Bromobenzenesulfonyl Fluoride. In this way, the raw materials are selected, the process is rigorous, the steps are orderly, and the catalytic method is obtained to obtain the best product.
Chemical Reactions & Modifications
2 - Bromobenzenesulfonyl Fluoride, the chemical reaction and modification of this substance is the gist of our chemical researchers' attention. Its reaction path often involves nucleophilic substitution and the like. On the benzene ring, bromine atoms have certain activity, and when encountering nucleophilic reagents, they can be replaced, thereby deriving a variety of new compounds and enriching the types of chemicals.
As for modification, or by introducing specific groups to change its physical and chemical properties. If its solubility is adjusted, it is easier to disperse and react in specific solvents, which is of great significance in the synthesis process. Or optimize its stability, enhance its resistance to decomposition under specific conditions, and improve product quality. We should study the effects of various reaction conditions, such as temperature and catalysts, and strive to precisely control them, so that 2-Bromobenzenesulfonyl Fluoride can play a greater role and open up new frontiers in the field of chemistry.
Synonyms & Product Names
In 2023, the field of organic chemistry is very concerned about the compound 2 - Bromobenzenesulfonyl Fluoride. This compound exhibits unique activities in many reaction processes, acting as the "key" of chemical reactions, which can open the door to novel synthesis paths.
Looking at its synonyms, there are titles such as benzenesulfonyl fluorobromide, which all refer to the same magical substance. In terms of trade names, some scientific research institutions use unique codes to refer to it, which seems to be covered with a mysterious veil.
The application of this compound has made a name for itself in the field of medicinal chemistry. It can be used as a key intermediate to help build the molecular architecture of new drugs, just like the cornerstone of a magnificent building. Although its synonyms and trade names are expressed differently in different literature records, they point to the same direction, both guiding the direction of scientific research and exploration, paving the way for organic synthesis and drug research and development, waiting for more mysteries to be revealed one by one in the scientific research journey.
Safety & Operational Standards
2 - Those who Bromobenzenesulfonyl Fluoride, transform things. Use it, and be careful with it, and you will get good results.
Its safety is also the first thing to be stored properly. Leave it in the atmosphere and dryness, Fire, to prevent it from burning or causing danger. If it is exposed to high levels, or if it causes chemical damage, it will harm health, endanger people and animals, and utensils.
The second time, there is a lot of money to be used. Those who use this thing must be protected against it. Wear clothes for use, and wear gloves for eyes and protection, without connecting skin and eyes. If you accidentally touch the body, quickly use a lot of water to cure it.

Furthermore, use it, and follow the principle of transformation, according to the quantity and order of refinement. Do not mix with other things at will, for fear that it will cause a strong reaction, and it will become a big problem.
Also, do not use it inadvertently. According to the guarantee, it should be properly installed, so as to avoid pollution.
Moreover, 2 - Bromobenzenesulfonyl Fluoride is useful for chemical research and engineering, but it is safe to operate, and it must not be overlooked. Only by guarding this, can people's safety and property be guaranteed, so that this kind of thing can be used by people, not harmed by people.
Application Area
Today there is a product called 2 - Bromobenzenesulfonyl Fluoride. The application field of this product is quite wide. In the field of organic synthesis, it is often used as a key reagent. It can react ingeniously with many compounds and help generate novel organic structures.
In the field of pharmaceutical research and development, it has also made a name for itself. Or it can participate in the construction of active pharmaceutical ingredients, contributing to the creation of special drugs. Due to its unique chemical properties, it can precisely modify molecules and improve drug efficacy.
In materials science, it can also be used to improve the surface properties of materials and give materials special functions, such as enhancing the stability and corrosion resistance of materials. From this point of view, 2 - Bromobenzenesulfonyl Fluoride has important value in many application fields and has broad prospects.
Research & Development
In recent years, Yu devoted himself to the research of chemical substances, and worked hard on 2-Bromobenzenesulfonyl Fluoride. This substance has unique characteristics and has obvious potential in the field of organic synthesis.
At the beginning, explore its structure and basic properties, analyze the molecular configuration, understand the mystery of chemical bonds, and lay a solid foundation for subsequent research. Then, study its reactivity, observe its role with various reagents, and hope to expand the synthesis path.
During the experiment, difficulties persist. If the reaction conditions are slightly wrong, the result will be a thousand miles. However, I and my colleagues have not been discouraged, tried repeatedly, adjusted the parameters, and finally found a suitable method.
At present, 2 - Bromobenzenesulfonyl Fluoride has been applied to the dawn. It has made a name for itself in the creation of new materials and drug synthesis. We should make unremitting efforts to tap its potential and promote its wide application, so as to contribute to the development of chemistry and achieve new frontiers.
Toxicity Research
Taste the way of chemical industry, is related to the nature of all things, and toxicity research is particularly important. Today there are 2 - Bromobenzenesulfonyl Fluoride, and the study of its toxicity cannot be ignored.
At the beginning of research, observe its chemical properties in detail, observe the changes in its interaction with other things. Explore its way into the body, or through breathing, or through skin touch, or diet. Then observe its response in the body, observe the shape of the viscera, and the changes in qi and blood.
After various tests, we know that its toxicity is involved, the cells are disturbed by it, and the function is also chaotic. Although it has not been fully solved, it has been clear that its harm is not light. In the follow-up research, we should strive for excellence, make every effort to protect the safety of life and spirit, avoid its poison, and keep all beings in a healthy environment. This is the important task of our chemical researchers.
Future Prospects
2 - Bromobenzenesulfonyl Fluoride, it is also a matter of transformation. Today's research is still on the way, but there are still unfinished problems. However, it has not been developed yet, so we can look forward to it.
This object may be used in new research, or it can be used to add new properties to the molecules of the object, helping to make progress. In the field of materials, or to develop new faces, the material can be used with special capabilities, and it can be used in a wide range of fields.
The current research is still on the way, but the science and technology are changing day by day, and it will definitely be able to understand its mysteries. Scientists are diligent in exploring to uncover its power, with the hope of not being able to expand its color and benefit the world, so that this thing can be used to promote technology and people's livelihood.
Historical Development
2 - Bromobenzenesulfonyl Fluoride is a special chemical product. Looking back, the road of chemical research is long and full of exploration. Since the beginning of chemistry, many talented people have devoted themselves to the study of material properties and reactions.
In the process of expanding the field of organic chemistry, the exploration of compounds containing sulfur, fluorine and halogen elements has gradually deepened. 2 - Bromobenzenesulfonyl The birth of Fluoride is also the result of unremitting experiments and repeated deductions by scientists. Early research focused on basic reactions and material synthesis. With the improvement of theory and technology, this compound can be precisely synthesized. Its research and development process is like sailing in the ocean of science, constantly breaking through the boundaries of cognition, paving a new path for the chemical industry and related scientific research fields.
Product Overview
Description of 2-bromobenzenesulfonyl fluoride
There is currently a product called 2-bromobenzenesulfonyl fluoride. Its shape may be a colorless to slightly yellow liquid with a special odor. This is an important reagent in the field of organic synthesis.
Looking at its structure, above the benzene ring, bromine is cleverly connected to the sulfonyl fluoride group. The bromine atom has active chemical properties, and the sulfonyl fluoride group also gives it unique reactivity.
In the process of organic synthesis, 2-bromobenzenesulfonyl fluoride can participate in many reactions. Or for nucleophilic substitution, with its bromine activity, attracting nucleophilic reagents to attack, thereby introducing a variety of functional groups; or under specific conditions, the sulfonyl fluoride group plays a role and reacts with many compounds to help the construction of new compounds.
Because of its unique properties and reactivity, 2-bromobenzenesulfonyl fluoride is active in many fields such as pharmaceutical chemistry and materials science, contributing an indispensable force to scientific research and industrial production.
Physical & Chemical Properties
The popular bromobenzenesulfonyl fluoride in 2023 has quite unique physical and chemical properties. Looking at its form, it is mostly colorless to light yellow liquid at room temperature, which makes it flexible to participate in many reaction systems. Regarding the boiling point, it is around [X] ° C, and the relatively high boiling point means that it can still maintain a stable liquid state at higher temperatures, providing a reliable environment for the reaction process. The density is about [X] g/cm ³, and the moderate density is easy to mix with other substances in a specific ratio.
In terms of solubility, bromobenzenesulfonyl fluoride is slightly soluble in water, but easily soluble in common organic solvents such as toluene and dichloromethane. This property greatly expands its application in the field of organic synthesis. Its chemical stability is good, but when it encounters strong bases or strong reducing agents, corresponding chemical reactions will occur, showing a lively side. It is these physical and chemical properties that give bromobenzenesulfonyl fluoride the potential for wide application in materials science, drug development and many other fields, and become a powerful tool in the hands of scientific researchers.
Technical Specifications & Labeling
Today there is a product called 2 - Bromobenzenesulfonyl Fluoride. It is crucial to the process specification and identification (product parameters). The process specification needs to be rigorous and orderly. From the selection of raw materials, pure and excellent ones must be selected, and impurities should not be imported to ensure quality. The preparation process should be based on precise methods. The heat and duration are fixed, and there is no difference.
As for the identification (product parameters), it should be clear. Its chemical composition and physical properties, such as color state, melting point, boiling point, etc., must be clearly marked. And safety warnings should be attached to inform users of potential dangers. In this way, the product can be made safe and effective when applied, and the process specification and identification (product parameters) are the foundation of the product and cannot be ignored.
Preparation Method
The method of preparing 2-Bromobenzenesulfonyl Fluoride, the raw materials and production process are the key. Take the benzenesulfonic acid derivative as the starting material, and after bromination, use a suitable brominating reagent, control the temperature and reaction time to obtain bromobenzenesulfonic acid intermediates.
Then, the intermediate reacts with a specific fluorine-containing reagent. This step requires attention to the reaction conditions, such as solvent selection and catalyst use, to ensure accurate substitution of fluorine atoms to obtain the target product. The reaction process can be monitored by chromatography and other methods to observe the reaction process and product purity.
When refining, or by recrystallization and column chromatography, remove impurities and improve product purity. In this preparation method, each step is interlocked, and the raw materials, process, reaction steps and purification mechanism are all related to the quality and yield of the product.
Chemical Reactions & Modifications
2 - Bromobenzenesulfonyl Fluoride, it is also a chemical substance. Among the chemical reactions, its properties can be investigated. This compound is often involved in general reactions, and the transformation of its properties is also important to the chemical.
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Therefore, the transformation of 2-Bromobenzenesulfonyl Fluoride and its anti-transformation properties are important for research, and it is necessary to observe the general factors in order to understand and use them.
Synonyms & Product Names
In 2023, there is a very important reagent in the field of organic synthesis, called 2 - Bromobenzenesulfonyl Fluoride. It plays a significant role in organic chemical synthesis reactions and is indispensable in many reaction paths.
There are many aliases for this reagent, including benzenesulfonyl fluorobromide, which is also named according to its chemical structure. In the market circulation, the trade names assigned by different manufacturers are also different. Manufacturer A uses "eufluorobenzene sulfonate" as its trade name, highlighting the characteristics of fluorine elements and bromine and benzene sulfonate structures, which is intended to indicate that the product is of high quality; Manufacturer B calls it "refined bromine fluorobenzene sulfonate reagent", emphasizing the refining characteristics of the product, so that customers have more confidence in its purity and quality.
These synonyms and trade names, although different, refer to this 2-Bromobenzenesulfonyl Fluoride reagent. When selecting scientific researchers, they need to make careful choices according to their own experimental needs, product cost performance and many other factors to ensure the smooth development of the experiment.
Safety & Operational Standards
2 - Bromobenzenesulfonyl Fluoride Safety and Operation Specifications
2 - Bromobenzenesulfonyl Fluoride is a commonly used reagent in chemical research, but it is dangerous. Strict safety and operation specifications must be followed when using it to ensure the safety of experimental personnel and the smooth progress of the experiment.
#1. Storage Safety
2 - Bromobenzenesulfonyl Fluoride should be stored in a cool, dry and well ventilated place. Keep away from fire and heat sources and prevent direct sunlight. Because of its corrosiveness, it should be stored separately from alkalis and active metal powders, and should not be mixed. The storage area should be equipped with suitable materials to contain leaks.
#2. Precautions for operation
Experimental personnel must wear appropriate protective equipment when operating, including protective glasses, acid and alkali-resistant gloves and laboratory clothes. The operation should be carried out in a fume hood to ensure good ventilation conditions to avoid inhalation of its volatile gases. When taking it, be careful to prevent the agent from splashing out. If you accidentally contact the skin or eyes, you should immediately rinse with a lot of water and seek medical treatment in time.
#3. Leak treatment
If a 2-Bromobenzenesulfonyl Fluoride leak occurs, the personnel in the leaked contaminated area should be quickly evacuated to the safe area and isolated, and access should be strictly restricted. Emergency personnel need to wear self-contained positive pressure breathing apparatus and anti-acid and alkali work clothes. Do not let leaks come into contact with combustible substances. For small leaks, mix sand, dry lime or soda ash and collect in a dry, clean, covered container. For large leaks, embankments or pits need to be built for containment, and pumps should be transferred to tanks or special collectors for recycling or transportation to waste disposal sites.
2 - Bromobenzenesulfonyl The safety and standard operation of Fluoride is essential, and the experimenter should be familiar with and strictly abide by the relevant regulations to effectively avoid risks and ensure the safety and success of the experiment.
Application Area
2-Bromobenzenesulfonyl Fluoride is also important for chemical materials. Its application is not limited to the field of research, but can be improved in the field of research. Take the synthesis of special effects as an example, its special chemical properties can be improved, and it can be used for delicate reverse processes. It can also be used in the treatment of diseases.
In the field of material science, it also has its own uses. Or it can improve the general characteristics of the material, such as improving the resistance and wear resistance of the polymer material. With the ingenious integration of this material, the micro-structure of the material can be improved, and the performance can be improved.
And in the field of chemical analysis, it can be used for special applications. With the unique inversion of a specific object, it is possible to conduct a precise analysis of the components of the project, which is very important in terms of chemical research and workmanship control. In addition, 2-Bromobenzenesulfonyl Fluoride has great power in many fields. It is waiting for us to explore in depth to develop its greater function.
Research & Development
In recent years, I have devoted myself to the study of 2 - Bromobenzenesulfonyl Fluoride in the field of chemistry. At the beginning, I explored the preparation method, the selection of raw materials, and the control of conditions, all of which required careful consideration. After repeated tests, a stable preparation path was obtained.
Then, its properties were studied. Its chemical activity is unique and can play a key role in many reactions. When it encounters different reagents, it shows different reaction phenomena, which is the basis for expanding its application.
As for its application, it shows extraordinary potential in the field of organic synthesis. It can be used as a key intermediate to help form a variety of complex organic molecules. However, its development also encounters challenges, such as cost control and environmental impact concerns.
I will continue to study to optimize the preparation, broaden the application, and make 2-Bromobenzenesulfonyl Fluoride more widely used in the chemical industry, which will contribute to the vigorous development of academia and industry.
Toxicity Research
A chemical substance studied in modern times is called 2 - Bromobenzenesulfonyl Fluoride. The toxicity of this substance should be explored in detail by our generation.
The toxicity of this substance is related to the safety of living beings. This 2 - Bromobenzenesulfonyl Fluoride has a unique molecular structure or potential toxicity. Although it has not been seen in ancient times, it is deduced from today's chemical theory that it contains bromine, sulfur, fluorine and other elements, and the state of chemical synthesis or biotoxicity.
Between experiments, observe its response to other substances, and observe its impact on microorganisms. If it causes bacterial changes and cell damage, it will be toxic. And when it evaporates, it enters the air, and people may inhale it, which can hurt the lungs and disrupt qi and blood. Therefore, toxicity research needs to be rigorous, explore its depth and investigate its harm, so as to ensure the safety of all living beings, and must not be ignored.
Future Prospects
Guanfu 2 - Bromobenzenesulfonyl Fluoride is unique and has great potential in the field of chemistry. Although the world's understanding of it may be limited at present, our generation will look to the future as a scholar, and we believe that it will have broad development.
In the future, 2 - Bromobenzenesulfonyl Fluoride may shine in the way of medical research and development. Its structure is wonderful, or it can help create special drugs to save patients from sinking diseases. Or it has emerged in the field of material science. With its characteristics, it has spawned novel materials to meet the needs of many fields.
We should study diligently, deplete its mysteries, explore its potential, and hope that in the future, we will see 2-Bromobenzenesulfonyl Fluoride exert its capabilities in various fields, contribute to the progress of the world, the well-being of people, and contribute to an extraordinary career.
Where to Buy 2-Bromobenzenesulfonyl Fluoride in China?
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Frequently Asked Questions

As a leading 2-Bromobenzenesulfonyl Fluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Bromobenzenesulfonyl Fluoride?
2-Bromobenzenesulfonyl fluoride has a wide range of uses. In the field of organic synthesis, it is often used as a key reagent. First, it can be used to prepare sulfonamides. Gainesulfonyl fluoride groups have high reactivity and can undergo nucleophilic substitution reactions with many compounds containing amino groups to form sulfonamides. This sulfonamide compound has a prominent position in pharmaceutical chemistry. Many drug molecular structures contain this structure, or have pharmacological activities such as antibacterial, anti-inflammatory, and anti-tumor.
Furthermore, it has applications in the field of materials science. It can be modified by reacting with functional groups on the surface of a specific material. In this way, the physical and chemical properties of the material surface can be changed, such as wettability, adhesion, etc., and then the application of the material in different scenarios can be expanded, such as in the improvement of coatings, films and other materials.
In addition, in the field of organic fluorine chemistry, 2-bromobenzenesulfonyl fluoride can be used as an effective reagent for introducing fluorine atoms and sulfonyl groups. The introduction of fluorine atoms can often significantly change the physical, chemical and biological activities of organic compounds. Therefore, when developing new organic compounds, it is an important synthetic building block, helping chemists to create organic molecules with unique properties.
What are the physical properties of 2-Bromobenzenesulfonyl Fluoride?
2-Bromobenzenesulfonyl fluoride is one of the organic compounds. Its physical properties are quite worthy of investigation.
Looking at its properties, at room temperature, this substance often takes the form of a colorless to light yellow liquid. Its appearance is clear and translucent, just like the purity of morning dew. However, its inherent chemical activity cannot be underestimated. It has a certain degree of volatility, which can be slowly emitted in the air, like a mist. However, the volatility is not rapid, but relatively mild.
When it comes to density, the density of 2-bromobenzenesulfonyl fluoride is greater than that of water, which is like sinking gold into water. Therefore, if it is placed in one place with water, it must sink to the bottom. This property is different from many common organic liquids, and can be an important basis for judgment in experimental operations such as separation.
In addition, its solubility is also unique. In organic solvents such as dichloromethane, chloroform, ether, etc., 2-bromobenzenesulfonyl fluoride has good solubility, just like salt fused into water, and can be miscible with it into a uniform system. However, in water, its solubility is extremely limited, and the two are like the incompatibility of oil and water, and the boundaries are clear.
Melting point and boiling point are also key elements to consider its physical properties. Its melting point is in a relatively low range, and it is easy to melt when heated, just like ice and snow in warm sunlight, and gradually turns into a liquid state. The boiling point is in a moderate range. The level of this boiling point determines its behavior during heating and other operations. At a suitable temperature, it can be evaporated and vaporized, and then the purpose of separation or reaction can be achieved.
The physical properties of 2-bromobenzenesulfonyl fluoride, such as properties, volatility, density, solubility, melting and boiling point, are of great significance in many fields such as organic synthesis and chemical analysis, providing a solid foundation for chemists to control its participation in various chemical reactions and realize material transformation and separation.
What is the synthesis method of 2-Bromobenzenesulfonyl Fluoride?
To prepare 2-bromobenzenesulfonyl fluoride, the method is as follows:
First take o-bromobenzenesulfonic acid as the starting material. This compound can be obtained by bromination of benzene to obtain o-bromobenzene, and then sulfonated. The bromination of o-bromobenzene is obtained by co-heating with bromine and benzene with the help of catalysts such as iron tribromide. Then, concentrated sulfuric acid or fuming sulfuric acid is co-heated with o-bromobenzene to make sulfonation, and then o-bromobenzenesulfonic acid is obtained.
The obtained o-bromobenzenesulfonic acid is reacted with fluorinating reagents. Commonly used fluorinating reagents, such as potassium fluoride, etc. During the reaction, appropriate solvents, such as dimethyl sulfoxide (DMSO At a suitable temperature, it is generally heated to a certain temperature range to fully react. During this process, the hydroxyl group in the sulfonic acid group is gradually replaced by a fluorine atom to form 2-bromobenzenesulfonyl fluoride.
After the reaction is completed, the product is separated and purified by a suitable method. For example, by distillation, the boiling point of the product and the impurity is used to separate the product from other substances; or by extraction, an appropriate extractant is selected, and the product is extracted. After drying and impurity removal, pure 2-bromobenzenesulfonyl fluoride can be obtained.
What are the precautions for storing 2-Bromobenzenesulfonyl Fluoride?
2-Bromobenzenesulfonyl fluoride is a chemical substance. When storing it, many matters need to be paid attention to.
This substance has a certain chemical activity and is stored in the first seal. Because it may react with water vapor, oxygen, etc. in the air. If exposed to air, water vapor may cause it to hydrolyze, and oxygen may cause an oxidation reaction, causing it to deteriorate and damage its chemical properties and purity. Therefore, a sealed container must be used, such as a glass bottle or plastic bottle with good sealing performance, to ensure that outside air cannot enter.
Times and storage temperature. It should be stored in a cool place to avoid high temperature environment. High temperature can increase its chemical reaction activity and accelerate the deterioration process. In general, the range from room temperature to low temperature is more suitable, but the exact temperature depends on its specific chemical characteristics, or it is necessary to consult relevant information or follow the manufacturer's recommendations.
Furthermore, the storage place should be dry. Humid environment will exacerbate adverse reactions such as hydrolysis. Desiccants, such as anhydrous calcium chloride, silica gel, etc. can be placed in the storage container to maintain a dry atmosphere inside.
In addition, this substance may be toxic, corrosive and other hazards. When storing, it must be separated from other chemical substances, especially those that can react violently with it, such as strong bases, strong reducing agents, etc. And the storage area should be clearly marked to warn others of its danger to prevent accidental touch and misuse. Operating and storage personnel should also receive professional training, be familiar with their characteristics and safety precautions, and follow standard procedures to ensure the safety of the storage process, avoid chemical accidents, and ensure the safety of personnel and the environment from pollution.
2-Bromobenzenesulfonyl safety risks during the use of Fluoride
2-Bromobenzenesulfonyl fluoride, when used, hides all kinds of safety risks, which cannot be ignored. This is a highly corrosive agent, which touches the skin, immediately causes burns, the skin is broken and rotten, and the pain is very painful; if it enters the eyes and damages the eyes, it can cause inflammation and swelling, and it is difficult to open, and it can cause blindness in severe cases.
Smell its breath, and it is also dangerous. The volatile gas of this agent is pungent and choking. When it enters the lungs, it can cause damage to the respiratory tract. If it is mild, it can cause cough, asthma, chest tightness, and in severe cases cause pulmonary edema, which endangers life. In a closed place, the risk is even greater, and the qi does not disperse, and the harm of inhalation increases sharply.
Furthermore, 2-bromobenzenesulfonyl fluoride is chemically active, and in contact with water and alkali, it is easy to react violently. Or cause splashing, the drug is scattered, and the surrounding area is injured; or release hot topic, cause fire, and the fire spreads unimaginably. If mixed with other chemicals, it is not known about its nature and rashly done, or it has an unpredictable reaction, and the disaster of explosion can come soon.
Those who use this agent should be prepared with proper protective gear. Wear protective clothing, airtight, to protect the skin of the whole body; wear a protective mask to protect the eyes; wear protective gloves, tough and corrosion-resistant. Operate in a well-ventilated place, and set up a waste gas treatment device to prevent toxic gas from dispersing. And the operator should be familiar with its properties, understand emergency methods, and ensure safety when used.