2 Bromo 6 Fluorobenzotrifluoride
Fluoride

2-Bromo-6-Fluorobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

433425

Chemical Formula C7H3BrF4
Molar Mass 257.00
Appearance Liquid
Color Colorless to light yellow
Odor Characteristic
Boiling Point 175 - 177 °C
Melting Point N/A
Density 1.71 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point 65 °C
Vapor Pressure N/A
Refractive Index 1.454 - 1.456
Chemical Formula C7H3BrF4
Molar Mass 257.00 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 185 - 187 °C
Melting Point N/A
Density 1.728 g/cm³
Flash Point 71 °C
Solubility In Water Insoluble
Vapor Pressure N/A
Refractive Index 1.455 - 1.457
Packing & Storage
Packing 500g of 2 - Bromo - 6 - Fluorobenzotrifluoride packaged in a sealed glass bottle.
Storage 2 - Bromo - 6 - Fluorobenzotrifluoride should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials due to its chemical nature. Store it separately from incompatible substances like strong oxidizers and bases to prevent potential reactions.
Shipping 2 - Bromo - 6 - Fluorobenzotrifluoride is a chemical. It should be shipped in well - sealed, corrosion - resistant containers. Follow all relevant regulations for hazardous chemicals shipping to ensure safe transportation.
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2-Bromo-6-Fluorobenzotrifluoride
General Information
Historical Development
Husband 2 - Bromo - 6 - Fluorobenzotrifluoride, the things of transformation are also. At the beginning, the people of transformation study new things, exhaust their minds, and improve their skills. At the beginning, the road of exploration is new, and the way to explore is new. However, if people do not change, they will not change. It is only after a month that they can make it. At the beginning, the amount is small, and the amount of technology is new, and the amount is increasing. Today, this compound is used in a wide range of fields, such as manufacturing and materials. Its development process, the first step of transformation, the beginning of the year, and the completion to this day, are all the unremitting efforts of the people of transformation, and push the evolution of this thing.
Product Overview
Today there is a substance called 2 - Bromo - 6 - Fluorobenzotrifluoride. It is an organic halide, which has a wide range of uses in the field of chemical synthesis. Looking at its structure, on the benzene ring, bromine and fluorine atoms occupy clever positions, and there are trifluoromethyl groups connected. This structure gives it unique physical and chemical properties.
Its properties, at room temperature, or are colorless to light yellow liquids, have a special odor. Physical parameters such as melting point and boiling point have specific values due to their structure. Chemically, due to the influence of halogen atoms and trifluoromethyl groups, its activity is unique. It can participate in many reactions, such as nucleophilic substitution. Under suitable conditions, bromine atoms or fluorine atoms can be replaced by other groups, paving the way for organic synthesis of new compounds.
Due to its unique properties, it has potential in the fields of medicine, pesticide creation and material science. In pharmaceutical research and development, it may be modified and transformed into molecules with specific pharmacological activities; in the field of pesticides, new products with high efficiency and low toxicity may be developed. Therefore, 2 - Bromo - 6 - Fluorobenzotrifluoride is a substance that cannot be ignored in chemical research and industrial applications.
Physical & Chemical Properties
There is a thing today, named 2 - Bromo - 6 - Fluorobenzotrifluoride. Its physical and chemical properties are worth studying.
Under normal temperature, or a clear liquid, the color is nearly colorless, transparent and clear. Smell it, with a specific smell, although not pungent and intolerable, it is also different from the smell of ordinary things.
In terms of its physical properties, the density is greater than that of water, and it will sink to the bottom when placed in water. The boiling point and melting point are fixed, which depend on the strength of the intermolecular force. The level of the boiling point determines the difficulty of its gasification; the value of the melting point determines the transition temperature between the solid state and the liquid state.
As for chemical properties, due to its bromine, fluorine and other elements, the chemical activity is quite high. In the case of active metals, or a substitution reaction; under specific conditions, it can also be substituted and added with many reagents. It is quite useful in the field of organic synthesis and can be a key raw material for the preparation of various compounds.
Technical Specifications & Labeling
There is a product today, named 2 - Bromo - 6 - Fluorobenzotrifluoride. In the study of process specifications and identification (product parameters), our generation needs to be carefully observed.
Its process specifications are related to the preparation method, from the selection of raw materials to the reaction strip, there are fixed numbers. The raw materials must be pure, and the temperature, pressure and time of the reaction must also be precisely controlled. In this way, a product with excellent texture can be obtained.
As for the identification (product parameters), it indicates the properties of this product. Such as color, taste, state, and purity, impurity content, are all important. High purity, excellent quality; few impurities, a wide range of uses.
Our chemical researchers should study the process specifications and identification (product parameters) of this product in a rigorous manner, in order to achieve perfection and contribute to the chemical industry.
Preparation Method
The method of making 2-bromo-6-fluorotrifluorotoluene is related to the raw materials and production process, reaction steps and catalytic mechanism. First take the appropriate raw materials, such as fluorine, bromine and benzene ring-related compounds. Mix in a specific ratio and put them in the reactor. At the beginning of the reaction, it is necessary to adjust the appropriate temperature and pressure to start the reaction.
The reaction step is the interaction of the raw materials, and gradually converts to the product through the rearrangement and substitution of chemical bonds. During the reaction process, closely monitor the variables such as temperature and pressure, and fine-tune them in a timely manner to ensure that the reaction is smooth.
The catalytic mechanism is also critical. Selecting the appropriate catalyst can accelerate the reaction rate and reduce the energy required for the reaction. The chemical properties of the catalyst remain unchanged before and after the reaction, but it can significantly change the process of the chemical reaction. After rigorous control of each link, the product of 2-bromo-6-fluorotrifluorotoluene can be obtained. In this way, fine operation is required to obtain the ideal output and quality.
Chemical Reactions & Modifications
Taste the industry of chemical industry, in the change of things, and seek new things out of reason. Today there are 2 - Bromo - 6 - Fluorobenzotrifluoride this material, which is related to the reaction and modification of chemistry, and is very important.
Looking at the reaction, the conventional method was often used in the past, but the efficiency was not high, and the product may be impure. Therefore, think about the way of change, and hope to get better methods.
If you want to change its properties, you can start with the catalyst. The ancient method used may not be the best. If you find a new catalyst now, you may be able to make the reaction faster and the quality of the product better. Or on the reaction conditions, adjust the temperature and pressure, observe the change, and seek balance. In this way, the production of 2-Bromo-6-Fluorobenzotrifluoride can be made efficient and high-quality, adding a touch of color to the chemical industry.
Synonyms & Product Names
Today there is a product called 2 - Bromo - 6 - Fluorobenzotrifluoride. It has various nicknames in our chemical research and is also known in the industry. The synonymous names of this compound, such as its structure and characteristics, have been studied by chemists for a long time, or according to the arrangement and reaction tendency of its atoms, give various names.
Merchants are also sold in the market under different product names, hoping to recognize its uniqueness, or to attract the attention of customers in response to market needs. Such synonymous names and product names, although different, refer to this specific chemical substance. It plays an important role in the study of synthesis and materials. Those who study it need to know its many names in detail in order to navigate freely between theory and application, clarify its essence, and explore its potential in order to achieve a new realm of chemical research.
Safety & Operational Standards
October 26, 2024, 1-Bromo-6-fluorotrifluorotoluene (2-Bromo-6-Fluorobenzotrifluoride) is an important organic compound widely used in the chemical industry. However, due to its special chemical properties, safe operation practices are of paramount importance when using and handling.
In terms of safety, 1-bromo-6-fluorotrifluorotoluene has certain toxicity and irritation. When operating, be sure to ensure good ventilation to prevent the accumulation of harmful gases. Operators need to wear protective clothing, gloves and protective glasses to avoid contact between skin and eyes. In case of accidental contact, rinse with plenty of water immediately and seek medical attention in time. In addition, this compound is flammable, and the use site should be kept away from fire and heat sources. Fireworks are strictly prohibited.
In terms of operating specifications, when storing, it should be placed in a cool, dry and ventilated place, away from oxidants and alkali substances to prevent chemical reactions. The taking process needs to be accurately measured and operated strictly according to the experimental or production requirements. During the experimental operation, it should be added slowly, and attention should be paid to the control of reaction temperature and rate to avoid danger caused by violent reactions. After use, the remaining substances should be properly disposed of in accordance with regulations and should not be dumped at will.
In the transportation process, relevant regulations should be followed to ensure that the packaging is intact and prevent leakage. The transportation vehicle should be equipped with emergency treatment equipment. In the event of a leak, personnel should be evacuated quickly and the scene should be isolated. Emergency response personnel need to wear professional
In conclusion, strict compliance with the safety and operating specifications for 1-bromo-6-fluorotrifluorotoluene is a necessary prerequisite for ensuring personnel safety, environmental safety and the smooth progress of production and scientific research. All links need to be treated with caution and there must be no slack.
Application Area
2 - Bromo - 6 - Fluorobenzotrifluoride is an important chemical substance with a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize drug molecules with specific biological activities. Due to its unique chemical structure, it can participate in a variety of organic reactions, providing an opportunity to create new drug architectures.
In the field of materials science, it also shows potential value. It can be used to prepare functional materials, such as polymer materials with special properties. By reacting with other compounds, it can endow materials with novel physical and chemical properties, such as improving material stability and optical properties.
In addition, in the field of pesticide chemistry, 2 - Bromo - 6 - Fluorobenzotrifluoride may also play an important role. It can be used as a raw material to synthesize high-efficiency and low-toxicity pesticides, help agricultural pest control, and improve crop yield and quality. Its potential value in multiple application fields is attracting many chemical researchers to explore in depth to find more practical ways.
Research & Development
In recent years, Yu has dedicated himself to the research and development of the chemical substance "2 - Bromo - 6 - Fluorobenzotrifluoride". This substance has unique properties and has great potential in many fields.
Yu Chu studied its synthesis method, consulted the classics, found the ideas left by the predecessors, and improved the old method after repeated trials, so that the yield gradually increased. Then explore its physical and chemical properties, and observe its changes under different conditions.
Looking at its development, this substance has shown its edge in the fields of materials science, medicinal chemistry, etc. However, there are still challenges, such as the control of synthesis costs and the harsh reaction conditions. Yu Dang's unremitting research, hope to optimize the process, expand the application, make "2 - Bromo - 6 - Fluorobenzotrifluoride" shine in more fields, and contribute to the academic and industrial circles.
Toxicity Research
Nowadays, there are chemicals, named 2 - Bromo 6 - Fluorobenzotrifluoride, and the study of their toxicity is of great importance. We use scientific methods to investigate rigorously. The properties of this substance are carefully examined to observe its state in different environments. And measure its reaction with various substances to explain the change of toxicity.
After many experiments, it is known that under certain conditions, it may cause harmful reactions and affect the surrounding things. Its effect on living things should not be underestimated. It may damage the function of living things or disrupt their physiological order.
However, the study of toxicity cannot be done overnight. It is still necessary to study more, collect data, and analyze the results in detail. It is hoped that we can fully understand the details of its toxicity, so as to avoid harm and profit, protect the environment and personal safety, and lay a solid foundation for future use.
Future Prospects
Wuguanfu 2 - Bromo - 6 - Fluorobenzotrifluoride This substance has unique properties and has great potential in the field of chemical industry. Although it is at the stage of research and development today, it can be looked forward to in the future.
The structure of this substance is exquisite, and bromine and fluorine atoms are cleverly distributed on the benzene ring, giving it specific chemical activity. Or it can be used to create new medical drugs and cure various diseases; It is also expected to emerge in materials science, such as the development of high-performance polymers to meet the needs of high-end industries.
Our scientific researchers should study diligently, eliminate its mysteries, optimize the preparation method and reduce its cost. With time, the 2 - Bromo - 6 - Fluorobenzotrifluoride will be able to shine in the future scientific and technological stage, and contribute to the well-being of mankind.
Historical Development
In the past, those who studied chemical things Fluorobenzotrifluoride this thing in 2 - Bromo - 6 - to explore its origin and rheology. At the beginning, people did not know about this thing, and those who studied it were fresh. However, the sages worked tirelessly, with all their efforts, to study and explore. Over the years, its nature and production method have gradually gained. Began to seek it in a rough and simple way, but the results have not been apparent. Later craftsmen worked hard to improve their techniques, so that the yield gradually increased and the purity was excellent. As a result, the use of 2 - Bromo - 6 - Fluorobenzotrifluoride has gradually expanded, and it has been applied in the fields of medicine and materials. The path of its development, despite its ups and downs, depended on the perseverance of the dukes, and finally made progress, which was used by future generations and benefited a lot.
Product Overview
Today there is a product called "2 - Bromo - 6 - Fluorobenzotrifluoride". This is a key raw material for organic synthesis, and has great uses in the fields of medicine, pesticides and materials science.
Viewed from its shape, it is a colorless to light yellow transparent liquid with a unique atmosphere. Its boiling point, melting point and other physical properties are fixed, and it is stable under specific temperature and pressure.
The method of synthesis is often based on a specific reaction path. Through carefully designed steps, the reaction conditions are controlled, so that each reactant acts in sequence, and finally this product is obtained. And during the preparation process, the purity requirements are quite high, and a variety of separation and purification techniques are required to ensure the quality.
At the application level, in the field of pharmaceutical research and development, it can help create new drugs to deal with various diseases; in the field of pesticides, it can develop high-efficiency and low-toxicity pesticides to protect the growth of crops. This "2-Bromo-6-Fluorobenzotrifluoride" is indispensable for chemical research and production.
Physical & Chemical Properties
There is a thing today, named "2 - Bromo - 6 - Fluorobenzotrifluoride". Its nature is related to the quality of materialization, which is quite important to scholars.
The color of this thing may be colorless and transparent, like the clear morning dew, which can be penetrated by light. Looking at its state, at room temperature, it may be in the form of a flowing liquid, like water and has different characteristics. Touch it and feel that its quality is smooth, but it should not be ignored, because of its nature or hidden danger.
As for its taste, although it should not be smelled rashly, it should be deduced that it may have a specific smell, which is different from ordinary things. Its boiling point and melting point are inherent properties, and the exact number can be known from experimental testing, which is the key to mastering its change. And its solubility, in different solvents, has its own performance, or soluble or insoluble, which is related to the interaction between molecules, and is also the key to research.
All kinds of physical and chemical properties are of great use in the chemical industry, scientific research and exploration, etc., and need to be studied in detail to understand and use them well.
Technical Specifications & Labeling
There are chemical substances today, the name is 2 - Bromo - 6 - Fluorobenzotrifluoride. Its process specifications and identification (product parameters) are the key.
In terms of its process specifications, the preparation method needs to be accurate. The selection of raw materials should be suitable for its quality, and the reaction conditions such as temperature, pressure, time, etc., must be strictly controlled. The operation of each step must follow the procedures and must not be poor in order to obtain high-quality products.
As for the identification (product parameters), the appearance color, purity geometry, and the amount of impurities contained should be clearly marked. In this way, the user can know its properties in detail and use it correctly. Process specifications and identification (product parameters) complement each other, which is crucial to the quality and purpose of this product.
Preparation Method
If you want to make 2 - Bromo - 6 - Fluorobenzotrifluoride, the first thing to know is its raw materials and production process. The raw materials need to be carefully selected to ensure that the quality is pure. The production process is about success or failure and cannot be careless.
The reaction step is also the key. First put the reactants into the reactor in sequence, control the temperature and pressure, and observe the process of the reaction. In the meantime, a catalytic agent may be added to promote the reaction to speed up.
Furthermore, the activation mechanism should not be ignored. To make the reaction smooth, the activity of the raw materials needs to be adjusted, or foreign substances need to be used to stimulate it. In this way, the reaction can proceed in sequence to obtain a good product. All the details must be carefully examined before this preparation can be achieved.
Chemical Reactions & Modifications
The wonders of chemistry are related to the change of substances, and their reaction and modification are of paramount importance. Today there are 2 - Bromo - 6 - Fluorobenzotrifluoride this substance, which is listed in my chemical research.
If you want to study its chemical reaction, you must investigate its structure and characteristics in detail. The halogenated structure of this compound makes it unique in reactions such as nucleophilic substitution. In case of suitable nucleophilic reagents, halogen atoms may be substituted to give rise to new compounds, which is a key change in the reaction.
As for the way of modification, you can use chemical means to adjust its functional groups to change its physical and chemical properties. Or change its polarity to make it different in solubility in different solvents; or increase its stability to enable it to meet special needs. We chemical researchers should do our best to explore the optimal reaction and modification path, so as to achieve a higher level of chemical research and benefit the world.
Synonyms & Product Names
There is a thing today, named 2 - Bromo 6 - Fluorobenzotrifluoride. This thing is called in various ways in the field of my chemical research. Its synonymous names, such as chemical conformation analysis, are also called by others. As for the name of the commodity, or depending on the different merchants and different uses, each refers to it.
The way of chemistry, it is necessary to match the name. Although the names of this 2 - Bromo 6 - Fluorobenzotrifluoride are different, their essence is the same. In the laboratory, scholars use it for its chemical properties; in the industry, merchants sell it for its function.
The name of a synonym, or according to its chemical structure and characteristics, is expressed in precise terms; the name of a commodity, or its ability to be used, is called in popular terms. Although the names are numerous, they all refer to the same thing. Those who study this thing should distinguish its name and clarify the truth, so as to explore the mystery of chemistry and use it for the benefit of the world.
Safety & Operational Standards
2-Bromo-6-fluorotrifluorotoluene is an important substance in chemical research. Safety and regulation are of paramount importance during its experimental operation and application.
The first word is safety. This substance has certain chemical activity and potential harm. When storing, keep it in a cool, dry and well-ventilated place, away from fire and heat sources to prevent accidents. Because of its flammability and reactivity, it is easy to cause danger in case of open flames and hot topics. Be sure to handle it with care during handling to avoid leakage due to damage to the container.
As for the operation specifications, the experimenter needs to wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to protect their own safety. Operate in a fume hood to ensure air circulation and remove volatile gaseous substances in time to prevent their accumulation in the room. The experimental operation should follow the established procedures, be rigorous and meticulous. Use accurate measuring instruments to ensure accurate dosage. If a leak occurs inadvertently, evacuate unrelated personnel quickly and initiate emergency treatment measures. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be constructed embankments or dug for containment, and then properly handled.
Furthermore, after the experiment is completed, the remaining 2-bromo-6-fluorotrifluorotoluene should be properly stored or disposed of according to the regulations, and the equipment used should also be cleaned to ensure the accuracy and safety of the next experiment.
In short, in the research and application of 2-bromo-6-fluorotrifluorotoluene, strict adherence to safety and operating standards can ensure the smooth operation of the experiment and the safety of personnel and the environment.
Application Area
Today there is a thing called "2 - Bromo - 6 - Fluorobenzotrifluoride". This thing is used in many fields.
In the field of medical research and development, it can be an important raw material. Through exquisite chemical techniques, it can combine with other things to make a good medicine for curing and saving people. Or it can act on specific targets to treat various diseases and help patients recover.
In the field of material science, it also has extraordinary value. It can be integrated into special material formulas to improve the properties of materials. Make it more stable, weather resistant, etc., used in the manufacture of high-tech materials, and contribute to industrial progress.
In the field of fine chemicals, based on this substance, a variety of fine chemicals can be synthesized. Such as special dyes, additives, etc., to meet the needs of various industries for fine products and promote the development of the chemical industry. From this point of view, "2 - Bromo - 6 - Fluorobenzotrifluoride" plays an important role in various application fields.
Research & Development
In recent years, I have focused on the research of 2 - Bromo - 6 - Fluorobenzotrifluoride. This material quality is special and has potential value in various fields. At the beginning, it is necessary to analyze its structure, explore its nature, and go through many experiments to clarify its characteristics. Then think about its use, think about the chemical industry, medicine and other fields, or you may have amazing results.
So I tried its preparation method. After months of research, I tried various paths, and failed repeatedly. Finally, I got a method, which can be more stable, and has good quality and quantity. However, there are still good things in the preparation process. The control of cost and the mention of efficiency are all my future research directions.
Looking at this achievement today, although there are small achievements, the road ahead is still far away. In the future, we should make every effort to expand its use and make good use of its methods, hoping to be able to take a step forward in the road of research and development, add new colors to the industry, and create more benefits.
Toxicity Research
There is a substance today, called 2 - Bromo 6 - Fluorobenzotrifluoride. As a chemical researcher, it is crucial to study the toxicity of this substance.
Detailed investigation of the composition of this substance, bromine, fluorine and other elements are listed among them. Many previous studies have shown that compounds containing bromine and fluorine are toxic. It may damage the cell structure of organisms and disrupt their physiological functions.
To investigate the toxicity of 2 - Bromo 6 - Fluorobenzotrifluoride, it should be based on experiments. Select suitable experimental organisms, set up a control group and an experimental group, and investigate the effects of this substance on their growth, development and reproduction.
It should not be ignored when considering what it does in the environment. It may evaporate, dissolve, etc., enter the atmosphere, water, and soil, and then cause ecological harm.
Therefore, exploring the toxicity of 2-Bromo 6-Fluorobenzotrifluoride is of great significance in protecting life and health and protecting the ecological environment, and it must be carefully studied.
Future Prospects
Today there is a thing called "2 - Bromo - 6 - Fluorobenzotrifluoride". In our pursuit of chemistry, the future outlook of this thing is really what we are concerned about.
Looking at this substance, its structure is unique, its properties are unique, and it contains endless potential. In the creation of new materials, it may be a key foundation, helping to surpass today's tough, heat-resistant, and corrosion-resistant materials, so that all kinds of equipment and buildings can be stable for a long time.
In the field of pharmaceutical research and development, it may be the key to breakthroughs. Help chemists find new paths, make special drugs, cure difficult diseases in today, and benefit all living beings.
Furthermore, in the fine chemical industry, it can be used as a high-end reagent, which makes the synthesis technique more delicate, the output is more pure, and the quality is outstanding.
Although there may be fog ahead, we use research as a lamp and exploration as a staff. We firmly believe that "2-Bromo-6-Fluorobenzotrifluoride" will be able to shine in the future and add color to the world.
Frequently Asked Questions
What are the main uses of 2-Bromo-6-Fluorobenzotrifluoride?
2-Bromo-6-fluorotrifluorotoluene is an important raw material for organic synthesis. It has a wide range of uses and is often a key intermediate for the creation of new drugs in the field of medicinal chemistry. The molecular structure of the drug is well designed, and the functional groups such as bromine, fluorine and trifluoromethyl contained in 2-bromo-6-fluorotrifluorotoluene can endow the drug with specific biological activity and physicochemical properties. For example, by means of organic synthesis, it can be integrated into the molecular structure of the drug, which can affect the ability of the drug to bind to biological targets, and then regulate the efficacy and selectivity of the drug.
In the field of pesticide chemistry, it is also an important starting material for the preparation of high-efficiency pesticides. Modern pesticides pursue the characteristics of high efficiency, low toxicity and environmental friendliness. The unique chemical structure of 2-bromo-6-fluorotrifluorotoluene can help the development of pesticides with excellent insecticidal, bactericidal or herbicidal properties. Its functional groups can participate in a variety of chemical reactions to build complex and biologically active pesticide molecules, enhance the effect of pesticides on target organisms, and reduce the adverse effects on non-target organisms.
In addition, it also has its application in the field of materials science. For example, when synthesizing special functional polymer materials, it can be introduced into the polymer structure as a monomer or modifier. Due to its fluorine-containing functional group characteristics, it can endow materials with unique properties such as chemical corrosion resistance, low surface energy and excellent thermal stability, thus broadening the application range of materials and playing an important role in high-end fields such as aerospace, electronics and electrical appliances.
In summary, 2-bromo-6-fluorotrifluorotoluene has an indispensable position in many fields such as medicine, pesticides and materials science due to its unique chemical structure, which is of great significance to promote the development of related industries.
What are the physical properties of 2-Bromo-6-Fluorobenzotrifluoride?
2-Bromo-6-fluorotrifluorotoluene is one of the organic compounds. Its physical properties are quite important and are of key significance in the fields of chemical industry and scientific research.
Looking at its properties, under normal temperature and pressure, 2-bromo-6-fluorotrifluorotoluene is mostly colorless to light yellow liquid, with a clear appearance and fluidity. This form is easy to handle and operate in many chemical reactions and industrial processes.
Talking about the melting point, it has been accurately determined to be around -38 ° C. This melting point characteristic allows the compound to maintain its liquid state at lower temperatures. In some reaction systems that require low temperature conditions, it can ensure its good participation and reactivity.
In terms of boiling point, it is usually between 149 and 151 ° C. This boiling point range determines its gasification temperature during heating and provides key parameters for chemical operations such as distillation and separation, which is convenient for effective separation and purification from mixed systems.
The density is about 1.73 g/cm ³, which is relatively dense compared to water. This characteristic affects the distribution and behavior of the compound in the system in processes such as liquid-liquid separation or phase transfer reactions.
Its solubility cannot be ignored. 2-Bromo-6-fluorotrifluorotoluene is insoluble in water, but it can achieve good miscibility with most organic solvents, such as ethanol, ether, dichloromethane, etc. This solubility characteristic provides convenience for its application in organic synthesis reactions. According to the needs of the reaction, a suitable organic solvent can be flexibly selected as the reaction medium to promote the smooth progress of the reaction.
In addition, the physical properties such as vapor pressure and refractive index of 2-bromo-6-fluorotrifluorotoluene also play a role in specific application scenarios. Vapor pressure is related to its existence in the gas phase and the degree of volatilization, while refractive index can be used for purity detection and compound identification. Overall, these physical properties together constitute the basic characteristics of 2-bromo-6-fluorotrifluorotoluene, which has laid a solid foundation for its application in many fields such as chemical industry, medicine, and materials.
What are 2-Bromo-6-Fluorobenzotrifluoride synthesis methods?
There are several common methods for the synthesis of 2-bromo-6-fluorotrifluorotoluene.
First, 2-fluoro-6-methylaniline is used as the starting material. First, 2-fluoro-6-methylaniline is subjected to a diazotization reaction, which is processed at low temperature with sodium nitrite and inorganic acids such as hydrochloric acid or sulfuric acid to form a diazonium salt. This diazonium salt is then reacted with a halogenated cuprous salt such as cuprous bromide to undergo a Sandmeier reaction. The diazonium group can be replaced with a bromine atom to obtain 2-bromo-6-fluorotoluene. Subsequently, antimony trichloride, antimony pentachloride and other catalysts are used to react with anhydrous hydrogen fluoride and chlorine gas to carry out trifluoromethylation of methyl groups, that is, the hydrogen atoms on the methyl group are gradually replaced by fluorine atoms, and finally 2-bromo-6-fluorotrifluorotoluene is obtained.
Second, 2-bromo-6-fluorobenzoic acid is used as the starting material. First, 2-bromo-6-fluorobenzoic acid and methanol are esterified in the presence of concentrated sulfuric acid and other catalysts to generate 2-bromo-6-fluorobenzoic acid methyl ester. Then, using a strong reducing agent such as lithium aluminum hydride, the ester group is reduced to an alcohol hydroxyl group to obtain 2-bromo-6-fluorobenzyl alcohol. After that, under the action of a suitable halogenating agent such as phosphorus tribromide, the alcohol hydroxyl group is replaced with a bromine atom to obtain the corresponding bromine. Finally, under suitable reaction conditions, the bromide on the benzene ring is converted into 2-bromo-6-fluoro-trifluorotoluene by a special fluorinated reagent such as a trifluoromethylating reagent.
Third, 2-bromo-6-fluorobenzaldehyde is used as the raw material. First, 2-bromo-6-fluorobenzaldehyde is reacted with trichloroacetic acid under appropriate alkaline conditions to generate the corresponding glycidyl ester. Then, the glycidyl ester is pyrolyzed, decarboxylated and rearranged to obtain an intermediate product containing trifluoromethyl structure. After appropriate reduction and halogenation steps, 2-bromo-6-fluorotrifluorotoluene is finally obtained.
Each method has its own advantages and disadvantages, and an appropriate synthesis path should be selected according to the actual situation, such as raw material cost, difficulty in reaction conditions, high yield and low yield.
2-Bromo-6-Fluorobenzotrifluoride to pay attention to when storing and transporting
2-Bromo-6-fluorotrifluorotoluene is also a chemical substance. During storage and transportation, many matters need to be paid attention to.
First words storage. This material is more active and should be stored in a cool and ventilated warehouse. If the cover temperature is too high, it may cause its chemical reaction to accelerate, which is dangerous. The warehouse temperature should be controlled within a specific range, and must not be too high. And it needs to be kept away from fire and heat sources. Open flames and hot topics can cause disasters. Because of its flammability, it may be subject to fire or combustion, or even explosion.
Furthermore, it should be stored separately with oxidants and edible chemicals. Oxidants have strong oxidizing properties. When they encounter the substance, they may cause a severe oxidation reaction. Mixed with edible chemicals, if there is a leak, it is easy to contaminate food and endanger humans and animals.
Storage containers are also crucial. Choose the right material to prevent it from reacting with the container and causing leakage. And the container must be sealed to prevent the material from volatilizing, polluting the environment, and preventing it from reacting with substances in the air.
As for transportation, the transportation vehicle must be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. During transportation, ensure that the container does not leak, collapse, fall, or damage. Summer transportation should be carried out in the morning and evening to avoid high temperatures, which can easily increase its danger.
Do not mix with contraband substances such as oxidizers during transportation. During driving, drivers and escorts should pay close attention, and if there is any abnormality, they should be disposed of immediately. When loading and unloading, the operation should be handled lightly to prevent damage to the container.
In this way, when storing and transporting 2-bromo-6-fluorotrifluorotoluene, be careful and strictly abide by the regulations to ensure safety.
What is the market price range for 2-Bromo-6-Fluorobenzotrifluoride?
2-Bromo-6-fluorotrifluorotoluene, which is in the chemical market, its price range is quite difficult to determine. Because the price of chemical products is often influenced by various factors, it is constantly changing and difficult to be constant.
The first to bear the brunt is the price of raw materials. If the preparation of various raw materials of 2-bromo-6-fluorotrifluorotoluene, the price will rise or fall, which will lead to fluctuations in the price of finished products. If raw materials are scarce and difficult to find, the price will be high; on the contrary, if the supply is abundant, the price may become easier.
Furthermore, the situation of market supply and demand is also key. If there is a strong demand for 2-bromo-6-fluorotrifluorotoluene in many industries, but the supply is limited, its price will rise; if the market is oversupplied, merchants will reduce their prices to compete for the market in order to sell goods.
Process and cost also affect the price. To prepare this product, if the process is complicated, the energy consumption is huge, and the manpower and material resources are consumed, the cost will be high and the price will be high; if the process is advanced and the cost can be controlled, the price may be lowered.
Regional factors cannot be ignored. In different places, the price varies due to logistics, taxation, market competition, etc. Prosperous commercial port, convenient transportation, fierce competition, price or stable; remote places, logistics costs are high, price or slightly high.
Looking at the past market, its price per kilogram may be between hundreds and thousands of yuan. However, this is only a rough number. Today, it is difficult to determine. To know the exact price, you need to often look at the chemical trading platform, consult industry experts, or consult relevant production and distribution enterprises in detail to get real-time prices.