Chemical Formula | C7H3BrF3NO2 |
Molar Mass | 270.003 g/mol |
Appearance | Typically a colorless to pale yellow liquid |
Boiling Point | Approximately 228 - 230 °C |
Density | Data may vary but around 1.7 - 1.8 g/cm³ |
Solubility | Sparingly soluble in water, soluble in common organic solvents like dichloromethane, chloroform |
Vapor Pressure | Low vapor pressure at room temperature |
Flash Point | Relatively high, as it's a less volatile liquid |
Stability | Stable under normal conditions, but can react with strong oxidizing and reducing agents |
What are the main uses of 2-bromo-5-nitrotrifluorotoluene?
2-% -5-guanidinotriacetamide is a special chemical compound, and its main purpose is to use it.
In this field, this compound has demonstrated its effectiveness. It may be used in the synthesis of specific compounds. Due to its special chemical properties, it can be used to synthesize and react to multiple compounds, and it can be cleverly synthesized to produce molecules with therapeutic properties. For example, in the research of certain diseases, 2-% -5-guanidinotriethylamine can be used to form a series of reactions, forming active ingredients that can act on specific diseases, helping to improve the effectiveness of chemicals and providing effective means for the treatment of diseases.
In the field of materials, it can also be used. It can be used to improve the properties of certain materials. For example, it can be added to a specific polymer material, or it can change the physical properties of the material, such as increasing the properties and quality of the material. Its molecules can interact with the molecules of the polymer material to form specific chemical or physical forces, which can improve the overall properties of the material and meet the special needs of material properties in different domains.
In addition, in chemical research, 2-% -5-guanidinotriacetamide is also an important research phenomenon. Scientists can expand the boundaries of chemical knowledge through in-depth exploration of its chemical properties and anti-scientific research, explore new types of chemical solutions, provide new ideas and directions for the development of chemical technologies, and promote the integration of the field.
What are the physical properties of 2-bromo-5-nitrotrifluorotoluene?
2-% -5-Cyanotrifluorotoluene is an important compound in organic chemistry. Its physical properties are quite unique and it has applications in many fields.
This compound is mostly liquid at room temperature, with a clear and transparent appearance, like a quiet water, with a shimmer in the flow. Its boiling point is in a specific range, about [X] ° C. This property allows it to realize gas-liquid conversion at the corresponding temperature during heating or distillation operations, which helps to separate and purify. The melting point is [X] ° C. When the temperature drops to this point, it will solidify from liquid to solid, just like water condenses into ice, and the shape changes significantly.
2-% -5-cyanotrifluorotoluene has a density slightly higher than that of water. When placed in water, it will sink like a stone. And because of its fluorine-containing atoms, it has certain chemical stability and hydrophobicity. It is like wearing a layer of protective armor, which is not easy to blend with water, and its solubility in water is extremely low.
Its vapor pressure cannot be ignored. At a certain temperature, some molecules will escape from the liquid surface to form steam. The size of the vapor pressure is closely related to the temperature. As the temperature increases, the thermal motion of the molecules intensifies, and the molecules escaping from the liquid surface increase, and the vapor pressure increases accordingly. This property needs to be taken into account when storing and using the compound. If the vapor pressure is too high, the storage container needs to have good sealing and pressure resistance to prevent leakage.
In terms of odor, it exudes a special smell. Although it is not pungent or unpleasant, it is also unique and recognizable, which seems to be a unique "logo" given to it by the chemical world.
In summary, the physical properties of 2-% -5-cyanotrifluorotoluene lay the foundation for its application in organic synthesis, drug development and other fields. Chemists can skillfully design experiments according to its characteristics to achieve the expected chemical transformation, and contribute to the development of many fields.
What are the chemical properties of 2-bromo-5-nitrotrifluorotoluene?
2-%-5-cyanotrifluorotoluene is one of the organic compounds. It has unique properties and has its functions in many fields.
This substance has certain chemical activity. From its structural point of view, the presence of hydroxyl groups (-OH) gives it a certain hydrophilicity. Hydroxyl groups can participate in various chemical reactions, such as esterification reactions, and can interact with acids to form corresponding ester compounds. In this process, the hydrogen atom of the hydroxyl group is replaced by acid groups. And the hydroxyl group easily forms coordination bonds with metal ions, showing certain complexing properties.
The characteristics of cyano (-CN) should not be underestimated. Cyanyl groups have strong polarity, which increases the dipole moment of molecules and affects their physical properties, such as boiling point and solubility. Cyanyl groups can undergo hydrolysis reactions, and under appropriate conditions, they can be converted into carboxylic groups (-COOH), and then a series of carboxylic acid compounds can be derived. This reaction is very important in organic synthesis.
Furthermore, the introduction of trifluoromethyl (-CF 🥰) gives the compound unique physical and chemical properties. Trifluoromethyl has strong electron absorption, which can change the electron cloud density distribution of molecules, affecting the reactivity and stability of molecules. Because of its strong electron absorption effect, it can enhance the polarity of adjacent chemical bonds, making it easier for atoms connected to it to participate in nucleophilic or electrophilic reactions. At the same time, the presence of trifluoromethyl significantly enhances the fat solubility of the compound, which affects its absorption, distribution and metabolism in vivo.
The synergistic effect of 2-% -5-cyanotrifluorotoluene these functional groups has potential application value in the fields of medicine, pesticides and materials science. In the field of medicine, it can be used as a lead compound through structural modification and optimization to develop new drugs; in the field of pesticides, with its special chemical properties, it can develop high-efficiency and low-toxicity pesticide varieties; in the field of materials science, it can be used to prepare polymer materials with special properties, such as fluoropolymers, to meet specific material requirements.
What is the preparation method of 2-bromo-5-nitrotrifluorotoluene?
To prepare 2-hydroxyl-5-aminotrimethylbenzene, the method is as follows:
First take trimethylbenzene as the starting material, and nitrate it at a suitable temperature with a mixed acid of concentrated sulfuric acid and concentrated nitric acid. In this step, attention should be paid to the ratio of mixed acid and the control of the reaction temperature. If the temperature is too high, it is easy to cause side reactions such as polynitroylation. After the reaction is completed, nitrotrimethylbenzene is obtained by washing with water, alkali washing, drying, etc.
Then nitrotrimethylbenzene is reduced. A suitable reducing agent can be used, such as a system of iron powder and hydrochloric acid, or hydrogen reduced in the presence of a catalyst. If iron powder and hydrochloric acid are used, attention should be paid to the amount of iron powder and the reaction time, and the iron mud needs to be properly handled after the reaction. When reducing with hydrogen, the activity and selectivity of the selected catalyst are very critical. Commonly used catalysts such as palladium carbon, etc. After the reduction reaction, the nitro group is converted to an amino group to obtain 5-aminotrimethylbenzene.
Subsequently, a hydroxyl group is to be introduced. 5-aminotrimethylbenzene can be salted with sulfuric acid first to protect the amino group from being affected in the subsequent reaction. Then a suitable halogenating agent, such as chlorine, is used under the action of light or an initiator to halogenate a specific position on the benzene ring and introduce halogen atoms. Then treated with alkali solution, the halogen atom is replaced by a hydroxyl group. After hydrolysis, the target product 2-hydroxy- 5-aminotrimethylbenzene is obtained. Finally, the pure product is obtained through separation and purification steps, such as recrystallization, column chromatography, etc. Throughout the preparation process, the conditions of each step of the reaction are controlled, and the separation and identification of intermediates are all crucial. Careful operation is required to effectively obtain this compound.
What are the precautions for storing and transporting 2-bromo-5-nitrotrifluorotoluene?
2-% -5-Cyanotrifluoroacetyl aniline is a chemical substance. If it is stored in a hot place, it is necessary to pay attention to the following general things:
First, the storage environment is very important. It is advisable to create a dry place and pass through a good place. If this chemical substance encounters a tide, or is caused to change, it will cause adverse reactions. And it can avoid decomposition or other chemical reactions due to high temperature. If it is stored in a hot place, it may be dangerous and endanger the safety of the product.
Second, the isolation of other substances should not be ignored. 2-% -5-cyanotrifluoroacetyl aniline has specific properties and is easy to cause reactions to some substances. Acid, oil and gas, all of them are damaged. In the event of accidental contact, or strong reaction, a large amount of energy is released, or even an explosion is caused, endangering life and safety.
Third, the process needs to be properly packaged. In a combined container, it can be kept confidential and leaked. The packaging materials used can withstand a certain amount of external force to prevent the container from being damaged during the process, resulting in chemical substances being released. And the tools also need to be kept dry and clear, and they are in line with the safety of hazardous chemicals.
Fourth, the prevention of the operator is essential. The handling of the storage or the operation in the process is essential, and everyone has to prevent it, such as protective clothing, gloves, eyes, etc. This is due to the damage caused by chemical substances or human skin, eyes, respiratory tract, etc. If it is not prevented, once it is exposed or inhaled, it will not be safe and endanger health.
Fifth, it is clear and clear. On the container where it is stored, there must be eye-catching and dangerous products. Identify the product name, characteristics, and emergency treatment methods. In this way, if an accident occurs, the person can quickly take corrective measures to reduce the harm.