2 Bromo 3 Chlorobenzotrifluoride
Fluoride

2-Bromo-3-Chlorobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

306869

Chemical Formula C7H3BrClF3
Molar Mass 261.45 g/mol
Appearance Liquid (usually)
Boiling Point Approx. 193 - 195 °C
Solubility In Water Insoluble (organic compound with non - polar groups)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low vapor pressure at room temperature (due to relatively high molar mass and non - volatile nature)
Chemical Formula C7H3BrClF3
Molecular Weight 260.45
Appearance Liquid (usually)
Boiling Point Approximately 198 - 200 °C
Density Around 1.7 - 1.8 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low at room temperature
Flash Point Approximately 83 °C
Stability Stable under normal conditions but may react with strong oxidizing agents
Packing & Storage
Packing 500g of 2 - Bromo - 3 - Chlorobenzotrifluoride packaged in a sealed glass bottle.
Storage 2 - Bromo - 3 - Chlorobenzotrifluoride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and bases to avoid potential chemical reactions.
Shipping 2 - Bromo - 3 - Chlorobenzotrifluoride is a chemical. Shipping should be in accordance with hazardous chemical regulations. It must be properly packaged in suitable containers, labeled clearly, and transported by carriers approved for such chemicals.
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2-Bromo-3-Chlorobenzotrifluoride
General Information
Historical Development
About the historical development of 2-bromo-3-chlorotrifluorotoluene
In the past, chemical sages explored the mystery of substances, and in the field of organic synthesis, they worked tirelessly. The compound 2-bromo-3-chlorotrifluorotoluene was initially hidden in the unknown.
Scholars worked hard to explore it with various techniques. At the beginning, the synthesis road was full of thorns, the reaction conditions were harsh, and the yield was quite low. However, everyone was determined to change over the years and improve the reaction method. From the selection of reagents to the precise regulation of conditions, progress has gradually been made.
In the past, synthesis was difficult, and only a small amount could be obtained, which was only for research purposes. After continuous refinement, the reaction efficiency was improved, and the yield was gradually higher, so it could be prepared on a large scale. Its application has also become wider and wider, emerging in the fields of medicine, materials, etc., and its contribution to the advancement of science and technology and the goodness of life has gradually become apparent. All this is due to the diligent research of chemists of all ages, which has caused 2-bromo-3-chlorotrifluorotoluene to rise from obscurity and shine in this world.
Product Overview
There is a substance named 2 - Bromo 3 - Chlorobenzotrifluoride. What is its appearance? This is an organic halide with a unique structure. On the benzene ring, bromine and chlorine atoms are arranged in an orderly manner, and trifluoromethyl is connected.
Looking at its physical properties, under room temperature, it may be a colorless to slightly yellow liquid with a special odor. Because it contains halogen atoms and trifluoromethyl, its boiling point, melting point and other properties are different from common hydrocarbons.
When it comes to chemistry, halogen atoms are active and can participate in many reactions. In the nucleophilic substitution reaction, bromine and chlorine atoms may be replaced by nucleophiles, and then various compounds are derived.
This substance is widely used in the field of organic synthesis. It can be used as a key intermediate for the preparation of medicines, pesticides and functional materials. By ingeniously designing reaction paths, complex and functional molecular structures can be constructed, which contributes to chemical research and industrial development.
Physical & Chemical Properties
2 - Bromo - 3 - Chlorobenzotrifluoride is an important chemical substance. Its physical and chemical properties are particularly critical. In terms of physical properties, this substance has its unique color, taste and appearance at room temperature or in a specific phase state. Its boiling point, melting point and other data are related to its state changes under different temperature conditions. The value of density is of great significance for measuring the relationship between its mass and volume.
From the perspective of chemical properties, the presence of bromine and chlorine atoms in this substance makes it have unique reactivity. Under specific chemical reaction conditions, these halogen atoms can participate in many reactions such as substitution and addition, showing the characteristics of interacting with other chemical substances. Its chemical stability cannot be ignored either. In different environmental media, it may exhibit different chemical behaviors, which is what chemical researchers need to explore in depth.
Technical Specifications & Labeling
Today there is a product called "2 - Bromo 3 - Chlorobenzotrifluoride". The technical specifications and identification (commodity parameters) of this product should be carefully studied by our generation.
This substance, looking at its chemical structure, has established atomic positions of bromine (Bromo) and chlorine (Chlor), and is connected to the benzene ring containing trifluoromethyl. Regarding its technical specifications, the purity must be extremely high, and the impurity content must be minimal before it can be used. Its physical properties, such as melting point, boiling point, density, etc., are fixed and need to be accurately measured and recorded.
As for the identification, the commodity parameters should be clear, and the types of elements contained, the number of atoms and the connection method should be described in detail. In this way, the user can see at a glance, and there is no risk of misuse when researching and applying, so as to ensure the accuracy of the experiment and the smooth production.
Preparation Method
The method of preparing 2 - Bromo - 3 - Chlorobenzotrifluoride is related to the raw materials and production process, reaction steps and catalytic mechanism. First, take appropriate raw materials, such as compounds containing fluorine, chlorine and bromine. In a specific order, put them into the reactor in a reasonable ratio. First, set the appropriate reaction temperature and pressure so that the reactants can fully function. The reaction step is to make some raw materials start a substitution reaction, and promote its activity with a specific catalyst to accelerate the reaction process. After the substitution is appropriate, then adjust the conditions and perform addition or other reactions. In this process, the temperature, pressure and reaction time are precisely controlled, so that each step of the reaction can achieve the desired effect. In this way, after a series of operations, it is expected to obtain pure 2-Bromo-3-Chlorobenzotrifluoride, and the yield is considerable, which meets the production requirements.
Chemical Reactions & Modifications
Taste the wonders of chemistry, the changes are countless, related to the transformation of substances and the improvement of properties. In today's words 2 - Bromo - 3 - Chlorobenzotrifluoride this substance, its chemical reaction and modification are really the weight of our investigation.
To observe its reaction, or to use various reagents to adjust its conditions, such as temperature control, pressure change, rearrangement of molecules, and bond change. The position of halogen elements can be shifted due to reactions, and the structure can be changed to obtain new substances.
As for modification, it is designed to optimize its properties, or increase its stability, so that it can survive in different environments; or adjust its activity, which is convenient for subsequent synthesis needs. Or change its solubility, which is conducive to separation and purification.
In order to achieve this goal, it is necessary to investigate the reaction mechanism in detail, understand the micro-interaction between molecules, and apply it to this substance with precise methods to achieve an ideal state, which is used for chemical purposes.
Synonyms & Product Names
In the field of Wenfu Chemistry, 2 - Bromo - 3 - Chlorobenzotrifluoride this thing is quite important in the industry. Its synonymous name is well studied by scholars. Or "2 - Bromo - 3 - Chlorotrifluorotoluene", which is directly described as its chemical composition. Also known as "m-chloro-o-bromotrifluorotoluene", it is named after its position.
As for the business name, it is also different according to the needs of the city. The business name is to recognize its special, or to take the name of Easy to Remember, in order to promote. Although the name is different, it is actually the same thing. As far as researchers are concerned, no matter what the name is, they should be clear about its nature and use it in order to make good use of it and contribute to the progress of chemistry.
Safety & Operational Standards
2 - Bromo - 3 - Chlorobenzotrifluoride Safety and Operation Specifications
2 - Bromo - 3 - Chlorobenzotrifluoride, chemical products are also used. If you want to use this product, you must first know its safety and operation, before you can protect your health and health.
This product has a certain danger. Its pungent smell, if inhaled, can affect the respiratory tract, causing cough, respiratory distress and other diseases. Skin contact, or cause pain, pain, and sensitivity. Entering the eyes, it will harm the eyes and cause shadow force. Therefore, be extra careful when operating.
The operation of the product must be used. It is advisable to prevent clothing and wear gloves to separate the skin. It is also necessary to wear an eye mask to protect the eye. In the place of operation, the jellyfish must pass well, and it can be arranged in a row, so that the jellyfish can be quickly discharged, so as not to gather in the room.
Take the jellyfish, it is appropriate to use it, and do not let it out. If you accidentally wash the skin, quickly wash it with a lot of water, and then wash it with soap. If it enters the eyes, immediately wash it with water for more than 15 minutes, and then it will be ready. If inhaling, quickly pass the jellyfish, and keep breathing, it is necessary to ask for help.
The method of survival should not be ignored. It is appropriate to store it in the air, dry, and clear, which is the source of fire and smoke. Do not mix with oxidation, raw materials, etc., to prevent biochemical reactions and cause damage.
Therefore, Operation 2 - Bromo - 3 - Chlorobenzotrifluoride, keep the operation safe, and do not slack off. In this way, you can ensure your own safety and make the research work profitable.
Application Area
2-Bromo-3-Chlorobenzotrifluoride, organic compounds are also. Its application field is quite wide, and it can be used as a key intermediate in the field of medicinal chemistry. With this material, many drug molecules with specific biological activities can be synthesized to help the treatment of diseases.
In materials science, it also has important uses. Using it as a raw material, it can prepare polymer materials with special properties, or be used to improve the stability and weather resistance of materials, so that the materials are suitable for more harsh environments.
And in the fine chemical industry, 2-Bromo-3-Chlorobenzotrifluoride can participate in the synthesis of a variety of fine chemicals, giving unique properties to related products, expanding their application range, and promoting the innovative development of the chemical industry.
Research & Development
I have been researching this thing in "2 - Bromo - 3 - Chlorobenzotrifluoride" for several years, and I have gained a lot of experience. At the beginning, I explored its synthesis method, painstakingly searched for a path, and tried many times and failed, but I am not discouraged.
After repeatedly studying ancient books and studying the experience of predecessors, I finally got something. Improve the synthesis process to increase the yield. And observe its physical and chemical properties in detail, and clarify its characteristics.
Looking at this thing today, it has potential in the fields of medicine and materials. I will continue to refine my research and expand its application, hoping to contribute to the industry, so that this achievement can be widely used for the benefit of everyone, so as to achieve the grand ambition of research and development.
Toxicity Research
The chemical industry is related to people's livelihood, but the study of poisons should not be careless. Today there are 2 - Bromo - 3 - Chlorobenzotrifluoride this substance, and the study of its toxicity is very important.
When studying the toxicity of this substance, it is necessary to observe its impact on living beings. Or touch the skin to see if there are any abnormalities, redness, swelling and ulceration; or enter the breath to see the change of its breath, the sign of asthma and suffocation. It is also necessary to study its metabolism in the body, where it accumulates, and what organs are injured.
The test of toxicity should be rigorous and scientific. Do not take it lightly, in order to prevent omission, the spread of poison and disease, and endanger people's lives. Only by studying in detail and understanding its toxicity, can we make good policies, protect the safety of the living, protect the environment, and make the chemical industry prosperous but harmless, and profitable for a long time.
Future Prospects
Prospects for the future, especially for things that have been transformed. Today there are 2 - Bromo - 3 - Chlorobenzotrifluoride this thing, its undeveloped development, and its full potential.
This compound has unique properties and uses. In the field of development, it may be the cornerstone of new research, helping to eliminate diseases and relieve the suffering of the people. In the field of materials, it may also be able to give birth to new materials, which are solid and durable, to meet the needs of each country.
Furthermore, if the method of synthesis can keep improving, and the rate of improvement will increase day by day, the cost will decrease. Costs fall and volume rises, which will definitely promote the prosperity of each other.
In the future, if the researchers can continue to explore, dig deep into its characteristics, and make good use of its capabilities, 2 - Bromo - 3 - Chlorobenzotrifluoride will be able to expand the color, in many fields such as materials, materials, etc., and create a new situation. This is the expectation of our researchers.
Historical Development
In the past, Youji devoted himself to the study of the compound 2-Bromo-3-Chlorobenzotrifluoride. At the beginning, his understanding was quite shallow, and he only knew a little about its fur. However, the heart of a scholar is as firm as a rock, and he will not stop exploring.
The years pass, and the research deepens. In the early days, limited to utensils and knowledge, progress was slow. However, everyone was not discouraged, thinking hard, and experimenting repeatedly. Gradually gaining something, understanding its nature one or two.
In the Middle Ages, the technology advanced a little, and the reaction mechanism began to have a deeper investigation. Although there is still a lot of fog, the dawn has already appeared. The public studied day and night, and read the literature, hoping to make a breakthrough.
In recent times, science and technology have taken off, and the research in 2-Bromo-3-Chlorobenzotrifluoride has also made great progress. The structure is clear and the application is wider. The problems of the past are more resolved today. The historical evolution of this compound depends on the diligence of researchers in all dynasties. Only then can it have today's grand scene and be used by future generations for great benefit.
Product Overview
Today there is a substance called "2 - Bromo - 3 - Chlorobenzotrifluoride". This is a chemical substance, composed of bromine (Bromo), chlorine (Chloro) and trifluoromethyl (benzotrifluoride). Its shape and color, at room temperature or as a liquid, clear and colorless, with a special smell. Its properties, due to the presence of halogen atoms, are quite chemically active. The presence of bromine atoms and chlorine atoms makes this substance very useful in the field of organic synthesis. It can be used as a reaction intermediate, participating in nucleophilic substitution, electrophilic addition and other reactions, assisting in the construction of organic molecular structures. In the chemical industry, or used to create new materials, medicines, pesticides and other substances. After a delicate synthesis process, this pure substance can be obtained. However, when operating, one must be cautious, as it is toxic and corrosive to a certain extent, which is related to safety and cannot be ignored.
Physical & Chemical Properties
There is a substance named 2 - Bromo 3 - Chlorobenzotrifluoride. Its substance has physical and chemical properties. Looking at its shape, it may be a colorless liquid at room temperature, and it has a specific taste. Its boiling has a fixed number. Due to the intermolecular force, the boiling point is in a certain range, so that it can rotate gas and liquid at a specific temperature.
On its solubility, it is quite soluble in organic solvents. Due to the principle of similar miscibility, its molecular structure is compatible with organic solvents. It is also chemically active. The halogen atom on the benzene ring is easy to cause the change of nucleophilic substitution. Because the halogen atom absorbs electrons, the electron cloud density of the benzene ring changes, and it is reactive. This characteristic makes it widely used in the field of organic synthesis, and can be used as a raw material to produce a variety of fine chemicals. It is also essential for chemical research and industrial production.
Technical Specifications & Labeling
Today there is a product, name 2 - Bromo 3 - Chlorobenzotrifluoride. In terms of technical specifications and labels (product parameters) of this product, our generation should study it in detail.
The properties of this substance need to be clear about its color, state, taste, etc. Its physical and chemical properties, such as melting point, boiling point, solubility and other parameters, must be accurately determined and marked. As for purity, it should be strictly controlled, and the types and proportions of impurities it contains should be specified.
On the label, in addition to the name, the chemical formula and molecular weight should also be clearly marked. Safety labels are indispensable to warn its possible dangers, such as toxicity, corrosiveness, etc., so that users can handle it with caution. The technical specification should detail its preparation process and quality control standards to ensure the stability and consistency of the product, so that the substance can meet the needs of all applications without error.
Preparation Method
To prepare 2-bromo-3-chlorotrifluorotoluene, the method is as follows:
Select the raw material, and prepare suitable halides and fluorine-containing reagents. The former should be reactive, and the latter should be pure.
Synthetic process, first halogenate the substrate with a specific halogenating agent, and control the temperature in a moderate range to make the reaction smooth. Then introduce fluorine-containing groups. This step requires precise adjustment of reaction conditions, such as pressure, duration, etc.
Reaction step, the first step is halogenation, and the substrate and halogenating agent are added to the reaction kettle, stirred evenly, and slowly heated until the reaction starts. When the reaction progress reaches the standard, the temperature is lowered. Second-step fluorination, adding fluorine-containing reagents, strictly controlling temperature and pressure, timely monitoring, until the reaction is complete.
Catalytic mechanism, high-efficiency catalysts are selected to lower the reaction energy barrier and accelerate the reaction process. The amount of catalyst is moderate, too much or side reactions. And the catalyst needs to be highly selective to ensure the purity of the product. In this way, 2-bromo-3-chlorotrifluorotoluene can be prepared according to this, and the ideal product can be obtained.
Chemical Reactions & Modifications
2 - Bromo - 3 - Chlorobenzotrifluoride is an important compound in organic synthesis. Its chemical reaction and modification are related to the synthesis efficiency and product characteristics.
In the past, the reaction of preparing this compound may have low yield and poor selectivity. Chemists have worked hard to explore the improvement method. After repeated experiments and research, efforts have been made to change the reaction conditions.
Adjusting the reaction temperature and pressure, it was found that moderate heating and precise pressure control can promote the reaction rate and increase the selectivity of the product. At the same time, the suitable catalyst was screened and the application of the new catalyst greatly optimized the reaction process, resulting in a significant increase in the yield.
The proportion of the reactants is carefully considered, and the optimum ratio is obtained after precise preparation, so that the reaction can be efficiently carried out in the direction of generating the target product, so as to achieve the optimization of the chemical reaction and modification of this compound, and lay a solid foundation for its wide application in chemical industry and other fields.
Synonyms & Product Names
Today there is a thing called "2 - Bromo - 3 - Chlorobenzotrifluoride". This chemical thing, in the industry, is also known as the complex.
The field of Guanfu chemistry also refers to this product, and the titles are different. Or according to its characteristics, structure, or from habit and convenience, various names of synonyms arise. Among businesses, the names of their products also vary according to the needs of the city and the rules of the industry.
In the names of synonyms, although the words are different, they all refer to this "2 - Bromo - 3 - Chlorobenzotrifluoride". The existence of various names is to facilitate communication and application by all parties. Those who study this product should know its various names in order to achieve accuracy, and there is no risk of hindrance in research and practice. In this way, it will not only live up to the rigor of chemical inquiry, but also facilitate the smooth use of this product in various fields.
Safety & Operational Standards
About the safety and operation of 2-bromo-3-chlorotrifluorotoluene
Fu 2-bromo-3-chlorotrifluorotoluene is a common chemical in chemical research. Its properties are special, related to safety and operation standards, and should not be careless.
In terms of safety, this product may be dangerous. Its odor is pungent, if inadvertently inhaled, it can cause respiratory discomfort and even damage the lungs. Therefore, when operating, it is necessary to ensure good ventilation, and it is advisable to have ventilation equipment, such as a fume hood, so that the gas can be discharged in time to protect the human body from its harm. Furthermore, this chemical comes into contact with the skin, or causes allergies, burns and other diseases. It is necessary to wear protective gloves in front of protective clothing and protective gloves during operation to prevent it from dating the skin. If it is unfortunate to come into contact, rinse with plenty of water as soon as possible and seek medical treatment.
As for the operation specifications, the first weight is accurately weighed. Due to the strict requirements of the dosage due to chemical reactions, there is a slight deviation, or the reaction results are very different. When weighing, precise instruments must be used, and the operation is cautious to avoid the risk of leakage. Secondly, the control of the reaction conditions is crucial. Factors such as temperature, pressure, and reaction time can all affect the reaction process and product purity. Therefore, it must be carefully adjusted according to the established reaction plan, and must not be arbitrarily made and changed at will. During the reaction process, it is also necessary to closely observe the phenomenon. If there is any abnormality, stop it immediately to check the cause and prevent accidents.
Furthermore, storage is also exquisite. 2-Bromo-3-chlorotrifluorotoluene should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. Due to its active chemical properties, it is feared that there will be a violent reaction in case of fire or oxidants, endangering safety.
In short, in the research and use of 2-bromo-3-chlorotrifluorotoluene, safety should be the priority, and operating norms should be followed to ensure the smooth operation of the experiment and the safety of personnel.
Application Area
Today, there is a thing called "2 - Bromo - 3 - Chlorobenzotrifluoride", which can be used in many fields. In the process of pharmaceutical research and development, it may be able to help synthesize special drugs and contribute to the elimination of diseases. In the field of material research and development, it can be used as a unique raw material to create new materials with outstanding performance, which are used in many key places such as electronics and aviation. In the field of fine chemicals, it may be a key ingredient in delicate formulations to produce high-quality fine chemicals and serve people's livelihood. Although it is not widely known, it has extraordinary potential. With time and careful study, it will be able to shine in various application fields and benefit the world.
Research & Development
The industry of chemical industry is changing with each passing day, and new products are emerging one after another. Today there are 2 - Bromo - 3 - Chlorobenzotrifluoride this product, which is the key to academic research.

The best people think hard about the method of its preparation. Or explore the conditions of the reaction, the change of temperature and humidity, and the catalysis, all of which are considered in detail. Strive for an efficient and pure way to increase its yield and improve its quality.
In the field of application, it is also developed in many ways. Thinking about it in the fields of medicine and materials, it can be used for a lot. Or it is the foundation of good medicine to heal diseases; or it is the source of new materials to increase the energy of utensils.
We should carry on the ambitions of our predecessors and study tirelessly. Looking forward to the future, this product will shine in various fields, contributing to the advancement of science and technology and the benefit of people's livelihood, so as to achieve a higher level.
Toxicity Research
Today, there is a product called 2 - Bromo 3 - Chlorobenzotrifluoride. In the field of our chemical research, the study of its toxicity is quite important.
This product belongs to the genus of halogenated aromatics, and the halogen atom is sexually active or toxic. To clarify its toxicity, various methods should be used. First, animal experiments can be carried out to observe its impact on the physiological function and behavior of living beings. If rodents are affected by it, observe the changes and growth of their organs. Second, study its response at the biochemical level to explore its interaction with biological macromolecules, such as proteins and nucleic acids, and investigate whether it interferes with normal metabolism.
After various inquiries, I hope to know the details of the toxicity of 2 - Bromo 3 - Chlorobenzotrifluoride, for its production and use, and for the protection of people and the environment, to provide a solid evidence to prevent its harm from not being born, and to protect the world's well-being.
Future Prospects
The future outlook of the husband is the key to 2 - Bromo - 3 - Chlorobenzotrifluoride this thing. Looking at this chemical thing today, it has unique properties and may have extraordinary uses in various fields.
We imagine that in the future, it may emerge in the development of medicine. With its characteristics, it may help to create new medicines and solve the pain of everyone. And in the field of materials science, it is also expected to become the foundation of new materials, endowing materials with special properties, such as better corrosion resistance and wear resistance, so that materials can be durable in various environments.
Furthermore, in the process of chemical synthesis, 2 - Bromo - 3 Chlorobenzotrifluoride or as an important raw material, leading the new transformation of the synthesis path, promoting more efficient and environmentally friendly synthesis methods, and contributing to the sustainable development of the chemical industry. All of these are our prospects for its future development, and we hope it will shine in the future.
Frequently Asked Questions
What are the chemical properties of 2-Bromo-3-Chlorobenzotrifluoride?
2-Bromo-3-chlorotrifluorotoluene is an organic compound with unique chemical properties. It is colorless to light yellow liquid and is very important in the field of organic synthesis.
In terms of chemical activity, both bromine and chlorine atoms in this compound are halogen atoms, which are highly active and can participate in many nucleophilic substitution reactions. For example, when encountering nucleophilic reagents, halogen atoms can be replaced by nucleophilic groups to form new organic compounds. This property makes it a key intermediate for the preparation of complex organic molecules.
From the perspective of stability, trifluoromethyl in the molecule has strong electron absorption, which can affect the distribution of molecular electron clouds, which in turn has an effect on the stability and reactivity of compounds. The presence of trifluoromethyl makes the compound more stable under specific conditions, and also changes its reaction check point and reaction rate.
In terms of solubility, due to the halogen atom and trifluoromethyl, this compound has good solubility in organic solvents such as dichloromethane, chloroform, and ether, but poor solubility in water. This solubility characteristic is of great significance in the reaction operation and product separation process of organic synthesis, which facilitates the choice of reaction conditions and subsequent treatment.
In chemical reactions, 2-bromo-3-chlorotrifluorotoluene can undergo a variety of reactions. In addition to nucleophilic substitution reactions, it can also participate in metal-catalyzed coupling reactions, such as palladium-catalyzed cross-coupling reactions, to construct carbon-carbon bonds, expand molecular structures, and synthesize organic compounds with different functional groups and structures.
In summary, 2-bromo-3-chlorotrifluorotoluene plays a key role in the field of organic synthesis chemistry due to its reactivity of halogen atoms, electronic effects and specific solubility of trifluoromethyl, providing an effective way for the preparation of many organic compounds.
What are the physical properties of 2-Bromo-3-Chlorobenzotrifluoride?
2-Bromo-3-chlorotrifluorotoluene is one of the organic compounds. It has unique physical properties, let me tell you in detail.
First of all, its appearance, at room temperature, is mostly colorless to light yellow transparent liquid, and it looks clear, like jade nectar. Its smell is specific, although it is not as stinky and pungent, it also has a clear organic smell, and it can be known by smelling that it is unusual.
When it comes to boiling point, it is about a certain temperature range. This temperature value varies slightly due to slight changes in external conditions, but is roughly within a certain range. The boiling point is the critical temperature at which a substance changes from liquid to gas, which is related to its phase change in different environments.
Melting point is also an important physical property. The value of the melting point is established, and it can be known that this compound will gradually condense from liquid to solid at a specific low temperature. This property is of great significance for the storage and transportation of substances.
Furthermore, its density is also fixed. The density is also the mass of the substance contained in the unit volume. The density of 2-bromo-3-chlorotrifluorotoluene makes it follow specific physical laws when mixed or separated from other substances.
In terms of solubility, it has a certain solubility in many organic solvents. It is soluble in some organic solvents, such as common organic solvents, but its solubility in water is very small. This difference in solubility is due to the difference in the interaction between its molecular structure and water molecules and organic solvent molecules.
Volatility, it is volatile to a certain extent. Although it is not very volatile, such as some light hydrocarbons, it will slowly evaporate into the air under appropriate temperatures and environments. This characteristic should be taken into account during use and storage to prevent it from dissipating or causing safety issues.
In summary, the physical properties of 2-bromo-3-chlorotrifluorotoluene, such as appearance, odor, boiling point, melting point, density, solubility, and volatility, play a key role in its application in chemical engineering, scientific research, and many other fields. It is also necessary for relevant practitioners to be familiar with it.
What are the main uses of 2-Bromo-3-Chlorobenzotrifluoride?
2-Bromo-3-chlorotrifluorotoluene, this substance has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Due to its special structure, it contains halogen atoms and trifluoromethyl, giving it unique chemical activity and can participate in a variety of organic reactions, helping to build complex organic molecular structures.
In the direction of pharmaceutical research and development, drug molecules can be introduced through a series of reactions, and trifluoromethyl can be used to optimize drug properties by strong electron absorption and special spatial effects, such as enhancing fat solubility, enhancing biological activity, and improving metabolic stability, laying the foundation for the creation of new and efficient drugs.
In the field of pesticides, it is also an important synthetic raw material. With the help of halogen atoms and trifluoromethyl on the physiological activities of pests, it is synthesized and converted into a pesticide with specific insecticidal, bactericidal or herbicidal properties. With its unique chemical properties, it can achieve high biological efficiency on the target, while reducing the impact on the environment and non-target organisms.
In addition, in the field of materials science, participate in the synthesis of functional materials. Its special structure can endow materials with excellent properties such as chemical corrosion resistance, high temperature resistance, low surface energy, etc., used in the preparation of special coatings, engineering plastics, electronic materials, etc., to meet the needs of special performance materials in various fields. In short, 2-bromo-3-chlorotrifluorotoluene is of great significance in many fields of chemical industry and plays a key role in promoting the development of
What is the preparation method of 2-Bromo-3-Chlorobenzotrifluoride?
The method for preparing 2-bromo-3-chlorotrifluorotoluene can be carried out as follows.
First take an appropriate starting material and use trifluorotoluene as the base. Because of the presence of trifluoromethyl on the benzene ring in its structure, it is conducive to the positioning of subsequent reactions.
In an appropriate reaction vessel, add an appropriate amount of reaction solvent, such as halogenated hydrocarbon solvents, such as dichloromethane, etc. This solvent has good solubility to the reactants and reaction intermediates, and its properties are relatively stable and do not interfere with the main reaction.
Then, the reaction system is cooled to a specific low temperature, generally -10 ° C to 0 ° C is appropriate. Slowly drop brominating reagents, such as a mixture of bromine (Br ²) and an appropriate catalyst, which can be selected from iron powder or iron tribromide, etc. The brominating reagent selectively undergoes electrophilic substitution with the trifluorotoluene benzene ring at low temperature and under the action of the catalyst. Because trifluoromethyl is the meta-locator, bromine atoms preferentially replace the hydrogen atoms of the trifluoromethyl meta-site on the benzene ring to form the intermediate product 3-bromotrifluorotoluene.
Next, the reaction system is warmed to a moderate temperature, such as 30 ° C - 50 ° C, and a chlorinated reagent such as chlorine (Cl2) or N-chlorosuccinimide (NCS) is added. The chlorination reagent and 3-bromotrifluorotoluene continue to undergo electrophilic substitution reaction. Under suitable conditions, the chlorine atom replaces the hydrogen atom of the bromine atom ortho-position on the benzene ring. After multi-step reaction operation, separation and purification steps, such as distillation, column chromatography, etc., the pure 2-bromo-3-chlorotrifluorotoluene can finally be obtained.
The whole preparation process needs to precisely control the reaction temperature, reagent dosage and reaction time to ensure the smooth progress of the reaction and improve the yield and purity of the target product.
2-Bromo-3-Chlorobenzotrifluoride what are the precautions in storage and transportation?
2-Bromo-3-chlorotrifluorotoluene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First words storage. This compound should be placed in a cool, dry and well-ventilated place. Cover because of its nature or affected by temperature and humidity, if it is placed in a high temperature and humid place, it may deteriorate. Keep away from fires and heat sources. Open flames and hot topics can easily cause combustion or explosion, endangering safety. It should be stored separately from oxidizing agents and alkalis, etc., and must not be mixed with them. If it reacts violently with their substances or causes danger. The storage area should be equipped with suitable materials to contain leaks, so as to prevent accidental leakage and timely treatment, so as not to cause greater harm due to its spread.
Subsequent transportation. Before transportation, make sure that the container is well sealed to prevent leakage. During transportation, the vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. When driving, be stable, avoid bumps and shocks, and prevent material leakage due to damage to the container. Drivers and escorts must be familiar with the characteristics, hazards and emergency treatment methods of this compound. During transportation, they should not stop at will, and stay away from populated areas and fire sources and other dangerous areas. In case of leakage and other emergencies, corresponding measures should be taken immediately to evacuate the crowd, seal the scene, and report to the relevant departments in a timely manner.