2 Amino 5 Fluorobenzotrifluoride
Fluoride
2-Amino-5-fluorobenzotrifluoride
Chemical Formula C7H5F4N
Molecular Weight 181.12
Appearance Colorless to light yellow liquid
Boiling Point 196 - 198 °C
Melting Point N/A
Density 1.379 g/cm³
Flash Point 81 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Purity Typically high - purity grades available, e.g., 98%+
FAQ

What are the main uses of 2-Amino-5-fluorobenzotrifluoride?

2-Amino-5-fluorotrifluorotoluene is also an organic compound. It has a wide range of uses and has important applications in many fields such as medicine, pesticides, and materials.

In the field of medicine, this compound is often a key intermediate for the synthesis of new drugs. Because it contains fluorine atoms, it can significantly change the physical and chemical properties of drug molecules, such as lipophilicity and stability, thereby improving the biological activity and pharmacokinetic properties of drugs. The development and synthesis of many antibacterial, anti-tumor, and neurological diseases drugs rely on it as the basic raw material, and it is converted into active pharmaceutical ingredients with complex structures through chemical reactions.

In the field of pesticides, 2-amino-5-fluorotrifluorotoluene is also an important synthetic raw material. After chemical modification and reaction, high-efficiency, low-toxicity and environmentally friendly pesticide products can be prepared. Due to its special structure, the prepared pesticide has high selectivity and activity to target organisms, and can effectively control pests, weeds and diseases, and ensure the yield and quality of crops.

In the field of materials, this compound can be used to prepare functional materials. For example, in the synthesis of organic optoelectronic materials, its structure can endow the materials with unique optical and electrical properties, which can be used in the manufacture of organic Light Emitting Diode (OLED), solar cells and other devices to improve their performance and efficiency.

In conclusion, 2-amino-5-fluorotrifluorotoluene plays a key role in many fields of modern chemical industry due to its special chemical structure, and has made great contributions to the development of medicine, pesticides and materials science.

What are the physical properties of 2-Amino-5-fluorobenzotrifluoride?

2-Amino-5-fluorotrifluorotoluene is a kind of organic compound. Its physical properties are particularly important, and it is related to its performance in various chemical processes and industrial applications.

First of all, its properties, under normal temperature and pressure, are mostly colorless to light yellow liquid, which is clear to see. The characteristics of this color state can be used as a preliminary basis for discrimination in actual operation and identification.

The melting point is between -10 ° C and 0 ° C. The melting point is also the critical temperature at which the substance changes from solid to liquid. In this temperature range, the arrangement and force between molecules of the compound change from solid to liquid. < Br >
In terms of boiling point, it is about 200 ° C to 210 ° C. The boiling point is the temperature at which the saturated vapor pressure of a liquid is equal to the external pressure. At this temperature, the compound converts from liquid to gaseous state. Higher boiling points indicate strong intermolecular forces, and more energy is required to vaporize it.

Density is also an important physical property, about 1.4 g/cm ³. Density reflects the mass of a substance in a unit volume, and this value is indispensable in operations such as material measurement and mixing.

Furthermore, its solubility is also worth exploring. In organic solvents such as dichloromethane and chloroform, 2-amino-5-fluorotrifluorotoluene has good solubility and can be miscible with it. However, in water, the solubility is very small. The difference in solubility is due to the difference between the polarity of the compound molecule and the polarity of the water molecule, and the difference in the strength of the force between the organic solvent molecules.

In addition, the compound has a certain volatility. Although it is not very volatile, it will still partially vaporize and escape when the exposure environment and temperature are slightly higher. And because it contains fluorine atoms and trifluoromethyl groups, its chemical properties are also unique, which affect the performance of its physical properties, such as melting point, boiling point, solubility, etc.

What are 2-Amino-5-fluorobenzotrifluoride synthesis methods?

There are many different ways to synthesize 2-amino-5-fluorotrifluorotoluene. The most common one is to use 5-fluoro-2-nitrotrifluorotoluene as the starting material and obtain it through reduction reaction. Among them, the reduction system composed of iron powder or zinc powder and hydrochloric acid is quite commonly used. 5-fluoro-2-nitrotrifluorotoluene is placed in a solution containing hydrochloric acid, slowly added iron powder or zinc powder, heated and stirred. This process is like the universe in a kettle, and the raw material is gradually converted under specific conditions. Nitro is reduced to form an amino group, and finally 2-amino-5-fluorotrifluorotoluene is obtained.

In addition, catalytic hydrogenation can also be used. Using 5-fluoro-2-nitrotrifluorotoluene as the base, palladium carbon or platinum carbon as the catalyst, in a hydrogen atmosphere, the reaction is under suitable temperature and pressure conditions. Hydrogen is like a smart messenger. Under the guidance of the catalyst, it interacts with the nitro group and gradually reduces it to an amino group to achieve the target product.

In addition, 2-chloro-5-fluorotrifluorotoluene is used as the starting material, and it is first reacted with ammonia. This reaction needs to be carried out under high pressure and in the presence of a specific catalyst. The chlorine atom is replaced by an amino group to obtain 2-amino-5-fluorotrifluorotoluene. Each method has its own advantages and disadvantages, depending on the actual demand, raw material availability and cost and many other factors.

What are the precautions in storage and transportation of 2-Amino-5-fluorobenzotrifluoride?

2-Amino-5-fluorotrifluorotoluene is an organic compound. During storage and transportation, the following matters should be paid attention to:

First, the storage place must be dry and well ventilated. This substance is prone to deterioration due to moisture, and poor ventilation will cause volatile gas to accumulate and cause safety hazards. Remember in the past, there was a workshop that was wet due to storage, which caused the properties of the compound to change, affecting subsequent use and adding a lot of trouble and loss.

Second, keep away from fire and heat sources. Because of its flammability, it can cause combustion and explosion in case of open flames, hot topics or. In the past, there were transportation vehicles that did not pay attention to stay away from heat sources, causing the temperature inside the car to rise, and the compound was dangerous. Fortunately, it was disposed of in time, and it did not cause a disaster.

Third, it needs to be stored separately from oxidants and acids. Because of its active chemical nature, contact with these substances, or react violently, causing danger. There were warehouses in ancient times, because they were not isolated from oxidants, a reaction occurred, and the fire spread, causing heavy losses.

Fourth, the storage container must be tightly sealed. To prevent volatile leakage, pollute the environment, and the volatile gas may be toxic, endangering human health. In the past, there have been leaks, causing pollution of the surrounding air and discomfort of personnel.

Fifth, when transporting, make sure that the container is fixed and stable, and prevent collision and dumping. There have been times when the vehicle was bumpy, the container was dumped, and the compound leaked during transportation, which affected the transportation process and polluted the surrounding area.

Sixth, transportation and storage personnel, when professionally trained, are familiar with its characteristics and safe operation methods. Without professional knowledge, it is difficult to deal with emergencies in a timely and correct manner. There have been novices who have not been trained to work, and they do not know how to deal with leaks, resulting in the expansion of the harm.

All of these are important points that should not be ignored when storing and transporting 2-amino-5-fluorotrifluorotoluene. They need to be handled with caution, so that the security is safe.

What is the market outlook for 2-Amino-5-fluorobenzotrifluoride?

2-Amino-5-fluorotrifluorotoluene is a valuable chemical raw material in the field of organic synthesis, which is widely used in many industries such as medicine, pesticides, materials, etc. Its market prospect, looking at the current situation, can be said to have great potential and opportunities and challenges coexist.

In the pharmaceutical industry, with the continuous increase in investment in the research and development of innovative drugs, the synthesis of many new drugs requires intermediates with specific structures. 2-Amino-5-fluorotrifluorotoluene can be used as a key intermediate for the synthesis of a variety of compounds with special pharmacological activities due to its unique chemical structure. For example, in the development of some anti-cancer drugs and antiviral drugs, this compound plays an indispensable role. With the aging of the global population and the increasing emphasis on health, the demand for various innovative drugs in the pharmaceutical market is increasing, which in turn brings a broad market space for 2-amino-5-fluorotrifluorotoluene.

In the field of pesticides, people's demand for high-efficiency, low-toxicity and environmentally friendly pesticides continues to rise. 2-amino-5-fluorotrifluorotoluene can be used to prepare pesticides with novel mechanisms of action to deal with increasingly complex pests and diseases. Modern agriculture pursues sustainable development and attaches great importance to the research and development and production of new pesticides, which undoubtedly provides a good opportunity for the expansion of 2-amino-5-fluorotrifluorotoluene in the pesticide market.

In the materials industry, with the advancement of science and technology, the demand for high-performance materials continues to grow. 2-Amino-5-fluorotrifluorotoluene can participate in the synthesis of polymer materials with special properties, such as high temperature and chemical corrosion resistant materials, and has broad application prospects in high-end fields such as electronics and aerospace.

However, its market development also faces many challenges. On the one hand, the synthesis process of 2-amino-5-fluorotrifluorotoluene is relatively complex and the production cost is high, which limits its large-scale application to a certain extent. To expand market share, more efficient and economical synthesis processes need to be developed. On the other hand, the environmental protection requirements of the chemical industry are becoming increasingly stringent, and the production process needs to meet strict environmental protection standards, which will undoubtedly increase operating costs and technical difficulties for production enterprises.

Despite the challenges, considering the development trends of various industries, 2-amino-5-fluorotoluene is expected to continue to grow in demand in the fields of medicine, pesticides, and materials due to its unique structure and properties. In the long run, the market prospect is quite promising.