2 Amino 5 Chlorobenzotrifluoride
Fluoride

2-Amino-5-Chlorobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

162945

Chemical Formula C7H5ClF3N
Molar Mass 195.57 g/mol
Appearance colorless to light yellow liquid
Boiling Point 215 - 217 °C
Melting Point N/A
Density 1.36 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point 93 °C
Pka N/A
Refractive Index 1.485 - 1.487
Chemical Formula C7H5ClF3N
Molecular Weight 195.57
Appearance Colorless to light yellow liquid
Boiling Point Around 210 - 212 °C
Density 1.384 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point Around 90 °C
Vapor Pressure Low at room temperature
Stability Stable under normal conditions
Packing & Storage
Packing 250g of 2 - Amino - 5 - Chlorobenzotrifluoride packaged in a sealed, chemical - resistant bottle.
Storage 2 - Amino - 5 - Chlorobenzotrifluoride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and evaporation. It is advisable to store it in a dedicated chemical storage facility, separated from incompatible substances, to ensure safety.
Shipping 2 - Amino - 5 - Chlorobenzotrifluoride is shipped in accordance with chemical transport regulations. It's typically packaged in air - tight, corrosion - resistant containers to prevent leakage during transit, ensuring safe delivery.
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2-Amino-5-Chlorobenzotrifluoride
General Information
Historical Development
At the beginning of the 20th century, chemical research gradually flourished, and the compound "2 - Amino - 5 - Chlorobenzotrifluoride" began to enter the field of vision of researchers. At that time, chemical analysis methods began, and it was difficult to explore its structure and properties. However, scholars were not discouraged, and after repeated experiments, some of its characteristics were gradually clarified.
In the mid-term, chemical technology advanced, and the method of synthesizing this compound was gradually improved, and the purity was also improved. However, due to equipment and concepts, large-scale production was still hindered.
In the later stage, science and technology took off, analytical instruments were precise, and synthesis processes were refined. The production scale of "2-Amino-5-Chlorobenzotrifluoride" increased greatly, and it was gradually applied in medicine, materials and other fields. Its development path depends on the unremitting research of researchers of successive generations to achieve today's results.
Product Overview
Today there is a product called 2-amino-5-chlorotrifluorotoluene. This is a key raw material for organic synthesis and is widely used in the fields of medicine and pesticides. Its shape is colorless to pale yellow liquid with a special odor.
From the perspective of chemical structure, on the benzene ring, chlorine atoms, amino groups and trifluoromethyl groups are cleverly arranged, giving it unique chemical properties. The amino group has good activity and can participate in a variety of nucleophilic substitution reactions; the chlorine atom changes the electron cloud density of the benzene ring, which affects the reactivity; the strong electron absorption of trifluoromethyl enhances molecular stability and fat solubility.
Preparation of this product, often with specific aromatic hydrocarbons as the starting material, through a series of reactions such as halogenation and amination. However, the preparation process requires precise control of reaction conditions, and temperature, pressure, and catalyst are all key elements.
2-Amino-5-chlorotrifluorotoluene is a cornerstone in the stage of organic synthesis, making outstanding contributions to the creation of various novel compounds and the promotion of pharmaceutical and pesticide technology innovation.
Physical & Chemical Properties
On August 10, 2023, Yu Yu studied 2 - Amino - 5 - Chlorobenzotrifluoride this substance in the room. What is its appearance? From the perspective of it, it is a colorless to slightly yellow liquid, with a specific smell. Its boiling point is quite high, about several degrees, which makes it require specific temperature conditions when separating and purifying.
Its solubility is also observed. It is soluble in common organic solvents, such as ethanol and ether, but insoluble in water. This property is related to the polarity of the molecule, and its molecular structure makes the polarity different, so the solubility is different.
Furthermore, its chemical activity is also key. Under specific reaction conditions, it can react with many reagents, such as nucleophilic substitution reaction, because of its specific functional group layout, so that the reaction can occur in an orderly manner. These are all important physical and chemical properties, and are of great significance in industrial preparation and scientific research applications.
Technical Specifications & Labeling
Today there is a product, the name is 2 - Amino - 5 - Chlorobenzotrifluoride. Its process specifications and identification (product parameters) are the key. The process of this product needs to follow a rigorous method. From the selection of raw materials, it must be pure and free of impurities, and meet specific regulations. When preparing, the heat and duration are fixed, and a slight difference will affect the quality.
In terms of its identification, the product parameters must be clear. Such as purity geometry and impurity content, all need to be accurately marked. In this way, the user can understand it without the risk of misuse. The process specifications and identification complement each other, and the advantages and disadvantages of this product must not be ignored. Make sure that the process is in line with the specifications and the identification is accurate to get a good product.
Preparation Method
In the process of making 2-amino-5-chlorotrifluorotoluene, the raw materials and the production process, reaction steps and catalytic mechanism are the key. The raw materials are often fluorine, chlorine and amino-related compounds. At the beginning of the production process, the raw materials are mixed in a specific ratio and put into the reactor. In the first step of the reaction, under a suitable temperature and pressure, the raw materials are substituted, and the chlorine atoms are delicately connected to the benzene ring to obtain the key intermediate product.
Then, the reaction conditions are adjusted to promote the amination reaction and the precise introduction of amino groups. The catalyst in this process is crucial, which can speed up the reaction rate and improve the purity of the product. The catalytic mechanism lies in the ingenious interaction between the catalyst and the reactants to reduce the activation energy of the The reaction steps are closely interlocked, and the reaction temperature, time, and proportion of reactants need to be precisely controlled, so that high-purity 2-amino-5-chlorotrifluorotoluene products can be obtained to meet the needs of many fields.
Chemical Reactions & Modifications
Today there is a product called 2-amino-5-chlorotrifluorotoluene. In the field of chemistry, its reaction and modification are particularly important to us.
The reaction of this compound is related to many chemical pathways. Past experiments have found that it often changes uniquely when it encounters various reagents under specific conditions. However, the initial reaction state may not be perfect. Its yield is not sufficient, and by-products also exist, which limits its application.
In order to change this state, we have studied it for a long time. The temperature of the reaction, the amount of reagents, and the things that are easy to catalyze are finally obtained. After optimization, the reaction yield gradually increases, and the by-products gradually decrease. This is the work of chemical modification, which improves the properties of 2-amino-5-chlorotrifluorotoluene, and has more potential for application in the fields of medicine and materials, which can contribute to the development of chemistry.
Synonyms & Product Names
In 2024, the chemical industry is increasingly exploring "2-Amino-5-chlorotrifluorotoluene" (2 Amino 5 Chlorobenzotrifluoride). In the field of organic synthesis, it has a wide range of uses and can be used as a raw material for many fine chemicals, such as medicine, pesticides, dyes and other industries.
Exploring its synonyms and trade names is like digging for secrets. "2-Amino-5-chlorotrifluorotoluene", or also known as "5-chloro-2-aminotrifluorotoluene", although the word order has changed slightly, it refers to the same. As for the trade name, different manufacturers have their own names. Factory A may be called "eufluoroamine chlorine" in recognition of its superior quality; Factory B may be called "refined chlorofluoroamine" to highlight its refining power.
Chemists are like treasure hunters, who study synonyms and trade names carefully, aiming to understand the various terms in the market. When purchasing and researching, it is accurate and correct to avoid confusion. And behind different names, or hidden production processes and quality characteristics, insight into them can be used in chemical research and industrial applications without hindrance, so that "2-amino-5-chlorotrifluorotoluene" can play a perfect role.
Safety & Operational Standards
"An Zhiruosu, the rules of practice - about 2 - Amino - 5 - Chlorobenzotrifluoride product safety and operating procedures"
Fu 2 - Amino - 5 - Chlorobenzotrifluoride, chemical products are also. It is used in the field of experiment and industry. However, this object has certain risks, so the safety and operation norms cannot be ignored.
First word safety. This object may be harmful to the human body, touch the skin, fear discomfort, or even damage. If it enters the eyes, it is particularly harmful. Rinse with water as soon as possible and seek medical treatment. The smell of smelling may also disturb the respiratory system, so in this environment, ventilation must be good. When storing, it should be in a cool and dry place, away from fire and heat sources to prevent accidents.
Secondary operating specifications. When handling this object, it is necessary to wear protective gear, such as gloves, goggles, protective clothing, etc., to prevent its damage. In the experimental operation room, the instrument must be clean and accurate to prevent errors. When weighing, according to the accurate method, there should be no difference of millimeter. During the reaction process, strictly observe the rules of temperature and time, and observe its changes.
In addition, the disposal of waste should not be ignored. It must be classified and disposed of according to environmental protection principles, and cannot be discarded at will to avoid polluting the environment.
In short, the safety and operation standards of 2-Amino-5-Chlorobenzotrifluoride should be used with caution. Take it easy and follow the rules to ensure that everything goes smoothly and is safe.
Application Area
Today there is a thing called "2-Amino-5-chlorotrifluorotoluene". It can be used in various fields.
In the field of medicine, it can be used as a raw material for pharmaceuticals to help physicians make good medicines for treating diseases and relieve people's suffering. Physicians may use its chemical properties to blend medicines to achieve the effect of treating diseases and strengthening the body.
In the field of pesticides, it may be the key to insect control and seedling protection. With its unique properties, it can be made into a pesticide to protect crops from insect invasion, resulting in abundant food and food for all people.
In the research and development of materials, it may also be the foundation for creating new materials. With its characteristics, it is compatible with other things and becomes a new material with outstanding performance. It is used in equipment and utensils to make it more durable and convenient for everyone's life.
"2-Amino-5-chlorotrifluorotoluene" has a wide application field and is of great significance to people's livelihood. It is a chemical substance that cannot be ignored.
Research & Development
Recently, in the research room, we focused on the compound 2 - Amino - 5 - Chlorobenzotrifluoride. This substance has unique properties and may have important application potential in many fields.
We studied its structure in detail to clarify its inherent characteristics. After repeated experiments, we observed its reaction law and hoped to find a way to optimize the synthesis. The road of synthesis is full of difficulties, but we will continue to study and strive to improve.
In the exploration, we refer to many previous studies, take the essence and remove the dross. We also communicate with colleagues to broaden our thinking.
I firmly believe that through continuous research and exploration, we will be able to gain a deeper understanding of 2-Amino-5-Chlorobenzotrifluoride, achieve technological breakthroughs, promote its application in industry, medicine and other fields, and contribute to the academic community and industry.
Toxicity Research
Taste, smell and study of poison, the importance of people's livelihood. Today there are 2 - Amino - 5 - Chlorobenzotrifluoride this substance, and the study of its toxicity should not be ignored.
Examine this substance in detail, and it is necessary to explore its nature and its source. Observe its chemical structure, or contain the cause of toxicity. Try to test it by various methods, observe its impact on living things, and observe its response to other things.
However, the study of toxicity is not achieved overnight. Be cautious and careful, experiment many times, and record its changes in detail. From micro-focus, from shallow to deep, can get its true meaning. In order to prevent and treat, protect the well-being of everyone, and maintain the tranquility of the environment, this is the important task of those who study toxicity.
Future Prospects
In today's 2 - Amino - 5 - Chlorobenzotrifluoride, this product has deep potential in the field of chemical industry. Future development can be exhibited in many ways.
First, the way of pharmaceutical research and development may be a key raw material to help the creation of new drugs, cure various diseases, and solve patients' diseases. Second, in the realm of material science, through ingenious synthesis, the unique properties of materials are given to high-tech products and lead the industry forward.
Although the current research is not complete, with time, we will be able to improve the synthesis process, reduce costs and yield, and achieve the ideal state. The future is bright, just like the stars are waiting to be picked. When our generation of scientific researchers diligently explore, they will surely open up a broad new situation, so that this thing will shine in the future and benefit the world.
Historical Development
In the chemical industry, there are many categories and new substances emerging in an endless stream. Today, there is 2-amino-5-chlorotrifluorotoluene, which was not well known to everyone in the past.
At the beginning, scholars explored the field of chemistry, focusing on various common substances, which were still hidden in the corner of research. Later, with the advance of research, chemical technology became more and more mature, and everyone's attention gradually focused on it.
Researchers observed its characteristics, explored its production method, and after several years, they came to understand its synthesis method. From the initial ignorance to the gradual realization, every step depends on the study of scholars. Or repeatedly failed in the experiment, but the determination was not changed, and finally obtained the wonderful recipe for synthesis. As a result, 2-amino-5-chlorotrifluorotoluene began to appear in the chemical industry stage, started its journey in industrial applications and other fields, and laid the foundation for many future research and production.
Product Overview
Today there is a chemical called 2-amino-5-chlorotrifluorotoluene, which is the chemical we have been working on. Its color is pure and good quality, and its shape is [specific physical state, can be supplemented such as powder, crystal, etc.]. This substance is used in the field of chemistry and has a wide range of uses.
Looking at its structure, it contains amino groups, chlorine atoms and trifluoromethyl groups. This unique structure gives it specificity. Because it contains trifluoromethyl groups, it has good chemical stability and hydrophobicity; the existence of amino groups makes it participate in a variety of chemical reactions, such as nucleophilic substitution, condensation, etc.
In industrial production, it is often prepared by [briefly explain the preparation method, which can be supplemented by the reaction of specific raw materials under specific conditions, etc.]. In the process of pharmaceutical research and development, it can be used as a key intermediate to help create new drugs; in the field of materials science, it is also expected to improve the properties of materials, such as improving corrosion resistance. We will continue to study, hoping to make the best use of it for the well-being of the world.
Physical & Chemical Properties
"Introduction to the Physical and Chemical Properties of 2-Amino-5-chlorotrifluorotoluene"
2-Amino-5-chlorotrifluorotoluene is an important substance in chemical research. Its physical properties are in a [specific state at room temperature, because they are not provided to be supplemented], and it has [appearance characteristics such as color, which need to be supplemented]. Its melting point is [specific melting point value, need to be supplemented], and its boiling point is in [specific boiling point range, need to be supplemented]. In terms of solubility, it has a certain solubility in [certain solvent names, need to be supplemented].
In terms of its chemical properties, this substance has a certain reactivity. Due to its content of amino groups, chlorine atoms, and trifluoromethyl groups, amino groups can participate in many nucleophilic reactions, chlorine atoms can undergo substitution reactions, and trifluoromethyl groups affect the electron cloud distribution of molecules, enabling the substance to react with a variety of reagents under specific conditions. For example, with [list some reagents that may react, need to be supplemented], [specific reaction types and products need to be supplemented] occur during [reaction conditions, need to be supplemented], exhibiting unique chemical behavior and significant application potential in the field of organic synthesis.
Technical Specifications & Labeling
2024 is a leap year, with 366 days in the year and 29 days in February. According to the definition of a leap year, a normal year is a leap year that is divisible by 4 but not by 100, and a century year is a leap year that is divisible by 400. 2024 is a normal year, 2024 ÷ 4 = 506, there is no remainder, so 2024 is a leap year.
Preparation Method
If you want to make 2 - Amino - 5 - Chlorobenzotrifluoride, you should first choose the raw materials carefully. 5 - chloro - 2 - nitrotrifluorotoluene can be used as the starting material, and its properties are suitable for this preparation.
Preparation process, first put 5 - chloro - 2 - nitrotrifluorotoluene in a suitable reactor, add an appropriate amount of reducing agent, such as iron and hydrochloric acid formulation, or palladium carbon hydrogenation system, to reduce the reaction. During the reaction, control its temperature and pressure to allow a slow reaction.
After the reduction is completed, the product is separated and purified. By distillation, the impurities are removed to obtain pure 2 - Amino - 5 - Chlorobenzotrifluoride. During this process, the process of reaction is strictly observed and regulated according to time to ensure the quality and quantity of the product. And the maintenance of equipment and the operation of personnel are all about success and failure, and cannot be ignored.
Chemical Reactions & Modifications
Nowadays, there is a chemical substance called 2-amino-5-chlorotrifluorotoluene, which has attracted much attention in the field of chemical industry. In terms of its chemical reaction and modification, it is really the most important for chemical researchers.
In the past, the reaction path of this compound may be complicated and inefficient. Although it can be achieved, it can consume a lot of energy and produce a lot of by-products, which is contrary to today's green chemistry concept.
If you want to improve, you must think of new ways. Or you can find new catalysts to promote efficient reactions and choose directions, reduce energy consumption and by-products. Or work hard on the reaction conditions, adjust the temperature, pressure, and solvent, hoping to optimize the reaction and make it smoother and purer.
In terms of modification, other groups can be introduced and their structures can be changed to expand their use. Or in the industry of materials and medicine, it can generate different energy and increase its value. In this way, this compound can be more suitable for the needs of the world and become the driving force for the development of chemical industry.
Synonyms & Product Names
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The following is a passage created in classical Chinese form about the "synonyms and trade names" of "2-Amino-5-Chlorobenzotrifluoride" products:
There is a thing today called 2-Amino-5-Chlorobenzotrifluoride. This is the essence of chemistry and has a wide range of uses. Its synonyms also have various names, either from its nature, or from its source, all of which are to express its characteristics. As for the name of the product, the merchants have each made a machine to recognize the excellence of their products.
2 - Amino - 5 - Chlorobenzotrifluoride, or 5 - chloro - 2 - aminotrifluorotoluene, which is named after its chemical structure. It is named because of the position of chlorine atom, amino group and trifluoromethyl group. Merchants sell their products, and also create the name of the product, such as [hypothetical trade name 1], [hypothetical trade name 2] and so on. All hope to attract attention with their unique name and occupy a seat in the market.
Chemical things have different names but the same quality. Synonyms and trade names are all to clarify their essence, so that everyone can get a glimpse of the true appearance of this thing in the name of complexity, so as to make use of it and promote the progress of the chemical industry.
Safety & Operational Standards
Husband 2 - Amino - 5 - Chlorobenzotrifluoride, it is also a chemical object. For its safe operation, it cannot be ignored.
Anyone who handles this object should first be safe in the environment. Place it in a good place, avoid open fire, high temperature, and prevent it from exploding. Because of its nature or in case of fire, it will be harmful in case of high temperature, so it will be difficult to operate, and there will be no fire source around, and the degree should be controlled.
The operator also needs to be self-controlled. Use protective clothing, wear eye masks, and gas masks to prevent it from connecting to the skin, entering the eyes, and inhaling. If you accidentally pick up the skin, quickly wash it with a lot of water, and wash it with soap; if it enters the eye, wash it with water immediately, and ask for it as soon as possible.
If it is stored in the skin, it should be densely stored in the dry, oxidized, and acidic materials.
If it is different, it should not be mixed, so as to prevent chemical reactions.




, 2 - Amino - 5 - Chlorobenzotrifluoride It is useful for chemical research or labor, so that it can be safely operated and protected, so as to avoid harm and ensure the safety of people and things.
Application Area
Today there is a product called "2-Amino-5-chlorotrifluorotoluene". This compound has a wide range of uses and is often a key intermediate in the field of pharmaceutical synthesis. It can be used to produce antibacterial drugs to prevent the invasion of pathogens and protect human health. In the field of pesticide creation, it also plays an important role in assisting the research and development of high-efficiency insecticides, removing pests and ensuring crop harvest. And in the field of materials science, it may be used to synthesize materials with special properties to increase the stability and weather resistance of materials. Its wide application is related to many aspects of people's livelihood. It is an indispensable product for chemical research, contributing to the development of various fields and helping the industry move towards new frontiers.
Research & Development
In recent years, I have been in the field of chemistry, focusing on the study of 2 - Amino - 5 - Chlorobenzotrifluoride. Its unique nature has great potential in many fields.
At the beginning, I explored the method of its synthesis, but encountered many difficulties. The choice of raw materials and the rule of reaction all need to be carefully considered. After repeated tests, the path of optimization is finally obtained, and the yield is gradually improved.
Then, study its application. In the pharmaceutical and chemical industry, it can be used as a key intermediate to help create new drugs; in the material science, it can give material-specific properties.
In the future, I hope to use cutting-edge technology to deeply analyze its characteristics and expand the boundaries of application. We hope to join hands with colleagues to promote the development of this product, add brilliance to the chemical industry, and benefit the world.
Toxicity Research
Today there is a thing called 2 - Amino - 5 - Chlorobenzotrifluoride. I am a chemical researcher, specializing in the study of poisons. The toxicity of this thing, I am worried about it, so I tried my best to investigate it.
Observe its properties, detail its reactions, and explore its changes in different media. After many experiments, observe its impact on organisms. Take small animals as a test, observe their state after ingesting this thing, physiological changes, and behavioral differences.
And analyze its diffusion and degradation in the environment, lest it pollute soil and water sources, and endanger all living beings. Although the conclusions obtained are still incomplete, the importance of its toxicity is known. Knowing that the responsibility of poison research is heavy, we must be cautious and cautious to ensure that the world is aware of the danger of this product, prevent problems before they occur, ensure the well-being of all beings, and protect the peace of the environment.
Future Prospects
The future prospect concerns 2-amino-5-chlorotrifluorotoluene. When I look at this substance, the potential is infinite. In the field of chemical industry, it can be used as a key raw material to derive a variety of new products, which seems to open up a new situation for many industries. Medicine, or with its characteristics, can develop special drugs to solve the suffering of everyone. In the field of materials, it is also expected to give birth to novel materials with unique properties and be used in high-tech. Although there may be thorns in the road ahead, I firmly believe that with time and careful study, we will be able to tap its maximum value, bring well-being to the world, achieve extraordinary achievements, and open up bright prospects. This is our future ambition.
Frequently Asked Questions
What are the main uses of 2-Amino-5-Chlorobenzotrifluoride?
2-Amino-5-chlorotrifluorotoluene is also an organic compound. It has a wide range of uses and has important applications in medicine, pesticides, materials and other fields.
In the field of medicine, this compound is often a key intermediate for the synthesis of a variety of specific drugs. For example, some drugs with antibacterial and antiviral effects rely on 2-amino-5-chlorotrifluorotoluene to build a specific chemical structure during the synthesis process to achieve precise pharmacological effects. With this intermediate, the drug can be given better biological activity and targeting, improve drug efficacy, and reduce side effects.
In pesticides, it also plays an important role. With this raw material, high-efficiency, low-toxicity and environmentally friendly pesticides can be created. Such pesticides have strong lethality to crop pests, and can reduce environmental pollution and impact on non-target organisms, ensuring sustainable agricultural development. Its unique chemical structure can optimize the binding ability of pesticide molecules to pest receptors, enhancing insecticidal and bactericidal effects.
In the field of materials, 2-amino-5-chlorotrifluorotoluene can be used to prepare polymer materials with special properties. By polymerizing with other monomers, the material can endow excellent thermal stability, chemical stability and mechanical properties. For example, high-performance materials used in high-end fields such as aerospace, electronics, etc., use this compound to improve material properties and meet specific environmental and functional requirements.
In summary, the unique chemical properties of 2-amino-5-chlorotrifluorotoluene play a key role in many fields, promoting technological progress and innovation in various industries.
What are the physical properties of 2-Amino-5-Chlorobenzotrifluoride?
2-Amino-5-chlorotrifluorotoluene, this substance is one of the organic compounds. Its physical properties are very critical and have a great impact on its performance in various chemical processes and practical applications.
Bear the brunt. Looking at its appearance, under normal temperature and pressure, 2-amino-5-chlorotrifluorotoluene is often colorless to light yellow liquid, with pure texture, uniform appearance and no impurities. This form facilitates its uniform mixing with other substances in various chemical reaction systems, laying the foundation for the smooth progress of the reaction.
Furthermore, when it comes to boiling point. Its boiling point is in a specific temperature range, and this value is related to operations such as distillation and separation. The boiling point of 2-amino-5-chlorotrifluorotoluene reflects the strength of intermolecular forces. The boiling point of 2-amino-5-chlorotrifluorotoluene makes it possible to distinguish it from other substances with large boiling point differences in related chemical processes by temperature control, and to achieve effective separation and purification.
Melting point also cannot be ignored. Knowing its melting point is of great significance in solid storage and processing. A specific melting point indicates that at a certain temperature limit, the substance changes from solid to liquid. Precise control of the melting point can ensure the stability of the material's morphology during storage, and avoid morphological changes due to improper temperature affecting the quality.
Density is also an important physical property. 2-Amino-5-chlorotrifluorotoluene has a specific density. In the liquid mixture system, the density difference can be used for stratification separation and other operations. Through the density data, its proportion in the mixed liquid can be accurately calculated, providing a basis for the design of chemical production formulas.
In terms of solubility, 2-amino-5-chlorotrifluorotoluene exhibits a certain solubility in some organic solvents. This characteristic determines that in the organic synthesis reaction, a suitable solvent can be selected to build a reaction environment, so that the reactants can be fully contacted, the reaction process can be accelerated, and the reaction efficiency and yield can be improved. The physical properties of 2-amino-5-chlorotrifluorotoluene, from its appearance, boiling point, melting point, density to solubility, play a decisive role in its application in the chemical field, and are indispensable in many aspects such as chemical production and organic synthesis.
What are 2-Amino-5-Chlorobenzotrifluoride synthesis methods?
The synthesis method of 2-amino-5-chlorotrifluorotoluene has been around for a long time, and there are many ways. The following details are common.
First, 5-chloro-2-nitrotrifluorotoluene is used as the starting material, which is a commonly used method. Take 5-chloro-2-nitrotrifluorotoluene first, place it in a suitable reaction vessel, and then introduce a suitable reducing agent. It is often reduced by iron powder-hydrochloric acid system, sulfide base, or catalytic hydrogenation. If using iron powder-hydrochloric acid system, pay attention to the regulation of reaction temperature, iron powder dosage and hydrochloric acid concentration. Iron powder needs an appropriate amount, too much is easy to cause impurities to form, and too little is difficult to fully reduce the reaction. The concentration of hydrochloric acid is also particular, too high or too low will affect the reaction process. If the method of catalytic hydrogenation is adopted, the catalyst should be carefully selected, such as palladium carbon, platinum carbon, etc., to control the hydrogen pressure, temperature and reaction time. If the hydrogen pressure is too low, the reaction is slow; if the pressure is too high, there may be a risk of safety. The advantage of this approach is that the raw materials are easy to purchase, and the reaction conditions are relatively mild. However, the post-treatment of the iron powder-hydrochloric acid system may be cumbersome, and the catalytic hydrogenation requires slightly higher equipment.
Second, 2-aminotrifluorotoluene is used 2-Aminotrifluorotoluene is placed in a suitable reaction medium, such as an inert organic solvent, and then chlorinated reagents, such as chlorine gas, sulfuryl chloride, etc. During the reaction, the temperature and the trickle acceleration of the chlorinated reagent are strictly controlled. If the temperature is too high, it is easy to generate polychlorinated by-products; if the trickle addition speed of the chlorinated reagent is too fast, it is also unfavorable to the selectivity of the reaction. The advantage of this approach is that the steps are short, but the control of the reaction conditions is strict, otherwise the side reactions will increase and the product separation and purification will be difficult.
Third, with m-chlorotrifluorotoluene as the starting material, 2-amino-5-chlorotrifluorotoluene is obtained by nitrification and reduction Nitrification of m-chlorotrifluorotoluene is carried out first, and suitable nitrifying reagents, such as mixed acid (mixture of nitric acid and sulfuric acid), are selected to control the reaction temperature and the proportion of nitrifying reagents. Improper temperature or imbalance in the proportion of reagents can cause the position deviation of nitro substitution and generate various isomers. The nitrification product is then reduced, and the reduction method is the same as the above-mentioned reduction method using 5-chloro-2-nitrotrifluorotoluene as raw material. This approach requires attention to the selectivity of nitrification reaction and isomer separation. Although there are many steps, the source of raw materials is wide.
Synthesis of 2-amino-5-chlorotrifluorotoluene is diverse, with advantages and disadvantages. In practical applications, appropriate synthesis methods are carefully selected based on factors such as raw material availability, cost, equipment conditions, and product quality requirements.
What is the price range of 2-Amino-5-Chlorobenzotrifluoride in the market?
2-Amino-5-chlorotrifluorotoluene, the market price, often varies with quality, quantity, time, place and supply and demand conditions. In the market of chemical raw materials, its price fluctuates, and it is difficult to determine the exact number.
Looking at the changes in the price of chemical products in the past, if the quantity is retailed in small quantities, the price may be a few yuan to a few tens of yuan per gram. Due to the process of retailing, it has changed hands through multiple merchants, each adding profit, resulting in a higher price.
If it is purchased in bulk for industrial use, in kilograms, the price may be several hundred yuan per kilogram. Due to large-scale purchases, minus intermediate links, factory-to-factory direct exchange, cost reduction and price reduction.
And its price varies with the price of raw materials, the progress of production and technology, and the needs of the market. If the price of raw materials produced here rises, or environmental protection regulations are strict, resulting in an increase in production costs, the price will also rise. If new products are produced, production rates, costs are reduced, or the market needs to shrink, the price may drop.
To know the exact price, you can consult chemical raw material suppliers, refer to chemical trading platforms for quotations, or find recent price information in industry information to get close to the current market price.
What are 2-Amino-5-Chlorobenzotrifluoride manufacturers?
There are many manufacturers of 2-amino-5-chlorotrifluorotoluene in the world. This compound has a wide range of uses and is used in medicine, pesticides, dyes and other fields, which has attracted many manufacturers to join its production.
In China, there are many powerful manufacturers. Some of them are located in the eastern coastal area, where the chemical industry is developed, the resources are rich, the transportation is convenient, and the production and transportation are extremely beneficial. Some of these manufacturers have won praise in the market with their advanced production technology and strict quality control. Their production process is rigorous, and every step from raw material procurement to finished product output is carefully considered to ensure high product quality.
There are also many such manufacturers abroad. There are several well-known chemical companies in Europe, America and other places involved in this field. They have invested heavily in technological research and development and innovation, continuously optimizing production processes and improving product quality. Their products are not only supplied to the local market, but also sold globally, occupying an important position in the international market.
There are also some emerging manufacturers, although they have been established for a short time, but they have emerged in the market with their flexible business strategies and active application of new technologies. They focus on specific customer groups and provide customized products and services to meet the needs of different customers.
In short, the manufacturers of 2-amino-5-chlorotrifluorotoluene are widely distributed, and each manufacturer has its own characteristics. They have won a place in the market by virtue of their own advantages.