Chemical Formula | C7H5ClF3N |
Molar Mass | 195.57 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | 224 - 226 °C |
Density | 1.365 g/cm³ (approximate) |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Flash Point | 99 °C |
Purity | Typically high - purity products available (e.g., 98%+) |
What are the main uses of 2-Amino-4-Chlorobenzotrifluoride?
2-Amino-4-chlorotrifluorotoluene has a wide range of uses. In the field of medicine, it is often a key intermediate, involved in the preparation of a variety of drugs. For example, some antibacterial drugs, 2-amino-4-chlorotrifluorotoluene, through a series of chemical reactions, can build a unique chemical structure, endow the drug with antibacterial activity, and help fight against pathogens infecting the human body. In the field of pesticides, its role should not be underestimated. It can be used as an important raw material for the synthesis of high-efficiency pesticides. After clever synthesis, the obtained pesticides have a good control effect on crop pests, ensure the growth of crops, and improve yield and quality. In the field of materials science, 2-amino-4-chlorotrifluorotoluene has also emerged. It can be used to prepare materials with special properties, such as some functional polymer materials. Its special chemical structure can endow materials with excellent properties such as chemical corrosion resistance and heat resistance, expand material application scenarios, and play an important supporting role in the chemical industry, promoting technological innovation and development in related fields.
What are the physical properties of 2-Amino-4-Chlorobenzotrifluoride?
2-Amino-4-chlorotrifluorotoluene, this is an organic compound. Its physical properties are quite important and are related to many chemical applications.
Looking at its properties, it is a colorless to light yellow liquid under normal conditions, with a clear appearance and a specific visual appearance. The characteristics of its boiling point are about a certain temperature range. This temperature is the critical value for its transformation from liquid to gaseous state, reflecting the strength of intermolecular forces. The boiling point is of great significance in separation, purification and other operations.
Besides, the melting point is also a key physical property. The melting point is at a certain value, indicating the temperature conditions for the substance to change from solid to liquid. The determination of the melting point helps to identify the purity of the substance. The melting point of the pure product is fixed, and the melting point changes when impurities are present.
In terms of solubility, in organic solvents, such as common ethanol, ether, etc., it exhibits certain solubility characteristics. It can be soluble in such solvents due to the interaction between molecules, which is conducive to chemical reactions in a solution environment. In water, its solubility is poor. Due to the difference between the molecular structure and the polarity of water molecules, the interaction between the two is affected.
Density cannot be ignored either, and it has a certain mass value per unit volume. The size of the density has an important impact on the mixing and delamination of liquids, which is related to the stability and phase distribution of the system.
In addition, 2-amino-4-chlorotrifluorotoluene also has a specific odor, which is difficult to describe accurately, but it is a characterization of its physical properties. This odor is derived from molecular structure and volatility, and has an impact on the operating environment and human sensory experience.
The above physical properties are all indispensable factors in chemical synthesis, material preparation, drug development and other fields, and are of great significance for the understanding and application of this compound.
What is 2-Amino-4-Chlorobenzotrifluoride production method?
The method of preparing 2-amino-4-chlorotrifluorotoluene has also been studied in the past. The way to prepare it is based on the path of chemical synthesis.
One method is to use a specific aromatic hydrocarbon as the starting material. First, the aromatic hydrocarbon interacts with a fluorine-containing reagent under specific reaction conditions to introduce trifluoromethyl. During this step, the temperature, pressure and ratio of the reactants of the reaction need to be carefully controlled. The introduction of trifluoromethyl is quite sensitive to the reaction conditions, and a slight poor pool affects the yield and purity of the product.
Then, chlorine atoms are introduced on the aromatic hydrocarbon. This process also requires the selection of appropriate chlorination reagents and reaction environments. The time and degree of the chlorination reaction are also crucial. Improper chlorination, or the formation of polychlorinated compounds, increases the difficulty of product separation.
After both trifluoromethyl and chlorine atoms are introduced, the amino group is introduced. This step is usually achieved by an amination reaction. Ammonia derivatives can be selected, and they can be reacted with the aforementioned intermediates in the presence of appropriate solvents and catalysts. During the amination reaction, factors such as the polarity of the solvent and the activity of the catalyst all affect the process and result of the reaction.
Another method is to construct a benzene ring structure containing trifluoromethyl first, and then introduce chlorine atoms and amino groups in turn. This approach is slightly different from the former in the order of steps. However, no matter what method is used, each step of the reaction needs to be optimized in detail.
After each step of the reaction, the product needs to be carefully separated and purified. Distillation, recrystallization, column chromatography and other means can be used to remove impurities to obtain pure 2-amino-4-chlorotrifluorotoluene. The optimization of the reaction conditions and the purification of the product in each step are the key to the preparation of this compound, which is related to the quality and yield of the final product.
2-Amino-4-Chlorobenzotrifluoride What are the precautions during storage and transportation?
2-Amino-4-chlorotrifluorotoluene is an important raw material for organic chemistry. During storage and transportation, many key precautions need to be paid more attention.
First, when storing, choose a cool, dry and well-ventilated place. This substance is heat-resistant and moisture-proof, and it is easy to deteriorate or cause chemical reactions due to high temperature or humid environment. If placed in a place with too high temperature, its chemical properties may tend to be active, or there is a risk of decomposition; and moisture intrusion, or reaction with its components, affects the quality.
Second, it should be stored separately from oxidants, acids, bases, etc., and should not be mixed. Due to its special chemical properties, contact with the above substances can easily trigger violent chemical reactions, such as combustion, explosion and other serious accidents. For example, when it encounters a strong oxidizing agent, or triggers a fierce oxidation reaction, a large amount of energy is released in an instant.
Third, the storage container must be tightly sealed. First, to prevent volatilization, this substance has a certain degree of volatility. Volatilization not only causes material loss, but also volatile gases or harmful to health and pollution of the environment; second, to avoid reaction with air components, oxygen, carbon dioxide in the air, etc., or its effect, changing the chemical structure.
Fourth, the transportation process must ensure that the container is stable and free from collision and vibration. Violent vibration or collision may cause damage to the container and material leakage. If it leaks into the environment, or contaminates soil and water sources, and poses a threat to the health of surrounding personnel.
Fifth, transportation vehicles need to be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. In the event of an emergency such as a leak or fire, response measures can be quickly launched to reduce hazards. And transportation personnel should be professionally trained and familiar with the characteristics of the substance and emergency treatment methods.
In short, the storage and transportation of 2-amino-4-chlorotrifluorotoluene must be strictly operated in accordance with regulations and pay attention to details to ensure personnel safety, environmental safety and material quality.
What is the market outlook for 2-Amino-4-Chlorobenzotrifluoride?
2-Amino-4-chlorotrifluorotoluene is an organic compound with specific functions in the chemical industry. Its market prospect needs to be carefully examined from the aspects of supply and demand, application field expansion, etc.
Let's talk about the supply end first. The production of this compound requires specific raw materials and technologies, and strict process control requirements. With the gradual progress of chemical technology, some manufacturers have refined their production processes and increased production capacity. However, the stability of raw material supply, such as specific halides, fluorinated raw materials, etc., is often affected by resource distribution, international situation, etc., resulting in supply fluctuations.
Look at the demand level again. In the field of medicine, many new drug research and development uses 2-amino-4-chlorotrifluorotoluene as the key intermediate to help synthesize drugs with special curative effects. As pharmaceutical innovation continues, demand may rise steadily. In the field of pesticides, this compound is also an important ingredient in the synthesis of high-efficiency and low-toxicity pesticides. With the increasing demand for high-quality pesticides in agriculture, its dosage is expected to expand. Furthermore, in the field of materials science, with the increasing demand for high-performance materials, the preparation of special performance materials as raw materials also opens up new paths for the market.
However, market development is not smooth sailing. Environmental regulations are becoming increasingly stringent, and the production process needs to meet higher environmental standards, increasing production costs. And the competition among peers is fierce, and manufacturers are competing to improve quality and reduce costs to compete for market share.
To sum up, although 2-amino-4-chlorotrifluorotoluene has broad market opportunities due to the expansion of the application field, it also needs to face challenges such as unstable supply, rising environmental protection costs, and intensified competition. If the industry wants to win in the market, it needs to study technology, strictly control costs, and conform to the general trend of environmental protection in order to seek long-term development.