Chemical Formula | C7H5ClF3N |
Molar Mass | 195.57 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | 212 - 214 °C |
Density | 1.375 g/cm³ |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
Flash Point | 92 °C |
Cas Number | 393-11-3 |
What are the main uses of 2-Amino-3-chlorobenzotrifluoride?
2-Amino-3-chlorotrifluorotoluene is also an organic compound. It has a wide range of uses and is often a key raw material for the creation of drugs in the field of medicinal chemistry. With its special chemical structure, it can participate in various reactions, and then build complex molecules with biological activity. For example, when developing antibacterial and anti-inflammatory drugs, this compound can be introduced into the molecular structure of the drug through clever reaction paths, giving the drug specific pharmacological activity and helping it achieve the purpose of treating diseases.
In the field of materials science, 2-amino-3-chlorotrifluorotoluene also has its uses. It can be used as a key structural unit in the synthesis of special functional materials, such as high-performance polymers or optoelectronic materials. By appropriate polymerization or chemical modification, it can be integrated into the molecular structure of the material, which can significantly improve the properties of the material, such as enhancing the stability and solubility of the material, or even endowing the material with unique optical or electrical properties, making the material more suitable for specific application scenarios.
In addition, in the field of pesticide chemistry, this compound also plays an important role. With its chemical properties, it can be used to prepare highly efficient pesticides. After specific synthesis steps, it is converted into pesticide active ingredients with insecticidal, herbicidal or bactericidal effects, providing assistance for pest control in agricultural production and ensuring crop yield and quality. In short, 2-amino-3-chlorotrifluorotoluene has shown important value and application potential in many fields.
What are the physical properties of 2-Amino-3-chlorobenzotrifluoride?
2-Amino-3-chlorotrifluorotoluene is one of the organic compounds. Its physical properties are quite impressive, as detailed below.
First appearance, at room temperature, it is mostly colorless to light yellow liquid, with a clear texture, like a clear spring. It can be seen that its fluidity is good, and there is no obvious viscous state. This appearance characteristic is the primary discrimination basis for the observation and operation of chemical production.
times and boiling point, about a specific temperature range, the value of this temperature depends on accurate experimental determination. The boiling point is the critical temperature at which a substance changes from liquid to gas state, which is related to its distillation, separation and other process operations. In this compound, the characteristics of the boiling point determine the phase transition under specific temperature conditions, which is crucial in industrial purification and other processes.
Furthermore, the melting point is also an important physical parameter. Although the exact melting point requires rigorous experiments to obtain accurate values, it characterizes the boundary between the solid and liquid state transitions of compounds. The level of melting point is closely related to intermolecular forces, crystal structures and many other factors. The melting point of this compound affects its storage and transportation conditions.
In terms of solubility, organic solvents such as alcohols and ethers often exhibit good solubility, just like fish get water and blend seamlessly. This property makes it possible to build a homogeneous reaction system with the help of suitable organic solvents in organic synthesis reactions to promote the smooth progress of the reaction. However, in water, the solubility is relatively limited, which is caused by factors such as molecular polarity, just like the insolubility of oil and water, each in its place.
Density is also a physical property that cannot be ignored. After accurate measurement, a specific value can be obtained. This value is related to the stratification phenomenon when mixed with other substances, volume calculation and other practical applications. In the process of chemical production, such as material ratio and reactor filling, accurate consideration of density is indispensable.
In addition, its odor may have a special aromatic smell, although it is not strongly pungent, it needs to be treated with caution, because some aromatic compounds may have potential effects on human senses and health.
The physical properties of 2-amino-3-chlorotrifluorotoluene play a key role in many aspects of chemical synthesis, storage, transportation and application, and need to be carefully grasped by practitioners before they can be properly utilized.
What is the chemistry of 2-Amino-3-chlorobenzotrifluoride?
2-Amino-3-chlorotrifluorotoluene is an important compound in the field of organic chemistry. This substance has unique chemical properties and plays a key role in many chemical processes and industrial applications.
First discuss its physical properties, 2-amino-3-chlorotrifluorotoluene is usually a colorless to light yellow liquid with a special odor. The values of its boiling point and melting point are of great significance for controlling the relevant reaction conditions and product purification process. The boiling point varies depending on the ambient pressure, but at standard pressure, it is roughly in a specific temperature range. This temperature characteristic determines its behavior in separation operations such as distillation. The melting point is also a specific value, which affects the physical morphology of the substance under different temperature conditions.
In terms of chemical properties, the presence of amino groups (-NH2O), chlorine atoms (-Cl) and trifluoromethyl groups (-CF 🥰) endows this compound with diverse reactivity. Amino groups are nucleophilic groups, which can participate in many nucleophilic substitution reactions, such as reacting with halogenated hydrocarbons to form new carbon-nitrogen bonds, thereby forming complex organic molecular structures. At the same time, amino groups can also participate in acylation reactions, interacting with acyl chlorides or acid anhydrides to form corresponding amide products.
Although chlorine atoms are electron-withdrawing groups, nucleophilic substitution reactions can occur under suitable conditions. In the presence of strong bases or specific catalysts, chlorine atoms can be replaced by other nucleophiles, such as by hydroxy (-OH) to form phenolic derivatives; or by alkoxy (-OR) to obtain ether compounds. The introduction of
trifluoromethyl greatly changes the electron cloud distribution and spatial structure of the molecule. Due to its strong electron-absorbing effect, the electron cloud density of the benzene ring is reduced, which in turn affects the reactivity of other substituents on the benzene ring. This structural property makes 2-amino-3-chlorotrifluorotoluene exhibit unique selectivity in some chemical reactions. In the field of drug synthesis, it is helpful to design and synthesize molecules with specific biological activities.
In addition, the stability of 2-amino-3-chlorotrifluorotoluene is also worthy of attention. Although its structure is relatively stable, chemical reactions may still occur under extreme conditions such as high temperature, strong acid, strong base or strong oxidant, resulting in molecular structure changes. Therefore, when storing and using this compound, it is necessary to pay attention to environmental conditions to prevent its deterioration or dangerous reactions.
In conclusion, 2-amino-3-chlorotrifluorotoluene has been widely used in many fields such as organic synthesis, medicinal chemistry, and materials science due to its unique physical and chemical properties, providing an important chemical basis for the development of related fields.
What is 2-Amino-3-chlorobenzotrifluoride production method?
The preparation method of 2-amino-3-chlorotrifluorotoluene is described in the ancient books, and the following methods are followed.
First, the compound containing benzene ring is used as the starting material, and the halogenation method is carried out. First, the appropriate benzene derivative is taken, and the chlorine atom is introduced under specific reaction conditions. This halogenation step often requires precise regulation of the reaction temperature, pressure and the amount of halogenating reagent. Commonly used halogenating reagents such as chlorine gas and thionyl chloride are used in a catalytic environment to chlorinate specific positions of the benzene ring to generate chlorine-containing benzene derivatives.
Then, trifluoromethylation is performed. This process is crucial. A reagent containing trifluoromethyl, such as trifluoromethyl halide, reacts with the halogenated benzene derivative with the help of a catalyst. The catalyst may be a metal salt, or a complex of specific organic ligands and metals, which promotes the smooth integration of trifluoromethyl into the benzene ring to obtain benzene compounds containing trifluoromethyl and chlorine.
Furthermore, an amino group is introduced into the molecule. Nitro can be converted into amino groups by various methods, such as replacing hydrogen atoms on the benzene ring with nitro groups, and through reduction reaction. When nitrifying, choose a suitable nitrifying agent, such as a mixed acid system of nitric acid and sulfuric acid, and operate at a suitable temperature range to introduce nitro groups at specific positions in the benzene ring. After that, by reduction means, such as the reduction system composed of metals (such as iron, zinc, etc.) and acids (such as hydrochloric acid), or under the condition of catalytic hydrogenation, the nitro group is reduced to an amino group, and the final product is 2-amino-3-chlorotrifluorotoluene.
Or there is another method, using existing compounds with similar structures as raw materials, through functional group conversion. First, take benzene derivatives with similar structures, modify and transform existing functional groups through specific reactions, and gradually build the structure of the target molecule. After multi-step reactions, the final product is 2-amino-3-chlorotrifluorotoluene. All methods have their own advantages and disadvantages, and need to be selected according to actual needs, raw material availability and cost considerations.
What is the price range of 2-Amino-3-chlorobenzotrifluoride in the market?
2-Amino-3-chlorotrifluorotoluene is on the market, and its price range is difficult to determine. The price of this product often changes due to various reasons, such as the price of raw materials, the method of preparation, the situation of supply and demand, and even the competition of the city and the regulations of the government.
Looking at the price of chemical raw materials in the past, it fluctuates quite a lot. If the raw materials are abundant and the preparation method is simple and efficient, and the supply exceeds the demand, the price may decline; on the contrary, if the raw materials are scarce and the production method is complicated, and there are many seekers, the price will rise.
Now if you want to know the exact price of 2-amino-3-chlorotrifluorotoluene, you should carefully observe the real-time market conditions of the chemical market. You can visit the chemical product trading platform, consult various suppliers, and receive quotations from multiple parties. Mutual reference can be used to obtain the approximate price. Or you can participate in chemical industry exhibitions and seminars, and consult with industry experts to find out the approximate price. But even if you get the current price, it is difficult to determine its durability, because it is affected by the above reasons, and there may be changes from time to time.