1 Butanesulfonyl Fluoride
Fluoride

1-Butanesulfonyl Fluoride

Duxiu Chemical

Specifications

HS Code

704695

Chemical Formula C4H9SO2F
Molar Mass 140.18 g/mol
Appearance Colorless to pale yellow liquid
Boiling Point 173 - 174 °C
Density 1.17 g/cm³
Solubility In Water Reacts with water
Solubility In Organic Solvents Soluble in many organic solvents
Flash Point 74 °C
Vapor Pressure Low vapor pressure
Acidity Basicity Sulfonyl fluoride group can be reactive in some acid - base related reactions
Odor Pungent odor
Packing & Storage
Packing 100 mL bottle of 1 - Butanesulfonyl Fluoride, well - sealed for chemical storage.
Storage 1 - Butanesulfonyl fluoride should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly sealed container to prevent leakage and exposure to air or moisture. Store it separately from incompatible substances like oxidizing agents, bases, and reactive metals to avoid potential chemical reactions.
Shipping 1 - Butanesulfonyl Fluoride is a chemical that requires careful shipping. It should be packaged in appropriate, leak - proof containers, transported in accordance with hazardous chemical regulations, ensuring safety during transit.
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1-Butanesulfonyl Fluoride
General Information
Historical Development
The origin of 1-butane sulfonyl fluoride can be traced back to the past. At the beginning, few people knew about it in the field of chemical exploration. However, with the evolution of chemistry, wise people devoted themselves to studying. At that time, although technology was not as prosperous as it is today, scholars still tried it repeatedly in the laboratory with tenacity. After years of hard work, its properties have gradually become clear. It is known that it has unique effects in specific chemical reactions. As time went by, more chemists set foot in this field, the research became more in-depth and the application became more and more extensive. From its initial accidental discovery to becoming an indispensable material in chemical research, the development of 1-butane sulfonyl fluoride is a brilliant stroke in the history of chemistry, witnessing the unremitting pursuit of knowledge and the brilliance of human wisdom.
Product Overview
1-Butane sulfonyl fluoride is an organic compound. It is a colorless liquid with a specific odor. This substance is active and has many reactions. In the field of organic synthesis, it is often an important agent. It can react with alcohols, amines and other substances to form a genus of sulfonates and sulfonamides.
The method of its preparation, or it is obtained by the interaction of butane sulfonic acid and fluorination reagents. When preparing, it is necessary to strictly control the reaction conditions, such as temperature and the ratio of reagents, in order to obtain high-yield products.
In the industrial process, 1-butane sulfonyl fluoride is used to make medicines, pesticides and special materials. However, it is toxic and corrosive to a certain extent. When used, follow safety regulations to prevent harm to people and the environment.
Physical & Chemical Properties
1 - Butanesulfonyl Fluoride is also a compound. Its substance has physical and chemical properties, which can be studied. Looking at its shape, under normal conditions, it may be a transparent liquid, with fluidity, like water and different in quality. In terms of its properties, the melting point and boiling point are fixed. If the melting point is low, it will be easy to melt in cold; if the boiling point is not high, it will be easy to gas when heated. And its density is heavier than water, and if placed in water, it will sink.
And its chemical activity, it can react in case of alkali, and the sulfonyl fluoride group in the molecular structure is important, which makes it unique to combine with other substances. In the field of organic synthesis, it is often a key agent, contributing to the formation of a variety of compounds, and is a key ingredient in the chemical industry. It is widely used in materials research and development, pharmaceutical creation, and many other things. Its physical and chemical properties are indeed something that researchers should investigate in detail.
Technical Specifications & Labeling
1 - Butanesulfonyl Fluoride is a unique chemical quality. Its process specifications are related to many details, the first priority is its purity, which needs to reach the highest standard, and impurities must not disturb its purity. Appearance also requires, and it should have a specific color and shape, without the slightest deviation.
Its product parameters are precise and strict, such as molecular weight, density, etc., are clearly defined. In terms of detection marks, it is necessary to test its various indicators with accurate methods. With advanced instruments, its chemical properties are carefully measured to ensure that they conform to the established process specifications. The identification needs to specify the parameters, so that the user can see at a glance, and there is no mistake. In this way, the high quality of 1-Butanesulfonyl Fluoride can be guaranteed, and its ability can be fully demonstrated in various applications.
Preparation Method
The method of making 1-Butanesulfonyl Fluoride is related to the raw materials and production process, reaction steps and catalytic mechanism. First take butane, and introduce the sulfonic acid group by the method of sulfonation. This is the key starting point. Use a specific reagent to make butane and sulfur-containing reagents encounter, control temperature and pressure, and promote the reaction. After obtaining butane sulfonic acid, fluoride. Choose a suitable fluorinating agent, add it to the reaction system in sequence, and pay attention to the reaction rate and process. By means of a catalytic mechanism, use a suitable catalyst to reduce the reaction energy barrier and improve the reaction efficiency. Each step of the reaction is carefully observed and regulated according to time. Follow this step to obtain 1-Butanesulfonyl Fluoride. The process needs to be refined to achieve optimum effect.
Chemical Reactions & Modifications
1 - Butanesulfonyl Fluoride is an important chemical substance that has attracted much attention in the field of chemical research. Its chemical reaction is unique and contains many things that can be investigated.
Looking at the reaction, it can be found that it can interact with a variety of reagents under specific conditions. However, the reaction is sometimes unsatisfactory, and there are areas for improvement. For example, the reaction rate may be unsatisfactory, resulting in sub-optimal product generation efficiency. And the reaction selectivity may be insufficient, which is easy to produce by-products and affect the purity of the target product.
The way to improve can start from the reaction conditions. Try to adjust the temperature, pressure, or optimize the reaction process. Or explore a more suitable catalyst to reduce the activation energy of the reaction and improve the reaction rate and selectivity. In this way, it is expected to optimize the chemical reactions related to 1-Butanesulfonyl Fluoride, which will significantly improve its performance and play a greater role in chemical synthesis and other fields.
Synonyms & Product Names
1 - Butanesulfonyl Fluoride, which is very important in chemical research. Its synonymous name and trade name are both valued by researchers. In ancient academic inheritance, the identification of names is crucial, and the same thing has different names, which often leads to confusion. Today 1 - Butanesulfonyl Fluoride, or another name, is widely communicated in the academic community. Its trade name is also a symbol for inter-city circulation. Although the names are different, they all refer to the same thing. The uses of various names are suitable for each other, and they all have their own significance when studied in business. Clear its synonymous name and trade name, such as pilotage lamp, enable scholars to travel in the ocean of chemical industry, not be fascinated, research in an orderly manner, and its utility is widely spread in the world.
Safety & Operational Standards
1 - Butanesulfonyl Fluoride is also a chemical substance. Its safe operation is essential.
Before use, the animal must first be cleared. This chemical substance is dangerous to a certain extent. If it is exposed to the skin, it should be washed with a lot of water immediately, and it should be kept clean. If it is not carefully entered into the eyes, it is also necessary to wash it with water quickly. It may widen the eyes, so that the water can fully wash the eyes. It is necessary to ask for it.
The operation of the product needs to be well-managed. Avoid inhalation of the product or steam. It is appropriate to have a suitable arrangement to reduce the degree of harmful substances. After use, seal and store it properly, and place it in the product, dry and childlike method.
Furthermore, if there is a leakage accident, do not panic. Immediately evacuate the surrounding area and cut off the fire source. Small leaks can be absorbed by inert materials such as sand and vermiculite and collected in a combined container. Large leaks need to be contained in embankments or excavations, and covered with foam to reduce the damage of steaming.
Only by maintaining safe operation can the use of 1-Butanesulfonyl Fluoride be effective and safe, avoid accidents, and ensure the safety of workers and the safety of the environment.
Application Area
1-Butane sulfonyl fluoride is now a chemical wonder. Its application field involves a wide range of things. In the field of medicine, or it can be the foundation for the development of medicinal stones, helping to heal diseases and diseases. With its uniqueness, it can participate in the wonder of preparations, the properties of drug adjustment, increase its effectiveness and reduce its harm.
In the road of engineering and technology, it is also very useful. It can be used as an agent for material improvement, making the material heterogeneous, or increasing its strength, or adding its softness, or giving it the ability to resist corrosion. And in the industry of dyeing and weaving, or it can change the properties of dyes, making it strong and fresh.
And in the realm of scientific research, it is a weapon for exploring the unknown. Assistants analyze the minutiae of things and dissolve the secrets of change. Through the passage of time, it is expected to bloom in the fields of various uses and contribute to the progress of the world.
Research & Development
Today there is a substance called 1-Butanesulfonyl Fluoride. As a chemical researcher, I often study the properties of this substance.
Looking at its research and development, this compound is gradually showing its potential in the chemical industry. Its structure is unique and its properties are also considerable. After repeated experiments, its reaction mechanism has been observed, and it has been shown that it can participate in many key chemical reactions under specific conditions, providing opportunities for the synthesis of new materials.
In terms of development, many scholars are working to expand its application scope. It can be used to optimize the catalytic reaction process, or try to integrate high-tech materials into the preparation, hoping to explore more potential value. Over time, with the deepening of research, 1-Butanesulfonyl Fluoride will add a strong touch to the development of the chemical industry.
Toxicity Research
1-Butane sulfonyl fluoride is also a chemical substance. It is quite important for toxicity research. Now study its properties in detail to understand its impact on all things in the world.
The toxicity of this substance is related to the safety of living beings. After many tests, it has been observed that it may not be harmful at the end of the dose; however, if the amount is increased, it may cause various changes. In plants and trees, it may cause their vitality to be blocked, leaves to wither and stems to wither; in insects, or disrupt their physiological order, and their fate is worrying.
And it is not stable in the environment. Or migrate with water, or float away with the wind, enter rivers, lakes and seas, and soak in soil and rock layers. If it accumulates for a long time, it will lead to ecological imbalance and endanger the survival of all things. Therefore, it is urgent to study its toxicity, hoping to find a proper way to control its harm and promote its benefits, protect the safety of life in the world, and protect the natural environment.
Future Prospects
Today there is a thing called 1 - Butanesulfonyl Fluoride. Although this chemical thing has not yet revealed its full picture in the present, its future development can be looked forward to.
Looking at all the new things in the past, when it first started, it was little known. After being studied by wise men and skilled craftsmen, it eventually shone brightly and benefited the world. 1 - Butanesulfonyl Fluoride should be the same. In time, it will be able to develop its talents in various fields.
Or in the road of medicine, help heal diseases; or in the world of materials, add new substances to creation. Although the road ahead is uncertain, the opportunity it contains is like a star in the dark night, hidden and waiting to be revealed. We should have the heart of expectation, and wait for it to bloom in the years to come, to be used by the world, and to achieve extraordinary deeds.
Frequently Asked Questions
What are the main uses of 1-Butanesulfonyl Fluoride?
1-Butanesulfonyl fluoride is widely used. It is an important reagent in the field of organic synthesis. Due to its active chemical properties, it can participate in many key reactions, such as nucleophilic substitution reactions with compounds containing active hydrogen, such as alcohols and amines. Through such reactions, a variety of organic compounds with unique structures can be constructed. In the field of medicinal chemistry, it helps to develop new drug molecules and contributes to human health.
In the field of materials science, 1-butanesulfonyl fluoride is also indispensable. It can be used as a functionalizing reagent to modify the surface of materials. After modification, the properties of the material surface, such as wettability and anti-adhesion, can be significantly regulated. For example, in the preparation of special coating materials, the introduction of 1-butane sulfonyl fluoride can make the coating have excellent water and oil repellent properties, and is widely used in fabric finishing, building material protection and many other aspects.
Furthermore, in the preparation of surfactants, 1-butane sulfonyl fluoride also plays an important role. By introducing it into the molecular structure of surfactants through appropriate chemical reactions, it can improve the performance of surfactants, enhance its ability to reduce surface tension, and then enhance its efficacy in emulsification, dispersion, solubilization, etc. It is widely used in daily chemical, petroleum extraction and other industries.
What are the physical properties of 1-Butanesulfonyl Fluoride?
1-Butane sulfonyl fluoride, its physical properties are quite important and related to many practical applications. Under normal temperature and pressure, this substance is usually in the form of a colorless to slightly yellow liquid, with a clear appearance, as pure as morning dew.
Looking at its density, it is between 1.15 and 1.25 g/cm ³, just like a carefully adjusted density balance, giving it a unique sense of weight. Its boiling point is about 160-170 ° C. At this temperature, it is like a butterfly breaking a cocoon, sublimating from liquid to gaseous. The melting point is around -30 ° C, just like sleeping in a low temperature, waiting for the right temperature to wake up.
1-butane sulfonyl fluoride has a certain solubility, soluble in some organic solvents, such as ether, acetone, etc., just like fish in water. However, its solubility in water is extremely limited, just like the incompatibility of oil and water.
The vapor pressure of this substance is relatively low at room temperature, which means that its volatilization degree is relatively moderate, and it does not spread rapidly like wind and rain. Its refractive index also has a specific value, about 1.38-1.42. When the light passes through, it is like a smart dance, refracting at a unique angle.
In addition, 1-butane sulfonyl fluoride also has a unique smell. Although it is not strong and pungent, it can still be keenly perceived, just like a faint fragrance, vaguely lingering on the tip of the nose. Its various physical properties are like a delicate picture, providing a key foundation for scientific research and industrial applications.
Is 1-Butanesulfonyl Fluoride Chemically Stable?
1-Butane sulfonyl fluoride, this physical property belongs to the active class and is not extremely stable. The reason for its activity is due to the intra-molecular structure.
Looking at its structure, in the sulfonyl fluoride group (-SO 2O F), the sulfur atom is connected to two oxygen atoms and one fluorine atom. The fluorine atom is extremely electronegative and attracts electrons very strongly, resulting in a decrease in the density of the electron cloud around the sulfur atom and a positive electricity. This positive sulfur atom is vulnerable to attack by nucleophiles, which then triggers a reaction. For example, when encountering nucleophiles such as alcohols and amines, a nucleophilic substitution reaction can occur, and the fluorine atom is replaced to form a new compound.
Furthermore, although the carbon chain part of the molecule is relatively stable, the activity of the sulfonyl fluoride group is sufficient to affect the overall stability. Under appropriate conditions, such as specific pH and temperature environments, it may promote the reaction to occur. When the temperature rises, the thermal movement of the molecule intensifies, the activity of the sulfonyl fluoride group is even more severe, and the reaction rate is also accelerated.
Therefore, the chemical properties of 1-butane sulfonyl fluoride are not stable. Under the influence of many conditions, it is easy to participate in various chemical reactions and exhibit its active chemical properties.
What is the production method of 1-Butanesulfonyl Fluoride?
The preparation method of 1-butane sulfonyl fluoride is a key issue in chemical technology. In the past, the preparation of this substance often followed various paths.
One method can also be obtained by the interaction of butane sulfonic acid with fluorinated reagents. Butane sulfonic acid has an active sulfonic acid group. When encountering specific fluorinated reagents, such as pyridine hydrofluoride (Py · HF), the hydroxyl group in the sulfonic acid group can be replaced by fluorine atoms. Through this substitution reaction, 1-butane sulfonyl fluoride is produced. This reaction process requires careful temperature control. Because pyridine hydrofluoride is quite active and corrosive, if the temperature is too high, it may cause side reactions and the product is impure. If the temperature is too low, the reaction rate will be slow and time-consuming. Generally speaking, temperature control in a moderate range, such as 0 ° C to 20 ° C, can make the reaction proceed smoothly and obtain better yields.
There are also those who use butane sulfonyl chloride as raw material. Butane sulfonyl chloride and fluoride salts, such as potassium fluoride and sodium fluoride, in a suitable solvent, such as dimethyl sulfoxide (DMSO), through nucleophilic substitution reaction, the chlorine atom is replaced by the fluorine atom, and finally 1-butane sulfonyl fluoride. In this reaction, the choice of solvent is crucial. Dimethyl sulfoxide can promote the reaction due to its good solubility and activation of ions. However, it is also necessary to pay attention to the anhydrous environment of the reaction system. Due to the existence of water or the hydrolysis of fluoride salts, it is often necessary to operate in a dry environment.
In addition, there are still phase transfer catalysts. In the above reaction, adding a phase transfer catalyst, such as tetrabutylammonium bromide, can enhance the mass transfer of the reactants between the two phases, and improve the reaction rate and yield. The phase transfer catalyst acts as a medium, making it easier for reactants that are originally difficult to contact in different phases to interact and accelerate the formation of 1-butane sulfonyl fluoride. These methods have their own advantages and disadvantages. In actual preparation, it is necessary to choose the best one according to the availability of raw materials, cost considerations, product purity requirements and other factors.
What are the precautions for 1-Butanesulfonyl Fluoride during use?
For 1-butane sulfonyl fluoride, there are a number of things to pay attention to when it is used.
First, this substance is toxic, and it can be harmful to the body if touched, smelled or swallowed by mistake. When handling, be sure to wear protective gear, such as gloves, goggles, gas masks, etc., to separate it from the body. And when it is used in a well-ventilated place to prevent its gas accumulation and damage people's health.
Second, 1-butane sulfonyl fluoride is chemically active, and it is easy to react violently when exposed to heat, open flames or strong oxidants, and may even cause the danger of explosion. Therefore, when avoiding heat sources and fire sources, do not mix with oxidants. When using it, you must also be careful to avoid hot topics and open flames, and operate according to the procedures to prevent accidents.
Third, it may have an impact on the environment. When it is used up, it should not be discarded at will. When in accordance with relevant regulations, take proper measures. Or recycle, or hand it over to a qualified institution for disposal to avoid polluting the environment.
Fourth, handling 1-butane sulfonyl fluoride requires professional knowledge and skills. Before use, be sure to clarify its nature, reaction characteristics and emergency measures. In case of accidents, such as leakage, fire, etc., appropriate measures can be taken quickly to minimize damage. In this way, the process of using 1-butane sulfonyl fluoride is safe and smooth.